基本信息
崔峰  女  博导  中国科学院动物研究所
电子邮件: cuif@ioz.ac.cn
通信地址: 北京朝阳区北辰西路1号院5号
邮政编码: 100101

招生信息

   
招生专业
0710Z1-基因组学
071010-生物化学与分子生物学
招生方向
媒介昆虫与病毒基因组学

教育背景

2003-09--2006-06   中科院动物所   博士

工作经历

   
工作简历
2017-01~现在, 中国科学院动物研究所, 研究员
2009-01~现在, 中科院动物所, 副研
2006-07~现在, 中科院动物所, 助研
2003-09~2006-06,中科院动物所, 博士
社会兼职
2022-10-01-2027-10-01,中国昆虫学会副秘书长, 副秘书长
2022-10-01-2027-10-01,昆虫比较免疫与互作专业委员会副主任, 副主任
2022-09-30-2027-09-30,中国昆虫学会常务理事, 常务理事
2017-09-30-2022-10-01,昆虫比较免疫与互作专业委员会主任, 主任
2017-09-30-2022-10-01,昆虫基因组学专业委员会委员, 委员
2017-09-29-2022-10-01,中国昆虫学会理事, 理事
2017-01-01-2020-01-01,北京农药学会理事, 理事
2013-05-31-2017-10-01,中国昆虫学会农业昆虫专业委员会委员, 委员

教授课程

媒介生物学

专利与奖励

   
专利成果
( 1 ) 一种控制水稻条纹病毒传播的方法, 2019, 第 1 作者, 专利号: CN106906218B

( 2 ) 辅助鉴定库蚊携带的羧酸酯酶等位基因的专用引物及其应用, 2012, 第 1 作者, 专利号: CN102485908A

( 3 ) 检测水体中是否存在杀虫剂及杀虫剂含量范围的试剂盒, 2012, 第 2 作者, 专利号: CN102305790A

( 4 ) 一种降解六六六的菌株及其应用, 2012, 第 5 作者, 专利号: CN102757906A

( 5 ) 检测库蚊乙酰胆碱酯酶G119S突变的试剂盒, 2012, 第 3 作者, 专利号: CN102485909A

( 6 ) 应用羧酸酯酶显色法快速检测抗性蚊虫的试剂盒, 2012, 第 1 作者, 专利号: CN102486459A

( 7 ) 一种六六六降解菌及其在降解六六六中的应用, 2010, 第 3 作者, 专利号: CN101805714A

出版信息

   
发表论文
(1) c-Jun regulates flotillin 2 transcription to benefit viral accumulation in insect vectors, Insect Biochemistry and Molecular Biology, 2023, 通讯作者
(2) Molecular basis of methyl-salicylate mediated plant airborne defence., Nature, 2023, 第11作者
(3) Association of virome dynamics with mosquito species and environmental factors, MICROBIOME, 2023, 第 1 作者
(4) Flotillin 2 Facilitates the Infection of a Plant Virus in the Gut of Insect Vector, JOURNAL OF VIROLOGY, 2022, 通讯作者
(5) The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication, The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication, PROTEIN & CELL, 2022, 通讯作者
(6) Key role of exportin 6 in exosome-mediated viral transmission from insect vectors to plants, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 通讯作者
(7) Alternative splicing landscape of small brown planthopper and different response of JNK2 isoforms to rice stripe virus infection, Journal of Virology, 2022, 通讯作者
(8) Interaction between endogenous microRNAs and virus-derived small RNAs controls viral replication in insect vectors., PLOS PATHOGENS, 2022, 通讯作者
(9) Mutation in the RNA-Dependent RNA Polymerase of a Symbiotic Virus Is Associated With the Adaptability of the Viral Host, FRONTIERS IN MICROBIOLOGY, 2022, 通讯作者
(10) Regulation of RNA Interference Pathways in the Insect Vector Laodelphax striatellus by Viral Proteins of Rice Stripe Virus, VIRUSES, 2021, 第 5 作者
(11) COORDINATION BETWEEN TERMINAL VARIATION OF THE VIRAL GENOME AND INSECT MICRORNAS REGULATES RICE STRIPE VIRUS REPLICATION IN INSECT VECTORS, PLOS PATHOGENS, 2021, 通讯作者
(12) Characterization of protein-protein interactions between rice viruses and vector insects, CHARACTERIZATION OF PROTEIN-PROTEIN INTERACTIONS BETWEEN RICE VIRUSES AND VECTOR INSECTS, INSECT SCIENCE, 2021, 通讯作者
(13) REGULATION OF RNA INTERFERENCE PATHWAYS IN THE INSECT VECTOR LAODELPHAX STRIATELLUS BY VIRAL PROTEINS OF RICE STRIPE VIRUS, VIRUSES-BASEL, 2021, 通讯作者
(14) A Symbiotic Virus Facilitates Aphid Adaptation to Host Plants by Suppressing Jasmonic Acid Responses, MOLECULAR PLANT-MICROBE INTERACTIONS, 2020, 通讯作者
(15) 植物病媒昆虫的翅型分化, Wing morph differentiation of plant-pathogen borne vector insects, 昆虫学报, 2020, 第 4 作者
(16) Potential functional pathways of plant RNA virus-derived small RNAs in a vector insect, METHODS, 2020, 通讯作者
(17) A Plant Virus Ensures Viral Stability in the Hemolymph of Vector Insects through Suppressing Prophenoloxidase Activation, MBIO, 2020, 通讯作者
(18) Mosquito Diversity and Population Genetic Structure of Six Mosquito Species From Hainan Island, FRONTIERS IN GENETICS, 2020, 通讯作者
(19) Armet, an aphid effector protein, induces pathogen resistance in plants by promoting the accumulation of salicylic acid, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2019, 通讯作者
(20) Immune function of an angiotensin-converting enzyme against Rice stripe virus infection in a vector insect, VIROLOGY, 2019, 通讯作者
(21) Immune responses induced by different genotypes of the disease-specific protein of Rice stripe virus in the vector insect, VIROLOGY, 2019, 通讯作者
(22) Distinct replication and gene expression strategies of the Rice Stripe virus in vector insects and host plants, JOURNAL OF GENERAL VIROLOGY, 2019, 第 5 作者
(23) Evaluation of Rice stripe virus transmission efficiency by quantification of viral load in the saliva of insect vector, PEST MANAGEMENT SCIENCE, 2019, 通讯作者
(24) Rice stripe virus-derived siRNAs play different regulatory roles in rice and in the insect vector Laodelphax striatellus, BMC PLANT BIOLOGY, 2018, 通讯作者
(25) 一株新的致倦库蚊细胞系的建立与鉴定, Establishment and identification of a new cell line from Culex pipiens quinquefasciatus ( Diptera: Culicidae), 昆虫学报, 2018, 第 2 作者
(26) Genomic variations in the 3'-termini of Rice stripe virus in the rotation between vector insect and host plant, NEW PHYTOLOGIST, 2018, 通讯作者
(27) Large-Scale Gene Expression Reveals Different Adaptations of Hyalopterus persikonus to Winter and Summer Host Plants, INSECT SCIENCE, 2017, 通讯作者
(28) Genome sequence of the small brown planthopper, Laodelphax striatellus, GIGASCIENCE, 2017, 通讯作者
(29) Insecticide Resistance Status and Detoxification Enzymes of Wheat Aphids Sitobion avenae and Rhopalosiphum padi, SCIENCE CHINA-LIFE SCIENCES, 2017, 通讯作者
(30) Isolation of Rice Stripe Virus Preparation from Viruliferous Small Brown Planthoppers and Mechanic Inoculation on Rice, BIO-PROTOCOL, 2017, 第 2 作者
(31) The c-Jun N-Terminal Kinase Pathway of a Vector Insect is Activated by Virus Capsid Protein and Promotes Viral Replication, ELIFE, 2017, 通讯作者
(32) Insecticide resistance status and detoxification enzymes of wheat aphids Sitobion avenae and Rhopalosiphum padi, SCIENCE CHINA LIFE SCIENCES, 2017, 第 5 作者
(33) Transcriptomic Responses of Three Aphid Species to Chemical Insecticide Stress, SCIENCE CHINA-LIFE SCIENCES, 2017, 通讯作者
(34) 媒介昆虫与植物病毒互作研究进展, Advances in research on the interaction between insect vectors and plant viruses, 应用昆虫学报, 2017, 第 6 作者
(35) Different pathogenicities of Rice stripe virus from the insect vector and from viruliferous plants, NEW PHYTOLOGIST, 2016, 通讯作者
(36) Organ-Specific Transcriptome Response of the Small Brown Planthopper Toward Rice Stripe Virus, INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2016, 通讯作者
(37) Rice responses and resistance to planthopper-borned viruses at transcriptomic and proteomic levels, Current Issues in Molecular Biology, 2016, 第 1 作者
(38) Rice Responses and Resistance to Planthopper-Borne Viruses at Transcriptomic and Proteomic Levels, CURRENT ISSUES IN MOLECULAR BIOLOGY, 2016, 第 1 作者
(39) Performances of Survival, Feeding Behavior, and Gene Expression in Aphids Reveal Their Different Fitness to Host Alteration, SCIENTIFIC REPORTS, 2016, 通讯作者
(40) Phylogenetic Analysis of the ATP-Binding Cassette Transporter Family in Three Mosquito Species, PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2016, 通讯作者
(41) High expression of a unique aphid protein in the salivary glands of Acyrthosiphon pisum, PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY, 2015, 
(42) Carboxylesterase-Mediated Insecticide Resistance: Quantitative Increase Induces Broader Metabolic Resistance than Qualitative Change, PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2015, 第 1 作者
(43) Over-transcription of genes in a parathion-resistant strain of mosquito Culex pipiens quinquefasciatus, INSECTSCIENCE, 2015, 通讯作者
(44) Armet Is an Effector Protein Mediating Aphid-Plant Interactions, FASEB JOURNAL, 2015, 通讯作者
(45) Angiotensin-Converting Enzymes Modulate Aphid-Plant Interactions, SCIENTIFIC REPORTS, 2015, 通讯作者
(46) Over-transcription of genes in a parathion-resistant strain of mosquito Culex pipiens quinquefasciatus, Over-transcription of genes in a parathion-resistant strain of mosquito Culex pipiens quinquefasciatus, 中国昆虫科学:英文版, 2015, 第 6 作者
(47) The locust genome provides insight into swarm formation and long-distance flight, NATURE COMMUNICATIONS, 2014, 第 8 作者
(48) 致倦库蚊GSTe1和CYP9J40的时空表达特点, Temporal and spatial expression of the GSTe1 and CYP9J40 genes in Culex pipiens quinquefasciatus, 应用昆虫学报, 2014, 第 3 作者
(49) Anoxic Stress and Rapid Cold Hardening Enhance Cold Tolerance of the Migratory Locust, CRYOBIOLOGY, 2014, 
(50) Characterization of an Aphid-Specific,Cysteine-Rich Protein Enriched in Salivary Glands, BIOPHYSICAL CHEMISTRY, 2014, 通讯作者
(51) High-Throughput Genotyping of Single-Nucleotide Polymorphisms in ace-1 Gene of Mosquitoes Using MALDI-TOF Mass Spectrometry, INSECT SCIENCE, 2013, 通讯作者
(52) 两个单点突变对昆虫羧酸酯酶降解马拉硫磷的影响, 昆虫学报, 2013, 第 4 作者
(53) 灰飞虱唾液腺三大解毒酶家族的转录组分析, 昆虫学报, 2013, 第 5 作者
(54) High-throughput genotyping of single-nucleotide polymorphisms in ace-1 gene of mosquitoes using MALDI-TOF mass spectrometry, High-throughput genotyping of single-nucleotide polymorphisms in ace-1 gene of mosquitoes using MALDI-TOF mass spectrometry, 中国昆虫科学:英文版, 2013, 第 7 作者
(55) Altered Immunity in Crowded Locust Reduced Fungal (Metarhizium anisopliae) Pathogenesis, PLOS PATHOGENS, 2013, 第 3 作者
(56) Distribution and Dynamics of Esterase Alleles in Culex pipiens Complex in China, JOURNAL OF ASIA-PACIFIC ENTOMOLOGY, 2013, 第 3 作者
(57) Polymorphism and Methylation of Four Genes Expressed in Salivary Glands of Russian Wheat Aphid (Homoptera: Aphididae), JOURNAL OF ECONOMIC ENTOMOLOGY, 2012, 第 2 作者
(58) Development of a Novel Optical Biosensor for Detection of Organophoshorus Pesticides Based on Methyl Parathion Hydrolase Immobilized by Metal-Chelate Affinity, SENSORS, 2012, 第 3 作者
(59) 湖北省黄州区三带喙库蚊抗药性调查及武昌罗索线虫感染对其影响研究, Resistance of Culex tritaeniorhynchus in Huangzhou district, Huanggang city, Hubei province, China to commonly used insecticides and the potential effect of Romanomermis wuchangensis infection on its insecticide resistance, 中国媒介生物学及控制杂志, 2012, 第 5 作者
(60) Polymorphisms in salivary-gland transcripts of Russian wheat aphid biotypes 1 and 2, Polymorphisms in salivary-gland transcripts of Russian wheat aphid biotypes 1 and 2, 中国昆虫科学:英文版, 2012, 第 1 作者
(61) 蚊虫乙酰胆碱酯酶的真核表达、纯化及活性测定, Expression and purification of acetylcholinesterase from culex by Bac-to-Bac baculovirus system and the activity determination, 华中农业大学学报, 2012, 第 3 作者
(62) Parental phase status affects the cold hardiness of progeny eggs in locusts, FUNCTIONAL ECOLOGY, 2012, 第 3 作者
(63) Identification of resistant carboxylesterase alleles in Culex pipiens complex via PCR-RFLP., PARASITES & VECTORS, 2012, 通讯作者
(64) 抑制性差减杂交技术在蚊虫研究中的应用, Application of suppression subtractive hybridization inmosquito researches, 应用昆虫学报, 2012, 
(65) Transcriptomic and phylogenetic analysis of Culex pipiens quinquefasciatus for three detoxification gene families, BMC GENOMICS, 2012, 通讯作者
(66) Construction of a Genetically Engineered Microorganism that Simultaneously Degrades Organochlorine and Organophosphate Pesticides, APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2012, 第 5 作者
(67) Polymorphisms in salivary-gland transcripts of Russian wheat aphid biotypes 1 and 2, Polymorphisms in salivary-gland transcripts of Russian wheat aphid biotypes 1 and 2, INSECT SCIENCE, 2012, 通讯作者
(68) 蚜虫基因组及功能基因组研究进展, Advances in research on aphid genomics and functional genomics, 应用昆虫学报, 2011, 第 5 作者
(69) 中国媒介蚊虫对有机磷类和拟除虫菊酯类杀虫剂的抗性调查, Investigation of organophosphate and pyrethroid resistance in vector mosquitoes in China, 中国媒介生物学及控制杂志, 2011, 第 2 作者
(70) Correlation between carboxylesterase alleles and insecticide resistance in Culex pipiens complex from China, PARASITES & VECTORS, 2011, 第 5 作者
(71) Correlation between carboxylesterase alleles and insecticide resistance in Culex pipiens complex from China., PARASITES & VECTORS, 2011, 第 5 作者
(72) 致倦库蚊主要组织结构的石蜡切片观察, Histological observation of major structures of the mosquito Culex pipiens quinquefasciatus (Diptera: Culicidae) using paraffin tissue section, 昆虫学报, 2011, 第 5 作者
(73) 酯酶显色法快速检测尖音库蚊对有机磷的抗性, Rapid detection of organophosphate resistance in Culex pipiens complex by acetylcholinesterase staining, 中国媒介生物学及控制杂志, 2011, 第 7 作者
(74) 中国媒介蚊虫对有机氯类和氨基甲酸酯类杀虫剂的抗性调查, Investigation on the resistance of vector mosquitoes to organochlorines and carbamates in China, 中国媒介生物学及控制杂志, 2011, 第 2 作者
(75) 豌豆蚜唾液蛋白家族的克隆及在不同发育阶段的表达, Cloning and expression profiling of a saliva protein family at different developmental stages in Acyrthosiphon pisum ( Hemiptera .- Aphididae), 昆虫学报, 2011, 第 8 作者
(76) Two single mutations commonly cause qualitative change of nonspecific carboxylesterases in insects, INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2011, 
(77) 蚊虫杀虫药剂的抗性及防治策略, Insecticide resistance of mosquitoes and control strategies, 中国媒介生物学及控制杂志, 2010, 第 2 作者
(78) Structure, function and applications of insect carboxylesterases evolved for insecticide resistance, Protein and Peptide Letters, 2009, 第 1 作者
(79) 尖音库蚊复组有机磷抗性相关酯酶B2基因杂合型的分子特征, Heterozygous genotypes and molecular characteristics of Organophosphorus resistance associated esterase B2 genes of Culex pipiens complex, 中华预防医学杂志, 2009, 第 5 作者
(80) Structure, function and applications of carboxylesterases from insects for insecticide resistance., PROTEIN AND PEPTIDE LETTERS, 2009, 第 2 作者
(81) Dynamics of esterase alleles in culex pipiens complex mosquitoes in beijing, JOURNAL OF ECONOMIC ENTOMOLOGY, 2008, 第 3 作者
(82) Do mosquitoes acquire organophosphate resistance by functional changes in carboxylesterases?, FASEB JOURNAL, 2007, 第 1 作者
(83) Different Amino-Acid Substitutions Confer Insecticide Resistance Through Acetylcholinesterase 1 Insensitivity in Culex vishnui and Culex tritaeniorhynchus (Diptera: Culicidae) from China, JOURNAL OF MEDICAL ENTOMOLOGY, 2007, 第 3 作者
(84) Genetic differentiation of culex pipiens (diptera : culicidae) in china, BULLETIN OF ENTOMOLOGICAL RESEARCH, 2007, 
(85) Characterization of novel esterases in insecticide-resistant mosquitoes, INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2007, 第 1 作者
(86) 蚊虫抗药性分子机理, The molecular mechanisms of insecticide resistance in mosquitoes., 昆虫知识, 2007, 第 1 作者
(87) 复合PCR—RFLP技术用于尖音库蚊复组抗性相关酯酶基因分子分型, Molecular typing on insecticide resistance-associated esterase genes of Culex pipiens complex by PCR-RFLP techniques, 中国媒介生物学及控制杂志, 2007, 第 5 作者
(88) Filariasis vector in China: insecticide resistance and population structure of mosquito Culex pipiens complex, PEST MANAGEMENT SCIENCE, 2007, 第 1 作者
(89) 杭州市库蚊复组抗性相关酯酶Estβ基因类型和频率及动态分布, Genotypes, allele frequencies and dynamic distribution on resistance-associated esterase genes of Culex pipiens complex in Hangzhou, 中华预防医学杂志, 2007, 第 6 作者
(90) 杭州地区尖音库蚊复合组的抗药性动态, Dynamic of insecticide resistance and genetic diversity of populations in Culex pipiens complex from Hangzhou area., 昆虫知识, 2006, 第 1 作者
(91) Insecticide resistance in vector mosquitoes in China, PEST MANAGEMENT SCIENCE, 2006, 第 1 作者
(92) Recent Emergence of Insensitive Acetylcholinesterase in Chinese Populations of the Mosquito Culex pipiens (Diptera: Culicidae), JOURNAL OF MEDICAL ENTOMOLOGY, 2006, 第 1 作者
(93) Insecticide resistance in Chinese populations of the Culex pipiens complex through esterase overproduction, ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, 2006, 
(94) 不同地理种群尖音库蚊复组杀虫药剂抗性及抗性酯酶, Insecticide Resistance and Overproduced Esterases in Populations Culex pipiens Complex of China, 中国媒介生物学及控制杂志, 2005, 第 1 作者
(95) 被动迁移在抗性进化中的作用, 中国昆虫科学:英文版(1005-295X), 2003, 第 3 作者
(96) Genomic variations in the 3′‐termini of Rice stripe virus in the rotation between vector insect and host plant, THE NEW PHYTOLOGIST, 第 7 作者
发表著作
( 1 ) 生态基因组学, 科学出版社, 2019-09, 第 5 作者
( 2 ) 中国学科发展战略-媒介生物学, 北京:科学出版社, 2021-06, 第 5 作者

科研活动

   
科研项目
( 1 ) 麦蚜杀虫剂抗性机理的基因调控网络研究, 负责人, 国家任务, 2013-01--2016-12
( 2 ) 害虫种群暴发的行为遗传机制, 负责人, 国家任务, 2012-01--2016-08
( 3 ) 重要病媒生物监测和传播相关病原体检测技术研究, 负责人, 国家任务, 2012-01--2015-12
( 4 ) 大豆蚜抗性快速检测试剂盒的研制, 负责人, 国家任务, 2011-01--2015-12
( 5 ) 灰飞虱与水稻条纹叶枯病种间信息流的识别机制, 负责人, 中国科学院计划, 2014-07--2019-06
( 6 ) 唾液腺基因在灰飞虱传播水稻条纹病的作用和机理, 负责人, 国家任务, 2014-01--2018-12
( 7 ) 农作物主要病害发生的分子机理及防控策略, 参与, 中国科学院计划, 2011-01--2014-12
( 8 ) 水稻条纹病毒调控媒介昆虫应激蛋白激酶信号通路的研究, 负责人, 国家任务, 2018-01--2021-12
( 9 ) 影响媒介传播效能的关键生物因子研究, 负责人, 国家任务, 2017-07--2020-06
( 10 ) 新一代RNA干扰防虫技术的开发研究, 负责人, 中国科学院计划, 2020-02--2023-01
( 11 ) 病毒小RNA调控媒介昆虫传播效能的机制研究, 负责人, 中国科学院计划, 2019-09--2024-09
( 12 ) 利用蚜虫共生病毒表达杀虫蛋白的技术研发, 负责人, 中国科学院计划, 2020-11--2025-10
( 13 ) 水稻条纹病毒基因组末端小RNA对病毒复制的调控作用, 负责人, 中国科学院计划, 2021-06--2022-05
( 14 ) 水稻条纹病毒调控媒介昆虫RNAi途径C3PO复合物的功能研究, 负责人, 国家任务, 2023-01--2027-12
( 15 ) 病虫害农作物信号联系机制与诱控新技术和新产品研发, 负责人, 国家任务, 2022-09--2025-12