基本信息
张雁云 男 博导 上海交通大学医学院
电子邮件: yyzhang@sibs.ac.cn
通信地址: 上海市徐汇区岳阳路320号
邮政编码:
电子邮件: yyzhang@sibs.ac.cn
通信地址: 上海市徐汇区岳阳路320号
邮政编码:
招生信息
招生专业
071009-细胞生物学086000-生物与医药
招生方向
新型免疫生物学靶向药物及治疗干细胞免疫学肿瘤免疫学
教育背景
2000-09--2001-07 日本东京大学医学部 博士后1997-09--2000-07 日本东京大学医学部 医学博士、Ph. D.1990-09--1993-07 苏州医学院生物技术研究所 免疫学硕士1978-09--1983-07 苏州医学院医学系临床医学专业 医学学士
工作经历
工作简历
2002-09~现在, 中国科学院上海生命科学研究院/上海交通大学医学院健康科学研究所, 研究员 副所长2002-09~现在, 上海交通大学医学院上海市免疫学研究所, 教授2001-07~2003-07,日本东京大学医学部, 研究员2000-09~2001-07,日本东京大学医学部, 博士后1997-09~2000-07,日本东京大学医学部, 医学博士、Ph. D.1996-09~1998-09,日本东京大学医学部分子医学研究室, 客座研究员1990-09~1996-07,苏州医学院组织学胚胎学实验室, 主任1990-09~1993-07,苏州医学院生物技术研究所, 免疫学硕士1983-09~1996-06,苏州医学院组织学胚胎学教研室、免疫学教研室, 助教、讲师1978-09~1983-07,苏州医学院医学系临床医学专业, 医学学士
教授课程
免疫生物学
出版信息
发表论文
(1) Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host disease., Blood, 2011, 通讯作者(2) Impairment of Regulatory Capacity of CD4+CD25+ Regulatory T Cells Mediated by Dendritic Cell Polarization and Hyperthyroidism in Graves’ Disease., The Journal of Immunology, 2011, 通讯作者(3) 18β-glycyrrhetinic acid ameliorated Propionibacterium acnes-induced acute liver injury through inhibition of MIP-1α., The Journal of Biological Chemistry, 2010, 通讯作者(4) Genetic ablation of steroid receptor coactivator-3 promotes PPAR-beta-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis., Glia, 2010, 通讯作者(5) Therapeutic effect of MIP-1alpha-recruited dendritic cells on preestablished solid and metastatic tumors., Cancer Letters, 2010, 通讯作者(6) Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node etastasis in human colorectal cancer., BMC Cancer, 2010, 通讯作者(7) Role of dendritic cells and chemokines in acute graft-versus-host disease., Frontiers in bioscience, 2008, 通讯作者(8) Suppressor of cytokine signaling-1, a possible cause for regulatory T cells in hepatitis., Hepatology, 2008, 通讯作者(9) MIP-3(alpha) and MIP-1(alpha) rapidly mobilize dendritic cell precursors into the peripheral blood, Journal of Leukocyte Biology, 2008, 通讯作者(10) A new approach of blocking alloreactive T cell-mediated GVHD by in vivo administration of anti-CXCR3 neutralizing antibody., The Journal of Immunology, 2008, 通讯作者(11) Recombination of CXCR4, VEGF, and MMP-9 predicting lymph node metastasis in human breast cancer. , Cancer Letters, 2007, 通讯作者(12) Synovial autoreactive T cells in rheumatoid arthritis resist indoleamine IDO-mediated inhibition., The Journal of Immunology, 2006, 通讯作者(13) Mobilization of dendritic cell precursors into the circulation by administration of MIP-1? in mice., Journal of the National Cancer Institute, 2004, 第 1 作者(14) Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules., International Immunology, 2004, 第 3 作者(15) Pivotal role of CCL25 (TECK)/CCR9 in the formation of gut cryptopatches and consequent appearance of intestinal intraepithelial T lymphocytes., International Immunology, 2002, 第 3 作者(16) Pivotal role of dendritic cell-derived CXCL 10 in the retention of T helper cell 1 lymphocytes in the secondary lymph nodes., Journal of Experimental Medicine, 2002, 第 3 作者(17) Identification of CD8+CD11c- phenotype-negative cells in the spleen as committed precursor of CD8+ dendritic cells., Blood, 2002, 第 2 作者(18) Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease., Journal of Experimental Medicine, 2001, 第 3 作者(19) mpairment of Lymphopoiesis and myelopoiesis in mice reconstituted with bone marrow-hematopoietic progenitor cells expressing SDF-1-Intrakine., Blood, 2000, 第 2 作者(20) Development of dendritic cells in vitro from murine fetal liver-derived lineage phenotype-negative c-kit+ hematopoietic progenitor cells. , Blood, 2000, 第 1 作者(21) Chemotactic response toward chemokines and its regulation by transforming growth factor-β1 of bone marrow hematopoietic progenitor cell-derived different subset of dendritic cells., Blood, 1999, 第 2 作者(22) Transforming growth factor-polarizes murine hematopoietic progenitor cells to generate Langerhans cell-like dendritic cells through monocyte/macrophage differentiation pathway., Blood, 1999, 第 1 作者(23) Bifurcated dendritic cell differentiation in vitro from murine lineage phenotype-negative c-kit+ bone marrow hematopoietic progenitor cells., Blood, 1998, 第 1 作者
科研活动
科研项目
( 1 ) GPR120作为乳腺癌耐药检测标志及其作用机制研究, 负责人, 地方任务, 2015-09--2018-08( 2 ) 间充质干细胞治疗肝衰竭的细胞与分子机制研究, 负责人, 国家任务, 2012-01--2016-12( 3 ) 组蛋白乙酰化/去乙酰化表观调控效应型记忆CD8+T细胞及其防治GVHD 的研究, 负责人, 国家任务, 2014-01--2017-12