基本信息
严冬 男 博导 中国科学院分子植物科学卓越创新中心(植物生理生态研究所)
电子邮件: yandong@sibs.ac.cn
通信地址: 上海市枫林路300号
邮政编码:
电子邮件: yandong@sibs.ac.cn
通信地址: 上海市枫林路300号
邮政编码:
招生信息
招生专业
071010-生物化学与分子生物学
招生方向
昆虫发育信号途径
教育背景
2002-09--2009-06 美国辛辛那提大学 博士1996-09--2000-07 南京大学 学士
工作经历
工作简历
2016-08~现在, 上海植物生理生态研究所, 研究员2010-06~2016-07,美国哈佛大学医学院, 博士后
出版信息
发表论文
(1) Xio is a novel component of the Drosophila sex determination pathway and RNA N6-methyladenosine methyltransferase complex, PNAS, 2018, 通讯作者(2) The m6A pathway facilitates sex determination in Drosophila, Nature Communications, 2017, 其他(合作组作者)(3) Spenito is required for sex determination in Drosophila melanogaster, PNAS, 2015, 第 1 作者(4) Histone H1-Mediated Epigenetic Regulation Controls Germline Stem Cell Self-Renewal by Modulating the Acetylation of H4 Lysine 16, Nature Communications, 2015, 其他(合作组作者)(5) The Transgenic RNAi Project at Harvard Medical School: Resources and Validation, Genetics, 2015, 其他(合作组作者)(6) Genome-Wide RNAi Screen Identifies Networks Involved in Intestinal Stem Cell Regulation in Drosophila, Cell Reports, 2015, 第 6 作者(7) A sharp end to sugary Wingless travels, The Journal of Cell Biology, 2014, 第 2 作者(8) A regulatory network of Drosophila germline stem cell self-renewal, Developmental Cell, 2014, 第 1 作者(9) Depleting gene activities in early Drosophila embryos with the “maternal-Gal4-shRNA” system, Genetics, 2013, 第 2 作者(10) Proteomic and functional genomic landscape of receptor tyrosine kinase and Ras/ERK signaling, Science Signaling, 2011, 第 4 作者(11) The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development, Development, 2010, 第 1 作者(12) The core protein of glypican Dally-like determines its biphasic activity in Wingless morphogen signaling, Developmental Cell, 2009, 第 1 作者(13) Opposing roles for glypicans in Hedgehog signalling, Nature Cell Biology, 2008, 第 1 作者(14) Drosophila glypican Dally-like acts in FGF-receiving cells to modulate FGF signaling during tracheal morphogenesis, Developmental Biology, 2007, 第 1 作者(15) Drosophila Glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc, Development, 2005, 第 2 作者(16) Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis and is controlled by glypican members of heparan sulfate proteoglycans, Cell, 2004, 第 3 作者(17) Mutation of a lysine residue in a homeodomain generates dominant negative thyroid transcription factor 1, Biochemistry, 2004, 第 2 作者(18) Peroxisome proliferator-activated receptor gamma and ligands inhibit surfactant protein B gene expression in the lung, The Journal of Biological Chemistry, 2003, 第 2 作者(19) An enhancer region determines hSP-B gene expression in bronchiolar and ATII epithelial cells in transgenic mice, American Journal of Physiology Lung Cellular and Molecular Physiology, 2003, 第 4 作者
发表著作
(1) Generating and Interpretation of Morphogen Gradients (Shaping morphogen gradient by proteoglycans.), Cold Spring Harbor Laboratory Press, 2010-03, 第 1 作者