深海微生物生命过程认知及活性物质发掘利用

   

070703-海洋生物学

深海微生物生命过程认知及活性物质发掘利用

2006-12--2013-12   美国加州大学伯克利分校   博士后
2002-09--2006-07   中国科学院微生物研究所   博士
1999-09--2002-07   山东省农业大学   硕士
1995-09--1999-07   山东省农业大学   学士

   

2014-01~现在, 中国科学院海洋研究所, 研究员

2019-06-01-今,中国微生物遗传学会, 副主任
2017-01-01-2021-12-31,海洋湖沼学会药学分会, 秘书长

   

[1] 张全斌, 王清池, 孙超岷, 王晶, 吴宁, 岳洋, 耿丽华. 一种海洋盐单胞菌胞外多糖在制备免疫增强剂中的应用. CN: CN112458128A, 2021-03-09.
[2] 孙超岷, 马宁. 一种苏氨酸脱水酶及其应用. CN: CN109576252A, 2019-04-05.
[3] 吴仕梅, 孙超岷. 枯草芽孢杆菌Bacillus subtilis CS30及其应用. CN: CN109576174A, 2019-04-05.
[4] 孙超岷, 曹若冰, 刘格. 一种海洋芽孢杆菌及其应用. CN: CN107988105A, 2018-05-04.
[5] 孙超岷, 张林林. 海洋芽孢杆菌及其应用. CN: CN107828687A, 2018-03-23.
[6] 孙超岷, 张德超, 刘瑞, 修鹏远. 海洋芽孢杆菌及其产生脂肽的应用. CN: CN106978372A, 2017-07-25.
[7] 孙超岷, 朱玉莹, 马宁. 产碳酸钙放线菌及其应用. CN: CN106635882A, 2017-05-10.
[8] 金维华, 刘格, 孙超岷, 张全斌. 一种全缘马尾藻多糖的应用. CN: CN105596376A, 2016-05-25.

   

[1] Ruining Cai, Wanying He, Jing Zhang, Rui Liu, Ziyu Yin, Xin Zhang, Chaomin Sun. Blue light promotes zero-valent sulfur production in a deep-sea bacterium. The EMBO Journal[J]. 2023, 42(12): [2] Zhi Gui, Guangchao Liu, Xin Liu, Ruining Cai, Rui Liu, Chaomin Sun. A deep-sea bacterium is capable of degrading polyurethane. MICROBIOLOGY SPECTRUM[J]. 2023, e0007323: [3] Rikuan Zheng, Ruining Cai, Chong Wang, Rui Liu, Chaomin Sun. Characterization of the first cultured representative of "Candidatus Thermofonsia" Clade 2 within Chloroflexi reveals its phototrophic lifestyle. MBIO[J]. 2022, 13(2): https://pubmed.ncbi.nlm.nih.gov/35229635/.
[4] Ronrong Gao, Rui Liu, Chaomin Sun. A marine fungus Alternaria alternata FB1 efficiently degrades polyethylen. Journal of Hazardous Materials[J]. 2022, 431(128617): https://pubmed.ncbi.nlm.nih.gov/35359103/.
[5] Yeqi Shan, Ge Liu, Ruining Cai, Rui Liu, Rikuan Zheng, Chaomin Sun. A Deep-Sea Bacterium Senses Blue Light via a BLUF-Dependent Pathway. MSYSTEMS[J]. 2022, 7(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805636/.
[6] Cai, Ruining, He, Wanying, Liu, Rui, Zhang, Jing, Zhang, Xin, Sun, Chaomin. Deep-Sea In Situ Insights into the Formation of Zero-Valent Sulfur Driven by a Bacterial Thiosulfate Oxidation Pathway. MBIO[J]. 2022, 13(4): http://dx.doi.org/10.1128/mbio.00143-22.
[7] Wang, Yun, Liu, Ge, Liu, Rui, Wei, Maosheng, Zhang, Jinxiang, Sun, Chaomin. EPS364, a Novel Deep-Sea Bacterial Exopolysaccharide, Inhibits Liver Cancer Cell Growth and Adhesion. MARINE DRUGS[J]. 2021, 19(3): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004136/.
[8] Rikuan Zheng, Shimei Wu, Chaomin Sun. Pseudodesulfovibrio Cashew sp. Nov. , a Novel Deep-Sea Sulfate-Reducing Bacterium, Linking Heavy Metal Resistance and Sulfur Cycle. MICROORGANISMS[J]. 2021, 9(429): https://doaj.org/article/419d0aeea5a84fbda59159b89baf10fc.
[9] Ruining Cai, Jing Zhang, Rui Liu, Chaomin Sun. Metagenomic Insights into the Metabolic and Ecological Functions of Abundant Deep-Sea Hydrothermal Vent DPANN Archaea. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2021, 87(9): https://www.webofscience.com/wos/woscc/full-record/WOS:000640616700020.
[10] Zheng, Rikuan, Liu, Rui, Shan, Yeqi, Cai, Ruining, Liu, Ge, Sun, Chaomin. Characterization of the first cultured free-living representative of Candidatus Izemoplasma uncovers its unique biology. ISME JOURNAL[J]. 2021, 15(9): 2676-2691, http://dx.doi.org/10.1038/s41396-021-00961-7.
[11] Zheng, Rikuan, Cai, Ruining, Liu, Rui, Liu, Ge, Sun, Chaomin. Maribellus comscasis sp. nov., a novel deep-sea Bacteroidetes bacterium, possessing a prominent capability of degrading cellulose. ENVIRONMENTAL MICROBIOLOGY[J]. 2021, 23(8): 4561-4575, http://dx.doi.org/10.1111/1462-2920.15650.
[12] Rongrong Gao, Chaomin Sun. A marine bacterial community capable of degrading poly(ethylene terephthalate) and polyethylene. JOURNAL OF HAZARDOUS MATERIALS[J]. 2021, 416: [13] Ma, Ning, Sha, Zhongli, Sun, Chaomin. Formation of cadmium sulfide nanoparticles mediates cadmium resistance and light utilization of the deep-sea bacteriumIdiomarinasp.OT37-5b. ENVIRONMENTAL MICROBIOLOGY[J]. 2021, 23(2): 934-948, https://www.webofscience.com/wos/woscc/full-record/WOS:000566517400001.
[14] Ma, Ning, Sun, Chaomin. Cadmium sulfide nanoparticle biomineralization and biofilm formation mediate cadmium resistance of the deep-sea bacterium Pseudoalteromonas sp. MT33b. ENVIRONMENTAL MICROBIOLOGY REPORTS. 2021, 13(3): 325-336, http://dx.doi.org/10.1111/1758-2229.12933.
[15] Liu, Ge, Shan, Yeqi, Zheng, Rikuan, Liu, Rui, Sun, Chaomin. Growth promotion of a deep-sea bacterium by sensing infrared light through a bacteriophytochrome photoreceptor. ENVIRONMENTAL MICROBIOLOGY[J]. 2021, 23(8): 4466-4477, http://dx.doi.org/10.1111/1462-2920.15639.
[16] Ning Ma, Ruining Cai, Chaomin Sun. Threonine dehydratase enhances bacterial cadmium resistance via driving cysteine desulfuration and biomineralization of cadmium sulfide nanocrystals. JOURNAL OF HAZARDOUS MATERIALS[J]. 2021, 417: [17] Liu, Ge, Liu, Rui, Shan, Yeqi, Sun, Chaomin. Marine bacterial exopolysaccharide EPS11 inhibits migration and invasion of liver cancer cells by directly targeting collagen I. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2021, 297(4): [18] Wu, Zuodong, Zheng, Rikuan, Liu, Ge, Liu, Rui, Wu, Shimei, Sun, Chaomin. Calcium protects bacteria against cadmium stress via reducing nitric oxide production and increasing iron acquisition. ENVIRONMENTAL MICROBIOLOGY[J]. 2021, 23(7): 3541-3553, http://dx.doi.org/10.1111/1462-2920.15237.
[19] Zheng, Rikuan, Wu, Shimei, Sun, Chaomin. MerF is a novel regulator of deep-seaPseudomonas stutzeriflagellum biogenesis and motility. ENVIRONMENTAL MICROBIOLOGY[J]. 2021, 23(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000579739900001.
[20] Liu, Rui, Zheng, Rikuan, Liu, Ge, Sun, Chaomin. The cyclic lipopeptides suppress the motility ofVibrio alginolyticusvia targeting the Na+-driven flagellar motor componentMotX. ENVIRONMENTAL MICROBIOLOGY[J]. 2020, 22(10): 4424-4437, https://www.webofscience.com/wos/woscc/full-record/WOS:000552750800001.
[21] Zheng, Rikuan, Sun, Chaomin. Sphingosinithalassobacter tenebrarum sp. nov., isolated from a deep-sea cold seep. INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY[J]. 2020, 70(10): 5561-5566, http://dx.doi.org/10.1099/ijsem.0.004448.
[22] Jing Zhang, Rui Liu, Shichuan Xi, Ruining Cai, Xin Zhang, Chaomin Sun. A novel bacterial thiosulfate oxidation pathway provides a new clue about the formation of zero-valent sulfur in deep sea. THE ISME JOURNAL[J]. 2020, 14(9): 2261-2274, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608252/.
[23] Zhang, Jing, Liu, Rui, Xi, Shichuan, Cai, Ruining, Zhang, Xin, Sun, Chaomin. A novel bacterial thiosulfate oxidation pathway provides a new clue about the formation of zero-valent sulfur in deep sea. ISME JOURNAL[J]. 2020, 14(9): 2261-2274, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608252/.
[24] Wang, Qingchi, Liu, Weixiang, Yue, Yang, Sun, Chaomin, Zhang, Quanbin. Proteoglycan from Bacillus sp. BS11 Inhibits the Inflammatory Response by Suppressing the MAPK and NF-kappa B Pathways in Lipopolysaccharide-Induced RAW264.7 Macrophages. MARINE DRUGS[J]. 2020, 18(12): http://dx.doi.org/10.3390/md18120585.
[25] Zhou, Shengnan, Liu, Ge, Zheng, Rikuan, Sun, Chaomin, Wu, Shimei. Structural and Functional Insights into Iturin W, a Novel Lipopeptide Produced by the Deep-Sea Bacterium Bacillus sp. Strain wsm-1. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2020, 86(21): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580537/.
[26] 马士德, 张林林, 段继周, 王在东, 刘瑞, 马岩, 韩文, 孙超岷. 青岛中港微型生物膜中污损细菌群落初探. 广西科学院学报[J]. 2019, 35(2): 155-160, http://lib.cqvip.com/Qikan/Article/Detail?id=7002235013.
[27] 马士德, 张林林, 修鹏远, 韩文, 刘瑞, 王启冉, 孙超岷, 段继周. 青岛港湾防污涂料/海水界面细菌污损群落变化初探. 中国涂料[J]. 2019, 52-57, http://lib.cqvip.com/Qikan/Article/Detail?id=90718485504849574849484857.
[28] Shimei Wu, Ge Liu, Shengnan Zhou, Zhenxia Sha, Chaomin Sun. Characterization of Antifungal Lipopeptide Biosurfactants Produced by Marine Bacterium Bacillus sp. CS30. MARINE DRUGS[J]. 2019, 17(4): https://doaj.org/article/3dcc4225a8074b8f97506f6e7c7fdf6b.
[29] Wang, Ju, Liu, Ge, Ma, Weiping, Lu, Zhongxia, Sun, Chaomin. Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth and Metastasis via Blocking Cell Adhesion and Attenuating Filiform Structure Formation. MARINE DRUGS[J]. 2019, 17(1): https://doaj.org/article/6a52f96a7b794cc5ad048f8fa8e0fe11.
[30] 孙超岷. Sorafenib kills Huh7.5 liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via ATP-AMPK-mTOR-SREBP1 signaling pathway. FASEB Journal. 2019, [31] Liu, Ge, Wang, Kai, Kuang, Shan, Cao, Ruobing, Bao, Li, Liu, Rui, Liu, Hongwei, Sun, Chaomin. The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death. CELL DEATH & DISEASE[J]. 2018, 9(6): https://doaj.org/article/8b58295baab34818bbc9a9b171b15d55.
[32] Liu, Ge, Wang, Kai, Kuang, Shan, Cao, Ruobing, Bao, Li, Liu, Rui, Liu, Hongwei, Sun, Chaomin. The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death. CELL DEATH & DISEASE[J]. 2018, 9(6): https://doaj.org/article/8b58295baab34818bbc9a9b171b15d55.
[33] Zhang, Linlin, Sun, Chaomin. Fengycins, Cyclic Lipopeptides from Marine Bacillus subtilis Strains, Kill the Plant-Pathogenic Fungus Magnaporthe grisea by Inducing Reactive Oxygen Species Production and Chromatin Condensation. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2018, 84(18): http://dx.doi.org/10.1128/AEM.00445-18.
[34] Zheng, Rikuan, Wu, Shimei, Ma, Ning, Sun, Chaomin. Genetic and Physiological Adaptations of Marine Bacterium Pseudomonas stutzeri 273 to Mercury Stress. FRONTIERS IN MICROBIOLOGY[J]. 2018, 9: https://doaj.org/article/fbd3419d9eb246c786b149d0695cb7e6.
[35] Cao, Ruobing, Jin, Weihua, Shan, Yeqi, Wang, Ju, Liu, Ge, Kuang, Shan, Sun, Chaomin. Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis. MARINE DRUGS[J]. 2018, 16(3): https://doaj.org/article/afc9178779504d52b7f9ef6083bb8128.
[36] 孙超岷. Cyclic lipopeptides fengycins from marine bacterium Bacillus subtilis kill plant pathogenic fungus Magnaporthe grisea by inducing reactive oxygen species production and chromatin condensation. Applied and Environmental Microbiology. 2018, [37] Zhang, Linlin, Tian, Xueying, Kuang, Shan, Liu, Ge, Zhang, Chengsheng, Sun, Chaomin. Antagonistic Activity and Mode of Action of Phenazine-1-Carboxylic Acid, Produced by Marine Bacterium Pseudomonas aeruginosa PA31x, Against Vibrio anguillarum In vitro and in a Zebrafish In vivo Model. FRONTIERS IN MICROBIOLOGY[J]. 2017, 8: http://ir.qdio.ac.cn/handle/337002/136379.
[38] Wu, Shimei, Zheng, Rikuan, Sha, Zhenxia, Sun, Chaomin. Genome Sequence of Pseudomonas stutzeri 273 and Identification of the Exopolysaccharide EPS273 Biosynthesis Locus. MARINE DRUGS[J]. 2017, 15(7): http://ir.qdio.ac.cn/handle/337002/143086.
[39] Jin Weihua, Zhang Wenjing, Liu Ge, Yao Jianting, Shan Tifeng, Sun Chaomin, Zhang Quanbin. The structure-activity relationship between polysaccharides from Sargassum thunbergii and anti-tumor activity. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2017, [40] Zhu, Yuying, Huang, Pei, Yang, Na, Liu, Rui, Liu, Xueting, Dai, Huanqin, Zhang, Lixin, Song, Fuhang, Sun, Chaomin. Establishment and Application of a High Throughput Screening System Targeting the Interaction between HCV Internal Ribosome Entry Site and Human Eukaryotic Translation Initiation Factor 3. FRONTIERS IN MICROBIOLOGY[J]. 2017, 8: https://doaj.org/article/3204edfd179a4be6a8c4a0495e90ab89.
[41] Xiu, Pengyuan, Liu, Rui, Zhang, Dechao, Sun, Chaomin. Pumilacidin-Like Lipopeptides Derived from Marine Bacterium Bacillus sp Strain 176 Suppress the Motility of Vibrio alginolyticus. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2017, 83(12): http://dx.doi.org/10.1128/AEM.00450-17.
[42] Kuang, Shan, Liu, Ge, Cao, Ruobing, Zhang, Linlin, Yu, Qiang, Sun, Chaomin. Mansouramycin C kills cancer cells through reactive oxygen species production mediated by opening of mitochondrial permeability transition pore. ONCOTARGET[J]. 2017, 8(61): 104057-104071, http://ir.qdio.ac.cn/handle/337002/154342.
[43] Zhu, Yuying, Ma, Ning, Jin, Weihua, Wu, Shimei, Sun, Chaomin. Genomic and Transcriptomic Insights into Calcium Carbonate Biomineralization by Marine Actinobacterium Brevibacterium linens BS258. FRONTIERS IN MICROBIOLOGY[J]. 2017, 8: http://ir.qdio.ac.cn/handle/337002/136740.
[44] 孙超岷. Mansouramycin C induces reactive oxygen species and tumor cell apoptosis through opening of the mitochondrial permeability transition pore. Oncotarget. 2017, [45] 孙超岷. Pumilacidin-like lipopeptides derived from marine bacterium Bacillus sp. suppress the motility of Vibrio alginolyticus.. Applied and Environmental Microbiology. 2017, [46] Yang, Na, Sun, Chaomin, Zhang, Lixin, Liu, Jianguo, Song, Fuhang. Identification and Analysis of Novel Inhibitors against NS3 Helicase and NS5B RNA-Dependent RNA Polymerase from Hepatitis C Virus 1b (Con1). FRONTIERS IN MICROBIOLOGY[J]. 2017, 8: http://ir.qdio.ac.cn/handle/337002/143059.
[47] 马士德, 修鹏远, 马岩, 严清冉, 郭为民, 李丽娜, 李文军, 任海涛, 符策鹄, 王启冉, 李博亮, 孙超岷, 段继周. 三亚海洋环境试验站海洋细菌污损群落初探. 中国涂料[J]. 2017, 32(12): 54-58, http://lib.cqvip.com/Qikan/Article/Detail?id=674612608.
[48] Jin, Weihua, Liu, Ge, Zhong, Weihong, Sun, Chaomin, Zhang, Quanbin. Polysaccharides from Sargassum thunbergii: Monthly variations and anti-complement and anti-tumour activities. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2017, 105: 1526-1531, http://ir.qdio.ac.cn/handle/337002/143064.
[49] Liu, Ge, Wu, Shimei, Jin, Weihua, Sun, Chaomin. Amy63, a novel type of marine bacterial multifunctional enzyme possessing amylase, agarase and carrageenase activities. SCIENTIFIC REPORTS[J]. 2016, 6: http://dx.doi.org/10.1038/srep18726.
[50] Wu, Shimei, Liu, Ge, Jin, Weihua, Xiu, Pengyuan, Sun, Chaomin. Antibiofilm and Anti-Infection of a Marine Bacterial Exopolysaccharide Against Pseudomonas aeruginosa. FRONTIERS IN MICROBIOLOGY[J]. 2016, 7: http://ir.qibebt.ac.cn/handle/337004/7964.
[51] Yang, Na, Sun, Chaomin. The Inhibition and Resistance Mechanisms of Actinonin, Isolated from Marine Streptomyces sp NHF165, against Vibrio anguillarum. FRONTIERS IN MICROBIOLOGY[J]. 2016, 7: https://doaj.org/article/a4a68e3575ca43da84b1fa2012de4451.
[52] Liu, Ge, Kuang, Shan, Wu, Shimei, Jin, Weihua, Sun, Chaomin. A novel polysaccharide from Sargassum integerrimum induces apoptosis in A549 cells and prevents angiogensis in vitro and in vivo. SCIENTIFIC REPORTS[J]. 2016, 6: http://ir.qibebt.ac.cn/handle/337004/8278.
[53] Yang, Na, Sun, Chaomin. Pelagibacterium lixinzhangensis sp nov., a Novel Member of the Genus Pelagibacterium. CURRENT MICROBIOLOGY[J]. 2016, 72(5): 551-556, http://dx.doi.org/10.1007/s00284-016-0989-9.
[54] Wu, Shimei, Liu, Ge, Zhang, Dechao, Li, Chaoxu, Sun, Chaomin. Purification and biochemical characterization of an alkaline protease from marine bacteria Pseudoalteromonas sp 129-1. JOURNAL OF BASIC MICROBIOLOGY[J]. 2015, 55(12): 1427-1434, http://ir.qibebt.ac.cn/handle/337004/6816.
[55] Yang, Na, Zhang, Lixin, Sun, Chaomin. Algoriella xinjiangensis gen. nov., sp nov., a new psychrotolerant bacterium of the family Flavobacteriaceae. ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY[J]. 2015, 108(5): 1107-1116, http://dx.doi.org/10.1007/s10482-015-0564-6.
[56] 孙超岷. Architecture of human translation initiation factor.. Structure. 2013, [57] Sun, Chaomin, QuerolAudi, Jordi, Mortimer, Stefanie A, AriasPalomo, Ernesto, Doudna, Jennifer A, Nogales, Eva, Cate, Jamie H D. Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation. NUCLEIC ACIDS RESEARCH[J]. 2013, 41(15): 7512-7521, http://dx.doi.org/10.1093/nar/gkt510.
[58] 孙超岷. Functional reconstitution of human translation initiation factor eIF3.. 2011, [59] 孙超岷. C virus core-derived peptides inhibit genotype 1b viral genome replication via interaction with DDX3X.. PLOS One. 2010, [60] 孙超岷. Construction and application of a novel shuttle expression vector based on haloarchaeal plasmid pSCM201.. 2009, [61] 孙超岷. The Helix-Loop-Helix Motif at the N-terminal of HalI Is Essential for Its Immunity Function against Halocin C8.. 2008, [62] Zhou, Ligang, Zhou, Meixian, Sun, Chaomin, Han, Jing, Lu, Qiuhe, Zhou, Jian, Xiang, Hua. Precise determination, cross-recognition, and functional analysis of the double-strand origins of the rolling-circle replication plasmids in haloarchaea. JOURNAL OF BACTERIOLOGY[J]. 2008, 190(16): 5710-5719, http://www.corc.org.cn/handle/1471x/2389582.
[63] Zhou, Ligang, Zhou, Meixian, Sun, Chaomin, Xiang, Hua, Tan, Huarong. Genetic analysis of a novel plasmid pZMX101 from Halorubrum saccharovorum: determination of the minimal replicon and comparison with the related haloarchaeal plasmid pSCM201. FEMS MICROBIOLOGY LETTERS[J]. 2007, 270(1): 104-108, http://www.corc.org.cn/handle/1471x/2380196.
[64] 孙超岷. Unidirectional theta replication of pSCM201, a novel structurally stable plasmid from extremely halophilic archaea. J Bacteriol. 2006, [65] Pei, HD, Liu, JF, Cheng, Y, Sun, CM, Wang, C, Lu, YP, Ding, J, Zhou, J, Xiang, H. Expression of SARS-coronavirus nucleocapsid protein in Escherichia coli and Lactococcus lactis for serodiagnosis and mucosal vaccination. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2005, 68(2): 220-227, http://www.corc.org.cn/handle/1471x/2377734.
[66] Sun, CM, Li, Y, Mei, SS, Lu, QH, Zhou, LG, Xiang, H. A single gene directs both production and immunity of halocin C8 in a haloarchaeal strain AS7092. MOLECULAR MICROBIOLOGY[J]. 2005, 57(2): 537-549, http://124.16.144.217/handle/311023/1680.
[67] Zhou, MX, Xiang, H, Sun, CM, Li, Y, Liu, JF, Tan, HR. Complete sequence and molecular characterization of pNB101, a rolling-circle replicating plasmid from the haloalkaliphilic archaeon Natronobacterium sp strain AS7091. EXTREMOPHILES[J]. 2004, 8(2): 91-98, https://www.webofscience.com/wos/woscc/full-record/WOS:000220683300001.
[68] 孙超岷. Construction of a novel shuttle vector based on an RCR-plasmid from a haloalkaliphilic archaeon and transformation into other haloarchaea.. 2003, [69] 孙超岷. on the fertilizer efficiency of tobacco fungicide T. virid and its colonization on tobacco leaf and root.. 2002, 

   

（ 1 ） 海洋微生物活性物质的发掘和利用, 主持, 部委级, 2014-01--2016-12
（ 2 ） 抑制丙肝病毒复制的海洋微生物活性物质的筛选及分子机理研究, 主持, 国家级, 2015-01--2018-12
（ 3 ） 海洋微生物生命过程及活性物质发掘利用, 主持, 部委级, 2015-07--2018-12
（ 4 ） 重要海洋微生物活性物质的合成调控、生理 功能及作用机理研究, 主持, 国家级, 2015-01--2018-12
（ 5 ） 海洋微生物活性物质的发掘和利用, 主持, 省级, 2016-06--2019-06
（ 6 ） 海洋微生物在重金属去除中的作用机制及应用, 主持, 省级, 2017-01--2021-12
（ 7 ） 新型深海微生物酶/胞外多糖应用潜力评价与应用示范, 主持, 研究所（学校）, 2018-01--2020-12
（ 8 ） 海洋微生物活性物质的发掘利用, 主持, 研究所（学校）, 2018-01--2020-12
（ 9 ） 深海冷泉微生物代谢产物资源挖掘与药用潜力评估, 主持, 国家级, 2018-07--2021-12
（ 10 ） 板块俯冲体系下特殊生命过程, 主持, 部委级, 2018-09--2023-08

（1）海洋微生物在环境修复领域中的资源发掘及应用   中国微生物学会第八届地质微生物学学术研讨会   2019-06-14
（2）海洋微生物生命活动认知及活性物质发掘利用   第八届全国微生物遗传学研讨会   2018-07-29
（3）Biosynthesis and action mechanism insights of marine polysaccharide with antibiofilm or anticancer activity   第十一届世界糖基转移酶学术会议   2018-06-21
（4）The screening and mechanism studies of anti-hepatoma cocktail   第十三届海洋药物学术年会暨2017 国际海洋药物研讨会   2017-11-07
（5）海洋微生物活性物质的发掘和利用：从浅海到深海   鳌山论坛——“深海生态系统：极端环境与生命过程”   2017-08-31
（6）Genomic and transcriptomic insights into the calcium carbonate biomineralization by marine actinobacterium Brevibacterium lines BS258   2017-04-27
（7）海洋微生物活性物质的发掘和利用   中国海洋湖沼学会年会   2016-11-08
（8）海洋微生物多糖EPS273的生物合成及其抑制铜绿假单胞菌生物膜形成的作用机制研究   中国微生物遗传学年会   2016-08-05
（9）真核生物翻译起始因子eIF3调控丙肝病毒复制的分子机制   全球华人遗传学大会   2014-10-31
（10）海洋生物农药在植物保护中的应用   青岛农业大学植保大讲堂   2014-10-17
（11）Screening and molecular mechanism studies of marine microbial natural products inhibiting replication of Hepatitis C Virus    全球海洋生物多样性国际会议   2014-10-08
（12）Control the hepatitis c virus by eIF3   Chaomin Sun, Jamie Cate   2012-09-06

已指导学生

朱玉莹  博士研究生  070703-海洋生物学  

修鹏远  硕士研究生  070703-海洋生物学  

曹若冰  硕士研究生  070703-海洋生物学  

刘格  博士研究生  070703-海洋生物学  

张林林  博士研究生  070703-海洋生物学  

郑日宽  硕士研究生  085238-生物工程  

王菊  硕士研究生  070703-海洋生物学  

现指导学生

马宁  博士研究生  070703-海洋生物学  

张晶  博士研究生  070703-海洋生物学  

蔡瑞宁  硕士研究生  070703-海洋生物学  

王芸  硕士研究生  085238-生物工程  

郑日宽  博士研究生  070703-海洋生物学  

高蓉蓉  博士研究生  070703-海洋生物学  

谭颖琪  硕士研究生  070703-海洋生物学  

单业奇  博士研究生  070703-海洋生物学