085600-材料与化工
085600-材料与化工
070205-凝聚态物理

生物传感、生物成像材料制备及应用
表面等离子共振传感元件及应用研究
OLED光物理特性检测研究

2002-03--2005-03   中国科学院长春光学精密机械与物理研究所   光学博士
1999-09--2002-03   东北师范大学物理系   教育学硕士
1995-09--1999-07   东北师范大学物理系   理学学士

   

2014-07~现在, 中科院理化所, 项目研究员
2009-03~现在, 中国科学院理化技术研究所, 副研究员
2007-05~2009-03,中国科学院理化技术研究所, 助理研究员
2005-03~2007-05,中国科学院物理研究所, 博士后
2002-03~2005-03,中国科学院长春光学精密机械与物理研究所, 光学博士
1999-09~2002-03,东北师范大学物理系, 教育学硕士
1995-09~1999-07,东北师范大学物理系, 理学学士

   

（1） 中国科学院理化技术研究所举办的2010年“优秀青年学术报告会”上荣获优秀奖, 一等奖, 研究所（学校）, 2010

（ 1 ） 一种用于革兰氏阴性菌检测的表面等离子体共振传感芯片及其制备方法、应用, 2017, 第 1 作者, 专利号: 20171191448.6

（ 2 ） 一种用于肿瘤细胞检测的表面等离子体工作传感芯片及其制备方法、应用, 2016, 第 3 作者, 专利号: ZL201310163547.9

（ 3 ） 一种表面等离子体共振传感芯片级其制备、应用, 2015, 第 1 作者, 专利号: 201210453443.7

（ 4 ） 基于激光共聚焦成像的波长调制表面等离子共振检测装置, 2011, 第 1 作者, 专利号: 201110436264.8

（ 5 ） 偏振调制型激光共聚焦表面等离子共振装置, 2011, 第 1 作者, 专利号: 201110436241.7

（ 6 ） 激光共聚焦斜入射椭偏高通量生物分子反应成像检测装置, 2010, 第 1 作者, 专利号: 201010183340.4

   

（1） High sensitivity gram-negative bacteria biosensor based on a small-molecule modified surface plasmon resonance chip studied using a laser scanning confocal imaging-surface plasmon resonance system, Sensors and Actuators B: Chemical, 2017, 通讯作者
（2） A Ratiometric Fluorescent Probe for Lysosomal pH Measurement and Imaging in Living Cells Using Single-Wavelength Excitation, Analytical Chemistry, 2017, 通讯作者
（3） NIR ratiometric luminescence detection of pHfluctuation in living cells with hemicyanine derivative-assembled upconversion nanophosphors, Analytical Chemistry, 2017, 通讯作者
（4） Near-infrared ratiometric fluorescent detection of arginine in lysosome with a new hemicyanine derivative, Biosensors and Bioelectronics, 2017, 通讯作者
（5） A colorimetric and ratiometric fluorescent probe for hydrazine and its application in living cells with low dark toxicity, Sensors and Actuators B: Chemical, 2017, 通讯作者
（6） Surface-enhanced Raman scattering substrate based on cysteamine-modified gold nanoparticle aggregation for highly sensitive pentachlorophenol detection, RSC Adv., 2016, 通讯作者
（7） Investigation of biological cell–small molecule interactions with a gold surface plasmon resonance sensor using a laser scanning confocal imagingsurface plasmon resonance system, RSC Adv., 2016, 通讯作者
（8） A 1,8-naphthalimide-based chemosensor with an off-on fluorescence and lifetime imaging response for intracellular Cr3+ and further for S2-, Dyes and Pigments, 2016, 通讯作者
（9） Online evaluation system for the photo-physical properties of organic photoelectricmaterials and device integrated with the device fabrication instrument, Proc. SPIE, 2016, 第 1 作者
（10） Characterization of mono-specific monoclonal antibodies using oblique-incidence reflectivity difference approach, mAbs, 2015, 通讯作者
（11） Highly selective red-emitting H2S fluorescent probe with a large Stokes shift, Dyes and Pigments, 2015, 通讯作者
（12） Ultrasensitive and selective detection of mercury (II) in serum based on the goldfilm sensor using a laser scanning confocal imaging-surface plasmon resonancesystem in real time, Proc. SPIE., 2015, 通讯作者
（13） A new fluorescent probe for Al3+ based on rhodamine 6G and its application to bioimaging, Dalton Trans, 2014, 通讯作者
（14） Investigation of biological cell-protein interactions using SPR sensor through laser scanning confocal imaging-surface plasmon resonance system, SpectrochimicaActa Part A: Molecular and Biomolecular Spectroscopy, 2014, 通讯作者
（15） A new highly selective fluorescent sensor for detection of Cd2+ and Hg2+ based on two different approaches in aqueous solution, Sensors and Actuators B: Chemical, 2014, 通讯作者
（16） Ultrasensitive and selective gold film-based detection of mercury(II) in tap water using al asers canning confocal imaging-surface plasmon resonance system in real time,  Biosensors and Bioelectronics, 2013, 第 1 作者
（17） A Red Fluorescent Probe for Thiols Based on 3-Hydroxyflavone and Its Application in Living Cell, RSC Adv., 2013, 通讯作者
（18） Real time detection of antibody-antigen interaction using a laser scanning confocal imaging-surface plasmon resonance system, Chinese Physics B, 2012, 第 1 作者
（19） A novel sensitive turn-on fluorescent Zn2+ chemosensor based on an easy-to-prepare C3-symmetric Schiff-base derivative in 100 aqueous solution, Orgonic Letter, 2012, 通讯作者
（20） A laser scanning confocal imaging-surface plasmon resonance system application in real time detection of antibody-antigen interaction,, Proceedings of SPIE 8006, 2011, 第 1 作者
（21） A new surface plasmon resonance system with the function transforming freely from wavelength to angle modulation and the primary application in real time detection of antibody-antigen interaction, Proceedings of SPIE 8199, 2011, 通讯作者
（22） An “off-on” fluorescent chemosensor of selectivity to Cr3+ and its application to MCF-7 cells, Tetrahedron , 2011, 通讯作者
（23） “A switching on fluorescent chemodosimeter of selectivity to Zn2+ and its application to MCF-7 cells, Chemical Communication, 2010, 通讯作者

   

（ 1 ） 多光束干涉高灵敏表面等离子共振检测机理与应用研究, 负责人, 国家任务, 2009-01--2012-12
（ 2 ） 北京市科技新星（A）, 负责人, 地方任务, 2009-12--2012-12
（ 3 ） 激光扫描共聚焦高分辨率各项异性显微成像系统, 负责人, 中国科学院计划, 2010-12--2012-12
（ 4 ） 有机薄膜材料与器件光电性能在线检测系统, 参与, 中国科学院计划, 2009-07--2012-12
（ 5 ） 有机光电材料光物理特性在线评价系统研制, 参与, 国家任务, 2013-01--2016-12
（ 6 ） 用于致病菌代谢产物高选择检测的超高灵敏表面等离子共振传感元件, 负责人, 国家任务, 2014-01--2017-12

（1）基于表面等离子共振技术注射用水中细菌内毒素超高灵敏检测   中国化学会第30届学术年会   2016-07-01
（2）Highly Sensitive Detection of Pentachlorophenol by Using AuNP-modified SERS Substrate with Ratio Method   第二届材料化学亚太国际会议国际会议   2015-08-17
（3）Biocompatible Conjugated Polymer Dots as Fluorescent Probes for Biological Imaging   第二届材料化学亚太国际会议国际会议   2015-08-17
（4）Ultrasensitive and selective detection of mercury (II) in serum based onthe gold film sensor using a laser scanning confocal imaging-surfaceplasmon resonance system in real time   2015年光学仪器与技术国际会议   2015-05-17
（5）haracterization of Antigen-mAb Interactions Using Oblique Incidence Reflectivity (OIRD) Method   National Institutes of Health U.S. Department of Health and Human Services，3rd Annual Protein Capture Reagents Program Meeting   2013-12-12
（6）A new surface plasmon resonance system with the function transforming freely from wavelength to angle modulation and the primary application in real time detection of antibody-antigen interaction   Yang, L. Q., Zhang, H. Y., Wang, X. L.,    2011-11-09
（7）A laser scanning confocal imaging-surface plasmon resonance system application in real time detection of antibody-antigen interaction   Zhang, H. Y., Yang, L. Q., Liu, W. M.,    2011-11-04
（8）Application of the laser scanning confocal microscope in fluorescent film sensor research    Zhang, H., Liu, W., Zhao, W., Dai, Q., Wang, P.,    2010-04-20