077601-环境科学
071009-细胞生物学
100702-药剂学

环境毒理学
干细胞毒理学
环境污染物的健康效应评估

2007-04--2010-03   日本大阪大学   药学博士学位
2005-04--2007-03   日本大阪大学   药学硕士学位
2000-09--2004-06   兰州大学   生物技术学士学位
2000-09--2004-06   兰州大学   计算机科学与技术双学士学位

   

2014-12~现在, 中国科学院生态环境研究中心, 副研究员
2014-07~2014-11,中国科学院生态环境研究中心, 助理研究员
2012-09~2014-07,北京协和医学院, 博士后
2010-05~2012-07,浙江大学, 博士后

干细胞毒理学

   

[1] Pang, Shaochen, Gao, Yue, Wang, Yanwu, Yao, Xinglei, Cao, Mengxi, Liang, Yong, Song, Maoyong, Jiang, Guibin. Tetrabromobisphenol A perturbs cell fate decisions via BMP signaling in the early embryonic development of zebrafish. JOURNAL OF HAZARDOUS MATERIALS[J]. 2022, 430: http://dx.doi.org/10.1016/j.jhazmat.2022.128512.
[2] Wang, Yuanyuan, Wang, Fengbang, Chen, Zihan, Song, Maoyong, Yao, Xinglei, Jiang, Guibin. In situ High-Throughput Single-Cell Analysis Reveals the Crosstalk between Nanoparticle-Induced Cell Responses. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2021, 55(8): 5136-5142, http://dx.doi.org/10.1021/acs.est.0c08424.
[3] Wenjuan Zhang, Aijing Li, Yu Pan, Fengbang Wang, Ming Li, Yong Liang, Xinglei Yao, Jinghai Song, Maoyong Song, Guibin Jiang. Tetrabromobisphenol A induces THR β-mediated inflammation and uterine injury in mice at environmentally relevant exposure concentrations. Journal of Hazardous Materials. 2021, 407: http://dx.doi.org/10.1016/j.jhazmat.2020.124859.
[4] Zhang, Wenjuan, Li, Aijing, Pan, Yu, Wang, Fengbang, Li, Ming, Liang, Yong, Yao, Xinglei, Song, Jinghai, Song, Maoyong, Jiang, Guibin. Tetrabromobisphenol A induces THR beta-mediated inflammation and uterine injury in mice at environmentally relevant exposure concentrations. JOURNAL OF HAZARDOUS MATERIALS[J]. 2021, 407: http://dx.doi.org/10.1016/j.jhazmat.2020.124859.
[5] Lu, Zhenhua, Meng, Lingbing, Sun, Zhen, Shi, Xiaolei, Shao, Weiwei, Zheng, Yangyang, Yao, Xinglei, Song, Jinghai. Differentially Expressed Genes and Enriched Signaling Pathways in the Adipose Tissue of Obese People. FRONTIERS IN GENETICS[J]. 2021, 12: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175074/.
[6] Pang, Shaochen, Gao, Yue, Li, Aijing, Yao, Xinglei, Qu, Guangbo, Hu, Ligang, Liang, Yong, Song, Maoyong, Jiang, Guibin. Tetrabromobisphenol A Perturbs Erythropoiesis and Impairs Blood Circulation in Zebrafish Embryos. ENVIRONMENTAL SCIENCE & TECHNOLOGY[J]. 2020, 54(20): 12998-13007, https://www.webofscience.com/wos/woscc/full-record/WOS:000584422500021.
[7] Wang, Yuanyuan, Hu, Ligang, Xia, Tian, Yao, Xinglei, Yin, Yongguang, Wang, Fengbang, Song, Maoyong, Jiang, Guibin. High-Throughput Single Cell Analysis Reveals the Heterogeneity of QDots-Induced Response in Macrophages. ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS[J]. 2020, 7(5): 337-342, https://www.webofscience.com/wos/woscc/full-record/WOS:000535244900010.
[8] Yao, Xinglei, Cao, Dong, Wang, Fengbang, Zhang, Wenjuan, Ma, Chunyan, Song, Maoyong. An overview of omics approaches to characterize the effect of perfluoroalkyl substances in environmental health. TRAC-TRENDS IN ANALYTICAL CHEMISTRYnull. 2019, 121: http://dx.doi.org/10.1016/j.trac.2018.12.021.
[9] Wang, Fengbang, Wang, Yuanyuan, Qu, Guangbo, Yao, Xinglei, Ma, Chunyan, Song, Maoyong, Wang, Hailin, Jiang, Guibin. Ultralong AgNWs-induced toxicity in A549 cells and the important roles of It ROS and autophagy. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY[J]. 2019, 186: [10] Ma, Chunyan, Yang, Chenggong, Wang, Bin, Chen, Cheng, Wang, Fengbang, Yao, Xinglei, Song, Maoyong. Effects of H2O on HCHO and CO oxidation at room-temperature catalyzed by MCo2O4 (M = Mn, Ce and Cu) materials. APPLIED CATALYSIS B-ENVIRONMENTAL[J]. 2019, 254: 76-85, http://dx.doi.org/10.1016/j.apcatb.2019.04.085.
[11] Li, Xueyan, Li, Aijing, Zhang, Wenjuan, Liu, Xiaowei, Liang, Yong, Yao, Xinglei, Song, Maoyong. A pilot study of mothers and infants reveals fetal sex differences in the placental transfer efficiency of heavy metals. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY[J]. 2019, 186: [12] Wang, Fengbang, Wang, Yuanyuan, Yao, Xinglei, Ma, Chunyan, Yin, Yongguang, Song, Maoyong. Length and diameter-dependent phagocytosis and cytotoxicity of long silver nanowires in macrophages. CHEMOSPHERE[J]. 2019, 237: http://dx.doi.org/10.1016/j.chemosphere.2019.124565.
[13] Fengbang Wang, Yuanyuan Wang, Guangbo Qu, Xinglei Yao, Chunyan Ma, Maoyong Song, Hailin Wang, Guibin Jiang. Ultralong AgNWs-induced toxicity in A549 cells and the important roles of ROS and autophagy. Ecotoxicology and Environmental Safety. 2019, 186: http://dx.doi.org/10.1016/j.ecoenv.2019.109742.
[14] Dong, Hengzhi, Yao, Xinglei, Liu, Shuyu, Yin, Nuoya, Faiola, Francesco. Non-cytotoxic nanomolar concentrations of bisphenol A induce human mesenchymal stem cell adipogenesis and osteogenesis. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY[J]. 2018, 164: 448-454, http://ir.rcees.ac.cn/handle/311016/41000.
[15] Li, Hongling, Zhu, Li, Chen, Huimin, Li, Tangping, Han, Qin, Wang, Shihua, Yao, Xinglei, Feng, Hongli, Fan, Linyuan, Gao, Shaorong, Boyd, Richard, Cao, Xu, Zhu, Ping, Li, Jing, Keating, Armand, Su, Xiaodong, Zhao, Robert Chunhua. Generation of Functional Hepatocytes from Human Adipose-Derived MYC+ KLF4(+) GMNN(+) Stem Cells Analyzed by Single-Cell RNA-Seq Profiling. STEM CELLS TRANSLATIONAL MEDICINE[J]. 2018, 7(11): 792-805, https://www.webofscience.com/wos/woscc/full-record/WOS:000449756700006.
[16] Wan L, Yao X, Faiola F, Liu B, Zhang T, Tabata Y, Mizuguchi H, Nakagawa S, Gao JQ, Zhao RC. Coating with spermine-pullulan polymer enhances adenoviral transduction of mesenchymal stem cells. INTERNATIONAL JOURNAL OF NANOMEDICINE[J]. 2016, 11: 6763-6769, https://doaj.org/article/0a70645c3ae4409cac1c88baec1f3fd8.
[17] Xinglei Yao, Nuoya Yin, Francesco Faiola. Stem cell toxicology:a powerful tool to assess pollution effects on human health. 国家科学评论：英文版[J]. 2016, 430-450, http://lib.cqvip.com/Qikan/Article/Detail?id=78658382504849544852484952.
[18] Yao, Xinglei, Yin, Nuoya, Faiola, Francesco. Stem cell toxicology: a powerful tool to assess pollution effects on human health. NATIONAL SCIENCE REVIEW[J]. 2016, 3(4): 430-450, http://lib.cqvip.com/Qikan/Article/Detail?id=78658382504849544852484952.
[19] Yin, Nuoya, Yao, Xinglei, Zhou, Qunfang, Faiola, Francesco, Jiang, Guibin. Vitamin E attenuates silver nanoparticle-induced effects on body weight and neurotoxicity in rats. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2015, 458(2): 405-410, http://ir.rcees.ac.cn/handle/311016/32696.
[20] 姚醒蕾, 殷诺雅, Francesco Faiola. 基于干细胞毒理学研究双酚A污染物的健康效应. 中国毒理学会第七次全国毒理学大会暨第八届湖北科技论坛null. 2015, http://ir.rcees.ac.cn/handle/311016/33400.
[21] Yin Nuoya, Yao Xinglei, Qin Zhanfen, Wang YuanLiang, Faiola Francesco. Assessment of Bisphenol A (BPA) neurotoxicity in vitro with mouse embryonic stem cells. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA[J]. 2015, 36(1): 181-187, http://dx.doi.org/10.1016/j.jes.2015.06.004.
[22] Faiola, Francesco, Yin, Nuoya, Yao, Xinglei, Jiang, Guibin. The Rise of Stem Cell Toxicology. ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2015, 49(10): 5847-5848, http://ir.rcees.ac.cn/handle/311016/32686.
[23] Yao, Xinglei, Zhou, Na, Wan, Li, Su, Xiaodong, Sun, Zhao, Mizuguchi, Hiroyuki, Yoshioka, Yasuo, Nakagawa, Shinsaku, Zhao, Robert Chunhua, Gao, JianQing. Polyethyleneimine-coating enhances adenoviral transduction of mesenchymal stem cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2014, 447(3): 383-387, https://www.webofscience.com/wos/woscc/full-record/WOS:000336413900001.
[24] Yao, XingLei, Yoshioka, Yasuo, Ruan, GuiXin, Chen, YuZhe, Mizuguchi, Hiroyuki, Mukai, Yohei, Okada, Naoki, Gao, JianQing, Nakagawa, Shinsaku. Optimization and Internalization Mechanisms of PEGylated Adenovirus Vector with Targeting Peptide for Cancer Gene Therapy. BIOMACROMOLECULES[J]. 2012, 13(8): 2402-2409, https://www.webofscience.com/wos/woscc/full-record/WOS:000307422300022.
[25] Yao, Xinglei, Yoshioka, Yasuo, Morishige, Tomohiro, Eto, Yusuke, Narimatsu, Shogo, Kawai, Yasuaki, Mizuguchi, Hiroyuki, Gao, JianQing, Mukai, Yohei, Okada, Naoki, Nakagawa, Shinsaku. Tumor Vascular Targeted Delivery of Polymer-conjugated Adenovirus Vector for Cancer Gene Therapy. MOLECULAR THERAPY[J]. 2011, 19(9): 1619-1625, http://dx.doi.org/10.1038/mt.2011.112.

   

（ 1 ） 新型持久性环境污染物对间充质干细胞自我更新和分化能力的影响机制, 主持, 国家级, 2016-01--2019-12
（ 2 ） 典型污染物的环境暴露与健康危害机制 项目三, 参与, 部委级, 2014-07--2019-06