070703-海洋生物学
086000-生物与医药

生态毒理学
逆境适应机制
海洋牧场

2007-09--2010-06   中国科学院海洋研究所   博士
2004-09--2007-06   中国科学院海洋研究所   硕士
2000-09--2004-06   中国海洋大学   学士

   

2020-10~现在, 中国科学院烟台海岸带研究所, 研究员
2014-03~2020-10,中国科学院烟台海岸带研究所, 副研究员
2010-06~2014-03,中国科学院烟台海岸带研究所, 助理研究员
2007-09~2010-06,中国科学院海洋研究所, 博士
2004-09~2007-06,中国科学院海洋研究所, 硕士
2000-09~2004-06,中国海洋大学, 学士

生态毒理学概论与研究进展

   

（1） 渤海典型污染物生态毒理效应与分子生物标志物研究, 二等奖, 市地级, 2018
（2） 海洋生态环境大数据集成及智慧平台的应用示范, 二等奖, 市地级, 2018
（3） 现代海洋牧场构建技术创新与集成应用, , 院级, 2017

（ 1 ） 紫贻贝G型溶菌酶基因及其重组蛋白和应用, 2014, 第 1 作者, 专利号: ZL201110421428.X

   

（1） Microplastic uptake in commercial fishes from the Bohai Sea, China., Chemosphere, 2021, 第 1 作者
（2） Microplastic Pollution in Nearshore Sediment from the Bohai Sea Coastline, Bulletin of Environmental Contamination and Toxicology, 2021, 通讯作者
（3） Toxic effects of exposure to microplastics with environmentally relevant shapes and concentrations: Accumulation, energy metabolism and tissue damage in oyster Crassostrea gigas., Environmental Pollution, 2021, 通讯作者
（4） Spatial and seasonal variation of biofilm formation on microplastics in coastal waters, Science of The Total Environment, 2021, 通讯作者
（5） Oxidative stress biomarkers, physiological responses and proteomic profiling in oyster (Crassostrea gigas) exposed to microplastics with irregular-shaped PE and PET microplastic, Science of The Total Environment, 2021, 通讯作者
（6） Microplastics in soils: a review of possible sources, analytical methods and ecological impacts, Journal of Chemical Technology & Biotechnology, 2020, 通讯作者
（7） A systems analysis of microplastic pollution in Laizhou Bay, China., Science of The Total Environment, 2020, 通讯作者
（8） Research Progress of Microplastics in Freshwater Sediments in China., Environmental Science and Pollution Research, 2020, 通讯作者
（9） Microplastic ingestion by the farmed sea cucumber Aposticopus japonicus in China, Environmental Pollution, 2019, 第 2 作者
（10） Microplastic in cultured oysters from different coastal areas of China, Science of The Total Environment, 2019, 第 2 作者
（11） The influence of three antibiotics on the growth, intestinal enzyme activities, and immune response of the juvenile sea cucumber Apostichopus japonicus selenka, Fish & Shellfish Immunology, 2019, 通讯作者
（12） Microplastic pollution in the surface sediments collected from Sishili Bay, North Yellow Sea, China, Marine Pollution Bulletin, 2019, 通讯作者
（13） The effects of benzo[a]pyrene on the composition of gut microbiota and the gut health of the juvenile sea cucumber Apostichopus japonicus Selenka, Fish & Shellfish Immunology, 2019, 通讯作者
（14） Two macrophage migration inhibitory factors (MIFs) from the clam Ruditapes philippinarum: Molecular characterization, localization and enzymatic activities., Fish & Shellfish immunology, 2018, 通讯作者
（15） Microplastic pollution in sediments from the Bohai Sea and the Yellow Sea, China., Science of The Total Environment, 2018, 通讯作者
（16） CO2-induced ocean acidification impairs the immune function of the Pacific oyster against Vibrio splendidus challenge: An integrated study from a cellular and proteomic perspective, Science of The Total Environment, 2018, 第 2 作者
（17） Seawater acidification aggravated cadmium toxicity in the oyster Crassostrea gigas: Metal bioaccumulation, subcellular distribution and multiple physiological responses., Science of The Total Environment, 2018, 第 3 作者
（18） A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum: Investigation of the antibacterial activities and mode of action., Fish & shellfish immunology, 2018, 第 3 作者
（19） Digital gene expression analysis in the gills of Ruditapes philippinarum exposed to short-and long-term exposures of ammonia nitrogen., Aquatic Toxicology, 2018, 第 5 作者
（20） Molecular characterization, expression and antimicrobial activities of two c-type lysozymes from manila clam Venerupis philippinarum., Developmental & Comparative Immunology, 2017, 第 2 作者
（21） Molecular characterization, expression and functional analysis of two Kazal-type serine protease inhibitors from Venerupis philippinarum., Fish & shellfish immunology, 2017, 第 3 作者
（22） Individual and combined toxicities of benzo[a]pyrene and 2,2′,4,4′-Tetrabromodiphenyl Ether on early life stages of the Pacific oyster, Crassostrea gigas., Bulletin of Environmental Contamination and Toxicology, 2017, 通讯作者
（23） Combined toxicity of cadmium and lead on early life stages of the Pacific oyster, Crassostrea gigas., Invertebrate Survival Journal, 2017, 通讯作者
（24） Molecular characterization and antibacterial activity of a phage-type lysozyme from the Manila clam, Ruditapes philippinarum., Fish & shellfish immunology, 2017, 第 2 作者
（25） Understanding regulation of microRNAs on intestine regeneration in the sea cucumber Apostichopus japonicus using high-throughput sequencing., Comparative Biochemistry and Physiology Part D, 2017, 第 6 作者
（26） Effects of ocean acidification on immune responses of the Pacific oyster Crassostrea gigas, Fish & Shellfish immunology, 2016, 第 1 作者
（27） Impact of metal pollution on shrimp Crangon affinis by NMR-based metabolomics, Marine Pollution Bulletin, 2016, 第 3 作者
（28） An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas., Marine Pollution Bulletin, 2016, 第 3 作者
（29） An integrated proteomic and metabolomics study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA), Chemosphere, 2016, 第 3 作者
（30） Molecular diversity and evolution of defensins in the Manila clam Ruditapes philippinarum, Fish & Shellfish immunology, 2015, 第 1 作者
（31） Proteomic and metabolomic responses of Pacific oyster Crassostrea gigas to elevated pCO2 exposure, Journal of Proteomics, 2015, 第 2 作者
（32） A metabolomic investigation of the effects of metal pollution in oysters Crassostrea hongkongensis, Marine Pollution Bulletin, 2015, 第 2 作者
（33） Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO2, Comparative Biochemistry and Physiology, Part D, 2015, 第 2 作者
（34） A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action, Developmental and Comparative Immunology, 2015, 第 3 作者
（35） Molecular characterization of two glutathione peroxidase genes in Mytilus alloprovincialis and their transcriptional responses to sub-chronic arsenate and cadmium exposure, Invertebrate Survival Journal, 2014, 第 1 作者
（36） Identification and mRNA expression of two17-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis following exposure to endocrine disrupting chemicals, Environmental Toxicology and Pharmacology, 2014, 第 2 作者
（37） A novel C-type lysozyme from Mytilus galloprovincialis: Insight into innate immunity and molecular evolution of invertebrate C-type lysozymes, PLoS one, 2013, 第 1 作者
（38） Molecular characterization of a manganese superoxide dismutase and copper/zinc superoxide dismutase from the mussel Mytilus galloprovincialis, Fish & Shellfish immunology, 2013, 第 1 作者
（39） Molecular cloning, characterization and expression profiles of thioredoxin 1 and thioredoxin 2 genes in Mytilus galloprovincialis, Chinese Journal of Oceanology and Limnology, 2013, 第 1 作者
（40） A metabolomics investigation on arsenic-induced toxicological effects in the clam Ruditapes philippinarum under different salinities, EcotoxicologyandEnvironmentalSafety, 2013, 第 3 作者
（41） Identification of glutaredoxin 1 and glutaredoxin 2 genes from Venerupis philippinarum and their responses to benzo[a]pyrene and bacterial challenge, Fish & Shellfish Immunology, 2012, 通讯作者
（42） Toxic effects of benzo[a]pyrene (Bap) and Aroclor1254 on embryogenesis, larval growth, survival and metamorphosis of the bivalve Meretrix meretrix, Ecotoxicology, 2012, 第 1 作者
（43） Two goose-type lysozymes in Mytilus galloprovincialis: possible function diversification and adaptive evolution, PLoS One, 2012, 第 1 作者
（44） Responses of thioredoxin 1 and thioredoxin-related protein 14 mRNAs to cadmium and copper stresses in Venerupis philippinarum, Comparative Biochemistry and Physiology, Part C, 2011, 第 1 作者
（45） Involvement of phosphatidylinositol signaling pathway during serotonin-induced oocyte maturation of Mercenaria mercenaria, Chinese journal of oceanology and limnology, 2011, 第 1 作者
（46） Analysis of metallotionein expression and antioxidant enzymes activities in clam Meretrix meretrix larvae under sublethal cadmium exposure, Aquatic toxicology, 2010, 第 1 作者
（47） Toxicity of lead, cadmium and mercury on embryogenesis, survival, growth and metamorphosis of Meretrix meretrix larvae, Ecotoxicology, 2009, 第 1 作者
（48） Involvment of Ca2+ signaling pathway during oocyte maturation of the northern quahog Mercenaria mercenaria, Journal of Shellfish Research, 2009, 第 2 作者
（49） cAMP信号通路在5-羟色胺诱导硬壳蛤卵母细胞成熟过程中的作用, 高技术通讯, 2008, 第 1 作者

   

（ 1 ） 莱州湾塑料微粒（microplastics）的污染现状及其毒性效应研究, 负责人, 国家任务, 2016-01--2019-12
（ 2 ） 微塑料对海洋生物的毒性效应, 负责人, 中国科学院计划, 2016-01--2019-12
（ 3 ） 烟台牟平海洋牧场生态安全和环境保障, 参与, 中国科学院计划, 2015-01--2018-12
（ 4 ） 陆基海洋生态系统模拟装备的研制, 负责人, 中国科学院计划, 2018-01--2019-12
（ 5 ） 海岸带生态农牧场关键技术集成与示范, 负责人, 中国科学院计划, 2018-01--2019-06
（ 6 ） 中集渔业本底调查项目, 负责人, 境内委托项目, 2018-01--2018-12
（ 7 ） 高效海洋生态牧场关键技术集成与示范, 负责人, 中国科学院计划, 2017-01--2018-06