基本信息
苏枭  男  博导  中国科学院上海免疫与感染研究所
电子邮件: xsu@ips.ac.cn
通信地址: 上海岳阳路320号生命科学大楼B座楼114室
邮政编码: 200031

招生信息

   
招生专业
100102-免疫学
招生方向


出版信息

   
发表论文
[1] Feng, Xintong, Li, Ling, Feng, Jingjing, He, Wei, Li, Na, Shi, Tianyun, Jie, Zhijun, Su, Xiao. Vagal-alpha 7nAChR signaling attenuates allergic asthma responses and facilitates asthma tolerance by regulating inflammatory group 2 innate lymphoid cells. IMMUNOLOGY AND CELL BIOLOGY[J]. 2021, 99(2): 206-222, http://dx.doi.org/10.1111/imcb.12400.
[2] Feng, Xintong, Zhao, Caiqi, Li, Ling, Feng, Jingjing, He, Wei, Shi, Tianyun, Li, Na, Jie, Zhijun, Su, Xiao. iNKT cells with high PLZF expression are recruited into the lung via CCL21-CCR7 signaling to facilitate the development of asthma tolerance in mice. EUROPEAN JOURNAL OF IMMUNOLOGY[J]. 2021, 51(2): 414-432, https://www.webofscience.com/wos/woscc/full-record/WOS:000566347200001.
[3] Gao, Zhaowei, Li, Ling, Huang, Yuanyuan, Zhao, Caiqi, Xue, Shuangjia, Chen, Jie, Yang, Zhongzhou, Xu, Jinfu, Su, Xiao. Vagal-alpha 7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection. ACTA PHARMACOLOGICA SINICA[J]. 2021, 42(10): 1642-1652, http://dx.doi.org/10.1038/s41401-020-00579-z.
[4] Caiqi Zhao, Jie Chen, Lianping Cheng, Kaifeng Xu, Yiyu Yang, Xiao Su. Deficiency of HIF-1α enhances influenza A virus replication by promoting autophagy in alveolar type II epithelial cells. EMERGING MICROBES & INFECTIONS. 2020, 9(1): 691-706, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144238/.
[5] Xiaoyan Chen, Jie Chen, Yuanlin Song, Xiao Su. Vagal α7nAChR signaling regulates α7nAChR + Sca1 + cells during lung injury repair. STEM CELL RESEARCH & THERAPY[J]. 2020, 11(1): 1-13, http://dx.doi.org/10.1186/s13287-020-01892-4.
[6] 苏枭. SARS-CoV-2 viral sepsis: from bedside to bench. Lancet. 2020, [7] 苏枭. Vagal-α7nAChR signaling promotes lung stem cell regeneration via fibroblast growth factor 10 during lung injury repair. Stem Cell Research & Therapy. 2020, [8] Chen, Xiaoyan, Zhao, Caiqi, Zhang, Cuiping, Li, Qingmei, Chen, Jie, Cheng, Lianping, Zhou, Jian, Su, Xiao, Song, Yuanlin. Vagal-alpha 7nAChR signaling promotes lung stem cells regeneration via fibroblast growth factor 10 during lung injury repair. STEM CELL RESEARCH & THERAPY[J]. 2020, 11(1): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000542661700004.
[9] Tao, Rujia, Cao, Weijun, Li, Manhui, Yang, Ling, Dai, Ruoxuan, Luo, Xiaoli, Liu, Yang, Ge, Baoxue, Su, Xiao, Xu, Jinfu. PM2.5 compromises antiviral immunity in influenza infection by inhibiting activation of NLRP3 inflammasome and expression of interferon-beta. MOLECULAR IMMUNOLOGY[J]. 2020, 125: 178-186, http://dx.doi.org/10.1016/j.molimm.2020.07.001.
[10] 陈小燕, 李清梅, 季诗梦, 程婷婷, 周建, 陈翠翠, 苏枭, 宋元林. 干细胞稳态和动员的自主神经调控研究进展. 复旦学报:医学版[J]. 2020, 47(3): 448-455, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFDLAST2020&filename=SHYK202003025&v=MTE2ODBGckNVUjdxZVp1ZHVGeXptV3IzSU5pWFNaYkc0SE5ITXJJOUhZWVI4ZVgxTHV4WVM3RGgxVDNxVHJXTTE=.
[11] Zhao, Caiqi, Chen, Jie, Cheng, Lianping, Xu, Kaifeng, Yang, Yiyu, Su, Xiao. Deficiency of HIF-1 alpha enhances influenza A virus replication by promoting autophagy in alveolar type II epithelial cells. EMERGING MICROBES & INFECTIONS[J]. 2020, 9(1): 691-706, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000522087100001.
[12] Li, Hui, Liu, Liang, Zhang, Dingyu, Xu, Jiuyang, Dai, Huaping, Tang, Nan, Su, Xiao, Cao, Bin. SARS-CoV-2 and viral sepsis: observations and hypotheses. LANCET[J]. 2020, 395(10235): 1517-1520, http://dx.doi.org/10.1016/S0140-6736(20)30920-X.
[13] Li, Ling, Wu, Haiya, Li, Qingmei, Chen, Jie, Xu, Kaifeng, Xu, Jinfu, Su, Xiao. SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection. MOLECULAR IMMUNOLOGY[J]. 2020, 125: 51-62, http://dx.doi.org/10.1016/j.molimm.2020.06.022.
[14] 苏枭. Induction of ASC pyroptosis requires gasdermin or caspase-1/11-dependent mediators and IFN-β from pyroptotic macrophages to Stem Cells. Cell Death & Diseases. 2020, [15] Rujia Tao, Weijun Cao, Manhui Li, Ling Yang, Ruoxuan Dai, Xiaoli Luo, Yang Liu, Baoxue Ge, Xiao Su, Jinfu Xu. PM2.5 compromises antiviral immunity in influenza infection by inhibiting activation of NLRP3 inflammasome and expression of interferon-β. MOLECULAR IMMUNOLOGY. 2020, 125: 178-186, http://dx.doi.org/10.1016/j.molimm.2020.07.001.
[16] Zhang, Cuiping, Zhao, Caiqi, Chen, Xiaoyan, Tao, Rujia, Wang, Sijiao, Meng, Guangxun, Liu, Xing, Shao, Changzhou, Su, Xiao. Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFN beta from pyroptotic macrophages. CELL DEATH & DISEASE[J]. 2020, 11(6): https://www.webofscience.com/wos/woscc/full-record/WOS:000544064600002.
[17] Huang, Y, Zhao, C, Su, X. Neuroimmune regulation of lung infection and inflammation. QJM-AN INTERNATIONAL JOURNAL OF MEDICINEnull. 2019, 112(7): 483-487, https://www.webofscience.com/wos/woscc/full-record/WOS:000482130600002.
[18] 苏枭. Deficiency of HIF-1a in myeloid cells protects Escherichia coli or LPS-induced acute lung injury. QJM. 2018, [19] Caiqi Zhao, Xi Yang, Emily M Su, Yuanyuan Huang, Ling Li, Michael A Matthay, Xiao Su. Signals of vagal circuits engaging with AKT1 in α7 nAChR + CD11b + cells lessen E. coli and LPS-induced acute inflammatory injury. CELL DISCOVERY. 2017, 3: 17009-, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419718/.
[20] Sun, Peiyu, Li, Ling, Zhao, Caiqi, Pan, Mengyao, Qian, Zhikang, Su, Xiao. Deficiency of alpha 7 Nicotinic Acetylcholine Receptor Attenuates Bleomycin-Induced Lung Fibrosis in Mice. MOLECULAR MEDICINE[J]. 2017, 23: 34-49, https://www.webofscience.com/wos/woscc/full-record/WOS:000400983100001.
[21] Shi, Tianyun, He, Yanchao, Sun, Wei, Wu, Yi, Li, Ling, Jie, Zhijun, Su, Xiao. Respiratory Syncytial virus infection compromises asthma tolerance by recruiting interleukin-17A-producing cells via CCR6-CCL20 signaling. MOLECULAR IMMUNOLOGY[J]. 2017, 88: 45-57, http://dx.doi.org/10.1016/j.molimm.2017.05.017.
[22] Yang X, Zhao C, Chen X, Jiang L, Su Xiao. Monocytes primed with GTS-21/α7 nAChR (nicotinic acetylcholine receptor) agonist develop anti-inflammatory memory. QJM: AN INTERNATIONAL JOURNAL OF MEDICINE[J]. 2017, [23] Yang, X, Zhao, C, Chen, X, Jiang, L, Su, Xiao. Monocytes primed with GTS-21/alpha 7 nAChR (nicotinic acetylcholine receptor) agonist develop anti-inflammatory memory. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE[J]. 2017, 110(7): 437-445, https://www.webofscience.com/wos/woscc/full-record/WOS:000405694400007.
[24] He, Yanchao, Sun, Wei, Shi, Jindong, Su, Xiao, Jie, Zhijun. LATE-BREAKING ABSTRACT: The role of IL-17A in the pathogenesis of early infection with RSV increasing susceptibility to asthma. EUROPEAN RESPIRATORY JOURNALnull. 2015, 46: http://dx.doi.org/10.1183/13993003.congress-2015.PA4372.
[25] Gao, Z, Su, X. CFTR regulates acute inflammatory responses in macrophages. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE[J]. 2015, 108(12): 951-958, http://dx.doi.org/10.1093/qjmed/hcv067.
[26] Yang, X, Zhao, C, Gao, Z, Su, X. A novel regulator of lung inflammation and immunity: pulmonary parasympathetic inflammatory reflex. QJM-AN INTERNATIONAL JOURNAL OF MEDICINEnull. 2014, 107(10): 789-792, https://www.webofscience.com/wos/woscc/full-record/WOS:000343699800002.
[27] Wu, Haiya, Yang, Jun, Su, Emily M, Li, Ling, Zhao, Caiqi, Yang, Xi, Gao, Zhaowei, Pan, Mengyao, Sun, Peiyu, Sun, Wei, Jiang, Yiyi, Su, Xiao. Lipoxin A4 and Platelet Activating Factor Are Involved in E. coli or LPS-Induced Lung Inflammation in CFTR-Deficient Mice. PLOS ONE[J]. 2014, 9(3): https://doaj.org/article/556ab1e3e8ed4ea29c757582d2f32b2e.
[28] Wu, Haiya, Li, Ling, Su, Xiao. Vagus Nerve through alpha 7 nAChR Modulates Lung Infection and Inflammation: Models, Cells, and Signals. BIOMED RESEARCH INTERNATIONALnull. 2014, 2014: https://www.webofscience.com/wos/woscc/full-record/WOS:000340125500001.
[29] Zhao, Caiqi, Su, Emily M, Yang, Xi, Gao, Zhaowei, Li, Ling, Wu, Haiya, Jiang, Yiyi, Su, Xiao. Important Role of Platelets in Modulating Endotoxin-Induced Lung Inflammation in CFTR-Deficient Mice. PLOS ONE[J]. 2013, 8(12): https://doaj.org/article/36ec83648caa4c9999e53431bb0edc3f.
[30] Su, Xiao. Leading Neutrophils to the Alveoli Who Is the Guider?. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINEnull. 2012, 186(6): 472-473, https://www.webofscience.com/wos/woscc/full-record/WOS:000308849800003.
[31] Krasnodembskaya, Anna, Samarani, Gianluca, Song, Yuanlin, Zhuo, Hanjing, Su, Xiao, Lee, JaeWoo, Gupta, Naveen, Petrini, Mario, Matthay, Michael A. Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY[J]. 2012, 302(10): L1003-L1013, http://dx.doi.org/10.1152/ajplung.00180.2011.
[32] Bhattacharya, M, Su, G, Su, X, OsesPrieto, J A, Li, J T, Huang, X, Hernandez, H, Atakilit, A, Burlingame, A L, Matthay, M A, Sheppard, D. IQGAP1 is necessary for pulmonary vascular barrier protection in murine acute lung injury and pneumonia. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY[J]. 2012, 303(1): L12-L19, https://www.webofscience.com/wos/woscc/full-record/WOS:000306276000002.
[33] Su, Xiao, Feng, Xiaomei, Terrando, Niccolo, Yan, Yan, Chawla, Ajay, Koch, Lauren G, Britton, Steven L, Matthay, Michael A, Maze, Mervyn. Dysfunction of Inflammation-Resolving Pathways Is Associated with Exaggerated Postoperative Cognitive Decline in a Rat Model of the Metabolic Syndrome. MOLECULAR MEDICINE[J]. 2012, 18(12): 1481-1490, https://www.webofscience.com/wos/woscc/full-record/WOS:000315666800001.
[34] Lee, Joyce S, Su, Xiao, Rackley, Craig, Matthay, Michael A, Gupta, Naveen. Priming With Endotoxin Increases Acute Lung Injury in Mice by Enhancing the Severity of Lung Endothelial Injury. ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY[J]. 2011, 294(1): 165-172, https://www.webofscience.com/wos/woscc/full-record/WOS:000294891200017.
[35] Su, Xiao, Looney, Mark R, Su, Hang Emily, Lee, Jae Woo, Song, Yuanlin, Matthay, Michael A. Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice. INFLAMMATION RESEARCH[J]. 2011, 60(7): 619-632, https://www.webofscience.com/wos/woscc/full-record/WOS:000291695500002.
[36] 苏枭. Requisite Role of the Cholinergic α7 nAChR Pathway in Suppressing Gram-negative Sepsis-induced Acute Lung Inflammatory Injury. JIMMUNOL. 2010, [37] Su, Xiao, Matthay, Michael A. Role of Protease Activated Receptor 2 in Experimental Acute Lung Injury and Lung Fibrosis. ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY[J]. 2009, 292(4): 580-586, https://www.webofscience.com/wos/woscc/full-record/WOS:000264998900014.
[38] Su, Xiao, Looney, Mark R, Gupta, Naveen, Matthay, Michael A. Receptor for advanced glycation end-products (RAGE) is an indicator of direct lung injury in models of experimental lung injury. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY[J]. 2009, 297(1): L1-L5, https://www.webofscience.com/wos/woscc/full-record/WOS:000268276100001.
[39] Michael A Matthay, Mette Johansen, Eric J Brown, Xiao Su, Mark R Looney. CD47 Deficiency Protects Mice from Lipopolysaccharide-Induced Acute Lung Injury and Escherichia coli Pneumonia. AMERICAN ASSOCIATION OF IMMUNOLOGISTS. 2008, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201902027539485ZK.
[40] Hirsch, Jan, Niemann, Claus U, Hansen, Kirk C, Choi, SooJinNa, Su, Xiao, Frank, James A, Fang, Xiaohui, Hirose, Ryutaro, Theodore, Pierre, Sapru, Anil, Burlingame, Alma L, Matthay, Michael A. Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion. CRITICAL CARE MEDICINE[J]. 2008, 36(6): 1846-1854, https://www.webofscience.com/wos/woscc/full-record/WOS:000256513000022.
[41] Xiao Su, Jae Woo Lee, Michael A Matthay, Boris Popov, Naveen Gupta, Vladimir Serikov. Intrapulmonary Delivery of Bone Marrow-Derived Mesenchymal Stem Cells Improves Survival and Attenuates Endotoxin-Induced Acute Lung Injury in Mice. AMERICAN ASSOCIATION OF IMMUNOLOGISTS. 2007, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201902025790215ZK.
[42] 苏枭. Activation of the α7 Nicotinic Acetylcholine Receptor Reduces Acid-induced Acute Lung Injury in Mice and Rats. Am J Respir Cell Mol Biol. 2007, [43] Matthay, Michael A, Su, Xiao. Pulmonary barriers to pneumonia and sepsis. NATURE MEDICINEnull. 2007, 13(7): 780-781, https://www.webofscience.com/wos/woscc/full-record/WOS:000247902800014.
[44] Su, X, Robriquet, L, Folkesson, HG, Matthay, MA. Protective effect of endogenous beta-adrenergic tone on lung fluid balance in acute bacterial pneumonia in mice. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY[J]. 2006, 290(4): L769-L776, https://www.webofscience.com/wos/woscc/full-record/WOS:000236573100017.
[45] 苏枭. Ligation of protease-activated receptor 1 enhances alpha(v) beta(6) integrin-dependent TGF-β activation and promotes acute lung injury. J Clin Invest. 2006, [46] Mark R Looney, Xiao Su, Jessica A Van Ziffle, Clifford A Lowell, Michael A Matthay. Neutrophils and their Fcγ receptors are essential in a mouse model of transfusion-related acute lung injury. JOURNAL OF CLINICAL INVESTIGATION. 2006, 116(6): 1615-1623, [47] 苏枭. PAR2 activation induces acute lung inflammation by neuropeptide dependent mechanisms. J Immunol. 2005, [48] Su, X, Song, YL, Jiang, JJ, Bai, CX. The role of aquaporin-1 (AQP1) expression in a murine model of lipopolysaccharide-induced acute lung injury. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY[J]. 2004, 142(1): 1-11, http://dx.doi.org/10.1016/j.resp.2004.05.001.
[49] Su, X, Looney, M, Robriquet, L, Fang, XH, Matthay, MA. Direct visual instillation as a method for efficient delivery of fluid into the distal airspaces of anesthetized mice. EXPERIMENTAL LUNG RESEARCH[J]. 2004, 30(6): 479-493, https://www.webofscience.com/wos/woscc/full-record/WOS:000223475600005.
[50] Su, X, Wang, L, Song, YL, Bai, CX. Inhibition of inflammatory responses by ambroxol, a mucolytic agent, in a murine model of acute lung injury induced by lipopolysaccharide. INTENSIVE CARE MEDICINE[J]. 2004, 30(1): 133-140, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227363/.
[51] Wang, L, Zhu, DM, Su, X, Bai, CX. Acute cardiopulmonary effects of a dual-endothelin receptor antagonist on oleic acid-induced pulmonary arterial hypertension in dogs. EXPERIMENTAL LUNG RESEARCH[J]. 2004, 30(1): 31-42, https://www.webofscience.com/wos/woscc/full-record/WOS:000188032100003.
[52] Su, X, Bai, CX, Hong, QY, Zhu, DM, He, LX, Wu, JP, Ding, F, Fang, XH, Matthay, MA. Effect of continuous hemofiltration on hemodynamics, lung inflammation and pulmonary edema in a canine model of acute lung injury. INTENSIVE CARE MEDICINE[J]. 2003, 29(11): 2034-2042, https://www.webofscience.com/wos/woscc/full-record/WOS:000186423500028.