基本信息
汪海林  男  博导  中国科学院生态环境研究中心
电子邮件: HLWang@rcees.ac.cn
通信地址: 北京市海淀区双清路18号
邮政编码: 100085

招生信息

   
招生专业
070302-分析化学
0710Z1-基因组学
招生方向
高灵敏生物分析
DNA损伤与修复
表观遗传学

教育背景

1994-09--1997-06   中科院大连化学物理研究所   理学博士
1991-09--1994-08   中科院大连化学物理研究所   理学硕士
1987-09--1991-07   武汉大学化学系   理学学士

工作经历

   
工作简历
2005-12~现在, 中科院生态环境研究中心, 研究员、博士生导师
2000-07~2005-12,University of Alberta, postdoctoral fellow, research associate
1997-07~2000-07,中科院大连化物所, 助研、副研
社会兼职
2018-01-01-2020-12-31,Analytical Chemistry, 编委
2017-10-01-今,Journal of Environmental Sciences, 编委
2016-03-01-今,北京理化分析测试协会色谱分会, 副理事长
2016-01-01-今,Genomics, Proteomics & Bioinformatics, 编委
2013-08-01-今,J Sep Sci, 编委
2013-01-01-今,《中国科学化学》, 编委
2010-01-01-今,《环境化学》, 编委

教授课程

前沿讲座
环境与健康
环境健康前沿研究
环境与健康前沿研究

专利与奖励

   
奖励信息
(1) 中国分析测试协会科学技术奖, 特等奖, 其他, 2015
(2) 中科院优秀研究生导师奖, 院级, 2015
(3) 中国分析测试协会科学技术奖, 一等奖, 其他, 2013
(4) 中科院优秀研究生指导教师奖, 院级, 2013
(5) 中科院优秀研究生导师奖, 院级, 2012
(6) 中国分析测试协会科学技术奖, 一等奖, 其他, 2010
(7) 中国教育部自然科学奖, 一等奖, 部委级, 2007
(8) 中科院院长奖学金特别奖, 特等奖, 其他, 1997
专利成果
( 1 ) 脂蛋白毛细管涂层及其制备方法, 发明, 2008, 第 1 作者, 专利号: 200810240105.9
( 2 ) 荧光偏振增强免疫毛细管电泳分析, 发明, 2009, 第 1 作者, 专利号: 200910092316.7
( 3 ) 量子点增强的高灵敏DNA加合物分析方法, 发明, 2009, 第 1 作者, 专利号: 20091023697.2
( 4 ) 毛细管电泳-柱上激光诱导荧光偏振检测装置, 发明, 2009, 第 1 作者, 专利号: 200910088212.9
( 5 ) 一种用于DNA酶切为单核苷的级联酶反应器, 发明, 2016, 第 1 作者, 专利号: 201610544434.7

出版信息

   
发表论文
[1] Liu, Yan, Lai, Weiyi, Wang, Hailin. Artificially Evolved Superbinder for Specific Recognition of N6-Methyladenine Base Modification in DNA and RNA. ANALYTICAL CHEMISTRY[J]. 2023, 95(18): 7071-7075, http://dx.doi.org/10.1021/acs.analchem.3c00588.
[2] Lyu, Cong, Wang, HuiDong, Lai, Weiyi, Wang, Hailin. Identification and quantification of DNA N6-methyladenine modification in mammals: A challenge to modern analytical technologies. CURRENT OPINION IN CHEMICAL BIOLOGYnull. 2023, 73: http://dx.doi.org/10.1016/j.cbpa.2022.102259.
[3] 汪海林. N6-methyl-20 -deoxyadenosine promotes selfrenewal of BFU-E progenitor in erythropoiesis. iScience[J]. 2023, [4] Tretyakova, Natalia Y, Motwani, Hitesh V, Wang, Hailing, Dai, Jiayin. Call for Papers for a Special Issue on Mass Spectrometry Advances for Environmental and Human Health. CHEMICAL RESEARCH IN TOXICOLOGY. 2023, 36(3): 331-331, http://dx.doi.org/10.1021/acs.chemrestox.3c00027.
[5] Yu, Fangzhi, Zhang, Dapeng, Zhao, Chubin, Zhao, Qiang, Jiang, Guibin, Wang, Hailin. Flanking strand separation activity of RecA nucleoprotein filaments in DNA strand exchange reactions. NUCLEIC ACIDS RESEARCH[J]. 2023, 51(5): 2270-2283, http://dx.doi.org/10.1093/nar/gkad078.
[6] Chen, Shaokun, Lai, Weiyi, Li, Yanan, Liu, Yan, Jiang, Jie, Li, Xiangjun, Jiang, Guibin, Wang, Hailin. Aberrant DNA N-6-methyladenine incorporation via adenylate kinase 1 is suppressed by ADAL deaminase-dependent 2'-deoxynucleotide pool sanitation. EMBO JOURNAL[J]. 2023, 42(15): http://dx.doi.org/10.15252/embj.2023113684.
[7] 汪海林. Highly Efficient Gel Electrophoresis for Accurate Quantification of Nucleic Acid Modifications via in-Gel Digestion with UHPLC-MS/MS. Anal Chem[J]. 2023, 95: 13407-13411, [8] Li, Yanan, Wang, Yan, Fang, Zheng, Liu, Yan, Zhu, He, Yao, Yating, You, Xin, Qin, Hongqiang, Ye, Mingliang, Wang, Hailin. Temporal Tracking of Insulin Action on the Cell Surface of Proteins at a Resolution of Ten Seconds. ANALYTICAL CHEMISTRY[J]. 2023, 95(24): 9323-9329, http://dx.doi.org/10.1021/acs.analchem.3c01354.
[9] 汪海林. Aberrant DNA N6 -methyladenine incorporation via adenylate kinase 1 is suppressed by ADAL deaminase-dependent 20 -deoxynucleotide pool sanitation. Embo J[J]. 2023, e113684: [10] Wu, Danni, Li, Yao, Li, Cuiping, Zhong, Shangwei, Liu, Baodong, Hang, Haiying, Wang, Hailin. MDM2 Antagonist Nutlin-3 Stimulates Global DNA Hydroxymethylation by Enhancing p53-TET1 Signaling Axis. ACS CHEMICAL BIOLOGY. 2023, http://dx.doi.org/10.1021/acschembio.3c00247.
[11] Wang Xiuzhi, Wang Mengke, Dai Xinyuan, Han Xiao, Zhou Yu, Lai Weiyi, Zhang Liyuan, Yang Ying, Chen Yusheng, Wang Hailin, Zhao Yong-Liang, Shen Bin, Zhang Yuhan, Huang Ying, Yang Yun-Gui. RNA 5-methylcytosine regulates YBX2-dependent liquid-liquid phase separation. Fundamental Research[J]. 2022, 2: 48-55, [12] Kong, Yimeng, Cao, Lei, Deikus, Gintaras, Fan, Yu, Mead, Edward A, Lai, Weiyi, Zhang, Yizhou, Yong, Raymund, Sebra, Robert, Wang, Hailin, Zhang, XueSong, Fang, Gang. Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolution. SCIENCE[J]. 2022, 375(6580): 515-+, http://dx.doi.org/10.1126/science.abe7489.
[13] Huang, Xin, Bashkenova, Nazym, Hong, Yantao, Lyu, Cong, Guallar, Diana, Hu, Zhe, Malik, Vikas, Li, Dan, Wang, Hailin, Shen, Xiaohua, Zhou, Hongwei, Wang, Jianlong. A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency. CELL REPORTS[J]. 2022, 39(10): http://dx.doi.org/10.1016/j.celrep.2022.110928.
[14] Song, Xingrui, Song, Xinyue, Lai, Weiyi, Wang, Hailin. Hyperactive DNA Cutting for Unbiased UHPLC-MS/MS Quantification of Epigenetic DNA Marks by Engineering DNase I Mutants. ANALYTICAL CHEMISTRY[J]. 2022, 94(50): 1-7, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000895285200001.
[15] 汪海林. Rare and misincorporated DNA N6 -methyladenine. Cell Discovery[J]. 2022, 8: 39-, [16] Chen, Shaokun, Lai, Weiyi, Li, Xiangjun, Wang, Hailin. Necrosulfonamide Selectively Induces DNA Double-Strand Breaks in Acute Myeloid Leukemia Cells. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2022, 35(3): 387-391, http://dx.doi.org/10.1021/acs.chemrestox.2c00044.
[17] Lai, Weiyi, Wang, Hailin. Detection and Quantification of UV-irradiation-induced DNA Damages by Liquid Chromatography-Mass Spectrometry and Immunoassay(dagger). PHOTOCHEMISTRY AND PHOTOBIOLOGYnull. 2022, 98(3): 598-608, http://dx.doi.org/10.1111/php.13546.
[18] Ren, Yun, Zheng, Jing, Wang, Hailin. Transiently gene-modulated cell reporter for ultrasensitive detection of estrogen-like compounds in tap water. CHEMOSPHERE[J]. 2022, 289: http://dx.doi.org/10.1016/j.chemosphere.2021.133161.
[19] Fang, Tianjiao, Tang, Chao, Yin, Junfa, Wang, Hailin. Magnetic multi-enzyme cascade combined with liquid chromatography tandem mass spectrometry for fast DNA digestion and quantitative analysis of 5-hydroxymethylcytosine in genome of human bladder cancer T24 cells induced by tetrachlorobenzoquinone. JOURNAL OF CHROMATOGRAPHY A[J]. 2022, 1676: http://dx.doi.org/10.1016/j.chroma.2022.463279.
[20] Lai, Weiyi, Wang, Hailin. Detection and Quantification of UV-irradiation-induced DNA Damages by Liquid Chromatography-Mass Spectrometry and Immunoassay †. PHOTOCHEMISTRY AND PHOTOBIOLOGYnull. 2022, 98(3): 598-608, http://dx.doi.org/10.1111/php.13546.
[21] Hao, Jinghua, Cao, Dong, Zhao, Qiang, Zhang, Dapeng, Wang, Hailin. Intramolecular Folding of PolyT Oligonucleotides Induced by Cooperative Binding of Silver(I) Ions. MOLECULES[J]. 2022, 27(22): 7842-1, http://dx.doi.org/10.3390/molecules27227842.
[22] Fang, Tianjiao, Tang, Chao, Yin, Junfa, Wang, Hailin. Magnetic multi-enzyme cascade combined with liquid chromatography tandem mass spectrometry for fast DNA digestion and quantitative analysis of 5-hydroxymethylcytosine in genome of human bladder cancer T24 cells induced by tetrachlorobenzoquinone. JOURNAL OF CHROMATOGRAPHY A[J]. 2022, 1676: http://dx.doi.org/10.1016/j.chroma.2022.463279.
[23] Liu, Shuyu, Yang, Renjun, Chen, Yongjiu, Zhao, Xingchen, Chen, Shaokun, Yang, Xuezhi, Cheng, Zhanwen, Hu, Bowen, Liang, Xiaoxing, Yin, Nuoya, Liu, Qian, Wang, Hailin, Liu, Sijin, Faiola, Francesco. Development of Human Lung Induction Models for Air Pollutants' Toxicity Assessment. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2021, 55(4): 2440-2451, https://www.webofscience.com/wos/woscc/full-record/WOS:000620926800025.
[24] Ma, Yangde, Zhang, Ning, Chen, Shaokun, Sun, Jingwei, Liu, Yan, Li, Xiangjun, Wang, Hailin. One-pot intramolecular cyclization of 5-hydroxymethylcytosine for sequencing DNA hydroxymethylation at single-base resolution. ANALYST[J]. 2021, 146(3): 820-824, http://dx.doi.org/10.1039/d0an01981j.
[25] Liang, Ying, Lu, Qi, Li, Wei, Zhang, Dapeng, Zhang, Fanglin, Zou, Qingping, Chen, Lu, Tong, Ying, Liu, Mengxing, Wang, Shaoxuan, Li, Wenxuan, Ren, Xiaoguang, Xu, Peng, Yang, Zhicong, Dong, Shihua, Zhang, Baolong, Huang, Yanni, Li, Daqiang, Wang, Hailin, Yu, Wenqiang. Reactivation of tumour suppressor in breast cancer by enhancer switching through NamiRNA network. NUCLEIC ACIDS RESEARCH[J]. 2021, 49(15): 8556-8572, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000697383500017.
[26] Yuan, Zheng, Yu, Fangzhi, Zhang, Dapeng, Wang, Hailin. Profiling of the assembly of RecA nucleofilaments implies a potential target for environmental factors to disturb DNA repair. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2021, 102(4): 283-290, http://dx.doi.org/10.1016/j.jes.2020.09.022.
[27] Chen, Zheng, Liu, Yan, Wang, Hailin. Conjoint expression and purification strategy for acquiring proteins with ultra-low DNA N-6-methyladenine backgrounds in Escherichia coli. BIOSCIENCE REPORTS[J]. 2021, 41(3): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960888/.
[28] Hailin Wang. Profiling of the assembly of RecA nucleofilaments implies a potential target for environmental factors to disturb DNA damage repair. J. Environ. Sci. (China). 2021, [29] Li, Yapiao, Yu, Fangzhi, Chen, Shaokun, Zhang, Ning, Wang, Hailin, Zhao, Qiang. Immunoassay of Small Molecule Mediated by a Triply Functional DNA. ANALYTICAL CHEMISTRY[J]. 2021, 93(11): 4794-4799, http://dx.doi.org/10.1021/acs.analchem.0c05386.
[30] Zhang, Rui, Lai, Weiyi, Wang, Hailin. Quantification of Epigenetic DNA Modifications in the Subchromatin Structure Matrix Attachment Regions by Stable Isotope Dilution UHPLC-MS/MS Analysis. ANALYTICAL CHEMISTRY[J]. 2021, 93(47): 15567-15572, http://dx.doi.org/10.1021/acs.analchem.1c04151.
[31] Liu, Xiaoling, Lai, Weiyi, Li, Yao, Chen, Shaokun, Liu, Baodong, Zhang, Ning, Mo, Jiezhen, Lyu, Cong, Zheng, Jing, Du, YaRui, Jiang, Guibin, Xu, GuoLiang, Wang, Hailin. N-6-methyladenine is incorporated into mammalian genome by DNA polymerase. CELL RESEARCHnull. 2021, 31(1): 94-97, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=6896535&detailType=1.
[32] Liu, Baodong, Wang, Hailin, Hu, S. Detection of N-6-Methyladenine in Eukaryotes. CANCER METABOLOMICS: METHODS AND APPLICATIONS[J]. 2021, 1280: 83-95, http://dx.doi.org/10.1007/978-3-030-51652-9_6.
[33] Yuan, Zheng, Zhang, Dapeng, Yu, Fangzhi, Ma, Yangde, Liu, Yan, Li, Xiangjun, Wang, Hailin. Precise sequencing of single protected-DNA fragment molecules for profiling of protein distribution and assembly on DNA. CHEMICAL SCIENCE[J]. 2021, 12(6): 2039-2049, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8179319/.
[34] Zheng Chen, Hailin Wang. Antibiotic Toxicity Profiles of Escherichia coli Strains Lacking DNA Methyltransferases. ACS OMEGA[J]. 2021, 6(11): 7834-7840, https://doaj.org/article/d2bd20482c4c4861a7a255f25aa68865.
[35] 宋星睿, 凌晓婷, 赵楚斌, 赖玮毅, 汪海林. DNA胞嘧啶的甲基化与去甲基化进展. 分析科学学报[J]. 2021, 37(4): 473-478, http://lib.cqvip.com/Qikan/Article/Detail?id=7105552084.
[36] Ren, Yun, Liu, Yan, Wang, Hailin. Identification of epigenetic regulators in the estrogen signaling pathway via siRNA screening. MOLECULAR OMICS[J]. 2021, 17(4): 596-606, http://dx.doi.org/10.1039/d1mo00040c.
[37] Li, Zhe, Lyu, Cong, Ren, Yun, Wang, Hailin. Role of TET Dioxygenases and DNA Hydroxymethylation in Bisphenols-Stimulated Proliferation of Breast Cancer Cells. ENVIRONMENTAL HEALTH PERSPECTIVES[J]. 2020, 128(2): http://dx.doi.org/10.1289/EHP5862.
[38] Hailin Wang. Fluorescent imaging of cytoplasmic nucleolin in live cells by functionalized-engineered aptamer.. Chem Comm. 2020, [39] Li, Yapiao, Zhang, Ning, Wang, Hailin, Zhao, Qiang. Fluorescence Anisotropy-Based Signal-Off and Signal-On Aptamer Assays Using Lissamine Rhodamine B as a Label for Ochratoxin A. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2020, 68(14): 4277-4283, http://dx.doi.org/10.1021/acs.jafc.0c00549.
[40] Shi, Boyang, Zhang, Jinsong, Heng, Jian, Gong, Jing, Zhang, Ting, Li, Pan, Sun, BaoFa, Yang, Ying, Zhang, Ning, Zhao, YongLiang, Wang, HaiLin, Liu, Feng, Zhang, Qiangfeng Cliff, Yang, YunGui. RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function. GENOME BIOLOGY[J]. 2020, 21(1): http://dx.doi.org/10.1186/s13059-020-02022-2.
[41] Li, Jialun, Wang, Ruiping, Jin, Jianyu, Han, Mengmeng, Chen, Zhaosu, Gao, Yingying, Hu, Xueli, Zhu, Haijun, Gao, Huifang, Lu, Kongbin, Shao, Yanjiao, Lyu, Cong, Lai, Weiyi, Li, Pishun, Hu, Guang, Li, Jiwen, Li, Dali, Wang, Hailin, Wu, Qihan, Wong, Jiemin. USP7 negatively controls global DNA methylation by attenuating ubiquitinated histone-dependent DNMT1 recruitment. CELL DISCOVERY[J]. 2020, 6(1): http://dx.doi.org/10.1038/s41421-020-00188-4.
[42] 余方志, 章大鹏, 袁征, 赵强, 汪海林. 亲和毛细管电泳技术在蛋白质-DNA相互作用研究中的应用. 色谱[J]. 2020, 38(10): 1133-1142, https://www.chrom-china.com/CN/10.3724/SP.J.1123.2020.03007.
[43] Li, Yapiao, Zhang, Ning, Wang, Hailin, Zhao, Qiang. An immunoassay for ochratoxin A using tetramethylrhodamine-labeled ochratoxin A as a probe based on a binding-induced change in fluorescence intensity. ANALYST[J]. 2020, 145(2): 651-655, https://www.webofscience.com/wos/woscc/full-record/WOS:000508560800033.
[44] Zhao, Qiang, Bai, Yunlong, Wang, Hailin. Directing a rational design of aptamer-based fluorescence anisotropy assay for sensitive detection of immunoglobulin E by site-specific binding study. TALANTA[J]. 2020, 217: http://dx.doi.org/10.1016/j.talanta.2020.121018.
[45] Tang, Yongyan, Gao, ChunChun, Gao, Ying, Yang, Ying, Shi, Boyang, Yu, JiaLi, Lyu, Cong, Sun, BaoFa, Wang, HaiLin, Xu, Yunyuan, Yang, YunGui, Chong, Kang. OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature. DEVELOPMENTAL CELL[J]. 2020, 53(3): 272-+, http://dx.doi.org/10.1016/j.devcel.2020.03.009.
[46] Yu, Fangzhi, Yuan, Zheng, Zhang, Dapeng, Liu, Yan, Zhao, Qiang, Wang, Hailin. High-affinity and undissociated capillary electrophoresis for DNA strand exchange analysis. CHEMICAL COMMUNICATIONS[J]. 2020, 56(54): 7403-7406, https://www.webofscience.com/wos/woscc/full-record/WOS:000545820900031.
[47] 赖玮毅, 汪海林. 哺乳动物基因组中由DNA聚合酶掺入的N^6-甲基腺嘌呤. 生命的化学[J]. 2020, 40(5): 810-, http://lib.cqvip.com/Qikan/Article/Detail?id=7102221681.
[48] Yu Fangzhi, Zhang Dapeng, Yuan Zheng, Zhao Qiang, Wang Hailin. Application of affinity capillary electrophoresis in the study of protein-DNA interactions. CHINESE JOURNAL OF CHROMATOGRAPHY[J]. 2020, 38(10): 1133-1142, [49] Zhao, Chao, Yong, Ting, Zhang, Yinbin, Jin, Yaofeng, Xiao, Yu, Wang, Hailin, Zhao, Bin, Cai, Zongwei. Evaluation of the splenic injury following exposure of mice to bisphenol S: A mass spectrometry-based lipidomics and imaging analysis. ENVIRONMENT INTERNATIONAL[J]. 2020, 135: [50] Hailin Wang. Protonation-suppressing free LC-MS/MS analysis for profiling of DNA cytosine modifications in adult Mice. Anal Chem. 2020, [51] Mo, Jiezhen, Liang, Ziyu, Lu, Meiling, Wang, Hailin. Protonation-Suppression-Free LC-MS/MS Analysis for Profiling of DNA Cytosine Modifications in Adult Mice. ANALYTICAL CHEMISTRY[J]. 2020, 92(11): 7430-7436, http://dx.doi.org/10.1021/acs.analchem.0c00962.
[52] Yuan, Zheng, Xu, Peng, Yu, Fangzhi, Zhang, Dapeng, Zhao, Qiang, Yu, Wenqiang, Wang, Hailin. An electroosmotic flow-free two-direction migration strategy enables fast affinity capillary electrophoresis to study the weak interactions between basic peptides and RNA. ANALYTICAL METHODS[J]. 2020, 12(48): 5833-5838, https://www.webofscience.com/wos/woscc/full-record/WOS:000603082600006.
[53] Yin, Junfa, Chen, Shaokun, Songa, Yuanyuan, Wang, Hailin. Fluorescent imaging of cytoplasmic nucleolin in live cells by a functionalized-engineered aptamer. CHEMICAL COMMUNICATIONS[J]. 2020, 56(91): 14171-14174, http://dx.doi.org/10.1039/d0cc06347a.
[54] Zhang, Ning, Deng, Wenchao, Li, Yao, Ma, Yangde, Liu, Yan, Li, Xiangjun, Wang, Hailin. Formic Acid of ppm Enhances LC-MS/MS Detection of UV Irradiation-Induced DNA Dimeric Photoproducts. ANALYTICAL CHEMISTRY[J]. 2020, 92(1): 1197-1204, http://dx.doi.org/10.1021/acs.analchem.9b04327.
[55] Hailin Wang. Quantitative assessment of adenosine triphosphatase hydrolytic activity by ultrafiltration-coupled ion-pair reversed-phase high-performance liquid chromatography. J. Sep. Sci.. 2020, [56] Zhang, Huifang, Gao, Qinqin, Tan, Shuo, You, Jia, Lyu, Cong, Zhang, Yunpeng, Han, Mengmeng, Chen, Zhaosu, Li, Jialun, Wang, Hailin, Liao, Lujian, Qin, Jun, Li, Jiwen, Wong, Jiemin. SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1. NUCLEIC ACIDS RESEARCH[J]. 2019, 47(17): 9053-9068, http://dx.doi.org/10.1093/nar/gkz626.
[57] Yu, Fangzhi, Zhao, Qiang, Zhang, Dapeng, Yuan, Zheng, Wang, Hailin. Affinity Interactions by Capillary Electrophoresis: Binding, Separation, and Detection. ANALYTICAL CHEMISTRY[J]. 2019, 91(1): 372-387, http://dx.doi.org/10.1021/acs.analchem.8b04741.
[58] Chen, Xin, Li, Ang, Sun, BaoFa, Yang, Ying, Han, YaNan, Yuan, Xun, Chen, RiXin, Wei, WenSu, Liu, Yanchao, Gao, ChunChun, Chen, YuSheng, Zhang, Mengmeng, Ma, XiaoDan, Liu, ZhuoWei, Luo, JunHang, Lyu, Cong, Wang, HaiLin, Ma, Jinbiao, Zhao, YongLiang, Zhou, FangJian, Huang, Ying, Xie, Dan, Yang, YunGui. 5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs. NATURE CELL BIOLOGY[J]. 2019, 21(8): 978-+, http://dx.doi.org/10.1038/s41556-019-0361-y.
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[120] Zhang, Guoqiang, Huang, Hua, Liu, Di, Cheng, Ying, Liu, Xiaoling, Zhang, Wenxin, Yin, Ruichuan, Zhang, Dapeng, Zhang, Peng, Liu, Jianzhao, Li, Chaoyi, Liu, Baodong, Luo, Yuewan, Zhu, Yuanxiang, Zhang, Ning, He, Shunmin, He, Chuan, Wang, Hailin, Chen, Dahua. N-6-Methyladenine DNA Modification in Drosophila. CELL[J]. 2015, 161(4): 893-906, http://dx.doi.org/10.1016/j.cell.2015.04.018.
[121] Li, Jinhua, Wang, Wei, Moe, Birget, Wang, Hailin, Li, XingFang. Chemical and Toxicological Characterization of Halobenzoquinones, an Emerging Class of Disinfection Byproducts. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2015, 28(3): 306-318, http://ir.rcees.ac.cn/handle/311016/32535.
[122] 尹俊发, 宋媛媛, 徐田, 张宁, 宋茂勇, 汪海林. 分子印迹纳米材料用于DNA损伤的荧光成像分析. 第二十届全国色谱学术报告会及仪器展览会null. 2015, http://ir.rcees.ac.cn/handle/311016/33395.
[123] 赖玮毅, 汪海林. 高效液相色谱串联电喷雾四级杆飞行时间质谱检测RNA寡核苷酸. 第二十届全国色谱学术报告会及仪器展览会null. 2015, http://ir.rcees.ac.cn/handle/311016/33392.
[124] 徐田, 张宁, 赵超, 宋媛媛, 尹俊发, 宋茂勇, 汪海林. 级联固定化酶微反应器的制备及用于DNA损伤分析. 第二十届全国色谱学术报告会及仪器展览会null. 2015, http://ir.rcees.ac.cn/handle/311016/33394.
[125] 张宁, 徐田, 尹俊发, 汪海林, 张维冰. 有机-无机杂化毛细管整体基质DNA微酶反应器的制备与应用. 第二十届全国色谱学术报告会及仪器展览会null. 2015, http://ir.rcees.ac.cn/handle/311016/33391.
[126] Liu, Shengquan, Zhang, Dapeng, Wang, Hailin. Transient Isotachophoresis Focusing of DNA and DNA-Protein Complexes Is Essentially Enhanced by Spontaneously Dissolved Aerial Carbon Dioxide in Electrolytes. ANALYTICAL CHEMISTRY[J]. 2015, 87(1): 554-560, http://dx.doi.org/10.1021/ac504173b.
[127] Zhao, Qiang, Lv, Qin, Wang, Hailin. Aptamer fluorescence anisotropy sensors for adenosine triphosphate by comprehensive screening tetramethylrhodamine labeled nucleotides. BIOSENSORS & BIOELECTRONICS[J]. 2015, 70(1): 188-193, http://dx.doi.org/10.1016/j.bios.2015.03.031.
[128] Yin, Junfa, Song, Yuanyuan, Zhang, Ning, Xu, Tian, Wang, Hailin. A fluorophore-conjugated ascorbic acid functions for the visualization of sodium vitamin C transporters in living cells. ANALYTICAL METHODS[J]. 2015, 7(22): 9663-9672, http://ir.rcees.ac.cn/handle/311016/32501.
[129] Qiang Zhao, Qin Lv, Hailin Wang. Aptamer fluorescence anisotropy sensors for adenosine triphosphate by comprehensive screening tetramethylrhodamine labeled nucleotides. BIOSENSORS AND BIOELECTRONICS. 2015, 70: 188-193, http://dx.doi.org/10.1016/j.bios.2015.03.031.
[130] Chen, Jiayu, Gao, Yawei, Huang, Hua, Xu, Kai, Chen, Xia, Jiang, Yonghua, Li, Hui, Gao, Shuai, Tao, Yu, Wang, Hong, Zhang, Yong, Wang, Hailin, Cai, Tao, Gao, Shaorong. The Combination of Tet1 with Oct4 Generates High-Quality Mouse-Induced Pluripotent Stem Cells. STEM CELLS[J]. 2015, 33(3): 686-698, http://dx.doi.org/10.1002/stem.1879.
[131] Zhang, Dapeng, Fu, Rong, Zhao, Qiang, Rong, Haiqin, Wang, Hailin. Nanoparticles-Free Fluorescence Anisotropy Amplification Assay for Detection of RNA Nucleotide-Cleaving DNAzyme Activity. ANALYTICAL CHEMISTRY[J]. 2015, 87(9): 4903-4909, http://ir.rcees.ac.cn/handle/311016/32628.
[132] 宋媛媛, 张宁, 尹瑞川, 尹俊发, 汪海林. 荧光修饰抗坏血酸酯的合成及细胞中SVCTs成像分析. 第二十届全国色谱学术报告会及仪器展览会null. 2015, http://ir.rcees.ac.cn/handle/311016/33393.
[133] Li, Zheng, Gu, TianPeng, Weber, Alain R, Shen, JiaZhen, Li, BinZhong, Xie, ZhiGuo, Yin, Ruichuan, Guo, Fan, Liu, Xiaomeng, Tang, Fuchou, Wang, Hailin, Schaer, Primo, Xu, GuoLiang. Gadd45a promotes DNA demethylation through TDG. NUCLEIC ACIDS RESEARCH[J]. 2015, 43(8): 3986-3997, [134] Yin, Ruichuan, Mo, Jiezhen, Lu, Meiling, Wang, Hailin. Detection of Human Urinary 5-Hydroxymethylcytosine by Stable Isotope Dilution HPLC-MS/MS Analysis. ANALYTICAL CHEMISTRY[J]. 2015, 87(3): 1846-1852, http://dx.doi.org/10.1021/ac5038895.
[135] 李翠平, 汪海林. 量子点结合毛细管电泳-激光诱导荧光检测DNA氧化损伤. 中国化学会第29届学术年会——第20分会:环境与健康null. 2014, http://ir.rcees.ac.cn/handle/311016/24899.
[136] 莫杰珍, 尹瑞川, 汪海林. 5-甲基胞嘧啶及其氧化产物高灵敏分析方法发展. 第十届全国生物医药色谱及相关技术学术交流会null. 2014, http://ir.rcees.ac.cn/handle/311016/24924.
[137] Song, Maoyong, Liang, Dong, Liang, Yong, Chen, Minjie, Wang, Fengbang, Wang, Hailin, Jiang, Guibin. Assessing developmental toxicity and estrogenic activity of halogenated bisphenol A on zebrafish (Danio rerio). CHEMOSPHERE[J]. 2014, 112(1): 275-281, http://dx.doi.org/10.1016/j.chemosphere.2014.04.084.
[138] Wang, Hailin, Tang, Haoqing, Liu, Zhaotie, Zhang, Xin, Hao, Zhengping, Liu, Zhongwen. Removal of cobalt(II) ion from aqueous solution by chitosan-montmorillonite. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2014, 26(9): 1879-1884, http://dx.doi.org/10.1016/j.jes.2014.06.021.
[139] 汪海林, 刘胜权, 赵柏林, 章大鹏. 毛细管电泳-单分子成像分析揭示等速电泳分离机理. 第十届全国生物医药色谱及相关技术学术交流会null. 2014, http://ir.rcees.ac.cn/handle/311016/24939.
[140] 赵超, 赵柏林, 李翠平, 尹瑞川, 汪海林. 硼酸介导的聚合酶链反应检测基因组DNA中的5-羟甲基胞嘧啶. 中国化学会第29届学术年会——第03分会:分析可视化及交叉学科新方法null. 2014, http://ir.rcees.ac.cn/handle/311016/24967.
[141] 尹瑞川, 黄华, 李翠平, 赵超, 汪海林. 维生素C调控Tet酶介导的DNA羟甲基化与去甲基化. 中国化学会第29届学术年会——第02分会:分离分析及微、纳流控新方法null. 2014, http://ir.rcees.ac.cn/handle/311016/24955.
[142] Zhao, Bailin, Yang, Ying, Wang, Xiaoli, Chong, Zechen, Yin, Ruichuan, Song, ShuHui, Zhao, Chao, Li, Cuiping, Huang, Hua, Sun, BaoFa, Wu, Danni, Jin, KangXuan, Song, Maoyong, Zhu, BenZhan, Jiang, Guibin, Danielsen, Jannie M Rendtlew, Xu, GuoLiang, Yang, YunGui, Wang, Hailin. Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism. NUCLEIC ACIDS RESEARCH[J]. 2014, 42(3): 1593-1605, http://www.irgrid.ac.cn/handle/1471x/936521.
[143] Lee, HyunWook, Wang, HsiangTsui, Weng, Maowen, Hu, Yu, Chen, Weisheng, Chou, David, Liu, Yan, Donin, Nicholas, Huang, William C, Lepor, Herbert, Wu, XueRu, Wang, Hailin, Beland, Frederick A, Tang, Moonshong. Acrolein- and 4-Aminobiphenyl-DNA adducts in human bladder mucosa and tumor tissue and their mutagenicity in human urothelial cells. ONCOTARGET[J]. 2014, 5(11): 3526-3540, http://www.irgrid.ac.cn/handle/1471x/936387.
[144] 钟上伟, 邹丹丹, 赵柏林, 尹瑞川, 赵超, 章大鹏, 李向军, 汪海林. DNA-蛋白质复合物的自由溶液电泳迁移行为. 第十届全国生物医药色谱及相关技术学术交流会null. 2014, http://ir.rcees.ac.cn/handle/311016/24969.
[145] 邹丹丹, 王晓利, 汪海林. DNA甲基化结合蛋白. 环境化学[J]. 2014, 33(10): 1672-1680, http://hjhx.rcees.ac.cn/article/doi/10.7524/j.issn.0254-6108.2014.10.021.
[146] Wang, Hailin, Tang, Haoqing, Liu, Zhaotie, Zhang, Xin, Hao, Zhengping, Liu, Zhongwen. Removal of cobalt(II) ion from aqueous solution by chitosan-montmorillonite. JOURNALOFENVIRONMENTALSCIENCESCHINA[J]. 2014, 26(9): 1879-1884, http://dx.doi.org/10.1016/j.jes.2014.06.021.
[147] 张宁, 尹瑞川, 黄华, 张维冰, 汪海林. 稳定同位素内标超高效液相色谱串联质谱法测定人体细胞中乙醛-DNA加合物的含量. 第十届全国生物医药色谱及相关技术学术交流会null. 2014, http://ir.rcees.ac.cn/handle/311016/24961.
[148] Zhao, Chao, Wang, Hailin, Zhao, Bailin, Li, Cuiping, Yin, Ruichuan, Song, Maoyong, Liu, Baodong, Liu, Zhen, Jiang, Guibin. Boronic acid-mediated polymerase chain reaction for gene- and fragment-specific detection of 5-hydroxymethylcytosine. NUCLEIC ACIDS RESEARCH[J]. 2014, 42(9): http://www.irgrid.ac.cn/handle/1471x/936401.
[149] 刘保东, 李翠平, 尹瑞川, 黄华, 汪海林. (15)~N_5标记的腺嘌呤脱氧核苷在mESC中的代谢研究. 中国化学会第29届学术年会——第20分会:环境与健康null. 2014, http://ir.rcees.ac.cn/handle/311016/24907.
[150] Zou, Dandan, Zhang, Dapeng, Liu, Shengquan, Zhao, Bailin, Wang, Hailin. Interplay of Binding Stoichiometry and Recognition Specificity for the Interaction of MBD2b Protein and Methylated DNA Revealed by Affinity Capillary Electrophoresis Coupled with Laser-Induced Fluorescence Analysis. ANALYTICAL CHEMISTRY[J]. 2014, 86(3): 1775-1782, http://www.irgrid.ac.cn/handle/1471x/936470.
[151] 吴丹妮, 李翠平, 黄华, 张宁, 汪海林. 离子对色谱法测定ATP含量. 中国化学会第29届学术年会——第20分会:环境与健康null. 2014, http://ir.rcees.ac.cn/handle/311016/24943.
[152] Yin, Ruichuan, Liu, Shengquan, Zhao, Chao, Lu, Meiling, Tang, Moonshong, Wang, Hailin. An Ammonium Bicarbonate-Enhanced Stable Isotope Dilution UHPLC-MS/MS Method for Sensitive and Accurate Quantification of Acrolein-DNA Adducts in Human Leukocytes. ANALYTICAL CHEMISTRY[J]. 2013, 85(6): 3190-3197, http://www.irgrid.ac.cn/handle/1471x/844429.
[153] Yin, Ruichuan, Zhang, Dapeng, Song, Yuling, Zhu, BenZhan, Wang, Hailin. Potent DNA damage by polyhalogenated quinones and H2O2 via a metal-independent and Intercalation-enhanced oxidation mechanism. SCIENTIFIC REPORTS[J]. 2013, 3: http://dx.doi.org/10.1038/srep01269.
[154] Agbo, Stanley O, Lemmetyinen, Juha, Keinanen, Markku, KeskiSaari, Santa, Akkanen, Jarkko, Leppanen, Matti T, Wang, Zhixin, Wang, Hailin, Price, David A, Kukkonen, Jussi V K. Response of Lumbriculus variegatus transcriptome and metabolites to model chemical contaminants. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY[J]. 2013, 157(2): 183-191, http://dx.doi.org/10.1016/j.cbpc.2012.11.005.
[155] Song, Maoyong, Zeng, Luzhe, Yuan, Shaopeng, Yin, Junfa, Wang, Hailin, Jiang, Guibin. Study of cytotoxic effects of single-walled carbon nanotubes functionalized with different chemical groups on human MCF7 cells. CHEMOSPHERE[J]. 2013, 92(5): 576-582, http://dx.doi.org/10.1016/j.chemosphere.2013.03.058.
[156] Liu, Shengquan, Zhao, Bailin, Zhang, Dapeng, Li, Cuiping, Wang, Hailin. Imaging of Nonuniform Motion of Single DNA Molecules Reveals the Kinetics of Varying-Field Isotachophoresis. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2013, 135(12): 4644-4647, https://www.webofscience.com/wos/woscc/full-record/WOS:000317032000018.
[157] Zhao Chao, Wang Hailin. The Progress on Sequencing and Detection of Hydroxymethylated DNA. ACTA CHIMICA SINICA[J]. 2013, 71(1): 26-35, https://www.webofscience.com/wos/woscc/full-record/WOS:000315605300002.
[158] 赵超, 汪海林. 5-羟甲基胞嘧啶探针的制备. 第七届全国环境化学学术大会null. 2013, http://ir.rcees.ac.cn/handle/311016/29535.
[159] Yin, Ruichuan, Mao, ShiQing, Zhao, Bailin, Chong, Zechen, Yang, Ying, Zhao, Chao, Zhang, Dapeng, Huang, Hua, Gao, Juan, Li, Zheng, Jiao, Yan, Li, Cuiping, Liu, Shengquan, Wu, Danni, Gu, Weikuan, Yang, YunGui, Xu, GuoLiang, Wang, Hailin. Ascorbic Acid Enhances Tet-Mediated 5-Methylcytosine Oxidation and Promotes DNA Demethylation in Mammals. JOURNALOFTHEAMERICANCHEMICALSOCIETY[J]. 2013, 135(28): 10396-10403, http://dx.doi.org/10.1021/ja4028346.
[160] 赵超, 汪海林. 硫代磷酸寡核苷酸的修饰位点测定. 第七届全国环境化学学术大会null. 2013, http://ir.rcees.ac.cn/handle/311016/29579.
[161] Zhang, Xin, Dou, Guangyu, Wang, Zhuo, Li, Li, Wang, Yufei, Wang, Hailin, Hao, Zhengping. Selective catalytic oxidation of H2S over iron oxide supported on alumina-intercalated Laponite clay catalysts. JOURNAL OF HAZARDOUS MATERIALS[J]. 2013, 260: 104-111, http://dx.doi.org/10.1016/j.jhazmat.2013.05.008.
[162] Wang, Zhuo, Ma, Chunyan, Wang, Hailin, Liu, Zonghuai, Hao, Zhengping. Facilely synthesized Fe2O3-graphene nanocomposite as novel electrode materials for supercapacitors with high performance. JOURNAL OF ALLOYS AND COMPOUNDS[J]. 2013, 552(1): 486-491, http://www.irgrid.ac.cn/handle/1471x/844507.
[163] Song, Maoyong, Zeng, Luzhe, Hong, Xianjun, Meng, Zihui, Yin, Junfa, Wang, Hailin, Liang, Yong, Jiang, Guibin. Polyvinyl Pyrrolidone Promotes DNA Cleavage by a ROS-Independent and Depurination Mechanism. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2013, 47(6): 2886-2891, http://www.irgrid.ac.cn/handle/1471x/844430.
[164] Hailin Wang. Potent DNA damage by polyhalogenated quinones and H₂O₂ via a metal-independent and Intercalation-enhanced oxidation mechanism.. Scientific Reports. 2013, [165] Li, Tiepeng, Wang, Zhixin, Zhao, Yun, He, Wei, An, Lili, Liu, Shengquan, Liu, Yuheng, Wang, Hailin, Hang, Haiying. Checkpoint protein Rad9 plays an important role in nucleotide excision repair. DNA REPAIR[J]. 2013, 12(4): 284-292, http://dx.doi.org/10.1016/j.dnarep.2013.01.006.
[166] 李翠平, 汪海林. 毛细管电泳-激光诱导荧光高灵敏检测苯并(a)芘-DNA加合物. 第七届全国环境化学学术大会null. 2013, http://ir.rcees.ac.cn/handle/311016/29582.
[167] Zhang, Dapeng, Zhao, Qiang, Zhao, Bailin, Wang, Hailin. Fluorescence Anisotropy Reduction of Allosteric Aptamer for Sensitive and Specific Protein Signaling. ANALYTICAL CHEMISTRY[J]. 2012, 84(7): 3070-3074, http://www.irgrid.ac.cn/handle/1471x/901126.
[168] Wang, Hailin, Tian, Hua, Hao, Zhengping. Study of DDT and its derivatives DDD, DDE adsorption and degradation over Fe-SBA-15 at low temperature. ENVIRONMENTAL SCIENCES & ECOLOGY[J]. 2012, 24(3): 536-540, http://lib.cqvip.com/Qikan/Article/Detail?id=41272426.
[169] 汪海林, 章大鹏. 单核苷水平核酸适配体与蛋白质相互作用分析. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/31986.
[170] 宋茂勇, 曾鲁哲, 汪海林. 富勒烯纳米粒子与生物大分子的相互作用及毒性研究. 第七次全国分析毒理学大会暨第四届分析毒理专业委员会第二次会议null. 2012, http://ir.rcees.ac.cn/handle/311016/32008.
[171] Zhao, Chao, Yin, Ruichuan, Yin, Junfa, Zhang, Dapeng, Wang, Hailin. Capillary Monolithic Bioreactor of Immobilized Snake Venom Phosphodiesterase for Mass Spectrometry Based Oligodeoxynucleotide Sequencing. ANALYTICAL CHEMISTRY[J]. 2012, 84(2): 1157-1164, http://www.irgrid.ac.cn/handle/1471x/901142.
[172] 刘胜权, 李翠平, 章大鹏, 赵柏林, 汪海林. 毛细管等速电泳聚焦与高灵敏DNA损伤分析. 全国生物医药色谱及相关技术学术交流会null. 2012, http://ir.rcees.ac.cn/handle/311016/32038.
[173] 章大鹏, 赵柏林, 赵强, 汪海林. 基于荧光各向异性降低适配体特异性检测目标蛋白. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/32023.
[174] Zhang, Dapeng, Shen, Hujun, Li, Guohui, Zhao, Bailin, Yu, Anchi, Zhao, Qiang, Wang, Hailin. Specific and Sensitive Fluorescence Anisotropy Sensing of Guanine-Quadruplex Structures via a Photoinduced Electron Transfer Mechanism. ANALYTICAL CHEMISTRY[J]. 2012, 84(18): 8088-8094, http://www.irgrid.ac.cn/handle/1471x/901101.
[175] Zhang, Min, Zhou, Ying, Li, Tao, Wang, Hailin, Cheng, Fang, Zhou, Yafeng, Bi, Lijun, Zhang, Xian-En. MutL associates with Escherichia coli RecA and inhibits its ATPase activity. BIOCHEMISTRY & MOLECULAR BIOLOGY; BIOPHYSICS[J]. 2012, 517(2): 98-103, http://www.irgrid.ac.cn/handle/1471x/756864.
[176] Chen, Zhilan, Lu, Meiling, Zou, Dandan, Wang, Hailin. An E. coli SOS-EGFP biosensor for fast and sensitive detection of DNA damaging agents. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2012, 24(3): 541-549, http://lib.cqvip.com/Qikan/Article/Detail?id=41272427.
[177] 赵超, 尹瑞川, 尹俊发, 章大鹏, 汪海林. 基于整体柱微酶反应器的DNA测序方法研究. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/32024.
[178] 尹俊发, 王智鑫, 宋茂勇, 赵超, 汪海林. 分子印迹纳米材料用于BPDE-DNA加合物的高灵敏检测. 全国生物医药色谱及相关技术学术交流会null. 2012, http://ir.rcees.ac.cn/handle/311016/32005.
[179] 宋茂勇, 汪海林. 富勒烯纳米尺寸-毒理学效应的研究. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/32007.
[180] Wang Hailin, Tian Hua, Hao Zhengping. Study of DDT and its derivatives DDD, DDE adsorption and degradation over Fe-SBA-15 at low temperature. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA[J]. 2012, 24(3): 536-540, http://lib.cqvip.com/Qikan/Article/Detail?id=41272426.
[181] Chen Zhilan, Lu Meiling, Zou Dandan, Wang Hailin. An E. coli SOS-EGFP biosensor for fast and sensitive detection of DNA damaging agents. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA[J]. 2012, 24(3): 541-549, http://lib.cqvip.com/Qikan/Article/Detail?id=41272427.
[182] Hailin Wang. Size-dependent toxicity of nano-C60 aggregates: More sensitive indication by apoptosis-related Bax translocation in cultured human cells.. Environm. Sci. & Technol.. 2012, [183] 邹丹丹, 汪海林. 基于DNA 甲基化结合蛋白MBD的甲基化分析. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/32140.
[184] Zhang, Min, Zhou, Ying, Li, Tao, Wang, Hailin, Cheng, Fang, Zhou, Yafeng, Bi, Lijun, Zhang, XianEn. MutL associates with Escherichia coli RecA and inhibits its ATPase activity. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS[J]. 2012, 517(2): 98-103, http://www.irgrid.ac.cn/handle/1471x/756864.
[185] 李文静, 尹瑞川, 汪海林. UPLC-MS/MS快速检测五种与细菌能量代谢有关的物质. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/31975.
[186] 李翠平, 汪海林. 高灵敏的量子点介导的毛细管电泳DNA分离分析. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/32010.
[187] Song, Maoyong, Yuan, Shaopeng, Yin, Junfa, Wang, Xiaoli, Meng, Zihui, Wang, Hailin, Jiang, Guibin. Size-Dependent Toxicity of Nano-C-60 Aggregates: More Sensitive Indication by Apoptosis-Related Bax Translocation in Cultured Human Cell. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2012, 46(6): 3457-3464, http://www.irgrid.ac.cn/handle/1471x/901133.
[188] Wang, Hailin, Tian, Hua, Hao, Zhengping. Study of DDT and its derivatives DDD, DDE adsorption and degradation over Fe-SBA-15 at low temperature. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2012, 24(3): 536-540, http://dx.doi.org/10.1016/S1001-0742(11)60800-0.
[189] 曾鲁哲, 宋茂勇, 汪海林. 三种碳纳米材料的细胞毒性研究. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/32049.
[190] 赵柏林, 章大鹏, 邹丹丹, 汪海林. E.coli RecA蛋白在ssDNA上的协同组装及其调节. 中国化学会第28届学术年会null. 2012, http://ir.rcees.ac.cn/handle/311016/31970.
[191] Chen, Zhilan, Lu, Meiling, Zhuang, Guoqiang, Wang, Hailin. Enhanced Bacterial Biosensor for Fast and Sensitive Detection of Oxidatively DNA Damaging Agents. ANALYTICAL CHEMISTRY[J]. 2011, 83(9): 3248-3251, http://dx.doi.org/10.1021/ac200426x.
[192] Ma, Chunyan, Wang, Donghui, Xue, Wenjuan, Dou, Baojuan, Wang, Hailin, Hao, Zhengping. Investigation of Formaldehyde Oxidation over Co3O4-CeO2 and Au/Co3O4-CeO2 Catalysts at Room Temperature: Effective Removal and Determination of Reaction Mechanism. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2011, 45(8): 3628-3634, https://www.webofscience.com/wos/woscc/full-record/WOS:000289341300062.
[193] Dou, Baojuan, Li, Jinjun, Wang, Yufei, Wang, Hailin, Ma, Chunyan, Hao, Zhengping. Adsorption and desorption performance of benzene over hierarchically structured carbon-silica aerogel composites. JOURNAL OF HAZARDOUS MATERIALS[J]. 2011, 196(*): 194-200, http://dx.doi.org/10.1016/j.jhazmat.2011.09.019.
[194] 赵柏林, 汪海林. ATP调节大肠杆菌RecA组装. 第六届全国环境化学学术大会论文集null. 2011, 749-, http://ir.rcees.ac.cn/handle/311016/5574.
[195] 尹瑞川, 汪海林. 丙烯醛-DNA加合物的研究进展. 环境化学[J]. 2011, 30(1): 179-188, http://hjhx.rcees.ac.cn/article/id/hjhx_333.
[196] 宋玉玲, 吕美玲, 汪海林. 基质辅助激光解析电离-飞行时间质谱分析寡核苷酸G-四链体. 中国科学:化学[J]. 2011, 41(1): 74-81, http://lib.cqvip.com/Qikan/Article/Detail?id=36426420.
[197] Xiaoli Wang, Yongshan Suo, Ruichuan Yin, Heqing Shen, Hailin Wang. Ultra-performance liquid chromatography/tandem mass spectrometry for accurate quantification of global DNA methylation in human sperms. JOURNAL OF CHROMATOGRAPHY B. 2011, 1647-1652, http://dx.doi.org/10.1016/j.jchromb.2011.04.002.
[198] Zhang, Dapeng, Lu, Meiling, Wang, Hailin. Fluorescence Anisotropy Analysis for Mapping Aptamer-Protein Interaction at the Single Nucleotide Level. JOURNALOFTHEAMERICANCHEMICALSOCIETY[J]. 2011, 133(24): 9188-9191, https://www.webofscience.com/wos/woscc/full-record/WOS:000291915100015.
[199] Yin, Junfa, Meng, Zihui, Zhu, Yishan, Song, Maoyong, Wang, Hailin. Dummy molecularly imprinted polymer for selective screening of trace bisphenols in river water. ANALYTICAL METHODS[J]. 2011, 3(1): 173-180, https://www.webofscience.com/wos/woscc/full-record/WOS:000287294200024.
[200] Yin, Junfa, Cui, Yue, Yang, Gengliang, Wang, Hailin. Molecularly imprinted nanotubes for enantioselective drug delivery and controlled release. CHEMICALCOMMUNICATIONS[J]. 2010, 46(41): 7688-7690, http://www.irgrid.ac.cn/handle/1471x/964241.
[201] Li, Tao, Zhang, Dapeng, Luo, Wenru, Lu, Meiling, Wang, Zhixin, Song, Yuling, Wang, Hailin. Metal Cation Mediated-Capillary Electrophoresis of Nucleic Acids. ANALYTICAL CHEMISTRY[J]. 2010, 82(2): 487-490, http://www.irgrid.ac.cn/handle/1471x/964236.
[202] Song Maoyong, Jiang Guibin, Yin Junfa, Wang Hailin. Inhibition of polymerase activity by pristine fullerene nanoparticles can be mitigated by abundant proteins. CHEMICAL COMMUNICATIONS[J]. 2010, 46(9): 1404-1406, http://www.irgrid.ac.cn/handle/1471x/964224.
[203] Wang, Zhixin, Wang, Xiaoli, Liu, Shengquan, Yin, Junfa, Wang, Hailin. Fluorescently Imaged Particle Counting Immunoassay for Sensitive Detection of DNA Modifications. ANALYTICAL CHEMISTRY[J]. 2010, 82(23): 9901-9908, http://www.irgrid.ac.cn/handle/1471x/964213.
[204] Lu, Meiling, Mani, Rajam S, KarimiBusheri, Feridoun, Fanta, Mesfin, Wang, Hailin, Litchfeld, David W, Weinfeld, Michael. Independent mechanisms of stimulation of polynucleotide kinase/phosphatase by phosphorylated and non-phosphorylated XRCC1. NUCLEIC ACIDS RESEARCH[J]. 2010, 38(2): 510-521, [205] Feng, Feng, Wang, Xiaoli, Yuan, Hancheng, Wang, Hailin. Ultra-performance liquid chromatography-tandem mass spectrometry for rapid and highly sensitive analysis of stereoisomers of benzoapyrene diol epoxide-DNA adducts. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2009, 877(22): 2104-2112, http://dx.doi.org/10.1016/j.jchromb.2009.05.054.
[206] Wang HaiLin, Zhou YuMin, Zhuang YaHui, Wang XiaoKe, Hao ZhengPing. Characterization of PM2.5/PM2.5-10 and source tracking in the juncture belt between urban and rural areas of Beijing. CHINESE SCIENCE BULLETIN[J]. 2009, 54(14): 2506-2515, http://lib.cqvip.com/Qikan/Article/Detail?id=30866927.
[207] 汪海林, 王智鑫, 李涛等. 基于毛细管电泳-激光诱导荧光的高灵敏核酸分析及其应用. 第十七届全国色谱学术报告会论文集null. 2009, 204-205, http://ir.rcees.ac.cn/handle/311016/5780.
[208] Hailin Wang. Fluorescence polarization combined capillary electrophoresis immunoassay for rapid and sensitive detection of genomic DNA methylation. Anal. Chem.. 2009, [209] Gao Haiyan, Guo Fangqiu, Feng Feng, Yin Junfa, Song Maoyong, Wang Hailin. Improved preparation and identification of aristolochic acid-DNA adducts by solid-phase extraction with liquid chromatography-tandem mass spectrometry. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2009, 21(12): 1769-1776, http://lib.cqvip.com/Qikan/Article/Detail?id=32308045.
[210] Wang, Zhixin, Lu, Meiling, Wang, Xiaoli, Yin, Ruichuan, Song, Yuling, Le, X Chris, Wang, Hailin. Quantum Dots Enhanced Ultrasensitive Detection of DNA Adducts. ANALYTICAL CHEMISTRY[J]. 2009, 81(24): 10285-10289, http://www.irgrid.ac.cn/handle/1471x/971935.
[211] Li, Tao, Wang, Hailin. Organic Osmolyte Mediated Kinetic Capillary Electrophoresis for Study of Protein-DNA Interactions. ANALYTICALCHEMISTRY[J]. 2009, 81(5): 1988-1995, http://www.irgrid.ac.cn/handle/1471x/971919.
[212] Wang, Hailin, Lu, Meiling, Tang, MoonShong, Van Houten, Bennett, Ross, J B Alexander, Weinfeld, Michael, Le, X Chris. DNA wrapping is required for DNA damage recognition in the Escherichia coli DNA nucleotide excision repair pathway. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2009, 106(31): 12849-12854, http://www.irgrid.ac.cn/handle/1471x/971862.
[213] 汪海林, 吕美玲, 王智鑫, 李涛, 王超, 尹瑞川. 高灵敏毛细管电泳-激光诱导荧光偏振分析及其在环境健康研究中的应用. 生物物理学报[J]. 2009, 151-152, http://ir.rcees.ac.cn/handle/311016/5350.
[214] 吕美玲, 汪海林, Michael Weinfeld. XRCC1磷酸化增强核酸单链断裂修复中聚核苷酸激酶的活性. 生物物理学报[J]. 2009, 158-159, http://ir.rcees.ac.cn/handle/311016/5345.
[215] Wang, Chao, Feng, Feng, Wang, Zhixin, Li, Tao, Le, X Chris, Wang, Hailin. Synthesis and Characterization of DNA Fluorescent Probes Containing a Single Site-Specific Stereoisomer of anti-Benzoapyrene Diol Epoxide-N-2-dG. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2009, 22(4): 676-682, http://www.irgrid.ac.cn/handle/1471x/971949.
[216] 李涛, 赛道建, 汪海林, 张月侠, 宋茂勇. 适配体的筛选及在生命分析化学中的应用. 生物技术[J]. 2009, 19(5): 90-94, http://lib.cqvip.com/Qikan/Article/Detail?id=31880727.
[217] Gao Haiyan, Guo Fangqiu, Feng Feng, Yin Junfa, Song Maoyong, Wang Hailin. Improved preparation and identification of aristolochic acid-DNA adducts by solid-phase extraction with liquid chromatography-tandem mass spectrometry. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA[J]. 2009, 21(12): 1769-1776, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000273080800022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[218] 尹瑞川, 汪海林. 亲合毛细管电泳-激光诱导荧光法检测丙烯醛-DNA加合物. 第五届全国环境化学大会会议论文集null. 2008, 462-, http://ir.rcees.ac.cn/handle/311016/5878.
[219] Wang HaiLin, Zhuang Yahui, Hao ZhengPing, Cao MeiQiu, Zhong JinXian, Wang XiaoKe, Oanh, Nguyen Thi Kim. Polycyclic aromatic hydrocarbons from rural household biomass burning in a typical Chinese village. SCIENCE IN CHINA SERIES D-EARTH SCIENCES[J]. 2008, 51(7): 1013-1020, http://www.irgrid.ac.cn/handle/1471x/972130.
[220] Zhao, Lijuan, Zhang, FuShen, Hao, Zhengping, Wang, Hailin. Levels of polycyclic aromatic hydrocarbons in different types of hospital waste incinerator ashes. SCIENCE OF THE TOTAL ENVIRONMENT[J]. 2008, 397(1-3): 24-30, http://dx.doi.org/10.1016/j.scitotenv.2008.02.040.
[221] Wang Hailin, Zhuang Yahui, Wang Ying, Sun Yele, Yuan Hui, Zhuang Guoshun, Hao Zhengping. Long-term monitoring and source apportionment of PM2.5/PM10 in Beijing, China. JOURNAL OF ENVIRONMENTAL SCIENCES[J]. 2008, 20(11): 1323-1327, http://lib.cqvip.com/Qikan/Article/Detail?id=1000588758.
[222] Wang HaiLin, Zhuang Yahui, Hao ZhengPing, Cao MeiQiu, Zhong JinXian, Wang XiaoKe, Oanh, Nguyen Thi Kim. Polycyclic aromatic hydrocarbons from rural household biomass burning in a typical Chinese village. SCIENCE IN CHINA SERIES D-EARTH SCIENCES[J]. 2008, 51(7): 1013-1020, http://www.irgrid.ac.cn/handle/1471x/972130.
[223] Lu, Meiling, Wang, Hailin, Wang, Zhongwen, Li, XingFang, Le, X Chris. Identification of reactive cysteines in a protein using arsenic labeling and collision-induced dissociation tandem mass spectrometry. JOURNAL OF PROTEOME RESEARCH[J]. 2008, 7(8): 3080-3090, http://www.irgrid.ac.cn/handle/1471x/972017.
[224] Wang, Hai Lin, Hao, Zheng Ping, Zhuang, Ya Hui, Wang, Wei, Liu, Xiao Yu. Characterization of inorganic components of size-segregated particles in the flue gas of a coal-fired power plant. ENERGY & FUELS[J]. 2008, 22(3): 1636-1640, http://www.irgrid.ac.cn/handle/1471x/972134.
[225] Wang Hailin, Zhuang Yahui, Wang Ying, Sun Yele, Yuan Hui, Zhuang Guoshun, Hao Zhengping. Long-term monitoring and source apportionment of PM2.5/PM10 in Beijing, China. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA[J]. 2008, 20(11): 1323-1327, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000260879500007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[226] Wang, Hailin, Cheng, Jie, Li, Jinjun, Hao, Zhengping. Comparison of hydrolysis and oxidation reactions of carbonyl sulfide on particle matter. ASIA-PACIFIC JOURNAL OF CHEMICAL ENGINEERING[J]. 2008, 3(5): 509-513, http://www.irgrid.ac.cn/handle/1471x/972123.
[227] Hailin Wang. A microdialysis sampling method for evaluation of binding kinetics of small molecules to macromolecules. Anal. Chem.. 2008, 
发表著作
(1) 现代毒理学, A Textbook of Mordern Toxicology, 中国科学出版社, 2011-06, 第 2 作者

科研活动

   
科研项目
( 1 ) 国家杰出青年基金, 主持, 国家级, 2012-01--2015-12
( 2 ) 毛细管电泳-双光子荧光偏振单分子检测装置, 主持, 国家级, 2014-01--2017-12
( 3 ) DNA损伤分析方法与生物效应研究及专用仪器开发”, 主持, 国家级, 2012-01--2015-12
( 4 ) 针对蛋白质-核酸相互作用研究的单分子荧光偏振分析方法学与技术, 主持, 国家级, 2015-01--2019-12
( 5 ) 污染物与生物大分子的交互作用, 主持, 部委级, 2014-06--2018-12

指导学生

已指导学生

刘淑芳  博士研究生  083001-环境科学  

王智鑫  博士研究生  083001-环境科学  

冯峰  博士研究生  083001-环境科学  

李涛  博士研究生  083001-环境科学  

王超  硕士研究生  083001-环境科学  

陈芝兰  博士研究生  083001-环境科学  

宋玉玲  硕士研究生  083001-环境科学  

王晓利  博士研究生  083001-环境科学  

章大鹏  博士研究生  083001-环境科学  

刘胜权  博士研究生  083001-环境科学  

赵超  博士研究生  083001-环境科学  

尹瑞川  博士研究生  083001-环境科学  

李文静  硕士研究生  083001-环境科学  

邹丹丹  博士研究生  083001-环境科学  

李翠平  博士研究生  083001-环境科学  

赵柏林  博士研究生  070302-分析化学  

黄华  博士研究生  083001-环境科学  

刘保东  博士研究生  083001-环境科学  

刘晓玲  博士研究生  070302-分析化学  

刘迪  硕士研究生  077601-环境科学  

吴丹妮  博士研究生  083001-环境科学  

赖玮毅  博士研究生  083001-环境科学  

朱会宇  博士研究生  083001-环境科学  

现指导学生

袁征  博士研究生  070302-分析化学  

陈政  博士研究生  083001-环境科学  

任云  博士研究生  083001-环境科学  

莫杰珍  博士研究生  070302-分析化学  

李瑶  硕士研究生  071010-生物化学与分子生物学  

刘艳  博士研究生  071007-遗传学  

景昶衡  硕士研究生  077601-环境科学  

余方志  博士研究生  070302-分析化学  

孙境蔚  硕士研究生  071010-生物化学与分子生物学  

郑婧  硕士研究生  070302-分析化学  

吕聪  博士研究生  070302-分析化学