100704-药物分析学

与药物不良反应相关的药物代谢/转运机制研究
药物代谢新途径化学和生物学基础研究
药物代谢与动力学新方法研究

1994-09--1999-07   沈阳药科大学   博士学位
1990-09--1994-07   沈阳药科大学   学士学位

   

2005-05~现在, 中科院上海药物研究所, 研究员，课题组长
1999-08~2005-04,沈阳药科大学, 讲师、副教授、教授
1994-09~1999-07,沈阳药科大学, 博士学位
1990-09~1994-07,沈阳药科大学, 学士学位

2016-01-01-2019-01-01,上海市药学会理事会理事,
2015-12-01-今,上海药学会药物分析专业委员会副主任委员,
2015-10-01-今,中国药学会药物分析专业委员会委员,
2014-05-01-今,上海药理学会药物代谢专业委员会副主任委员,
2013-05-01-今,中国药科大学校外兼职导师,

药物代谢

   

（1） 2015年上海科技系统“三八红旗集体”, 省级, 2015
（2） 上海药学科技一等奖, 一等奖, 省级, 2014
（3） 几种手性药物的高效液相色谱分析, 三等奖, 省级, 2004
（4） 108种制剂的药物动力学和生物, 二等奖, 省级, 2003

（ 1 ） 酰胺类化合物及其制备方法和用途, 2022, 第 7 作者, 专利号: 202210267217.3

（ 2 ） 吲哚-1-碳酸酯类化合物、其制备方法和应用, 2018, 第 2 作者, 专利号: CN108250187A

   

（1） Mechanistic Study on the Effect of Renal Impairment on the Pharmacokinetics of Vildagliptin and its Carboxylic Acid Metabolite, PHARMACEUTICAL RESEARCH, 2022, 通讯作者
（2） Qualitative and quantitative determination of the primary active components and metabolites in human plasma after oral administration of Shuanghuanglian liquid, JOURNAL OF SEPARATION SCIENCE, 2022, 通讯作者
（3） Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities, PHARMACEUTICS, 2022, 通讯作者
（4） Non-cytochrome P450 enzymes involved in the oxidative metabolism of xenobiotics: Focus on the regulation of gene expression and enzyme activity, PHARMACOLOGY & THERAPEUTICS, 2022, 通讯作者
（5） LC-MS/MS assay of fluoropezil and its two major metabolites in human plasma: an application to pharmacokinetic studies, BIOANALYSIS, 2022, 通讯作者
（6） Simultaneous determination of almonertinib and its active metabolite HAS-719 in human plasma by LC-MS/MS: Evaluation of pharmacokinetic interactions, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2022, 通讯作者
（7） Effect of Itraconazole and Rifampicin as CYP3A Modulators but not P-gp Modulators on the Pharmacokinetics of Almonertinib and Active Metabolite HAS-719 in Healthy Volunteers, Acta Pharmacologica Sinica, 2021, 通讯作者
（8） TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models, AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 第 8 作者
（9） Desorption electrospray ionization (DESI) source coupling ion mobility mass spectrometry for imaging fluoropezil (DC20) distribution in rat brain, ANALYTICALANDBIOANALYTICALCHEMISTRY, 2021, 通讯作者
（10） Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients, BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2021, 通讯作者
（11） Dual action of acidic microenvironment on the enrichment of the active metabolite of disulfiram in tumor tissues, DRUG METABOLISM AND DISPOSITION, 2021, 通讯作者
（12） Metabolic Activation of Retrorsine may Disrupt Bile Acid Homeostasis in Mice through the Nrf2 Pathway, CURRENT DRUG METABOLISM, 2021, 通讯作者
（13） Development of Novel N-hydroxypyridone Derivatives as Potential Anti-Ischemic Stroke Agents, JOURNAL OF MEDICINAL CHEMISTRY, 2020, 第 16 作者
（14） CYP2C and CYP2B Mediated Metabolic Activation of Retrorsine in Cyp3a Knockout Mice, CURRENT DRUG METABOLISM, 2020, 通讯作者
（15） Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor, BIOMEDICINE & PHARMACOTHERAPY, 2020, 第 5 作者
（16） Effects of Apatinib on the Pharmacokinetics of Nifedipine and Warfarin in Patients with Advanced Solid Tumors, DRUG DESIGN DEVELOPMENT AND THERAPY, 2020, 第 10 作者
（17） The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor, EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 第 4 作者
（18） 辛伐他汀片空腹和餐后给药人体生物等效性研究, Bioequivalence study of simvastatin tablets in healthy Chinese volunteers, 中国新药杂志, 2020, 第 5 作者
（19） Original Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor, BIOMEDICINE & PHARMACOTHERAPY, 2020, 第 5 作者
（20） Qualitative and quantitative determination of anaprazole and its major metabolites in human plasma, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 通讯作者
（21） LC-MS/MS法同时测定人血浆中倍赛诺他及其N-羟基酰胺水解代谢物M351, Simultaneous determination of bisthianostat and its hydrolyzed N-hydroxyamide metabolite M351 in human plasma by liquid chromatography-tandem mass spectrometry(LC-MS/MS), 药学学报, 2020, 第 9 作者
（22） Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability, BIOMEDICAL CHROMATOGRAPHY, 2020, 通讯作者
（23） Direct quantification of anorethidrani disuccinate and determination of sterol metabolites by chemical derivatization combined with LC-MS/MS: Application to a Phase I pharmacokinetic study in humans, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 第 5 作者
（24） LC-MS/MS法测定血浆及耳溢液中帕珠沙星：滴耳液药动学研究, LC-MS/MS analysis of pazufloxacin in human plasma and otorrhea:application to a pharmacokinetic study of ear drops, 药学学报, 2020, 第 5 作者
（25） Nimesulide increases the aldehyde oxidase activity of humans and rats, Nimesulide increases the aldehyde oxidase activity of humans and rats, ACTA PHARMACOLOGICA SINICA, 2020, 通讯作者
（26） A sensitive LC-MS/MS method for the determination of triptolide and its application to pharmacokinetic research in rats, BIOMEDICAL CHROMATOGRAPHY, 2019, 第 2 作者
（27） Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein, metabolismanddispositionofpyrotinibinhealthymalevolunteerscovalentbindingwithhumanplasmaprotein, ACTA PHARMACOLOGICA SINICA, 2019, 其他（合作组作者）
（28） Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing, EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 第11作者
（29） Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 第 3 作者
（30） Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans, DRUG METABOLISM AND DISPOSITION, 2019, 通讯作者
（31） Study of pharmacokinetics and cutaneous photosensitization of hemoporfin in healthy volunteers, PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2019, 第 8 作者
（32） Effect of ethnicity on vinorelbine pharmacokinetics: a population pharmacokinetics analysis, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2019, 第 3 作者
（33） Current trends in drug metabolism and pharmacokinetics, ACTA PHARMACEUTICA SINICA B, 2019, 通讯作者
（34） Simultaneous determination of imrecoxib and its two active metabolites in plasma of hepatic impairment patients by liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2019, 通讯作者
（35） Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases, DRUGMETABOLISMANDDISPOSITION, 2019, 通讯作者
（36） Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 第 3 作者
（37） Enantioselective determination of ketamine in dog plasma by chiral liquid chromatography-tandem mass spectrometry, BIOMEDICAL CHROMATOGRAPHY, 2019, 通讯作者
（38） Bioequivalence of paclitaxel protein-bound particles in patients with breast cancer: determining total and unbound paclitaxel in plasma by rapid equilibrium dialysis and liquid chromatography–tandem mass spectrometry, DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 通讯作者
（39） Bioequivalence of Oral Formulations of Anastrozole in Healthy Chinese Male Volunteers: A Randomized, Single-Dose, Two-Period, Two-Sequence Crossover Study, CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2019, 第 4 作者
（40） 共价酪氨酸激酶抑制剂的代谢和药动学, Metabolism and pharmacokinetics of covalent tyrosine kinase inhibitors, 药学学报, 2019, 第 2 作者
（41） LC-MS/MS法测定人血浆中硝苯地平和去氢硝苯地平, Rapid and simultaneous determination of nifedipine and dehydronifedipine in human plasma, 药学学报, 2019, 第 3 作者
（42） Mechanism of Reductive Metabolism and Chiral Inversion of Proton Pump Inhibitors, DRUG METABOLISM AND DISPOSITION, 2019, 通讯作者
（43） Pharmacokinetics and tissue distribution of eupatilin and its metabolite in rats by an HPLC-MS/MS method, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 第 6 作者
（44） Effect of Fluconazole on the Pharmacokinetic Properties of Imrecoxib, a Novel NSAID: A Single-center, Open-label, Self-controlled Study in Healthy Chinese Male Volunteers, CLINICAL THERAPEUTICS, 2018, 通讯作者
（45） Development and validation of a sensitive and rapid UHPLC–MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 第11作者
（46） Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate, DRUG METABOLISM AND DISPOSITION, 2018, 通讯作者
（47） 不同给药途径灯盏乙素及其代谢物在大鼠体内处置差异研究, Comparative study of disposition of scutellarin and its major metabolite with different administration routes in rats, 药学学报, 2018, 第 5 作者
（48） 甲磺酸多黏菌素E 2组分的色谱分离及质谱裂解规律研究, Chromatographic Separation and Fragmentation Mechanism in Electrospray Ionization Mass Spectrometry for Colistin B Methanesulfonate, 质谱学报, 2018, 第 4 作者
（49） LC-MS/MS法同时测定人血浆中福沙匹坦和代谢物阿瑞匹坦, Simultaneous determination of fosaprepitant and its metabolite aprepitant in human plasma by liquid chromatography-tandem mass spectrometry, 药学学报, 2018, 第 3 作者
（50） Pharmacokinetic Drug Interactions of Apatinib With Rifampin and Itraconazole, JOURNAL OF CLINICAL PHARMACOLOGY, 2018, 第 9 作者
（51） CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats, CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats, ACTA PHARMACOLOGICA SINICA, 2018, 第 3 作者
（52） A bridging immunogenicity assay for monoclonal antibody: case study with SHR-1222, BIOANALYSIS, 2018, 第 3 作者
（53） Predominant contributions of carboxylesterase 1 and 2 in hydrolysis of anordrin in humans, XENOBIOTICA, 2018, 第 2 作者
（54） LC-MS/MS法测定大鼠血浆中黄酮醇糖苷及其主要代谢物, Simultaneous determination of flavonol glycoside and its major metabolites by LC-MS/MS in rat plasma, 药学学报, 2018, 第 4 作者
（55） 肝脏和肠道酯酶在药物代谢及新药研发中的作用, Role of human liver and intestine esterases in drug design and development, 药学学报, 2018, 第 3 作者
（56） 液相色谱-串联质谱生物分析方法的基质效应和对策, Matrix Effects and Countermeasure of Liquid Chromatography-Tandem Mass Spectrometry in Bioanalysis, 质谱学报, 2017, 第 2 作者
（57） Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer, EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 第 7 作者
（58） Bioequivalence of generic alendronate sodium tablets (70 mg) to Fosamax (R) tablets (70 mg) in fasting, healthy volunteers: a randomized, open-label, three-way, reference-replicated crossover study, DRUG DESIGN DEVELOPMENT AND THERAPY, 2017, 第 2 作者
（59） Nimesulide and 4 '-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis, DRUG METABOLISM AND DISPOSITION, 2017, 通讯作者
（60） LC-MS/MS法同时测定人血浆中AST2818和去甲基代谢物, 2017, 第 4 作者
（61） 罗汉果醇在大鼠血浆中代谢产物鉴定及药代动力学研究, 药学学报, 2017, 第 5 作者
（62） 非p450酶介导的药物氧化代谢研究进展, 药学学报, 2017, 第 3 作者
（63） Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution, ONCOTARGET, 2017, 第 19 作者
（64） LC-MS/MS法同时测定人血浆中多纳非尼及其N-氧化代谢物, 药学学报, 2017, 第 5 作者
（65） Arylacetamide Deacetylase Is Involved in Vicagrel Bioactivation in Humans, FRONTIERS IN PHARMACOLOGY, 2017, 第 2 作者
（66） Discovery of Novel Pyridone-Conjugated Monosulfactams as Potent and Broad-Spectrum Antibiotics for Multidrug-Resistant Gram-Negative Infections, JOURNALOFMEDICINALCHEMISTRY, 2017, 第 10 作者
（67） Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: A Combined Computational and Experimental Study, JOURNAL OF MEDICINAL CHEMISTRY, 2017, 通讯作者
（68） Safety, Pharmacokinetics and Pharmacodynamics of Hetrombopag Olamine, a Novel TPO-R Agonist, in Healthy Individuals, BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2017, 第 6 作者
（69） Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials, CANCER LETTERS, 2017, 第 18 作者
（70） Population Pharmacokinetic and Covariate Analysis of Apatinib, an Oral Tyrosine Kinase Inhibitor, in Healthy Volunteers and Patients with Solid Tumors, CLINICAL PHARMACOKINETICS, 2017, 第 6 作者
（71） 液相色谱-质谱联用技术在药物代谢产物鉴定中的应用, Applications of Liquid Chromatography-Mass Spectrometry in Drug Metabolite Identification, 质谱学报, 2017, 第 2 作者
（72） Metabolism and pharmacokinetics of vicagrel, a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy Chinese subjects, DRUG METABOLISM AND PHARMACOKINETICS, 2017, 第 2 作者
（73） Aberrant intracellular metabolism of T‐ DM 1 confers T‐ DM 1 resistance in human epidermal growth factor receptor 2‐positive gastric cancer cells, CANCER SCIENCE, 2017, 第 5 作者
（74） Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins, DRUG METABOLISM AND DISPOSITION, 2017, 通讯作者
（75） Uremic toxins likely boost the plasma exposure of morinidazole conjugated metabolites in the renal failure patients, DRUG METABOLISM AND PHARMACOKINETICS, 2017, 第 7 作者
（76） LC-MS/MS法测定犬血浆中他喷他多并评价结合型代谢物对测定的影响, 药学学报, 2016, 第 6 作者
（77） Wedelolactone metabolism in rats through regioselective glucuronidation catalyzed by uridine diphosphate-glucuronosyltransferases 1As (UGT1As), PHYTOMEDICINE, 2016, 通讯作者
（78） Characterization of TPN729 metabolites in humans using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2016, 第 4 作者
（79） 抗体偶联药物研发中的生物分析, 药学学报, 2016, 第 2 作者
（80） 9-Glucathionyl-6,7-dihydroxymethyl-5H- pyrrolizine is the major pyrrolic glutathione conjugate of retronecine-type pyrrolizidine alkaloids in liver microsomes and in rats, Chemical Research in Toxicology, 2016, 通讯作者
（81） Effect of N -methyl deuteration on metabolism and pharmacokinetics of enzalutamide, DRUG DESIGN DEVELOPMENT AND THERAPY, 2016, 第 6 作者
（82） Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 第 7 作者
（83） 紫杉醇不同剂型对大鼠血浆中游离药物浓度的影响, 中国医药工业杂志, 2016, 第 5 作者
（84） Solid-state characterization of 17 beta-estradiol co-crystals presenting improved dissolution and bioavailability, CRYSTENGCOMM, 2016, 通讯作者
（85） 犬血浆中泮托拉唑对映异构体的纤维素手性色谱柱LC-MS/MS法测定, 中国医药工业杂志, 2016, 第 3 作者
（86） 我国研发的小分子酪氨酸激酶抑制剂的药物代谢研究, 药学学报, 2016, 第 2 作者
（87） Effect of N -methyl deuteration on metabolism and pharmacokinetics of enzalutamide, DRUG DESIGN DEVELOPMENT AND THERAPY, 2016, 第 6 作者
（88） Analysis of diacylglycerols by ultra performance liquid chromatography-quadrupole time-of-flight mass spectrometry: Double bond location and isomers separation, ANALYTICA CHIMICA ACTA, 2016, 通讯作者
（89） 9-Glutathiony1-6,7-dihydro-1-hydroxymethy1-5H-pyrrolizine Is the Major Pyrrolic Glutathione Conjugate of Retronecine-Type Pyrrolizidine Alkaloids in Liver Microsomes and in Rats, CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 通讯作者
（90） LC-MS/MS法测定人血浆中的安纳拉唑及药动学初步应用, Determination of anaprazole in human plasma by LC-MS/MS in pharmacokinetic study, 药学学报, 2016, 第 8 作者
（91） Effects of probenecid and cimetidine on the pharmacokinetics of nemonoxacin in healthy Chinese volunteers, DRUGDESIGNDEVELOPMENTANDTHERAPY, 2016, 第 4 作者
（92） Reducing central serotonin in adulthood promotes hippocampal neurogenesis, SCIENTIFIC REPORTS, 2016, 第11作者
（93） Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes, DRUG METABOLISM AND DISPOSITION, 2015, 通讯作者
（94） High-throughput salting-out-assisted liquid-liquid extraction for the simultaneous determination of atorvastatin, ortho-hydroxyatorvastatin, and para-hydroxyatorvastatin in human plasma using ultrafast liquid chromatography with tandem mass spectrometry, JOURNAL OF SEPARATION SCIENCE, 2015, 通讯作者
（95） 稳定同位素内标对人血浆样品中伊伐布雷定和 N-去甲基伊伐布雷定测定的影响, Effects of stable isotope labeled internal standard on determination of ivabradine and N-demethylivabradine in human plasma, 药学学报, 2015, 第 6 作者
（96） LC-MS／MS法同时测定人血浆中西维来司他及其代谢物, Simultaneous determination of sivelestat and its metabolite XW-IMP-A in human plasma using HPLC-MS/MS, 药学学报, 2015, 第 6 作者
（97） LC-MS/MS法测定干血斑样品中阿戈美拉汀, 药物分析杂志, 2015, 第 3 作者
（98） Simultaneous determination of capecitabine and its three nucleoside metabolites in human plasma by high performance liquid chromatography–tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B, 2015, 第 6 作者
（99） 蛋白质类手性固定相的研究进展及其在药物手性拆分中的应用, 中国医药工业杂志, 2015, 第 2 作者
（100） Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model, ACTA PHARMACOLOGICA SINICA, 2015, 第 7 作者
（101） Simultaneous determination of capecitabine and its three nucleoside metabolites in human plasma by high performance liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2015, 通讯作者
（102） Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury, DRUG METABOLISM AND DISPOSITION, 2015, 通讯作者
（103） Chemical and Enzymatic Transformations of Nimesulide to GSH Conjugates through Reductive and Oxidative Mechanisms, CHEMICAL RESEARCH IN TOXICOLOGY, 2015, 通讯作者
（104） Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel, DRUG METABOLISM AND DISPOSITION, 2015, 第 6 作者
（105） Potential role of organic anion transporting polypeptide 1B1 (OATP1B1) in the selective hepatic uptake of hematoporphyrin monomethyl ether isomers, Potential role of organic anion transporting polypeptide 1B1 (OATP1B1) in the selective hepatic uptake of hematoporphyrin monomethyl ether isomers, ACTA PHARMACOLOGICA SINICA, 2015, 第 4 作者
（106） 人血浆中苯达莫司汀和活性代谢产物γ-羟基苯达莫司汀的LC-MS/MS 法测定, 中国医药工业杂志, 2015, 第 5 作者
（107） On-cartridge derivatization coupled with solid-phase extraction for the ultra-sensitive determination of minodronic acid in human plasma by LC–MS/MS method, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2015, 通讯作者
（108） Determination of ginsenoside compound K in human plasma by liquid chromatography–tandem mass spectrometry of lithium adducts, ACTA PHARMACEUTICA SINICA B, 2015, 第 4 作者
（109） Metabolism of MRX-I, a novel antibacterial oxazolidinone, in humans: the oxidative ring-opening of 2,3-dihydropyrindin-4-one catalyzed by non-P450 enzymes, Drug Metabolism and Disposition, 2015, 通讯作者
（110） 中国男性健康志愿者口服去甲文拉法辛缓释片对映体选择性药动学研究, The enantioselective pharmacokinetic study of desvenlafaxine sustained release tablet in Chinese healthy male volunteers after oral administration, 药学学报, 2015, 第 4 作者
（111） Isomer-selective distribution of 3- n -butylphthalide (NBP) hydroxylated metabolites, 3-hydroxy-NBP and 10-hydroxy-NBP, across the rat blood-brain barrier, ACTA PHARMACOLOGICA SINICA, 2015, 通讯作者
（112） Design, Synthesis, and Biological Evaluation of NovelImidazo1,2- a pyridine Derivatives as Potentc-Met Inhibitors, ACS MEDICINAL CHEMISTRY LETTERS, 2015, 第 10 作者
（113） Effects of an Al 3+ - and Mg 2+ -containing antacid, ferrous sulfate, and calcium carbonate on the absorption of nemonoxacin (TG-873870) in healthy Chinese volunteers, ACTA PHARMACOLOGICA SINICA, 2014, 第 4 作者
（114） Excretion of ~3Htriptolide and its metabolites in rats after oral administration, ACTA PHARMACOLOGICA SINICA, 2014, 第 3 作者
（115） 抗肿瘤新药埃克替尼在动物体内的药动学和组织分布研究, 中国新药杂志, 2014, 第 3 作者
（116） 中国受试者口服茶碱缓释片后尿中原形和代谢物定量分析, 药学学报, 2014, 第 4 作者
（117） A sensitive LC-MS/MS method for quantifying clofarabine triphosphate concentrations in human peripheral blood mononuclear cells, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, 通讯作者
（118） 外排转运体对酪氨酸激酶抑制剂体内处置过程的影响, 国际药学研究杂志, 2014, 第 2 作者
（119） Development and validation of a sensitive LC-MS/MS method for simultaneous quantification of sinotecan and its active metabolite in human blood, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, 第 3 作者
（120） Design, Synthesis, and Structure-Activity Relationship Studies of Novel Thioether Pleuromutilin Derivatives as Potent Antibacterial Agents, JOURNAL OF MEDICINAL CHEMISTRY, 2014, 第 7 作者
（121） Effects of rifampicin and ketoconazole on pharmacokinetics of morinidazole in healthy Chinese subjects., Antimicrobial Agents and Chemotherapy, 2014, 通讯作者
（122） Simultaneous determination of ornidazole and its main metabolites in human plasma by LC-MS/MS: application to a pharmacokinetic study, BIOANALYSIS, 2014, 第 5 作者
（123） Metabolism and Pharmacokinetics of Allitinib in Cancer Patients: The Roles of Cytochrome P450s and Epoxide Hydrolase in its Biotransformation, DRUG METABOLISM AND DISPOSITION, 2014, 第 4 作者
（124） EFFECT OF RENAL IMPAIRMENT ON THE PHARMACOKINETICS OF MORINIDAZOLE: ALTERED UPTAKE TRANSPORTER-MEDIATED RENAL CLEARANCE?, DRUG METABOLISM REVIEWS, 2014, 第 1 作者
（125） Effects of Rifampin and Ketoconazole on Pharmacokinetics of Morinidazole in Healthy Chinese Subjects, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 通讯作者
（126） Development and validation of a sensitive LC-MS/MS method for simultaneous quantification of sinotecan and its active metabolite in human blood, JOURNAL OF CHROMATOGRAPHY B, 2014, 第 3 作者
（127） A sensitive LC–MS/MS method for quantifying clofarabine triphosphate concentrations in human peripheral blood mononuclear cells, JOURNAL OF CHROMATOGRAPHY B, 2014, 第 5 作者
（128） A chiral high-performance liquid chromatography–tandem mass spectrometry method for the stereospecific determination of morinidazole in human plasma, JOURNAL OF CHROMATOGRAPHY B, 2014, 第 5 作者
（129） Enantioselective HPLC determination and pharmacokinetic study of secnidazole enantiomers in rats, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, 第 5 作者
（130） 采用生理药动学模型预测抗肿瘤新药法米替尼在人体中的药动学, Predicting pharmacokinetics of anti-cancer drug, famitinib in human using physiologically based pharmacokinetic model, 药学学报, 2014, 第 3 作者
（131） LC-MS／MS法测定人血浆中γ-氨基丁酸及其药动学初步应用, Determination of γ-aminobutyric acid in human plasma by LC-MS/MS and its preliminary application to a human pharmacokinetic study, 药学学报, 2014, 第 5 作者
（132） Effects of Renal Impairment on the Pharmacokinetics of Morinidazole: Uptake Transporter-Mediated Renal Clearance of the Conjugated Metabolites, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 通讯作者
（133） 生物样品定量分析方法验证中试验样品再分析的意义和对策, 中国药学杂志, 2014, 第 1 作者
（134） Development of a UHPLC–MS/MS method for the determination of plasma histamine in various mammalian species, JOURNAL OF CHROMATOGRAPHY B, 2014, 第 4 作者
（135） Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1, DRUG METABOLISM AND DISPOSITION, 2014, 通讯作者
（136） Identification of Amino Acid and Glutathione N-Conjugates of Toosendanin: Bioactivation of the Furan Ring Mediated by CYP3A4, CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 通讯作者
（137） Enantioselective HPLC determination and pharmacokinetic study of secnidazole enantiomers in rats, JOURNAL OF CHROMATOGRAPHY B, 2014, 第 5 作者
（138） LC-HESI/MS/MS法同时测定人血浆中氨氯地平、贝那普利和贝那普利拉, 药学学报, 2014, 第 4 作者
（139） Development of a UHPLC-MS/MS method for the determination of plasma histamine in various mammalian species, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, 第 4 作者
（140） 奋乃静在人胆汁中的代谢物分析, Analysis of Perphenazine Metabolites in Human Bile, 质谱学报, 2014, 第 4 作者
（141） Design, Synthesis, and Structure-Activity and Structure-Pharmacokinetic Relationship Studies of Novel 6,6,5 Tricyclic Fused Oxazolidinones Leading to the Discovery of a Potent, Selective, and Orally Bioavailable FXa Inhibitor, JOURNAL OF MEDICINAL CHEMISTRY, 2014, 第 10 作者
（142） A chiral high-performance liquid chromatography-tandem mass spectrometry method for the stereospecific determination of morinidazole in human plasma, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, 通讯作者
（143） 醛氧化酶在药物代谢中的作用, The role of aldehyde oxidase in drug metabolism, 宝鸡文理学院学报(自然科学版), 2014, 第 2 作者
（144） Excretion of H-3 triptolide and its metabolites in rats after oral administration, ACTA PHARMACOLOGICA SINICA, 2014, 第 3 作者
（145） Development and validation of a sensitive LC–MS/MS assay for the simultaneous quantification of allitinib and its two metabolites in human plasma, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013, 第 3 作者
（146） Enantioselective determination of 3-n-butylphthalide (NBP) in human plasma by liquid chromatography on a teicoplanin-based chiral column coupled with tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 通讯作者
（147） High-Resolution Mass Spectrometry: An Ideal Analytical Tool for Drug Metabolism Studies, LC GC NORTH AMERICA, 2013, 第 2 作者
（148） Effects of ketoconazole and rifampicin on the pharmacokinetics of GLS4, a novel anti-hepatitis B virus compound, in dogs, ACTA PHARMACOLOGICA SINICA, 2013, 第 4 作者
（149） QUANTIFICATION OF LETROZOLE IN HUMAN PLASMA USING LC-()ESI-MS/MS WITH D-4-LETROZOLE AS INTERNAL STANDARD: APPLICATION IN A PHARMACOKINETIC STUDY, JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2013, 第 3 作者
（150） High-Resolution Mass Spectrometry: An Ideal Premier Analytical Tool for Drug Metabolism Studies, LC GC EUROPE, 2013, 第 2 作者
（151） Simultaneous quantification of 22R and 22S epimers of budesonide in human plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry: Application in a stereoselective pharmacokinetic study, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 第 4 作者
（152） Phase I study of the safety, pharmacokinetics and antitumor activity of famitinib, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 第 4 作者
（153） Stereoselective Glucuronidation of Ornidazole in Humans: Predominant Contribution of UDP-Glucuronosyltransferases 1A9 and 2B7, DRUG METABOLISM AND DISPOSITION, 2013, 第 3 作者
（154） High-sensitivity liquid chromatography-tandem mass spectrometry method for the simultaneous determination of sodium picosulfate and its three major metabolites in human plasma, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 通讯作者
（155） Solubility-Driven Optimization of (Pyridin-3-yl) Benzoxazinyl-oxazolidinones Leading to a Promising Antibacterial Agent, JOURNAL OF MEDICINAL CHEMISTRY, 2013, 第 7 作者
（156） Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of febuxostat in human plasma, BIOMEDICAL CHROMATOGRAPHY, 2013, 第 3 作者
（157） Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation, DRUG METABOLISM AND DISPOSITION, 2013, 通讯作者
（158） Oxidation-sensing Regulator AbfR Regulates Oxidative Stress Responses, Bacterial Aggregation, and Biofilm Formation in Staphylococcus epidermidis, JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 第 7 作者
（159） liquidchromatographytandemmassspectrometrysimultaneousdeterminationofrepaglinideandmetformininhumanplasmaanditsapplicationtobioequivalencestudy, 药学学报, 2013, 第 5 作者
（160） Metabolism and Pharmacokinetics of Novel Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitor Apatinib in Humans, DRUG METABOLISM AND DISPOSITION, 2013, 第 2 作者
（161） 柱前衍生化LC-MS/MS法同时测定人血浆中厄多司坦及其活性代谢物, 药学学报, 2013, 第 2 作者
（162） Discovery and Mechanism Study of SIRT1 Activators that Promote the Deacetylation of Fluorophore-Labeled Substrate, JOURNAL OF MEDICINAL CHEMISTRY, 2013, 第 10 作者
（163） Metabolite profiling and identification of triptolide in rats, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 第 4 作者
（164） Characterization of metabolites of GLS4 in humans using ultrahigh-performance liquid chromatography/quadrupole time-of-flight mass spectrometry, RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2013, 第 4 作者
（165） Pharmacokinetics, Metabolism, and Excretion of the Antiviral Drug Arbidol in Humans, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 通讯作者
（166） Discovery and Mechanism Study of SIRT1 Activators that Promote the Deacetylation of Fluorophore-Labeled Substrate, JOURNAL OF MEDICINAL CHEMISTRY, 2013, 第 10 作者
（167） A fragmentation-based method for the differentiation of glutathione conjugates by high-resolution mass spectrometry with electrospray ionization, ANALYTICA CHIMICA ACTA, 2013, 通讯作者
（168） Enantioselective determination of ornidazole in human plasma by liquid chromatography–tandem mass spectrometry on a Chiral-AGP column, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013, 第 5 作者
（169） Simultaneous quantitation of 3-n-butylphthalide (NBP) and its four major metabolites in human plasma by LC–MS/MS using deuterated internal standards, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013, 通讯作者
（170） 亲水作用色谱串联质谱法测定气雾剂给药后人血浆中的沙丁胺醇, 药物分析杂志, 2013, 第 2 作者
（171） Metabolite profiling and identification of triptolide in rats, JOURNAL OF CHROMATOGRAPHY B, 2013, 第 4 作者
（172） Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients, BRITISH JOURNAL OF PHARMACOLOGY, 2013, 通讯作者
（173） 阿帕替尼在人体内的代谢、排泄和药动学研究, 2012, 第 2 作者
（174） 中药注射剂成分绿原酸和鱼腥草素代谢活化机理研究, 2012, 第 1 作者
（175） 微生物转化法从雷公藤甲素合成雷腾舒, Biotransformation of triptolide to ( 5R ) -5-hydroxytriptolide, 中国新药杂志, 2012, 第 3 作者
（176） 中国健康志愿者单次和多次口服阿德福韦酯片的药动学, Pharmacokinetics of Adefovir Dipivoxil Tablets in Chinese Healthy Subjects, 中国药学杂志, 2012, 第 6 作者
（177） Identification of the ortho-Benzoquinone Intermediate of 5-O-Caffeoylquinic Acid In Vitro and In Vivo: Comparison of Bioactivation under Normal and Pathological Situations, DRUG METABOLISM AND DISPOSITION, 2012, 通讯作者
（178） 鱼腥草素钠对BALB/c小鼠的急性毒性及其对细胞的损伤, 中国药理学与毒理学杂志, 2012, 第 4 作者
（179） 对映体选择性LC-MS／MS法测定人血浆中R／S-华法林及其在药物相互作用研究中的应用, Enantioselective determinination of R-warfarin/S-warfarin in human plasma using liquid chromatography-tandem mass spectrometry and its application in a drug-drug interaction study, 药学学报, 2012, 第 3 作者
（180） 转运体在药物经肝脏清除过程中的作用, Role of transporters in hepatic drug disposition, 药学学报, 2012, 第 2 作者
（181） Simultaneous determination of flumatinib and its two major metabolites in plasma of chronic myelogenous leukemia patients by liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 通讯作者
（182） 奥硝唑在人体内的代谢与排泄研究, 2012, 第 3 作者
（183） Derivatization methods for quantitative bioanalysis by LC-MS/MS, BIOANALYSIS, 2012, 第 3 作者
（184） Development and validation of a sensitive LC-MS/MS assay for simultaneous quantitation of ranolazine and its three metabolites in human plasma, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 第 2 作者
（185） Metabolism and Pharmacokinetics of Morinidazole in Humans: Identification of Diastereoisomeric Morpholine N+-Glucuronides Catalyzed by UDP Glucuronosyltransferase 1A9, DRUG METABOLISM AND DISPOSITION, 2012, 通讯作者
（186） Mechanistic Studies on the Absorption and Disposition of Scutellarin in Humans: Selective OATP2B1-Mediated Hepatic Uptake Is a Likely Key Determinant for Its Unique Pharmacokinetic Characteristics, DRUG METABOLISM AND DISPOSITION, 2012, 第 5 作者
（187） 正负离子切换液相色谱-串联质谱法同时测定人血浆中头孢他啶和他唑巴坦, Simultaneous determination of ceftazidime and tazobactam in human plasma with sequential positive and negative ionization liquid chromatography- tandem mass spectrometric detection, 药物分析杂志, 2012, 第 2 作者
（188） In Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9, DRUG METABOLISM AND DISPOSITION, 2012, 第 2 作者
（189） CYP3A-mediated apoptosis of dauricine in cultured human bronchial epithelial cells and in lungs of CD-1 mice, TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 第 3 作者
（190） Validation of a chiral liquid chromatography-tandem mass spectrometry method for the determination of pantoprazole in dog plasma, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 通讯作者
（191） Simultaneous determination of apatinib and its four major metabolites in human plasma using liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 第 2 作者
（192） A continued saga of Boc5, the first non-peptidic glucagon-like peptide-1 receptor agonist with in vivo activities, ACTA PHARMACOLOGICA SINICA, 2012, 第 10 作者
（193） Simultaneous determination of morinidazole, its N-oxide, sulfate, and diastereoisomeric N+-glucuronides in human plasma by liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 通讯作者
（194） Trimethylsilyldiazomethane derivatization coupled with solid-phase extraction for the determination of alendronate in human plasma by LC-MS/MS, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2012, 通讯作者
（195） Recent advances in metabolite identification and quantitative bioanalysis by LC-Q-TOF MS, BIOANALYSIS, 2012, 通讯作者
（196） Identification of modification sites on human serum albumin and human hemoglobin adducts with houttuynin using liquid chromatography coupled with mass spectrometry, BIOMEDICAL CHROMATOGRAPHY, 2012, 通讯作者
（197） Covalent protein binding and tissue distribution of houttuynin in rats after intravenous administration of sodium houttuyfonate, ACTA PHARMACOLOGICA SINICA, 2012, 通讯作者
（198） 鉴定大鼠注射绿原酸后体内的代谢产物, Metabolites of injected chlorogenic acid in rats, 药学学报, 2011, 第 3 作者
（199） 液相色谱-紫外光谱-离子阱质谱法分析灰黄霉素中的相关杂质, LC-UV/MS~n analysis of related impurities of griseofulvin, 药物分析杂志, 2011, 第 5 作者
（200） 液相色谱-串联质谱法测定人血浆中雷洛昔芬及其在制剂生物等效性研究中的应用, Determination of raloxifene in human plasma using liquid chromatography tandem mass spectrometry and its application in bioequivalence study, 中国新药杂志, 2011, 第 3 作者
（201） Cardio-Protection of Salvianolic Acid B through Inhibition of Apoptosis Network, PLOS ONE, 2011, 第 5 作者
（202） 高灵敏度液相色谱-串联质谱法测定人血浆中普拉克索, LC-MS/MS determination of pramipexole in human plasma, 药物分析杂志, 2011, 第 2 作者
（203） Identification of Amiodarone Metabolites in Human Bile by Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry, DRUG METABOLISM AND DISPOSITION, 2011, 第 3 作者
（204） Identification of 20(S)-Protopanaxadiol Metabolites in Human Liver Microsomes and Human Hepatocytes, DRUG METABOLISM AND DISPOSITION, 2011, 第 2 作者
（205） LC／MS技术在寡核苷酸类药物生物样品定量分析和代谢物鉴定中的应用, Quantitative Analysis and Metabolite Identification of Therapeutic Oligonucleotides in Biological Samples Using LC/MS, 质谱学报, 2011, 第 3 作者
（206） Quantifying tetrapeptide SS-20 in rat plasma using hydrophilic interaction liquid chromatography coupled with electrospray ionization tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2011, 第 2 作者
（207） Investigation of Isomeric Transformations of Chlorogenic Acid in Buffers and Biological Matrixes by Ultraperformance Liquid Chromatography Coupled with Hybrid Quadrupole/Ion Mobility/Orthogonal Acceleration Time-of-Flight Mass Spectrometry, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2011, 通讯作者
（208） 己糖激酶法间接测定人血浆和尿样中的羟乙基淀粉浓度及药动学应用, Indirect Determination of Hydroxyethyl Starch in Human Plasma and Urine by Hexokinase Method and Its Application in Pharmacokinetic Study, 中国药学杂志, 2011, 第 4 作者
（209） 氟西汀及其活性代谢产物在汉族健康人体的药动学, Pharmacokinetic study of fluoxetine and its active metabolite in healthy Han Chinese volunteers, 中国医院药学杂志, 2011, 第 4 作者
（210） 亲水作用色谱串联质谱法测定人血浆中的拉米夫定, Determination of lamivudine in human plasma by hydrophilic interaction chromatography (HILIC) tandem mass spectrometry, 药物分析杂志, 2011, 第 3 作者
（211） UPLC/Q-TOFMS法研究吗啉硝唑人体内外代谢, 2011, 第 6 作者
（212） UPLC/Q-TOFMS法检测和鉴定阿帕替尼在肿瘤患者血浆和尿中代谢产物, 2011, 第 2 作者
（213） Pulmonary Toxicity and Metabolic Activation of Tetrandrine in CD-1 Mice, CHEMICAL RESEARCH IN TOXICOLOGY, 2011, 通讯作者
（214） Absorption and Disposition of Scutellarin in Rats: A Pharmacokinetic Explanation for the High Exposure of Its Isomeric Metabolite, DRUG METABOLISM AND DISPOSITION, 2011, 第 2 作者
（215） 液相色谱-串联质谱法检测反应性代谢物, Applications of Liquid Chromatography-Tandem Mass Spectrometry to Detection and Characterization of Reactive Metabolites, 质谱学报, 2011, 第 3 作者
（216） 比较他克莫司缓释制剂与普通制剂在中国肾移植患者的药代动力学, Comparison the pharmacokinetics of tacrolimus in Chinese kidney transplant patients after repeated-dose of modified release and immediate release preparations, 中国临床药理学杂志, 2011, 第 2 作者
（217） 液相色谱串联质谱法同时测定人血浆中雷诺嗪及其三种代谢产物, 2011, 第 2 作者
（218） 犬血浆中决奈达隆及其代谢物SR35021的LC-MS/MS法测定, 中国医药工业杂志, 2011, 第 5 作者
（219） Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2011, 通讯作者
（220） Derivatization of (5 R)-hydroxytriptolide from benzylamine to enhance mass spectrometric detection: Application to a Phase I pharmacokinetic study in humans, ANALYTICA CHIMICA ACTA, 2011, 第 2 作者
（221） Pharmacokinetics of tacrolimus converted from twice-daily formulation to once-daily formulation in Chinese stable liver transplant recipients, ACTA PHARMACOLOGICA SINICA, 2011, 第 2 作者
（222） 液相色谱-串联质谱法测定人血浆中替扎尼定, LC-MS/MS determination of tizanidine in human plasma, 药物分析杂志, 2011, 第 3 作者
（223） Quantification of the major metabolites of bromhexine in human plasma using RRLC–MS/MS and its application to pharmacokinetics, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2010, 第 2 作者
（224） The effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of glipizide in Chinese subjects, EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2010, 第 3 作者
（225） Enantioselective determination of doxazosin in human plasma by liquid chromatography-tandem mass spectrometry using ovomucoid chiral stationary phase, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2010, 通讯作者
（226） Evidence for the Bioactivation of 4-Nonylphenol to Quinone Methide and ortho-Benzoquinone Metabolites in Human Liver Microsomes, CHEMICAL RESEARCH IN TOXICOLOGY, 2010, 通讯作者
（227） Metabolic Activation of Chlorogenic Acid in vitro and in vivo, DRUG METABOLISM REVIEWS, 2010, 第 1 作者
（228） Determination of tegafur, 5-fluorouracil, gimeracil and oxonic acid in human plasma using liquid chromatography–tandem mass spectrometry, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2010, 通讯作者
（229） Determination of picamilon concentration in human plasma by liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2010, 第 2 作者
（230） 替吉奥胶囊（S-1）在中国癌症患者体内的药代动力学和生物等效性, Pharmacokinetics and bioequivalence of S -1 capsules in Chinese patients with cancer, 中国临床药理学杂志, 2010, 第 2 作者
（231） 液相色谱-串联质谱法测定人血浆中环酯红霉素, Determination of Erythromycin Cyclic 11,12-Carbonate in Human Plasma by LC-MS/MS Method, 中国药学杂志, 2010, 第 2 作者
（232） Bioanalysis of an oligonucleotide and its metabolites by liquid chromatography–tandem mass spectrometry, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2010, 第 2 作者
（233） 米索前列醇片不同给药途径的人体药动学研究, Pharmacokinetic Studies of Misoprostol Tablet Following Oral,Sublingual and Vaginal Administration in Female Volunteers, 中国药学杂志, 2010, 第 3 作者
（234） Metabolism of Flumatinib, a Novel Antineoplastic Tyrosine Kinase Inhibitor, in Chronic Myelogenous Leukemia Patients, DRUG METABOLISM AND DISPOSITION, 2010, 第 2 作者
（235） LC-MS/MS法测定人血浆中的辅酶Q10, LC-MS/MS determination of coenzyme Q10 in human plasma, 药物分析杂志, 2010, 第 4 作者
（236） 液-质联用法测定人血浆中磷霉素的浓度及其应用, The method for determination of fosfomycin in human plasma by LC-MS/MS and its application, 中国医院药学杂志, 2010, 第 6 作者
（237） 绿原酸和双黄连粉针剂致敏性比较评价, Allergenicity Assessment and Comparison between Chlorogenic Acid and Shuanghuanglian Fenzhenji, 世界科学技术(中医药现代化), 2010, 第 6 作者
（238） Chronic Morphine Treatment Impaired Hippocampal Long-Term Potentiation and Spatial Memory via Accumulation of Extracellular Adenosine Acting on Adenosine A 1 Receptors, JOURNAL OF NEUROSCIENCE, 2010, 第11作者
（239） Pulmonary Toxicity and Metabolic Activation of Dauricine in CD-1 Mice, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2010, 第 3 作者
（240） Determination of arotinoid acid in human plasma by liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2009, 第 2 作者
（241） Determination of tropisetron in human plasma by liquid chromatography-tandem mass spectrometry, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2009, 通讯作者
（242） Rapid and sensitive liquid chromatography-tandem mass spectrometry method for the determination of leuprolide in human serum, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2009, 第 2 作者
（243） Design, synthesis and evaluation of novel oxazaphosphorine prodrugs of 9-(2-phosphonomethoxyethyl)adenine (PMEA, adefovir) as potent HBV inhibitors, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 第 4 作者
（244） Pharmacokinetic studies of meloxicam following oral and transdermal administration in Beagle dogs, ACTA PHARMACOLOGICA SINICA, 2009, 第 2 作者
（245） 鱼腥草素与人血清白蛋白的共价结合研究, 2009, 第 3 作者
（246） Metabolic Profiling of 3H20(S)-Protopanaxadiol in Rat Bile, DRUG METABOLISM REVIEWS, 2009, 第 3 作者
（247） Liquid chromatography/tandem mass spectrometry method for the quantification of deserpidine in human plasma: Application to a pharmacokinetic study, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2009, 通讯作者
（248） Synthesis of 3-H-320(S)-protopanaxadiol, JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2009, 第 4 作者
（249） 参与20（S）-原人参二醇代谢的细胞色素P450亚型, 2009, 第 2 作者
（250） 健康受试者口服复方替米沙坦片后替米沙坦的药动学研究, Study on Pharmacokinetics of Compound Telmisartan Tablets in Chinese Healthy Volunteers, 苏州大学学报医学版, 2009, 第 4 作者
（251） Identification of Quinone Methide Metabolites of Dauricine in Human Liver Microsomes and in Rat Bile, CHEMICAL RESEARCH IN TOXICOLOGY, 2009, 通讯作者
（252） Determination of eptifibatide concentration in human plasma utilizing the liquid chromatography-tandem mass spectrometry method, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2009, 第 3 作者
（253） 液相色谱-串联质谱法测定人血浆中的尼索地平, LC -MS/MS determination of nisoldipine in human plasma, 药物分析杂志, 2009, 第 3 作者
（254） Simultaneous determination of 6R-leucovorin, 6S-leucovorin and 5-methyltetrahydrofolate in human plasma using solid phase extraction and chiral liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2009, 通讯作者
（255） The metabolism of CYP2C9 and CYP2C19 for gliclazide by homology modeling and docking study, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 第 6 作者
（256） 灯盏乙素口服吸收机制的研究, 2009, 第 3 作者
（257） 多沙唑嗪人体内药动学和肝微粒体中代谢的立体选择性研究, 2009, 第 5 作者
（258） Characterization of Houttuynin Adducts with Phenylalanine and Lysine in Insulin B Chain, DRUG METABOLISM REVIEWS, 2009, 第 2 作者
（259） 人胆汁中胺碘酮代谢产物的研究, 2009, 第 6 作者
（260） 一种寡核苷酸及其代谢物的液相色谱-串联质谱生物样品分析, 2009, 第 2 作者
（261） 酪氨酸激酶抑制剂抗肿瘤新药氟马替尼在人体内的代谢产物研究, 2009, 第 2 作者
（262） 小檗胺人肝微粒体及大鼠胆汁中反应性代谢物研究, 2009, 第 3 作者
（263） 快速鉴定4-壬基苯酚在人和大鼠肝微粒体中的反应性代谢物, 2009, 第 1 作者
（264） Enantioselective quantification of chiral drugs in human plasma with LC-MS/MS, BIOANALYSIS, 2009, 通讯作者
（265） Quantification of polar drugs in human plasma with liquid chromatography-tandem mass spectrometry, BIOANALYSIS, 2009, 第 2 作者
（266） Characterization of metabolites of a novel histamine H-2-receptor antagonist, lafutidine, in human liver microsomes by liquid chromatography coupled with ion trap mass spectrometry, RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2008, 第 2 作者
（267） 液相色谱-串联质谱法测定家兔血浆中倍他米松, Liquid chromatography/tandem mass spectrometry in determination of betamethasone concentration in rabbit plasma, 第二军医大学学报, 2008, 第 2 作者
（268） STEREOSELECTIVE PHARMACOKINETICS OF ONDANSETRON IN HUMANS: ROLE OF PLASMA PROTEIN BINDING, DRUG METABOLISM REVIEWS, 2008, 第 4 作者
（269） LC/MS/MS法测定比格犬血浆中埃克替尼及其在药动学研究中的应用, Pharmacokinetics of icotinib in Beagle dog studied by using LC/MS/MS method, 中国临床药理学与治疗学, 2008, 第 2 作者
（270） STEREOSELECTIVE METABOLISM OF ONDANSETRON BY HUMAN CYTOCHROME P450 ENZYMES, DRUG METABOLISM REVIEWS, 2008, 第 2 作者
（271） Metabolite identification of a new antitumor agent icotinib in rats using liquid chromatography/tandem mass spectrometry, RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2008, 第 2 作者
（272） METABOLISM OF ICOTINIB, AN EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR, IN RAT, DRUG METABOLISM REVIEWS, 2008, 第 1 作者
（273） HPLC-MS／MS法测定人血浆中的左西孟旦及其主要代谢物, Determination of levosimendan and its main metabolites in human plasma with HPLC-MS/MS method, 药学学报, 2008, 第 2 作者
（274） Validated LC-MS/MS method for quantitative determination of rasagiline in human plasma and its application to a pharmacokinetic study, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2008, 第 2 作者
（275） EFFECT OF CYP2D6*10 ALLELE ON THE PHARMACOKINETICS OF CHLORPHENIRAMINE IN CHINESE SUBJECTS, DRUG METABOLISM REVIEWS, 2008, 第 4 作者
（276） 液相色谱-串联质谱法测定犬血浆中布地奈德, LC-MS/MS determination of budesonide in dog plasma, 药学学报, 2008, 第 3 作者
（277） P450-MEDIATED METABOLIC ACTIVATION OF DAURICINE: IDENTIFICATION OF GLUTATHIONE CONJUGATES IN HUMAN LIVER MICROSOMES AND IN RATS, DRUG METABOLISM REVIEWS, 2008, 第 2 作者
（278） 吲达帕胺缓释胶囊人体药动学和生物等效性试验, Pharmacokinetics and bioequivalence study of indapamide sustained-release capsules in human whole blood, 中国医院药学杂志, 2008, 第 4 作者
（279） 利巴韦林含片的人体药动学及生物等效性研究, Bioequivalence and pharmacokinetics of ribavirin buccal tablets in healthy volunteers, 中国临床药理学与治疗学, 2008, 第 2 作者
（280） Metabolite identification of arbidol in human urine by the study of CID fragmentation pathways using HPLC coupled with ion trap mass spectrometry, JOURNAL OF MASS SPECTROMETRY, 2008, 第 2 作者
（281） PHARMACOKINETICS OF CARISOPRODOL AT TWO DOSAGE LEVELS AND INFLUENCE OF CYP2C19 POLYMORPHISM ON ITS PHARMACOKINETICS IN HEALTHY CHINESE VOLUNTEERS, DRUG METABOLISM REVIEWS, 2008, 第 3 作者
（282） PHARMACOKINETICS STUDY OF GIMERACIL, TEGAFUR AND 5-FLUOROURACIL IN CHINESE CANCER PATIENTS AFTER SINGLE AND MULTIPLE DOSES, DRUG METABOLISM REVIEWS, 2008, 第 3 作者
（283） Quantitative determination of ondansetron in human plasma by enantioselective liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2008, 通讯作者
（284） Bioavailability of clarithromycin cyclodextrin ternary complexes upon oral administration to healthy beagle dogs, DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2008, 第 4 作者
（285） 液相色谱-串联质谱法快速测定人血浆中布洛芬, Rapid Determination of Ibuprofen in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry Method, 中国药学杂志, 2008, 第 5 作者
（286） IDENTIFICATION OF SOME UNCOMMON PATHWAYS IN DRUG METABOLISM WITH LC/MS/MS, DRUG METABOLISM REVIEWS, 2008, 第 2 作者
（287） 枸橼酸他莫昔芬胶囊的人体生物等效性, Bioequivalence of tamoxifen citrate capsules in healthy volunteers, 中国医院药学杂志, 2008, 第 4 作者
（288） 反相离子对高效液相色谱法测定人血浆中羟苯磺酸, RP -HPLC determination of dobesilic acid in human plasma, 药物分析杂志, 2007, 第 2 作者
（289） Rapid and selective liquid chromatographic/tandem mass spectrometric method for the determination of fosfomycin in human plasma, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 第 2 作者
（290） Quantification of Erdosteine in the Low-volume of Dog Plasma by Liquid Chromatography Tandem Mass Spectrometry, Quantification of Erdosteine in the Low-volume of Dog Plasma by Liquid Chromatography Tandem Mass Spectrometry, 高等学校化学研究：英文版, 2007, 第 4 作者
（291） Liquid chromatography/negative ion electrospray tandem mass spectrometry method for the quantification of rosuvastatin in human plasma: Application to a pharmacokinetic study, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 通讯作者
（292） 反式白藜芦醇葡糖苷在大鼠组织中的体外代谢研究, Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues, 药学学报, 2007, 第 2 作者
（293） LC／MS／MS法测定中国健康志愿者血浆中瑞舒伐他汀浓度及药动学, Determination of Rosuvastatin in Human Plasma by LC/MS/MS and Study of Pharmacokinetics, 解放军药学学报, 2007, 第 5 作者
（294） 液相色谱-串联质谱法测定人血浆中格列本脲, LC -MS/MS determination of glyburide in human plasma, 药物分析杂志, 2007, 第 3 作者
（295） 液相色谱-串联质谱法测定人血浆中厄贝沙坦, Determination of Irbesartan in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry, 中国医疗前沿, 2007, 第 2 作者
（296） Validated method for rapid inhibition screening of six cytochrome P450 enzymes by liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 第 2 作者
（297） Simultaneous determination of amodiaquine and its active metabolite in human blood by ion-pair liquid chromatography-tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 第 1 作者
（298） 液相色谱-串联质谱法测定人血浆中厄贝沙坦, Determination of Irbesartan in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry, 中国药学杂志, 2007, 第 2 作者
（299） 采用正负离子切换LC-MS/MS法同时测定人血浆中对乙酰氨基酚和水杨酸, 2007, 第 2 作者
（300） COUPLING OF CONJUGATING ENZYMES AND EFFLUX TRANSPORTERS: IMPACT ON THE METABOLISM AND DISPOSITION OF SCUTELLARIN, DRUG METABOLISM REVIEWS, 2007, 第 3 作者
（301） 液相色谱-串联质谱法快速测定人血浆中伊曲康唑, LC- MS/MS determination of itraconazole in human plasma, 药物分析杂志, 2007, 第 2 作者
（302） The effect of Madopar on the pharmacokinetics of ropinirole in healthy Chinese volunteers, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2007, 第 5 作者
（303） 卡立普多在中国人体内的药动学及CYP2C19遗传多态性对其药动学的影响, 2007, 第 2 作者
（304） Precolumn derivatization of cysteine residues for quantitative analysis of five major cytochrome P450 isoenzymes by liquid chromatography/tandem mass spectrometry, RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2007, 第 2 作者
（305） LC-MS／MS法测定人血浆中西酞普兰及其在制剂生物等效性中的应用, Determination of citalopram in human plasma with LC-MS/MS method and its bioequivalent evaluation, 药学学报, 2007, 第 2 作者
（306） Determination of misoprostol acid in human plasma by liquid chromatography coupled to tandem mass spectrometry, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 第 2 作者
（307） Application of a sensitive liquid chromatographic/tandem mass spectrometric method to pharmacokinetic study of nalmefene in humans, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 第 2 作者
（308） Determination of meloxicam in human plasma by liquid chromatography-tandem mass spectrometry following transdermal administration, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 第 2 作者
（309） 一种新软件方法用于单位分辨质谱仪上药物相对分子质量的准确测定, A new software method for accurate mass measurements of drugs on unit mass resolution mass spectrometer, 药学学报, 2007, 第 4 作者
（310） Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 第 2 作者
（311） Improved and simplified liquid chromatography/electrospray ionization mass spectrometry method for the analysis of underivatized glucosamine in human plasma, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 通讯作者
（312） Quantification of erdosteine in the low-volume of dog plasma by liquid chromatography tandem mass spectrometry, CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2007, 第 4 作者
（313） 液液萃取-液相色谱-串联质谱法测定蜂蜜中氯霉素, Determination of Chloramphenicol Residue in Honey by Liquid-Liquid Extraction-Liquid Chromatography-Tandem Mass Spectrometry, 中国食品卫生杂志, 2007, 第 4 作者
（314） LC-MS／MS法测定人血浆中替加色罗的浓度及其在生物等效性研究中的应用, Determination of tegaserod in human plasma by liquid chromatography- tandem mass spectrometry and its application to bioequivalence study, 中国新药杂志, 2007, 第 2 作者
（315） 液相色谱-串联电喷雾离子阱质谱鉴定阿比朵尔的代谢物, 2007, 第 2 作者
（316） LC-MS／MS法测定人血浆中的氨溴索和克仑特罗, Determination of ambroxol and clenbuterol in human plasma by LC-MS/MS method, 药学学报, 2007, 第 2 作者
（317） 液相色谱-串联质谱法测定人血浆中匹伐他汀, Determination of pitavastatin in human plasma by liquid chromatographytandem mass spectrometry, 中国新药与临床杂志, 2007, 第 2 作者
（318） The cytochrome P450 inhibition and induction study of a new anti-inflammatory drug candidate IMM018, DRUG METABOLISM REVIEWS, 2006, 第 3 作者
（319） 测定人血浆中齐多夫定的液相色谱-串联质谱法及生物等效性的应用, Determination of zidovudine in human plasma with LC/MS/MS method and application to a bioequivalence study, 中国新药与临床杂志, 2006, 第 2 作者
（320） 三种替米沙坦制剂在中国健康人体的药动学及生物等效性, 中国新药杂志, 2006, 第 3 作者
（321） 液相色谱串联质谱法测定人血浆中罗格列酮, 中国新药与临床杂志, 2006, 第 2 作者
（322） 手性固定相色谱法直接拆分曲美布汀、拉呋替丁昂丹司琼对映异构体, 药物分析杂志, 2006, 第 2 作者
（323） 液相色谱-串联质谱法测定人血浆中的米氮平及在药动学中的应用, Determination of mirtazapine in human plasma with LC/MS/MS method and application in pharmacokinetic study, 中国新药与临床杂志, 2006, 第 2 作者
（324） 高灵敏度LC/MS/MS法同时测定人血浆中麻黄碱和氯苯那敏, Simultaneous determination of ephedrine and chlorpheniramine in human plasma by a highly sensitive liquid chromatography-tandem mass spectrometric method, 药学学报, 2006, 第 2 作者
（325） 复方法莫替丁咀嚼片的人体药动学, Pharmacokinetics of compound famotidine chewable tabletsin Chinese healthy volunteers, 中国医院药学杂志, 2006, 第 3 作者
（326） 液相色谱-串联质谱法测定人血浆中氟桂利嗪, 中国药学杂志, 2006, 第 2 作者
（327） 液相色谱-串联质谱法测定人血浆中的利培酮, Determination of risperidone in human plasma by liquid chromatography-tandem mass spectrometry, 药学学报, 2006, 第 2 作者
（328） 氟喹诺酮类化合物的电喷雾离子阱质谱分析, Analysis of Fluroquinolones by Electrospray Ion Trap Mass Spectrometry, 质谱学报, 2006, 第 3 作者
（329） 液相色谱-串联质谱法同时测定人血浆中金刚烷胺和氯苯那敏, Simultaneous determination of amantadine and chlorpheniramine in human plasma by liquid chromatography- tandem mass spectrometry, 药物分析杂志, 2006, 第 2 作者
（330） The CYP inhibition study of 20(S)-Protopanaxadiol and ginsenoside Rh2 using recombinant CYP1A2, 2C9, 2D6, and 3A4, DRUG METABOLISM REVIEWS, 2006, 第 4 作者
（331） Metabolite identification of 20(S)-protopanaxadiol in Wistar rats, DRUG METABOLISM REVIEWS, 2006, 第 2 作者
（332） 液相色谱-串联质谱法测定苯妥英在健康人体的血药浓度并研究其生物等效性, Determination the concentration of phenytoin in healthy human plasma and study on its bioequivalence by LC/MS/MS, 中国临床药理学杂志, 2006, 第 2 作者
（333） 血浆中去羟肌苷测定与制剂生物等效性评价, 中国药学杂志, 2006, 第 2 作者
（334） Assignments of H-1 and C-13 NMR spectral data for ondansetron and its two novel metabolites, 1-hydroxy-ondansetron diastereoisomers, MAGNETIC RESONANCE IN CHEMISTRY, 2006, 第 4 作者
（335） 苯磺酸氨氯地平片在健康人体的药动学及生物等效性评价, Assessment of pharmacokinetics and bioequivalence of amlodipine besylate in healthy volunteers, 第四军医大学学报, 2006, 第 5 作者
（336） Pharmacokinetics and metabolism of the flavonoid scutellarin in humans after a single oral administration, DRUG METABOLISM AND DISPOSITION, 2006, 第 1 作者
（337） Development and validation of a liquid chromatographic/tandem mass spectrometric method for the determination of sertraline in human plasma, RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2006, 第 1 作者
（338） LC-MS/MS快速测定人血浆中格列齐特, Rapid Determination of Gliclazide in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry Method, 中国药学杂志, 2006, 第 2 作者
（339） 葡磷酰胺在大鼠体内的代谢研究, Identification of glufosfamide metabolites in rats, 药学学报, 2006, 第 2 作者
（340） Pharmacokinetics and metabolic pathways of ginsenoside Rh2 in rat and dog, DRUG METABOLISM REVIEWS, 2006, 第 2 作者
（341） 复方盐酸二甲双胍片在健康人体的药代动力学和相对生物利用度, Pharmacokinetics and relative bioavailability of compound metformin hydrochloride tablet in healthy volunteers, 中国临床药理学杂志, 2005, 第 8 作者
（342） 细胞色素P450 CYP2C9＊3对格列本脲和氯诺昔康中国人体药代动力学的影响, Impact of cytochrome P450 CYP2C9 variant allele CYP2C9 ＊ 3 on the pharmacokinetics of glibenclamide and lornoxicam in Chinese subjects, 药学学报, 2005, 第 2 作者
（343） 雷贝拉唑肠溶制剂的人体相对生物利用度, The relative bioavailability of rabeprazole enteric-coated formulations in healthy volunteers, 中国医院药学杂志, 2005, 第 3 作者
（344） Influence of dosage forms on pharmacokinetics of daidzein and its main metabolite daidzein-7-O-glucuronide in rats, Influence of dosage forms on pharmacokinetics of daidzein and its main metabolite daidzein-7-O-glucuronide in rats, 中国药理学报：英文版, 2005, 第 2 作者
（345） 大豆苷元氨基甲酸酯类衍生物的合成及其抗缺氧活性, Synthesis and anti-hypoxia activity of a series of daidzein carbamates, 中国药物化学杂志, 2005, 第 2 作者
（346） 阿奇霉素干混悬剂在健康人体的药代动力学及生物等效性评价, Study on Pharmacokinetics and Bioequivalence of Azithromycin for Suspension in Healthy Volunteers, 解放军药学学报, 2005, 第 3 作者
（347） 液相色谱-电喷雾离子阱质谱法分析大鼠尿样中的黄芩苷及其异构体, Liquid Chromatography-Electrospray Ion Trap Mass Spectrometry Analysis of Baicalin and Its Isomer in Rats Urine, 质谱学报, 2004, 第 2 作者
（348） 液相色谱-串联质谱法测定比格犬血浆中氢吗啡酮, Determination of hydromorphone in Beagle dogs plasma by liquid chromatography-tandem mass spectrometry, 药学学报, 2004, 第 2 作者
（349） LC／MS／MS法测定比格犬血浆中特拉唑嗪及其在药物动力学研究中的应用, Determination of Terazosin in Beagle Dogs Plasma by LC/MS/MS and Its Application in the Pharmacokinetic Study, 药物分析杂志, 2004, 第 2 作者
（350） LC／MS／MS法测定血浆、羊水中曲马多及其活性代谢物氧去甲基曲马多, Determination of tramadol and its active metabolite O-desmethyltramadol in plasma and amniotic fluid using LC/MS/MS, 药学学报, 2004, 第 2 作者
（351） 液相色谱－质谱－质谱联用法测定人血浆中氯诺昔康, Determination of lornoxicam in human plasma by LC/MS/MS, 药学学报, 2004, 第 2 作者
（352） 人血浆中O-去甲右美沙芬的测定及药代动力学研究, Determination of dextrorphan in human plasma and pharmacokinetic study, 药学学报, 2004, 第 4 作者
（353） 克拉霉素缓释胶囊释放度与体内吸收度相关性的研究, Studies on Correlation between in vitro Release and in vivo Absorption of Clarithromycin Modified Release Capsules, 药物分析杂志, 2004, 第 2 作者
（354） LC／MS／MS法测定人血浆中非那雄胺的浓度及其药代动力学研究, Determination of Finasteride in Human Plasma by LC/MS/MS and Study on Its Pharmacokinetics, 中国临床药理学杂志, 2003, 第 2 作者
（355） 氯雷他定及其活性代谢物去羧乙氧基氯雷他定在中国健康受试者的药动学, 中国药理学报：英文版, 2003, 第 2 作者
（356） 液相色谱—质谱—质谱联用法测定猕猴血浆中阿德福韦, Determination of adefovir in monkey plasma by liquid chromatoography-tendem mass spectrometry, 药学学报, 2003, 第 2 作者
（357） 液相色谱—串联质谱法同时测定人血浆中伪麻黄碱和苯海拉明, Simultaneous determination of pseudoephedrine and diphenhydramine in human plasma by liquid chromatography-tandem mass spectrometry, 药学学报, 2003, 第 2 作者
（358） 国产甲磺酸倍他司汀片剂与其进口片人体生物等效性, Bioequivalence of Domestic and Imported Betahistine Mesylate Tablets in Healthy Volunteers, 中国临床药理学杂志, 2003, 第 3 作者
（359） 头孢克洛缓释片在健康人体的药代动力学及生物等效性, Pharmacokinetics and bioequivalence of cefaclor sustained release tablets in healthy volunteers, 中国临床药理学杂志, 2003, 第 3 作者
（360） 氯诺昔康在中国受试者体内药动学研究, 中国药理通讯, 2003, 第 2 作者
（361） 液相色谱—串联质谱法测定大鼠血浆中的汉黄芩素, Determination of wogonin in rat plasma by liquid chromatography-tandem mass spectrometry, 药学学报, 2002, 第 3 作者
（362） LC／MS／MS法测定人血浆中地洛他定：在药代动力学研究中的应用, Determination of Desloratadine in Human Plasma by LC/MS/MS: Application to Pharmacokinetic Study, 中国临床药理学杂志, 2002, 第 2 作者
（363） 液相色谱—质谱—质谱联用法快速测定人血浆中法莫替丁含量, Determination of the content of famotidine in the human plasma by liquid chromatography-tandem mass spectrometry, 沈阳药科大学学报, 2002, 第 2 作者
（364） 柱前手性衍生化—正相高效液相色谱法拆分甲基麻黄碱对映异构体, Enantiospecific analysis of methylephedrine by normal-phase HPLC with precolumn derivatization, 中国药学杂志, 2002, 第 3 作者
（365） 液相色谱—电喷雾串联质谱法测定血浆中克仑特罗, Determination of Clenbuteron in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry, 质谱学报, 2002, 第 1 作者
（366） 液相色谱—质谱联用法测定牛奶中4种四环素类药物残留量, Measurement of the four tetracycline residues in the milk by high-performance liquid chromatographymass spectrometry, 沈阳药科大学学报, 2002, 第 4 作者
（367） 大学生维生素C稳态血浆浓度分析, 沈阳药科大学学报, 2001, 第 6 作者
（368） 液相色谱-电喷雾串联质谱法测定血浆中二氢麦角胺及其8'-羟基代谢物, Sensitive and Specific Liquid Chromatographic- Tandem Mass Spectrometric Assay for Dihydroergotamine and Its Major Metabolite in Human Plasma, 分析测试学报, 2001, 第 1 作者
（369） 麻黄碱对映异构体的柱前手性衍生化—反相高效液相色谱法拆分, 分析测试学报, 2001, 第 4 作者
（370） 液相色谱—质谱—质谱联用法测定人血浆中氨氯地平, 药学学报, 2001, 第 1 作者
（371） 液相色谱—串联质谱法测定人血浆中的伪麻黄碱浓度, 沈阳药科大学学报, 2001, 第 3 作者
（372） 液相色谱—电喷雾离子阱质谱法检测体液中士的宁、马钱子碱及其主要代谢物, 药物分析杂志, 2001, 第 3 作者
（373） 液相色谱—电喷雾串联质谱法测定人血浆中班布特罗：在药代动力学研究中的应用, 药学学报, 2001, 第 5 作者
（374） 有机质谱在药物代谢研究中的应用, Application of Organic Mass Spectrometry to Drug Metabolism Research, 分析测试学报, 2001, 第 2 作者
（375） 采用微生物转化法合成5—羟基普萘洛尔, 药物生物技术, 2001, 第 1 作者
（376） 固相萃取—液相色谱—串联质谱法快速分析血浆中特布他林, 药学学报, 2001, 第 1 作者
（377） 反相高效液相色谱法测定大鼠血浆中水飞蓟宾的浓度, 沈阳药科大学学报, 2001, 第 3 作者
（378） 格列喹酮在中国健康受试者体内的生物等效性研究, 中国临床药理学杂志, 2000, 第 4 作者
（379） 氨氯地平在中国受试者体内的药物动力学及制剂的生物等效性, 沈阳药科大学学报, 2000, 第 4 作者
（380） 人尿中苯丙哌林羟基化代谢产物的研究, 药学学报, 2000, 第 1 作者
（381） LC/MS~n法鉴定二氧苯柳胺在家兔体内的主要代谢产物, 高等学校化学学报, 2000, 第 3 作者
（382） 苯丙哌林在健康人体内的对映体选择性药物动力学研究, 药学学报, 2000, 第 4 作者
（383） 6种口服降糖药的液相色谱—质谱分析, 分析测试学报, 2000, 第 1 作者
（384） 液相色谱—质谱联用法鉴定9种皮质激素药物, 药学学报, 1999, 第 3 作者
（385） 用电喷雾离子阱质谱法分析生物样品中艾司唑仑及其主要代谢物, 药物分析杂志, 1999, 第 3 作者
（386） 普罗帕酮在中国健康受试者体内的羟基化代谢产物研究, 药学学报, 1999, 第 1 作者
（387） 电喷雾离子陆质谱法直接测定几种药物的葡萄糖苷酸型代谢物, 药学学报, 1998, 第 1 作者
（388） 血浆中普罗帕酮及其活性代谢物5-羟基普罗帕酮对映体的选择性分析, 中国药学杂志, 1997, 第 1 作者
（389） 乙氧苯柳胺在家兔体内的主要代谢产物, 沈阳药科大学学报, 1996, 第 2 作者

（ 1 ） 高等药理学, 科学出版社, 2019-07, 第 其他 作者
（ 2 ） 个性化药物-新药研发的未来, 上海科技文献, 2020-03, 第 其他 作者

   

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（ 3 ） 创新药物临床前ADME评价, 负责人, 境内委托项目, 2022-01--2024-12
（ 4 ） 创新药物临床DMPK评价, 负责人, 境内委托项目, 2021-01--2025-12