070320-计算机化学
071023-计算生物学

计算生物学
计算化学

2004-08--2009-10 美国哥伦比亚大学 博士
1999-09--2004-06 中国科学技术大学 学士

   

2014-11--今 上海科技大学 教授
2010-05--2014-11 美国加州大学旧金山分校 博士后
2009-10--2010-04 美国哥伦比亚大学 博士后

   

[1] Ritesh Kumar, Suwen Zhao, Matthew W Vetting, B McKay Wood, Ayano Sakai, Kyuil Cho, Jos Solbiati, Steven C Almo, Jonathan V Sweedler, Matthew P Jacobson, John A Gerlt, John E Cronan. Prediction and Biochemical Demonstration of a Catabolic Pathway for the Osmoprotectant Proline Betaine. MBIO[J]. 2014, 5(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000332526500029.

[2] Jacobson, Matthew P, Kalyanaraman, Chakrapani, Zhao, Suwen, Tian, Boxue. Leveraging structure for enzyme function prediction: methods, opportunities, and challenges. TRENDS IN BIOCHEMICAL SCIENCESnull. 2014, 39(8): 363-371, http://dx.doi.org/10.1016/j.tibs.2014.05.006.

[3] Zhao, Suwen, Sakai, Ayano, Zhang, Xinshuai, Vetting, Matthew W, Kumar, Ritesh, Hillerich, Brandan, San Francisco, Brian, Solbiati, Jose, Steeves, Adam, Brown, Shoshana, Akiva, Eyal, Barber, Alan, Seidel, Ronald D, Babbitt, Patricia C, Almo, Steven C, Gerlt, John A, Jacobson, Matthew P. Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks. ELIFE[J]. 2014, 3: https://doaj.org/article/987f7767be6744a18463d2a7fd3a79e8.

[4] Suwen Zhao, Ritesh Kumar, Ayano Sakai, Matthew W Vetting, B McKay Wood, Shoshana Brown, Jeffery B Bonanno, Brandan S Hillerich, Ronald D Seidel, Patricia C Babbitt, Steven C Almo, Jonathan V Sweedler, John A Gerlt, John E Cronan, Matthew P Jacobson. Discovery of new enzymes and metabolic pathways using structure and genome context. Nature. 2013, 502(7473): 698-702, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966649/.

[5] Suwen Zhao. Exploring enzyme substrate specificity with docking and QM/MM methods: A benchmarking study on the stereo-specificity of D-glucarate dehydratase. Biochemistry. 2013, 
[6] Miller, Edward B, Murrett, Colleen S, Zhu, Kai, Zhao, Suwen, Goldfeld, Dahlia A, Bylund, Joseph H, Friesner, Richard A. Prediction of Long Loops with Embedded Secondary Structure Using the Protein Local Optimization Program. JOURNAL OF CHEMICAL THEORY AND COMPUTATION[J]. 2013, 9(3): 1846-1864, http://dx.doi.org/10.1021/ct301083q.

[7] Zhao, Suwen, Zhu, Kai, Li, Jianing, Friesner, Richard A. Progress in super long loop prediction. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS[J]. 2011, 79(10): 2920-2935, https://www.webofscience.com/wos/woscc/full-record/WOS:000295428900011.

[8] Li, Jianing, Abel, Robert, Zhu, Kai, Cao, Yixiang, Zhao, Suwen, Friesner, Richard A. The VSGB 2.0 model: A next generation energy model for high resolution protein structure modeling. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS[J]. 2011, 79(10): 2794-2812, https://www.webofscience.com/wos/woscc/full-record/WOS:000295428900003.

[9] Suwen Zhao. Towards better refinement of comparative models: Predicting loops in inexact environments. Proteins: Structure, Function, and Bioinformatics. 2008, 
[10] Li, Xin, Jacobson, Matthew P, Zhu, Kai, Zhao, Suwen, Friesner, Richard A. Assignment of polar states for protein amino acid residues using an interaction cluster decomposition algorithm and its application to high resolution protein structure modeling. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS[J]. 2007, 66(4): 824-837, https://www.webofscience.com/wos/woscc/full-record/WOS:000244296100007.

[11] Zhu, Kai, Pincus, David L, Zhao, Suwen, Friesner, Richard A. Long loop prediction using the protein local optimization program. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS[J]. 2006, 65(2): 438-452, https://www.webofscience.com/wos/woscc/full-record/WOS:000240748700016.

[12] Zhao, SW, Liu, L, Fu, Y, Guo, QX. Assessment of the metabolic stability of the methyl groups in heterocyclic compounds using C-H bond dissociation energies: effects of diverse aromatic groups on the stability of methyl radicals. JOURNAL OF PHYSICAL ORGANIC CHEMISTRY[J]. 2005, 18(4): 353-367, https://www.webofscience.com/wos/woscc/full-record/WOS:000227926800009.

[13] Feng, Y, Liu, L, Zhao, SW, Wang, JT, Guo, QX. Origin of conformational restriction in complexes of formyl compounds with boron lewis acids and their related systems. JOURNAL OF PHYSICAL CHEMISTRY A[J]. 2004, 108(42): 9196-9204, https://www.webofscience.com/wos/woscc/full-record/WOS:000224538900027.

[14] Feng, Y, Zhao, SW, Liu, L, Wang, JT, Li, XS, Guo, QX. Blue-shifted dihydrogen bonds. JOURNAL OF PHYSICAL ORGANIC CHEMISTRY[J]. 2004, 17(12): 1099-1106, https://www.webofscience.com/wos/woscc/full-record/WOS:000225144400004.

[15] Feng, Y, Liu, L, Wang, JT, Zhao, SW, Guo, QX. Homolytic C-H and N-H bond dissociation energies of strained organic compounds. JOURNAL OF ORGANIC CHEMISTRY[J]. 2004, 69(9): 3129-3138, https://www.webofscience.com/wos/woscc/full-record/WOS:000221268200027.

   

（1） GPCR配体预测和机理研究，主持，研究所（学校）级，2014-11--2019-11

（1） Leveraging Structure For Protein Function Prediction，第二届上海GPCR论坛，2014-12，Suwen Zhao