基本信息
蒋宇 女 硕导 上海陶宇晟生物技术有限责任公司
电子邮件: biojiangyu@139.com
通信地址: 枫林路300号
邮政编码:
电子邮件: biojiangyu@139.com
通信地址: 枫林路300号
邮政编码:
招生信息
招生专业
071005-微生物学086000-生物与医药
招生方向
代谢工程与合成生物学
教育背景
2001-09--2007-03 江南大学 博士1997-09--2001-06 江南大学 学士
工作经历
工作简历
2009-11~现在, 中国科学院植物生理生态研究所, 副研究员2009-07~2009-10,中国科学院上海生命科学研究院植物生理生态研究所, 助理研究员2007-03~2009-06,中国科学院上海生命科学研究院植物生理生态研究所, 博士后2001-09~2007-03,江南大学, 博士1997-09~2001-06,江南大学, 学士
专利与奖励
奖励信息
(1) 中国科学院科技促进发展奖, 一等奖, 部委级, 2016(2) 上海市科技进步奖, 一等奖, 省级, 2015(3) SA-SIBS 2010 Young Faculty Award, 研究所(学校), 2010
专利成果
( 1 ) 一种用于棒状杆菌基因组编辑的CRISPR系统, 2017, 第 2 作者, 专利号: 201710009784.8( 2 ) 乙醇生产工艺与发酵微生物, 2016, 第 3 作者, 专利号: PCT/CN2014087191( 3 ) L-苏氨酸基因工程生产菌, 2015, 第 2 作者, 专利号: CN201510684017.8( 4 ) L-异亮氨酸基因工程生产菌, 2015, 第 2 作者, 专利号: CN201510684287.9( 5 ) 一种酶法制备他汀类化合物中间体的方法, 2015, 第 5 作者, 专利号: 201510209354.1( 6 ) L-苏氨酸基因工程生产菌, 2015, 第 2 作者, 专利号: 201510199036.1( 7 ) L-赖氨酸基因工程生产菌, 2015, 第 2 作者, 专利号: 201510185330.7( 8 ) 含解毒酶活性且发酵残渣可用于饲料的微生物, 2014, 第 3 作者, 专利号: 201410740316.4
出版信息
发表论文
(1) Production of beta-carotene by expressing a heterologous multifunctional carotene synthase in Yarrowia lipolytica, Biotechnol Lett, 2017, 第 5 作者(2) Iterative integration of multiple-copy pathway genes in Yarrowia lipolytica for heterologous beta-carotene production, Metab. Eng, 2017, 第 7 作者(3) CRISPR-Cpf1 assistedgenome editingof Corynebacterium glutamicum, Nat Commun, 2017, 第 1 作者(4) Enhanced solvent production by metabolic engineering of a twin-clostridial consortium, Metab Eng, 2017, 第 6 作者(5) Efficient multi-enzyme-catalyzed CDP-choline production driven by an ATP donor module, Appl Microbiol Biotechnol, 2017, 第 8 作者(6) A recyclable biotransformation system for L-2-aminobutyric acid production based on immobilized enzyme technology, Biotechnol Lett, 2016, 第 2 作者(7) Complete genome sequence of nucleoside producing strain Corynebacterium stationis ATCC 6872, J Biotechnol, 2016, 第 3 作者(8) CRISPR-based genome editing and expression control systems in Clostridium acetobutylicum and Clostridium beijerinckii, Biotechnol J, 2016, 第 10 作者(9) Tailor-made biocatalysts enzymes for the fine chemical industry in China, Biotechnol J, 2016, 第 1 作者(10) Enzymatic Production of Glutathione by Bifunctional gamma-Glutamylcysteine Synthetase/Glutathione Synthetase Coupled with In Vitro Acetate Kinase-Based ATP Generation, Appl Biochem Biotechnol, 2016, 第 1 作者(11) Erratum for Jiang et al., Multigene Editing in the Escherichia coli Genome via the CRISPR-Cas9 System, Appl Environ Microbiol, 2016, 第 1 作者(12) Multiplex gene editing of the Yarrowia lipolytica genome using the CRISPR-Cas9 system, J Ind Microbiol Biotechnol, 2016, 第 7 作者(13) Synergy between methylerythritol phosphate pathway and mevalonate, Metab Eng, 2016, 第 3 作者(14) Tailor-made biocatylysts enzymes for the fine chemical industry in China, Biotechnology Journal, 2016, 第 1 作者(15) Enzymatic Production of Glutathione by Bifunctional gamma-Glutamylcysteine Synthetase/Glutathione Synthetase Coupled with In Vitro Acetate Kinase-Based ATP Generation, Applied Biochemistry and Biotechnology, 2016, 第 1 作者(16) I-SceI-mediated scarless gene modification via allelic exchange in Clostridium, J Microbiol Methods, 2015, 第 3 作者(17) A recyclable biotransformation system for L-2-aminobutyric acid production based on immobilized enzyme technology, Biotechnol Lett, 2015, 第 2 作者(18) Current status and prospects of industrial bio-production of n-butanol in China, Biotechnol Adv, 2015, 第 1 作者(19) High-efficiency scarless genetic modification in Escherichia coli by using lambda red recombination and I-SceI cleavage, Appl Environ Microbiol, 2014, 第 4 作者(20) Exploiting Issatchenkia orientalis SD108 for succinic acid production, Microb Cell Fact, 2014, 第 3 作者(21) A one-pot system for production of L-2-aminobutyric acid from L-threonine by L-threonine deaminase and a NADH-regeneration system based on L-leucine dehydrogenase and formate dehydrogenase, Biotechnol Lett, 2014, 第 2 作者(22) One-step integration of multiple genes into the oleaginous yeast Yarrowia lipolytica, Biotechnol Lett, 2014, 第 6 作者(23) Improvement of solvent production from xylose mother liquor by engineering the xylose metabolic pathway in Clostridium acetobutylicum EA 2018, Appl Biochem Biotechnol, 2013, 第 4 作者(24) Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism, Biochem J, 2013, 第 6 作者(25) Construction of fast xylose-fermenting yeast based on industrial ethanol-producing diploid Saccharomyces cerevisiae by rational design and adaptive evolution, BMC Biotechnol, 2013, 第 5 作者(26) Metabolic engineering of D-xylose pathway in Clostridium beijerinckii to optimize solvent production from xylose mother liquid, Metab Eng, 2012, 第 3 作者
科研活动
科研项目
( 1 ) 纤维素丁醇联产化学品关键技术研究与 产业化, 负责人, 国家任务, 2012-01--2014-12( 2 ) 长三角生物医药技术集聚转化基地, 负责人, 中国科学院计划, 2013-01--2015-12( 3 ) 异戊二烯的生物合成研究, 负责人, 中国科学院计划, 2013-01--2015-12( 4 ) 生物元件的鉴定组装及标准化, 负责人, 国家任务, 2012-01--2016-12( 5 ) 梭菌产丁醇途径重构和调试, 负责人, 国家任务, 2013-01--2016-12