基本信息
张伟  男  博导  国家纳米科学中心
电子邮件: zhangw@nanoctr.cn
通信地址: 北京市海淀区中关村北一条11号
邮政编码:

招生信息

   
招生专业
080502-材料学
招生方向
生物材料

教育背景

2008-07--国家纳米科学中心   研究员
1999-09--2004-07   清华大学   学士、硕士、博士

工作经历

   
工作简历
2008-07~现在, 国家纳米科学中心, 研究员
2006-07~2008-06,深圳清华大学研究院, 助理研究员
2004-07~2006-06,美国纽约州立大学布法罗分校, 博士后
1999-09~2004-07,清华大学, 学士、硕士、博士
社会兼职
2014-01-01-今,Journal of Nanoscience Letters编委,
2012-12-13-2012-12-18,中国材料大会2012生物材料分会主席,

教授课程

“纳米生物学”中文

专利与奖励

   
专利成果
( 1 ) 一种免疫层析试纸条、检测方法及应用, 2017, 第 3 作者, 专利号: 201310607244.1

( 2 ) 一种金纳米颗粒在制备抗凝血剂或抗血小板剂中的应用, 2017, 第 4 作者, 专利号: 201410231394.1

( 3 ) 用于化学发光检测的微流控芯片成像仪器和系统, 2017, 第 3 作者, 专利号: 201310503116.2

( 4 ) 条码化层析试纸条的制备方法、其检测装置及应用, 2017, 第 2 作者, 专利号: 201710073098.7

( 5 ) 一种化学发光-胶体金免疫层析试纸条的构建及应用, 2017, 第 5 作者, 专利号: 201410325350.5

( 6 ) 一种检测甲流抗原的胶体金免疫层析试纸条及检测甲流抗原的方法, 2016, 第 3 作者, 专利号: 201410363297.8

( 7 ) 检测IgM抗体的胶体金试纸条及其试纸卡、试剂盒, 2016, 第 3 作者, 专利号: 201520925242.1

( 8 ) 检测IgM抗体的胶体金试纸条及试纸卡、制备和检测方法, 2016, 第 3 作者, 专利号: 201510801825.8

( 9 ) 可在高倍物镜下直接观测的动脉血管模拟微流控装置, 2015, 第 5 作者, 专利号: 201410054147.9

( 10 ) 一种动脉血管模拟微流控装置及其应用, 2015, 第 3 作者, 专利号: 201110404504.6

( 11 ) 利用高压静电纺丝翻模在材料表面得到微纳米结构的方法, 2015, 第 4 作者, 专利号: 201110101498.7

( 12 ) 条形码微流控芯片及其用途, 2015, 第 2 作者, 专利号: 201210467165.0

( 13 ) 具有微流通道的水凝胶及其制备方法和应用, 2015, 第 4 作者, 专利号: 201210086433.4

( 14 ) 一种免疫层析试纸条、检测方法及应用, 2013, 第 3 作者, 专利号: 201310607244.1

( 15 ) 用于化学发光检测的微流控芯片成像仪器和系统, 2013, 第 3 作者, 专利号: 201310503116.2

( 16 ) 用于环介导等温扩增的微流控芯片、其制备方法和应用, 2013, 第 3 作者, 专利号: 201310503118.1

( 17 ) 一种使用四苯乙烯衍生物检测乳制品中酪蛋白的方法, 2012, 第 4 作者, 专利号: 201210306050.3

( 18 ) 多层管状结构细胞培养支架及其制备方法和用途, 2011, 第 4 作者, 专利号: 201110439414.0

( 19 ) 利用高压静电纺丝翻模在材料表面得到微纳米结构的方法, 2010, 第 4 作者, 专利号: 201110101498.7

( 20 ) 一种用于微流通道的除气泡装置, 2010, 第 3 作者, 专利号: 201010256931.X

( 21 ) 氨基嘧啶修饰的金纳米颗粒及其制备方法和用途, 2010, 第 5 作者, 专利号: 2010101191760.0

( 22 ) 微流控免疫印迹芯片、其制备方法及用途, 2009, 第 2 作者, 专利号: 200910241223.6

出版信息

   
发表论文
(1) A strategy for rapid construction of blood vessel-like structures with complex cell alignments, Macromol Biosci, 2018, 第 8 作者
(2) In Vitro Evaluation of Essential Mechanical Properties and Cell Behaviors of a Novel Polylactic-co-Glycolic Acid (PLGA)-Based Tubular Scaffold for Small-Diameter Vascular Tissue Engineering, Polymers, 2017, 第 4 作者
(3) Self-adjusting, polymeric multilayered roll that can keep the shapes of the blood vessel scaffolds during biodegradation, Adv Mater, 2017, 第 5 作者
(4) Skiving stacked sheets of paper into test paper for rapid and multiplexed assay, Sci Adv, 2017, 第 2 作者
(5) Inkjet-printed barcodes for a rapid and multiplexed paper-based assay compatible with mobile devices, Lab Chip, 2017, 第 2 作者
(6) Detection of Nanomolar Level of Total Cr [(III) and (VI)] by Functionalized Gold Nanoparticles and a Smartphone with the Assistance of Theoretical Calculation Models, Nanoscale, 2015, 第 4 作者
(7) Multiplexed microfluidic blotting of proteins and nucleic acids by parallel, serpentine microchannels, Lab Chip, 2015, 第 4 作者
(8) Investigation of Tumor Cell Behaviors on a Vascular Microenvironment-Mimicking Microfluidic Chip, Sci Rep-UK, 2015, 第 4 作者
(9) Barcoded Microchips For Biomolecular Assays, Anal Chem, 2015, 通讯作者
(10) Organs on microfluidic chips: A mini review, China Chem, 2014, 第 3 作者
(11) Antithrombotic functions of small molecule capped gold nanoparticles, Nanoscale, 2014, 通讯作者
(12) Assembly of Functional Three-Dimensional Neuronal Networks on a Microchip, Small, 2014, 第 4 作者
(13) A peptide-based nanofibrous hydrogel as a promising DNA nanovector for optimizing the efficacy of HIV vaccine, Nano lett, 2014, 第 4 作者
(14) Facile, One-Pot Synthesis, and Antibacterial Activity of Mesoporous Silica Nanoparticles Decorated with Well-Dispersed Silver Nanoparticles, ACS Appl Mater Inter, 2014, 通讯作者
(15) Screening Reactive Oxygen Species Scavenging Properties of Platinum Nanoparticles on a Microfluidic chip, Biofabrication, 2014, 第 4 作者
(16) Tissue-specific Mechanical and Geometrical Control of Cell Viability and Actin Cytoskeleton Alignment, Sci Rep-UK, 2014, 第 4 作者
(17) Culturing Primary Human Osteoblasts on Electrospun Poly(lactic-co-glycolic acid) and Poly(lactic-co-glycolic acid)/Nanohydroxyapatite Scaffolds for Bone Tissue Engineering, ACS Appl Mater Interfaces, 2013, 第 4 作者
(18) Stress-Induced Self-Assembly of Complex Three Dimensional Structures by Elastic Membranes, Small, 2013, 第 4 作者
(19) Engineering a 3D vascular network in hydrogel for mimicking a nephron, Lab Chip, 2013, 通讯作者
(20) Preparation and characterization of radially porous silica and the core-shell structure, Chem J Chinese U, 2012, 通讯作者
(21) The molecular mechanism of action of bactericidal gold nanoparticles on Escherichia coli, Biomaterials, 2012, 通讯作者
(22) Electrospun Fiber Template for Replica Molding of Microtopographical Neural Growth Guidance, Small, 2012, 通讯作者
(23) Mussel-Inspired Anchoring for Patterning Cells Using Polydopamine, Langmuir, 2012, 通讯作者
(24) Accelerating microfluidic immunoassays on filter membranes by applying vacuum, Biomed Microdevices, 2012, 通讯作者
(25) A strategy for depositing different types of cells in three dimensions to mimic tubular structures in tissues, Adv Mater, 2012, 通讯作者
(26) A microfluidic flow-stretch chip for investigating blood vessel biomechanics, Lab Chip, 2012, 第 4 作者
(27) Fluid flow stress induced contraction and re-spread of mesenchymal stem cells: a microfluidic study, Integr Biol, 2012, 第 3 作者
(28) A rapid screening method for wound dressing by cell-on-a-chip device, Adv Health Mater, 2012, 通讯作者
(29) Microfluidic assay without blocking for rapid HIV screening and confirmation, Biomed Microdevices, 2012, 通讯作者
(30) Precise Control of Cell Adhesion by Combination of Surface Chemistry and Soft Lithography, Adv Health Mater, accepted, 2012, 第 2 作者
(31)  A strategy for the construction of controlled, three-dimensional, multilayered, tissue-like structures, Adv Funct Mater, 2012, 通讯作者
(32) Co-cultured endometrial stromal cells and peritoneal mesothelial cells for an in vitro model of endometriosis, Integr. Biol, 2012, 通讯作者
(33) Rapid casein quantification in milk powder with aggregation induced emission character of tetraphenylethene derivative, Analyst, 2012, 第 4 作者
(34) Microfluidics for manipulating cells, Small, 2012, 第 4 作者
(35) 5. Resettable, multi-readout logic gates based on controllably reversible aggregation of gold nanoparticles, Angew. Chem. Int. Ed, 2011, 通讯作者
(36) Self-organizing circuit assembly through spatiotemporally coordinated neuronal migration within geometric constraints, PLoS ONE, 2011, 通讯作者
(37) A microchip-based model wound with multiple types of cells, Lab Chip, 2011, 通讯作者
(38) Recent progress in the application of microfluidic systems and gold nanoparticles in immunoassays, Science China-Chemistry, 2011, 通讯作者
(39) MCM-41 single crystal of hexagonal circular bicone with pseudo-singular surface and morphogenesis, Crystengcomm, 2011, 通讯作者
(40) 9. In vitro model on glass surfaces for complex interactions between different types of cells, Langmuir, 2010, 通讯作者
(41) 10. Highly Sensitive, Colorimetric Detection of Mercury(II) in Aqueous Media by Quaternary Ammonium Group-Capped Gold Nanoparticles at Room Temperature, Anal. Chem, 2010, 第 4 作者
(42) 11. A Strategy for the Modification of Electrospun Fibers that Allows Diverse Functional Groups for Biomolecular Entrapment,  Chem. Mater, 2010, 通讯作者
(43) 12. A simple design in PDMS-based microfluidic channels that rids bubbles in long-term on-chip culture of mammalian cells, Lab Chip, 2010, 通讯作者
(44) A novel approach to prepare hybrid AlPO4/nano-carbon (graphite-like) (AlPO4/NCG) material from layer-structured AlPO4/Benzylamine, Mater Lett, 2010, 第 3 作者
(45) 13. Biomimetic Collagen Nanofibrous Materials for Bone Tissue Engineering, Adv. Eng. Mater, 2010, 通讯作者
(46) 14. A general approach for patterning multiple types of cells using holey PDMS membranes and microfluidic channels, Adv. Funct. Mater, 2010, 通讯作者
(47) 18. Adsorbed Tween 80 is unique in its ability to improve the stability of gold nanoparticles in solutions of biomolecules, Nanoscale, 2010, 第 3 作者
(48) Development of neurons on micropatterns reveals that growth cone responds to a sharp change of concentration of laminin, Electrophoresis, 2010, 通讯作者
(49) Conformation change of collagen during the initial stage of biomineralization of calcium phosphate, J Mater Chem, 2008, 第 4 作者
(50) Inhibition of calcium oxalate monohydrate crystallization by the combination of citrate and osteopontin, J Cryst Growth, 2006, 第 2 作者
(51) Silk fibroin regulated mineralization of hydroxyapatite nanocrystals, J Cryst Growth, 2004, 通讯作者
(52) Kinetic study on collagen mineralization by ultraviolet absorption spectra, Spectrosc Spect Anal, 2004, 第 2 作者
(53) Study of the nucleation sites in collagen mineralization, Spectrosc Spect Anal, 2004, 第 2 作者
(54) Hierarchically biomimetic bone scaffold materials: Nano-HA /collagen /PLA composite,  JOURNAL OF BIOMEDICAL MATERIALS , 2004, 第 3 作者
(55) A phenomenon of negative peak appeared in kinetic ultraviolet absorb curve of initial biomineralization, Chem J Chinese U, 2003, 第 2 作者
(56) Nucleation sites of calcium phosphate crystals during collagen mineralization, JOURNAL OF THE AMERICAN CERAMIC SOCIETY, 2003, 第 1 作者
(57) Hierarchical self-assembly of nano-fibrils in mineralized collagen, CHEMISTRY OF MATERIALS , 2003, 第 1 作者
(58) Formation of calcium phosphate/collagen composites through mineralization of collagen matrix, JOURNAL OF BIOMEDICAL MATERIALS , 2000, 第 3 作者

科研活动

   
科研项目
( 1 ) 微流控技术研究流体剪切应力对骨组织细胞生物矿化过程的影响, 负责人, 国家任务, 2010-01--2012-12
( 2 ) 促进产业升级的纳米材料技术及应用, 参与, 国家任务, 2012-01--2014-12
( 3 ) 针对生物标志物检测的低成本检测系统的研制, 参与, 国家任务, 2012-11--2015-12
( 4 ) 三维结构上细胞图案化组织工程血管的研究, 负责人, 国家任务, 2014-01--2017-12
( 5 ) 与重大慢性疾病诊治相关的纳米技术基础研究, 参与, 中国科学院计划, 2009-01--2013-12
( 6 ) 基于纳米技术的神经信息检测相关基础研究, 参与, 国家任务, 2011-01--2015-12
( 7 ) 基于微流控技术的呼吸道病原体多指标快速检测的临床前研究, 负责人, 地方任务, 2013-01--2015-12
( 8 ) 用于肿瘤标志物免疫检测的微流控芯片及配套仪器研发, 负责人, 地方任务, 2014-01--2015-12
( 9 ) 光控纳米组装体的制备及其在神经细胞靶向调控中的应用, 参与, 国家任务, 2017-07--2022-06