基本信息
曹晓风  女  博导  中国科学院遗传与发育生物学研究所
电子邮件: xfcao@genetics.ac.cn
通信地址: 北京市朝阳区北辰西路1号院2号
邮政编码: 100101

招生信息

   
招生专业
071007-遗传学
071010-生物化学与分子生物学
071001-植物学
招生方向
植物表观遗传学
植物分子遗传学,植物功能基因组学
基因表达调控

教育背景

1993-09--1997-07   北京大学   博士
1988-09--1991-07   中国农业大学生物学院   硕士
1984-09--1988-07   北京大学   学士

工作经历

   
工作简历
2003-01~现在, 中科院遗传发育所, 研究员
1999-07~2003-07,美国加州大学洛杉矶分校, 助理研究员
1997-07~1998-07,美国华盛顿州立大学, 博士后
1995-07~1996-07,英国John Innes Center, 访问学者
1993-09~1997-07,北京大学, 博士
1991-07~1997-07,北京大学, 助教、讲师
1988-09~1991-07,中国农业大学生物学院, 硕士
1984-09~1988-07,北京大学, 学士
社会兼职
2017-01-01-今,《Journal of Genetics and Genomics》, 副主编
2017-01-01-今,《National Science Review》, 编委
2017-01-01-今,作物遗传改良国家重点实验室第六届学术委员会, 委员
2016-01-01-今,第五届国家农业转基因生物安全委员会, 委员
2014-01-01-今,《中国植物生理与植物分子生物学学会》, 理事
2014-01-01-今,《中国植物学会》, 理事
2013-01-01-今,《中国植物生理与植物分子生物学学会》 “植物生物学女科学家分会”, 副主任
2013-01-01-今,《中国科学:生命科学》, 副主编
2013-01-01-今,中国科学院第五届妇女工作委员会, 委员
2011-01-01-2014-12-31,《Biochemical Journal》, 编委
2010-01-01-今,《The Plant Cell》, 编委
2010-01-01-今,《Current Opinion in Plant Biology》, 编委
2010-01-01-2014-12-31,《植物生理学通讯》, 编委
2010-01-01-今,中国侨联特聘专家, 特聘专家
2010-01-01-今,中国侨联, 特聘专家
2009-01-01-2011-12-31,《Frontier in Biology》, 副主编
2008-01-01-今,《中国遗传学会》“表观遗传委员会”, 副主任
2007-01-01-今,《Journal of Genetics and Genomics》, 编委
2007-01-01-2012-12-31,《国际遗传学杂志》, 编委

教授课程

遗传与发育
表观遗传学
分子遗传学

专利与奖励

   
奖励信息
(1) 国家自然科学奖, 二等奖, 国家级, 2019
(2) 北京市科学技术二等奖, 二等奖, 市地级, 2015
(3) 中国青年女科学家奖, , 部委级, 2010
(4) 全国优秀科技工作者, , 国家级, 2010
(5) 杜邦青年科学家奖, 一等奖, 其他, 2008
专利成果
( 1 ) 一种组蛋白甲基化转移酶及其编码基因与应用, 2010, 第 1 作者, 专利号: ZL200710063118.6
( 2 ) 一种具有RNaseIII酶活性的Dicer蛋白及其编码基因与应用, 2010, 第 1 作者, 专利号: ZL200710121518.0
( 3 ) miR528的调控位点及其应用, 2019, 第 1 作者, 专利号: ZL201410423077.X
( 4 ) 水稻叶夹角的表观调控位点及其应用, 2018, 第 1 作者, 专利号: ZL201410038280.5

出版信息

   
发表论文
(1) The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature- and photoperiod-dependent flowering repressor, Nature Communications, 2019, 通讯作者
(2) DNA methylation repels targeting of Arabidopsis REF6, Nature Communications, 2019, 通讯作者
(3) Fine-Tuning of MiR528 Accumulation Modulates Flowering Time in Rice, Molecular Plant, 2019, 通讯作者
(4) G-content associated poly(A)-binding landscape and roles in enhancing translational efficiency, Genome Biology, 2019, 通讯作者
(5) Impact of poly(A)-tail G-content on Arabidopsis PAB binding and their role in enhancing translational efficiency, Genome Biology, 2019, 通讯作者
(6) MicroRNAs and Their Regulatory Roles in Plant-Environment Interactions, Annual Review of Plant Biology, 2019, 通讯作者
(7) The Histone H3K4 Demethylase JMJ16 Represses Leaf Senescence in Arabidopsis, The Plant Cell, 2019, 通讯作者
(8) An H3K27me3 demethylase-HSFA2 regulatory loop orchestrates transgenerational thermomemory in Arabidopsis, Cell Research, 2019, 通讯作者
(9) The seekers: how epigenetic modifying enzymes find their hidden genomic targets in Arabidopsis, Current Opinion in Plant Biology, 2018, 通讯作者
(10) Ribosomal RNA Biogenesis and Its Response to Chilling Stress in Oryza sativa, Plant Physiology, 2018, 通讯作者
(11) Context and Complexity: Analyzing Methylation in Trinucleotide Sequences, Trends in Plant Science, 2017, 通讯作者
(12) Roles of pre-mRNA splicing and polyadenylation in plant development, Current Opinion in Plant Biology, 2017, 通讯作者
(13) Structure of the Arabidopsis JMJ14–H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases, The Plant Cell, 2017, 通讯作者
(14) ROS accumulation and antiviral defence control by microRNA528 in rice, NATURE PLANTS, 2017, 通讯作者
(15) Small RNA Extraction and Detection in Rice (Oryza sativa), Curr. Protoc. Plant Biol., 2016, 通讯作者
(16) Epigenetic Regulation and the Epigenomic Landscape in Rice, National Science Review, 2016, 通讯作者
(17) The effect of transposable elements on phenotypic variation:insights from plants to humans, SCIENCE CHINA Life Sciences, 2016, 通讯作者
(18) Recruitment of the NineTeen Complex to the activated spliceosome requires AtPRMT5, Proc. Natl. Acad. Sci. USA, 2016, 通讯作者
(19) REF6 recognizes a specific DNA sequence to demethylate H3K27me3 and regulate organ boundary formation in Arabidopsis, Nature Genetics, 2016, 通讯作者
(20) C-terminal domains of histone demethylase JMJ14 interact with a pair of NAC transcription factors to mediate specific chromatin association, Cell Discovery, 2015, 通讯作者
(21) 蛋白质精氨酸甲基化参与基因转录后调控的研究进展, 生命科学, 2015, 通讯作者
(22) Circular RT-PCR Assay Using Arabidopsis Samples, Bio-protocol, 2015, 通讯作者
(23) Integrative genome-wide analysis reveals HLP1, a novel RNA-binding protein, regulates plant flowering by targeted alternative polyadenylation, Cell Research, 2015, 通讯作者
(24) Overview of the function of transposable elements in higher plants, Prog Biochem Biophys, 2015, 通讯作者
(25) New players in ABA signaling: identification of PUB12/13 involved in degradation of ABA co-receptor ABI1, SCIENCE CHINA Life Sciences, 2015, 通讯作者
(26) Arabidopsis Protein Arginine Methyltransferase 3 regulates ribosome biogenesis by affecting precursor ribosomal RNA processing, PNAS, 2014, 通讯作者
(27) RNase ZS1 processes UbL40 mRNAs and controls thermo-sensitive genic male sterility in rice, Nature Communications, 2014, 通讯作者
(28) Epigenetic regulation and functional exaptation of transposable elements in higher plants, Current Opinion in Plant Biology, 2014, 通讯作者
(29)  Control of transposon activity by a histone H3K4 demethylase in rice, PNAS, 2013, 通讯作者
(30) NOT2 proteins promote polymerase II-dependent transcription and interact with multiple miRNA biogenesis factors in Arabidopsis, The Plant Cell, 2013, 通讯作者
(31) Rice RNA-dependent RNA polymerase 6 acts in small RNA biogenesis and spikelet development, The Plant Journal, 2012, 通讯作者
(32) Roles of DCL4 and DCL3b in rice phased small RNA biogenesis, The Plant Journal, 2012, 通讯作者
(33) Arabidopsis REF6 is a Histone H3 Lysine 27 Demethylase, Nature Genetics, 2011, 通讯作者
(34) Arginine methylation mediated by AtPRMT5 is essential for proper pre-mRNA splicing.,  PNAS, 2010, 通讯作者
(35) Autocatalytic mechanisms for differential epigenetic modifications between genes and transposons within the Arabidopsis genome. , EMBO Journal, 2010, 通讯作者
(36) Histone methylation in higher plants. ., Annu Rev. Plant Biol, 2010, 通讯作者
(37) JMJ14 is an H3K4 demethylase and regulates flowering time in Arabidopsis. , Cell Res, 2010, 通讯作者
(38) Small RNA-directed Epigenetic Natural Variation in Arabidopsis thaliana, PLoS Genetics , 2008, 通讯作者
(39) Redundant requirement for a pair of PROTEIN ARGININE METHYLTRANSFERASE4 homologs for the proper regulation of Arabidopsis flowering time, Plant Physiology, 2008, 通讯作者
(40) Oryza sativa Dicer-like4 reveals a key role for small interfering RNA silencing in plant development, The Plant Cell, 2007, 通讯作者
(41) SDG714, a histone H3K9 methyltransferase involves in Tos17 DNA methylation and transposition in Oryza sativa L, The Plant Cell, 2007, 通讯作者
(42) Involvement of the histone acetyltransferase AtHAC1 in the regulation of flowering time via repression of FLC in Arabidopsis thaliana, Plant Physiology, 2007, 通讯作者
(43) Mutations in the type II protein arginine methyltransferase AtPRMT5 result in pleiotropic developmental defects in Arabidopsis thaliana, Plant Physiology, 2007, 通讯作者
(44) Regulation of Flowering Time by a Protein Arginine Methyltransferase, AtPRMT10, EMBO Reports, 2007, 通讯作者
(45) Loss of Function of OsDCL1 Affects MicroRNA Accumulation and Causes Developmental Defects in Rice, Plant Physiology, 2005, 通讯作者
发表著作
( 1 ) 承续的魅力:令人着迷的表观遗传学, 科学出版社, 2018-11, 第 1 作者

科研活动

   
科研项目
( 1 ) 植物重要器官形成的遗传和表观遗传调控机理研究, 主持, 国家级, 2009-01--2013-12
( 2 ) 专项/项目/课题-水稻耐逆境胁迫的分子模块解析, 主持, 部委级, 2013-08--2018-07
( 3 ) 拟南芥蛋白质精氨酸甲基化修饰的功能解析, 主持, 国家级, 2014-01--2018-12
( 4 ) 核糖体RNA的加工和修饰调控植物生长发育的分子机理研究, 主持, 国家级, 2016-01--2019-12
( 5 ) 拟南芥AGO蛋白与mRNA互做网络的解析及miRNA调控蛋白翻译抑制的分子机理研究, 主持, 国家级, 2013-01--2017-12
( 6 ) 基因表达调控技术研究, 主持, 国家级, 2016-01--2020-12
( 7 ) 水稻功能基因组研究与应用, 主持, 国家级, 2016-07--2020-12
( 8 ) 水稻抗低温冷害的遗传及表观遗传调控网络研究, 主持, 部委级, 2017-06--2022-12
( 9 ) 植物可塑性发育的分子调控机制, 主持, 部委级, 2018-06--2023-05
( 10 ) 未来作物分子设计, 主持, 国家级, 2018-01--2022-12
参与会议
(1)Dynamic histone methylation involved in regulation of plant development and genome stability in higher plants   2019-08-23
(2)表观遗传调控及水稻温敏雄性不育系机理研究   水稻种业发展院士专家高峰论坛   2019-06-30
(3) The targeting mechanism of histone demethylases in Arabidopsis   2019-06-16
(4)Mechanisms and functions of dynamic histone methylation in higher plants   第四届全国玉米生物学学术讨论会   2019-04-19
(5)Functional analysis of miR528 in rice   2019-01-12
(6)非编码RNA与未来农业   香山科学会议“核糖核酸与生命调控及健康” (第632次学术研讨会)   2018-08-27
(7)Molecular mechanisms of histone demethylases in genome-wide targeting in Arabidopsis    2018年第四届海峡两岸生命科学论坛   2018-08-27
(8)Molecular mechanisms of histone demethylases in substrate specificity and genome-wide targeting in Arabidopsis   2018-08-05
(9)Molecular mechanisms of histone demethylases in genome-wide targeting in Arabidopsis   2017-07-23
(10)Society of Chinese Bioscientists in America (SCBA), The 16th International symposium (2017 SCBA)   2017-06-29
(11)Insight of histone demethylases targeting in Arabidopsis   2017-06-19
(12)Insight of histone demethylases targeting in Arabidopsis   2017-05-18
(13)The importance of protein arginine methylation   2017-03-27
(14)Widespread Regulation of Alternative Splicing and Polyadenylation by Protein Arginine Methyltransferases   2016-11-29
(15)Transposable Elements: Junk DNA or Not?   2016-11-04
(16)高等植物组蛋白甲基化调控的分子机理研究    中国生物化学与分子生物学会 2016年全国学术会议   2016-10-20
(17) Epigenetic regulation in rice   2016-08-19
(18)Molecular mechanisms of histone demethylases in genome-wide targeting in Arabidopsis.   2016-05-09
(19)揭秘跳跃基因的功能   植物生物学女科学家分会第三届学术交流会   2016-04-01
(20)Dynamic histone lysine methylation controlling genome stability and development in higher plants   2016-02-15
(21)Molecular analysis of histone demethylases in genome-wide targeting in Arabidopsis   2015-10-25
(22) How do histone demethylases find genome-wide targets in Arabidopsis?   第十一次全国基因功能与表观遗传调控学术研讨会   2015-10-13
(23)Epigenetic regulation in higher plants    2015-07-13
(24) How do histone demethylases find genome-wide targets in Arabidopsis   第十一届两岸三地植物生物技术研讨会   2015-06-24
(25)水稻表观遗传组学研究进展和发展   香山科学会议--水稻功能基因组研究的现状和未来   2015-01-21
(26)Controlling thermo-sensitive genic male sterility by a posttranscriptional mechanism in rice.   2014-11-10
(27)Posttranscriptional regulation mediated by arginine methylation in Arabidopsis   中国植物生理与植物分子生物学学会第十一次会员代表大会暨全国学术年会—植物科学大趋势与大发展   2014-08-07
(28)Epigenetic regulation in rice   2014-05-20
(29)Epigenetic regulation in higher plants   2014-05-05
(30)RNase Zs1 controls thermo-sensitive genic male sterility in rice   2014-04-21
(31)Point Mutations of Splicing Factor AtPrp8 Suppress the Splicing Defects of atprmt5 Mutants   2014-04-12
(32)表观遗传调控水稻转座子活性和水稻发育的分子机制   遗传学与表观遗传学前沿暨第三届中国青年遗传学家论坛   2014-04-11
(33)Comparative epigenomic analysis between model plant and crop   2014-03-31
(34)Posttranscriptional regulation mediated by protein arginine methyltransferases in Arabidopsis thaliana   2013-06-24
(35)How plant cell distinguish active genes vs transposable element   2013-04-13
(36)Deciphering histone methylation and demethylation in higher plants   2011-01-15