主要研究1）人脑运作机理：利用功能磁共振成像等神经影像技术研究人脑网络的形成机制、组织机制和信息处理机制，进而理解其与人类认知过程和心理过程的功能联系；2）脑发展与健康：研究脑结构和功能在毕生发展（老化及相关疾病）中的变化特点及影响因素，研究利用基于生活方式和优秀传统文化的干预方法促进个体心身健康发展，并揭示其心理机制和脑机制。

   

0402Z2-认知神经科学
040202-发展与教育心理学
0402Z1-健康心理学

   

2014-03--今 中国科学院心理研究所 副研究员
2011-07--2014-02 中国科学院心理研究所 助理研究员

2021-01-01-2026-12-31,中国老年学和老年医学学会老年心理分会委员, 委员
2016-12-31-2021-12-30,中国心理学会老年心理学专委会委员, 委员

   

（1） 第10届吴文俊人工智能自然科学奖, 一等奖, 其他, 2020
（2） 教育部高等学校科学研究优秀成果奖（科学技术）, 二等奖, 省级, 2020
（3） 中国神经科学学会GSK明日之星奖, 其他, 2011

   

[1] Li, Rui, Miao, Xiaoyan, Han, Buxin, Li, Juan. Cortical thickness of the left parahippocampal cortex links central hearing and cognitive performance in aging. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2023, http://dx.doi.org/10.1111/nyas.14971.
[2] Wang, Yue, Han, Buxin, Li, Min, Li, Juan, Li, Rui. An efficiently working brain characterizes higher mental flow that elicits pleasure in Chinese calligraphic handwriting. CEREBRAL CORTEX. 2023, http://dx.doi.org/10.1093/cercor/bhad047.
[3] Zhang, Shouzi, Liu, Lixin, Zhang, Li, Ma, Li, Wu, Haiyan, He, Xuelin, Cao, Meng, Li, Rui. Evaluating the treatment outcomes of repetitive transcranial magnetic stimulation in patients with moderate-to-severe Alzheimer's disease. FRONTIERS IN AGING NEUROSCIENCE[J]. 2023, 14: http://dx.doi.org/10.3389/fnagi.2022.1070535.
[4] Zhang, Han, Li, Rui, Wen, Xiaotong, Li, Qing, Wu, Xia. Altered Time-Frequency Feature in Default Mode Network of Autism Based on Improved Hilbert-Huang Transform. IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS[J]. 2021, 25(2): 485-492, http://dx.doi.org/10.1109/JBHI.2020.2993109.
[5] Li, Rui, Zhang, Jing, Wu, Xia, Wen, Xiaotong, Han, Buxin. Brain-wide resting-state connectivity regulation by the hippocampus and medial prefrontal cortex is associated with fluid intelligence. BRAIN STRUCTURE & FUNCTION[J]. 2020, 225(5): 1587-1600, http://dx.doi.org/10.1007/s00429-020-02077-8.
[6] Li, Rui, Zhu, Xinyi, Zheng, Zhiwei, Wang, Pengyun, Li, Juan. Subjective well-being is associated with the functional connectivity network of the dorsal anterior insula. NEUROPSYCHOLOGIA[J]. 2020, 141: http://dx.doi.org/10.1016/j.neuropsychologia.2020.107393.
[7] Li, Rui, Zhang, Shouzi, Yin, Shufei, Ren, Weicong, He, Rongqiao, Li, Juan. The fronto-insular cortex causally mediates the default-mode and central-executive networks to contribute to individual cognitive performance in healthy elderly. HUMAN BRAIN MAPPING[J]. 2018, 39(11): 4302-4311, http://dx.doi.org/10.1002/hbm.24247.
[8] Wu, Xia, Li, Qing, Yu, Xinyu, Chen, Kewei, Fleisher, Adam S, Guo, Xiaojuan, Zhang, Jiacai, Reiman, Eric M, Yao, Li, Li, Rui. A Triple Network Connectivity Study of Large-Scale Brain Systems in Cognitively Normal APOE4 Carriers. FRONTIERS IN AGING NEUROSCIENCE[J]. 2016, 8: http://dx.doi.org/10.3389/fnagi.2016.00231.
[9] Yin, Shufei, Zhu, Xinyi, He, Rongqiao, Li, Rui, Li, Juan. Spontaneous Activity in the Precuneus Predicts Individual Differences in Verbal Fluency in Cognitively Normal Elderly. NEUROPSYCHOLOGY[J]. 2015, 29(6): 961-970, http://dx.doi.org/10.1037/neu0000201.
[10] Li, Rui, Ma, Zhenling, Yu, Jing, He, Yong, Li, Juan. Altered local activity and functional connectivity of the anterior cingulate cortex in elderly individuals with subthreshold depression. PSYCHIATRY RESEARCH-NEUROIMAGING[J]. 2014, 222(1-2): 29-36, http://dx.doi.org/10.1016/j.pscychresns.2014.02.013.
[11] Li, Rui, Zhu, Xinyi, Yin, Shufei, Niu, Yanan, Zheng, Zhiwei, Huang, Xin, Wang, Baoxi, Li, Juan. Multimodal intervention in older adults improves resting-state functional connectivity between the medial prefrontal cortex and medial temporal lobe. FRONTIERS IN AGING NEUROSCIENCE[J]. 2014, 6: http://dx.doi.org/10.3389/fnagi.2014.00039.
[12] Li, Rui, Yu, Jing, Zhang, Shouzi, Bao, Feng, Wang, Pengyun, Huang, Xin, Li, Juan, Li, J reprint author, Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Ctr Aging Psychol, Beijing , Peoples R China. Bayesian Network Analysis Reveals Alterations to Default Mode Network Connectivity in Individuals at Risk for Alzheimer's Disease. PLOS ONE[J]. 2013, 8(12): http://dx.doi.org/10.1371/journal.pone.0082104.
[13] 李锐. Alterations of directional connectivity among resting-state networks in Alzheimer’s disease. American Journal of Neuroradiology. 2013, 

   

（ 1 ） 脑老化异质性的认知神经机制—基于静息功能磁共振成像的研究, 主持, 国家级, 2013-01--2015-12
（ 2 ） 基于脑网络计算研究阿尔茨海默病的外显和内隐记忆机制及其在早期识别中, 主持, 市地级, 2011-11--2013-11
（ 3 ） 认知老化异质性的脑功能网络表达, 主持, 市地级, 2013-01--2014-12
（ 4 ） 老年人脑功能连接个体差异及其认知关联, 主持, 市地级, 2014-12--2016-12
（ 5 ） 基于神经影像和心理行为多模态数据的脑老化个体差异图谱绘制与计算, 主持, 国家级, 2017-01--2020-12
（ 6 ） 我国人群增龄过程中健康状态变化特点与规律的研究, 参与, 国家级, 2018-12--2022-12

已指导学生

陆冠琴  硕士研究生  045400-应用心理  

王悦  硕士研究生  040202-发展与教育心理学  

现指导学生

于旭坤  硕士研究生  045400-应用心理