General

Dr. Xiao-Ya Chen, Professor, Academician, Institute of Plant Physiology and Ecology, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences.


Research Areas

Dr. Xiao-Ya Chen is interested in plant secondary metabolism (especially sesquiterpene biosynthesis in cotton and selected medicinal plants), plant-insect interactions, RNAi technology for pest control, trichome and cotton fiber development.


Education

1978.02 - 1982.02.  Department of Biology, Nanjing University,China, B.Sc.

1982.09 - 1985.10.  Department of Botany, University of Reading,U.K., Ph.D.


Experience

1985.12 - 1991.10.  Department of Biology, University of Nanjing, lecturer and associate professor.

1991.10 - 1992.09.  Institute of Botany, Tübingen University,Germany, visiting scientist

1992.09- 1994.10 . Department of Medicinal Chemistry and Pharmacognosy, Purdue University,USA,  postdoctoral scientist

1994.10 -                 National Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese  Academy of Sciences.


Publications

   
Papers
(1) Core cis-element variation confers subgenome-biased expression of a transcription factor that functions in cotton fiber elongation, New Phytologist, 2018, 通讯作者
(2) Characterization of gossypol biosynthetic pathway, Proc Natl Acad Sci U S A, 2018, 通讯作者
(3) Jasmonate response decay and defense metabolite accumulation contributes to age-regulated dynamics of plant insect resistance, Nature Communications, 2017, 通讯作者
(4) Arabidopsis transcription factors SPL1 and SPL12 confer plant thermotolerance at reproductive stage, Molecular Plant, 2017, 通讯作者
(5) Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase, Biochemical Journal, 2017, 通讯作者
(6) Genetic basis for glandular trichome formation in cotton, Nature Communications, 2016, 通讯作者
(7) Targeting insect mitochondrial complex I for plant protection, Plant Biotechnology Journal, 2016, 通讯作者
(8) Small interfering RNAs from bidirectional transcripts of GhMML3_A12 regulate cotton fiber development, New Phytologist, 2016, 通讯作者
(9) Down-regulation of Rubisco Activity by Non-enzymatic Acetylation of RbcL, Molecular Plant, 2016, 通讯作者
(10) Progressive regulation of sesquiterpene biosynthesis in Arabidopsis and Patchouli (Pogostemon cablin) by the miR156-targeted SPL transcription factors, Molecular Plant, 2015, 通讯作者
(11) Gossypium barbadense genome sequence provides insight into the evolution of extra-long staple fiber and specialized metabolites, Scientific Reports, 2015, 通讯作者
(12) Control of cotton fibre elongation by a homeodomain transcription factor GhHOX3, Nature Communications, 2014, 通讯作者
(13) Interaction between two timing MicroRNAs controls trichome distribution in Arabidopsis, PLoS Genet , 2014, 通讯作者
(14) Rational engineering plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency, Biochemical Journal, 2013, 通讯作者
(15) A Cotton BURP Domain Protein Interacts With α-Expansin and Their Co-Expression Promotes Plant Growth and Fruit Production, Molecular Plant, 2013, 通讯作者
(16) Transcriptome analysis of medicinal plant Salvia miltiorrhiza and identification of genes related to tanshinone biosynthesis, PLoS One, 2013, 通讯作者
(17) Isolation and Characterization of Terpene Synthases in Cotton (Gossypium hirsutum), Phytochemistry, 2013, 通讯作者
(18) Cysteine protease enhances plant-mediated bollworm RNA interference, Plant Mol Biol. , 2013, 通讯作者
(19) CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts., Proc Natl Acad Sci U S A., 2013, 通讯作者
(20) Warm temperatures induce transgenerational epigenetic release of RNA silencing by inhibiting siRNA biogenesis in Arabidopsis., Proc Natl Acad Sci U S A., 2013, 通讯作者
(21) Arabidopsis MYC2 Interacts with DELLA Proteins in Regulating Sesquiterpene Synthase Gene Expression,  Plant Cell, 2012, 通讯作者
(22) The Jasmonate-Responsive AP2/ERF Transcription Factors AaERF1 and AaERF2 Positively Regulate Artemisinin Biosynthesis in Artemisia annua, Molecular Plant, 2012, 通讯作者
(23) Temporal control of trichome distribution by miR156-targeted SPL genes in Arabidopsis thaliana., Plant Cell, 2010, 通讯作者
(24) Silencing a cotton bollworm P450 gene by plant-mediated RNAi impairs larval tolerance to gossypol, Nature Biotechnology, 2007, 通讯作者
(25) Gene expression and metabolite profiles of cotton fiber during cell elongation and secondary cell wall synthesis, Cell Research, 2007, 通讯作者
(26) Control of Root Cap Formation by MicroRNA-Targeted Auxin Response Factors in Arabidopsis, Plant Cell, 2005, 通讯作者
(27) Control of Plant Trichome Development by a Cotton Fiber MYB Gene, Plant Cell, 2004, 通讯作者
(28) Ex planta phytoremediation of trichlorophenol and phenolic allelochemicals via an engineered secretory laccase., Nature Biotechnology, 2004, 通讯作者


Students

已指导学生

王佳伟  博士研究生  071007-遗传学  

骆萍  博士研究生  071007-遗传学  

关雪莹  博士研究生  071007-遗传学  

朱勇清  博士研究生  071007-遗传学  

周向军  博士研究生  071007-遗传学  

李春红  博士研究生  071007-遗传学  

王国栋  博士研究生  071007-遗传学  

余歆  博士研究生  071001-植物学  

许燕华  博士研究生  071007-遗传学  

缑金营  博士研究生  071007-遗传学  

骆斌  博士研究生  071007-遗传学  

李前进  博士研究生  071007-遗传学  

杨长青  博士研究生  071007-遗传学  

于楠  博士研究生  071007-遗传学  

徐冰  博士研究生  071007-遗传学  

洪高洁  博士研究生  071007-遗传学  

蔡文娟  博士研究生  071007-遗传学  

陶晓园  博士研究生  071007-遗传学  

薛学义  博士研究生  071007-遗传学  

李建戌  博士研究生  071007-遗传学  

高翔  博士研究生  071007-遗传学  

于宗霞  博士研究生  071007-遗传学  

单淳敏  博士研究生  071007-遗传学  

阮菊新  博士研究生  071007-遗传学  

朝鲁门  博士研究生  071007-遗传学  

陈殿阳  博士研究生  071007-遗传学  

洪惠  博士研究生  071007-遗传学  

赵波  博士研究生  071007-遗传学  

张秀芳  博士研究生  071007-遗传学  

崔文瑞  硕士研究生  071007-遗传学  

现指导学生

黄金泉  博士研究生  071007-遗传学  

刘尧倩  博士研究生  071007-遗传学  

李辰意  博士研究生  071007-遗传学  

陈芳艳  博士研究生  071007-遗传学  

茹扎·阿哈提  硕士研究生  071007-遗传学  

宋维萌  博士研究生  071007-遗传学  

于诚慧  硕士研究生  071007-遗传学  

曹俊峰  博士研究生  071007-遗传学  

陈春雨  博士研究生  071007-遗传学  

陈雪莹  硕士研究生  071007-遗传学  

陈秋逸  硕士研究生  071001-植物学  

郭晓祥  硕士研究生  071001-植物学