基本信息
吴倩 女 中国科学院生物物理研究所
电子邮件: qianwu@ibp.ac.cn
通信地址: 北京市朝阳区大屯路15号
邮政编码:
电子邮件: qianwu@ibp.ac.cn
通信地址: 北京市朝阳区大屯路15号
邮政编码:
招生信息
招生专业
071008-发育生物学
招生方向
大脑皮层发育
教育背景
2003-08--2008-04 University of Pittsburgh 博士学位
工作经历
工作简历
2011-10~现在, 中国科学院生物物理研究所, 副研究员2008-05~2011-09,University of Pittsburgh, 博士后2003-08~2008-04,University of Pittsburgh, 博士学位
教授课程
发育神经生物学
专利与奖励
专利成果
( 1 ) 皮层扩张以及沟回形成的小鼠模型的建立, 2017, 第 2 作者, 专利号: 201710610807.0( 2 ) 一种类脑器官器的制备方法和应用, 2017, 第 2 作者, 专利号: 201710512944.0( 3 ) 建立可应用于人类疾病研究的雪貂模型的方法及其应用, 2015, 第 3 作者, 专利号: 201510587647.3
出版信息
发表论文
(1) A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex, Nature, 2018, 第 4 作者(2) Vertical Transmission of the Zika Virus Causes Neurological Disorders in Mouse Offspring, Sci Rep, 2018, 第 3 作者(3) Morphological and Physiological Characteristics of Ebf2-EGFP-Expressing Cajal-Retzius Cells in Developing Mouse Neocortex, Cerebral Cortex, 2018, 通讯作者(4) Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis, Cell Research, 2018, 第 5 作者(5) The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding, Cell Stem Cell, 2017, 第 4 作者(6) Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like(ASPM related primary) microcephaly disease, Protein Cell, 2017, 通讯作者(7) LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain, Nature Communications, 2016, 第 2 作者(8) CRISPR/Cas9-mediated genome engineering of the ferret, Cell Research, 2015, 第 2 作者(9) Induced pluripotency and direct reprogramming: a new window for treatment of neurodegenerative diseases, Protein Cell, 2013, 通讯作者(10) Neuronal stem cells in the central nervous system and in human diseases, Protein Cell, 2012, 第 1 作者(11) Partial Mesenchymal to Epithelial Reverting Transition in Breast and Prostate Cancer Metastases, Cancer Microenvironment, 2012, 第 2 作者(12) Altered CXCR3 Isoform Expression Regulates Prostate Cancer Cell Migration and Invasion, Molecular Cancer, 2012, 第 1 作者(13) Hepatocyte induced re-expression of E-cadherin in breast and prostate cancer cells increases chemoresistance, Clinical & Experimental Metastasis, 2012, 第 2 作者(14) Deficiency in myosin light-chain phosphorylation causes cytokinesis failure and multipolarity in cancer cells, Oncogene, 2010, 第 1 作者(15) The c-Myc target Glycoprotein1balpha links cytokinesis failure to oncogenic signal transduction pathways in cultured human cells, PLoS One, 2010, 第 1 作者(16) Intercellular transfer of proteins as identified by stable isotope labeling of amino acids in cell culture, J Biol Chem, 2010, 第 4 作者
科研活动
科研项目
( 1 ) 教育部留学回国人员科研启动基金, 负责人, 国家任务, 2013-01--2015-12( 2 ) 中心体蛋白CDK5RAP2在大脑皮层发育中的作用和分子机理, 负责人, 国家任务, 2015-01--2017-12( 3 ) 成体神经干细胞的命运决定机制与功能研究, 参与, 国家任务, 2014-01--2018-08( 4 ) Rcor2在小鼠大脑皮层发育中调控中间神经元发生的分子机制, 负责人, 国家任务, 2017-01--2020-12( 5 ) 特定谱系示踪hPSC的构建及分化体系的优化与机制解析, 参与, 国家任务, 2017-07--2021-10