神经发育的分子细胞基础

神经发育障碍性疾病的病变机制

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071006-神经生物学
071010-生物化学与分子生物学

神经发育的分子基础
神经退行性疾病致病机制

2009-09--2012-06   暨南大学   博士学位
2005-09--2008-12   北京协和医学院   硕士学位
2001-09--2005-07   兰州大学   学士学位

博士

博士

   

2017-03~现在, 中国科学院深圳先进技术研究院, 副研究员
2014-12~2017-02,香港科技大学深圳研究院, 研究与项目开发经理
2012-07~2014-11,暨南大学, 博士后
2009-01~2009-08,北京协和医学院, 研究助理

   

[1] 陈宇, 陈艺菁, 樊颖颖, 陈岳文, 许进英. 一种阿尔兹海默症生物标志物天冬酰胺及其应用. CN202111074848.5, 2022-09-14.
[2] 陈宇, 陈艺菁, 樊颖颖, 陈岳文, 许进英. 一种阿尔兹海默症生物标志物及其筛选方法和应用. CN202111042127.6, 2022-09-07.
[3] 陈宇, 屈雪琪, 林力, 陈岳文. 一种神经退行性疾病标志物Prnp及其应用. CN114645086A, 2022-06-21.
[4] 陈宇, 陈艺菁, 陈岳文, 许进英, 樊颖颖. 检测阿尔兹海默症肠道菌群标志物的表达丰度的方法和装置. CN114622022A, 2022-06-14.
[5] 陈宇, 屈雪琪, 林力, 陈岳文, 许进英. 一种提取神经突触体的方法. CN114621921A, 2022-06-14.
[6] 陈宇, 陈艺菁, 李寅虎, 樊颖颖, 陈岳文, 陈静, 柴岳. 一种基于粪便的阿尔兹海默症生物标志物及其应用. CN202210448068.0, 2022-04-26.
[7] 陈宇, 陈艺菁, 李寅虎, 樊颖颖, 陈岳文, 柴岳, 陈静. 一种阿尔兹海默症生物标志物及其应用. CN202210448532.6, 2022-04-26.
[8] 陈宇, 许进英, 陈岳文, 柴岳, 陈静. 一种蛋白棒状体标志物及其应用. CN202210443960.X, 2022-04-25.
[9] 陈宇, 叶涛, 陈艺菁, 樊颖颖, 陈岳文, 许进英. 一种阿尔兹海默症生物标志物S-甲基-5'-硫代腺苷及其应用. CN202111091735.6, 2021-09-17.
[10] 陈宇, 陈艺菁, 樊颖颖, 陈岳文, 叶涛, 许进英. 一种阿尔兹海默症生物标志物肌苷及其应用. CN202111059965.4, 2021-09-10.
[11] 陈宇, 陈艺菁, 樊颖颖, 陈岳文, 叶涛, 许进英. 一种阿尔兹海默症生物标志物L-缬氨酸及其应用. CN202111059934.9, 2021-09-10.
[12] 陈宇, 陈岳文, 许进英, 陈艺菁. 一种神经退行性疾病标志物Chromogranin B及其应用. CN: CN112858684A, 2021-05-28.
[13] 陈宇, 陈岳文, 许进英, 陈艺菁. 一种神经退行性疾病标志物β-spectrin及其应用. CN: CN112858685A, 2021-05-28.
[14] 李伟丽, 陈宇, 陈岳文. 一种可调式双孔插芯针夹持器. CN: CN211560186U, 2020-09-25.

   

[1] Yuewen Chen, Zhenyan Xu, Jing Chen, Yue Qiu, Lin Yuan, Jing Duan, Li Chen, Yu Chen. Coronin 2B Regulates Neuronal Migration via Rac1-Dependent Multipolar-Bipolar Transition. JOURNAL OF NEUROSCIENCE[J]. 2023, 43(2): 211-220, https://www.jneurosci.org/content/43/2/211.long.
[2] Li, Yinhu, Chen, Yijing, Fan, Yingying, Chen, Yuewen, Chen, Yu. Dynamic network modeling of gut microbiota during Alzheimer's disease progression in mice. GUT MICROBES[J]. 2023, 15(1): http://dx.doi.org/10.1080/19490976.2023.2172672.
[3] Xiaopu Zhou, Yu Chen, Fanny C F Ip, Yuanbing Jiang, Han Cao, Ge Lv, Huan Zhong, Jiahang Chen, Tao Ye, Yuewen Chen, Yulin Zhang, Shuangshuang Ma, Ronnie M N Lo, Estella P S Tong, Alzheimers Disease Neuroimaging Initiative, Vincent C T Mok, Timothy C Y Kwok, Qihao Guo, Kin Y Mok, Maryam Shoai, John Hardy, Lei Chen, Amy K Y Fu, Nancy Y Ip. Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction. COMMUNICATIONS MEDICINE[J]. 2023, 3(1): 1-20, https://doaj.org/article/1179b0a6657942b580123646d3f1699e.
[4] Guan, Mingfeng, Chai, Yue, Yi, Ran, Chen, Yuewen, Ip, Jacque P K, Ye, Tao, Chen, Yu. Generation of a homozygous ABCA7-knockout human iPSC line using the CRISPR/Cas9 system. STEM CELL RESEARCH[J]. 2023, 66: http://dx.doi.org/10.1016/j.scr.2022.103000.
[5] Yang Du, Rui Qiu, Lei Chen, Yuewen Chen, Zhifeng Zhong, Peng Li, Fangcheng Fan, Yong Cheng. Identification of serum exosomal metabolomic and proteomic profiles for remote ischemic preconditioning. JOURNAL OF TRANSLATIONAL MEDICINE[J]. 2023, 21(1): 1-11, http://dx.doi.org/10.1186/s12967-023-04070-1.
[6] Cao, Han, Zhou, Xiaopu, Chen, Yu, Ip, Fanny C F, Chen, Yuewen, Lai, Nicole C H, Lo, Ronnie M N, Tong, Estella P S, Mok, Vincent C T, Kwok, Timothy C Y, Fu, Amy K Y, Ip, Nancy Y, Alzheimers Dis Neuroimaging Initi. Association of SPI1 Haplotypes with Altered SPI1 Gene Expression and Alzheimer's Disease Risk. JOURNAL OF ALZHEIMERS DISEASE[J]. 2022, 86(4): 1861-1873, http://dx.doi.org/10.3233/JAD-215311.
[7] Qu, Xueqi, Lin, Li, Yi, Wanying, Sun, Changyu, Chen, Yuewen, Chen, Yu. Early Changes in Transcriptomic Profiles in Synaptodendrosomes Reveal Aberrant Synaptic Functions in Alzheimer's Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2022, 23(16): http://dx.doi.org/10.3390/ijms23168888.
[8] Duan, Yangyang, Ye, Tao, Qu, Zhe, Chen, Yuewen, Miranda, Abigail, Zhou, Xiaopu, Lok, KaChun, Chen, Yu, Fu, Amy K Y, Gradinaru, Viviana, Ip, Nancy Y. Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer's disease alleviates amyloid-related pathologies in mice. NATURE BIOMEDICAL ENGINEERING[J]. 2022, 6(2): 168-180, http://dx.doi.org/10.1038/s41551-021-00759-0.
[9] Tao Ye, Yangyang Duan, Hayley W S Tsang, He Xu, Yuewen Chen, Han Cao, Yu Chen, Amy K Y Fu, Nancy Y Ip. Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases. COMMUNICATIONS BIOLOGY[J]. 2021, 4(1): https://doaj.org/article/70fb7c21e42e47428a1ea40e2a8b140e.
[10] Lin Yuan, Wanying Yi, Changyu Sun, Shuangshuang Ma, Jiali Wang, Saijuan Liu, Yijing Chen, Yuewen Chen, Yu Chen. EphB2 activates CREB-dependent expression of Annexin A1 to regulate dendritic spine morphogenesis. Biochemical and Biophysical Research Communications[J]. 2021, 584: 107-115, [11] Chen, Yuewen, Xu, Jinying, Zhang, Yulin, Ma, Shuangshuang, Yi, Wanying, Liu, Saijuan, Yu, Xiaojun, Wang, Jiali, Chen, Yu. Coronin 2B regulates dendrite outgrowth by modulating actin dynamics. FEBS LETTERS[J]. 2020, 594(18): 2975-2987, http://dx.doi.org/10.1002/1873-3468.13886.
[12] Ouyang, Li, Chen, Yu, Wang, Ye, Chen, Yuewen, Fu, Amy K Y, Fu, WingYu, Ip, Nancy Y. p39-associated Cdk5 activity regulates dendritic morphogenesis. SCIENTIFIC REPORTS[J]. 2020, 10(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603351/.
[13] Chen, Yijing, Fang, Lihua, Chen, Shuo, Zhou, Haokui, Fan, Yingying, Lin, Li, Li, Jing, Xu, Jinying, Chen, Yuewen, Ma, Yingfei, Chen, Yu. Gut Microbiome Alterations Precede Cerebral Amyloidosis and Microglial Pathology in a Mouse Model of Alzheimer's Disease. BIOMED RESEARCH INTERNATIONAL[J]. 2020, 2020: https://doaj.org/article/fb16f83bda19424aae44eb69492030ed.
[14] Xiaopu Zhou, Yu Chen, Fanny C F Ip, Nicole C H Lai, Yolanda Y T Li, Yuanbing Jiang, Huan Zhong, Yuewen Chen, Yulin Zhang, Shuangshuang Ma, Ronnie M N Lo, Kit Cheung, Estella P S Tong, Ho Ko, Maryam Shoai, Kin Y Mok, John Hardy, Vincent C T Mok, Timothy C Y Kwok, Amy K Y Fu, Nancy Y Ip. Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population. ALZHEIMER'S & DEMENTIA : DIAGNOSIS, ASSESSMENT & DISEASE MONITORING. 2020, 12(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403835/.
[15] Xu, Zhenyan, Chen, Yuewen, Chen, Yu. Spatiotemporal Regulation of Rho GTPases in Neuronal Migration. CELLS[J]. 2019, 8(6): https://doaj.org/article/53c7970349284bc3a1f3690f09e4230b.
[16] Chen, Yuewen, Xu, Jinying, Zhou, Xiaopu, Liu, Saijuan, Zhang, Yulin, Ma, Shuangshuang, Fu, Amy K Y, Ip, Nancy Y, Chen, Yu. Changes of Protein Phosphorylation Are Associated with Synaptic Functions during the Early Stage of Alzheimer's Disease. ACS CHEMICAL NEUROSCIENCE[J]. 2019, 10(9): 3986-3996, https://www.webofscience.com/wos/woscc/full-record/WOS:000487179600009.
[17] Zhou, Xiaopu, Chen, Yu, Mok, Kin Y, Kwok, Timothy C Y, Mok, Vincent C T, Guo, Qihao, Ip, Fanny C, Chen, Yuewen, Mullapudi, Nandita, GiustiRodriguez, Paola, Sullivan, Patrick F, Hardy, John, Fu, Amy K Y, Li, Yun, Ip, Nancy Y, Weiner, Michael W, Aisen, Paul, Petersen, Ronald, Jack, Clifford R, Jagust, William, Trojanowski, John Q, Toga, Arthur W, Beckett, Laurel, Green, Robert C, Saykin, Andrew J, Morris, John, Shaw, Leslie M, Khachaturian, Zaven, Sorensen, Greg, Kuller, Lew, Raichle, Marcus, Paul, Steven, Davies, Peter, Fillit, Howard, Hefti, Franz, Holtzman, David, Mesulam, Marek M, Potter, William, Snyder, Peter, Schwartz, Adam, Montine, Tom, Thomas, Ronald G, Donohue, Michael, Walter, Sarah, Gessert, Devon, Sather, Tamie, Jiminez, Gus, Harvey, Danielle, Bernstein, Matthew, Thompson, Paul, Schuff, Norbert, Borowski, Bret, Gunter, Jeff, Senjem, Matt, Vemuri, Prashanthi, Jones, David, Kantarci, Kejal, Ward, Chad, Koeppe, Robert A, Foster, Norm, Reiman, Eric M, Chen, Kewei, Mathis, Chet, Landau, Susan, Cairns, Nigel J, Householder, Erin, TaylorReinwald, Lisa, Lee, Virginia, Korecka, Magdalena, Figurski, Michal, Crawford, Karen, Neu, Scott, Foroud, Tatiana M, Potkin, Steven G, Shen, Li, Faber, Kelley, Kim, Sungeun, Nho, Kwangsik, Thal, Leon, Buckholtz, Neil, Albert, Marylyn, Frank, Richard, Hsiao, John, Kaye, Jeffrey, Quinn, Joseph, Lind, Betty, Carter, Raina, Dolen, Sara, Schneider, Lon S, Pawluczyk, Sonia, Beccera, Mauricio, Teodoro, Liberty, Spann, Bryan M, Brewer, James, Vanderswag, Helen, Fleisher, Adam, Heidebrink, Judith L, Lord, Joanne L, Mason, Sara S, Albers, Colleen S, Knopman, David, Johnson, Kris, Doody, Rachelle S, VillanuevaMeyer, Javier, Chowdhury, Munir, Rountree, Susan, Dang, Mimi, Stern, Yaakov, Honig, Lawrence S, Bell, Karen L, Ances, Beau, Carroll, Maria, Leon, Sue, Mintun, Mark A, Schneider, Stacy, Oliver, Angela, Marson, Daniel, Griffith, Randall, Clark, David, Geldmacher, David, Brockington, John, Roberson, Erik, Grossman, Hillel, Mitsis, Effie, De ToledoMorrell, Leyla, Shah, Raj C, Duara, Ranjan, Varon, Daniel, Greig, Maria T, Roberts, Peggy, Onyike, Chiadi, DAgostino, Daniel, Kielb, Stephanie, Galvin, James E, Cerbone, Brittany, Michel, Christina A, Rusinek, Henry, de Leon, Mony J, Glodzik, Lidia, De Santi, Susan, Doraiswamy, P Murali, Petrella, Jeffrey R, Wong, Terence Z, Arnold, Steven E, Karlawish, Jason H, Wolk, David, Smith, Charles D, Jicha, Greg, Hardy, Peter, Sinha, Partha, Oates, Elizabeth, Conrad, Gary, Lopez, Oscar L, Oakley, MaryAnn, Simpson, Donna M, Porsteinsson, Anton P, Goldstein, Bonnie S, Martin, Kim, Makino, Kelly M, Ismail, M Saleem, Brand, Connie, Mulnard, Ruth A, Thai, Gaby, McAdamsOrtiz, Catherine, Womack, Kyle, Mathews, Dana, Quiceno, Mary, DiazArrastia, Ramon, King, Richard, Weiner, Myron, MartinCook, Kristen, DeVous, Michael, Levey, Allan I, Lah, James J, Cellar, Janet S, Burns, Jeffrey M, Anderson, Heather S, Swerdlow, Russell H, Apostolova, Liana, Tingus, Kathleen, Woo, Ellen, Silverman, Daniel H S, Lu, Po H, Bartzokis, George, GraffRadford, Neill R, Parfitt, Francine, Kendall, Tracy, Johnson, Heather, Farlow, Martin R, Hake, Ann Marie, Matthews, Brandy R, Herring, Scott, Hunt, Cynthia, Van Dyck, Christopher H, Carson, Richard E, MacAvoy, Martha G, Chertkow, Howard, Bergman, Howard, Hosein, Chris, Hsiung, GingYuek Robin, Feldman, Howard, Mudge, Benita, Assaly, Michele, Bernick, Charles, Munic, Donna, Kertesz, Andrew, Rogers, John, Trost, Dick, Kerwin, Diana, Lipowski, Kristine, Wu, ChuangKuo, Johnson, Nancy, Sadowsky, Carl, Martinez, Walter, Villena, Teresa, Turner, Raymond Scott, Johnson, Kathleen, Reynolds, Brigid, Sperling, Reisa A, Johnson, Keith A, Marshall, Gad, Frey, Meghan, Lane, Barton, Rosen, Allyson, Tinklenberg, Jared, Sabbagh, Marwan N, Belden, Christine M, Jacobson, Sandra A, Sirrel, Sherye A, Kowall, Neil, Killiany, Ronald, Budson, Andrew E, Norbash, Alexander, Johnson, Patricia Lynn, Allard, Joanne, Lerner, Alan, Ogrocki, Paula, Hudson, Leon, Fletcher, Evan, Carmichael, Owen, Olichney, John, DeCarli, Charles, Kittur, Smita, Borrie, Michael, Lee, TY, Bartha, Rob, Johnson, Sterling, Asthana, Sanjay, Carlsson, Cynthia M, Preda, Adrian, Nguyen, Dana, Tariot, Pierre, Reeder, Stephanie, Bates, Vernice, Capote, Horacio, Rainka, Michelle, Scharre, Douglas W, Kataki, Maria, Adeli, Anahita, Zimmerman, Earl A, Celmins, Dzintra, Brown, Alice D, Pearlson, Godfrey D, Blank, Karen, Anderson, Karen, Santulli, Robert B, Kitzmiller, Tamar J, Schwartz, Eben S, Sink, Kaycee M, Williamson, Jeff D, Garg, Pradeep, Watkins, Franklin, Ott, Brian R, Querfurth, Henry, Tremont, Geoffrey, Salloway, Stephen, Malloy, Paul, Correia, Stephen, Rosen, Howard J, Miller, Bruce L, Mintzer, Jacobo, Spicer, Kenneth, Bachman, David, Pasternak, Stephen, Rachinsky, Irina, Drost, Dick, Pomara, Nunzio, Hernando, Raymundo, Sarrael, Antero, Schultz, Susan K, Ponto, Laura L Boles, Shim, Hyungsub, Smith, Karen Elizabeth, Relkin, Norman, Chaing, Gloria, Raudin, Lisa, Smith, Amanda, Fargher, Kristin, Raj, Balebail Ashok, Neylan, Thomas, Grafman, Jordan, Davis, Melissa, Morrison, Rosemary, Hayes, Jacqueline, Finley, Shannon, Friedl, Karl, Fleischman, Debra, Arfanakis, Konstantinos, James, Olga, Massoglia, Dino, Fruehling, J Jay, Harding, Sandra, Peskind, Elaine R, Petrie, Eric C, Li, Gail, Yesavage, Jerome A, Taylor, Joy L, Furst, Ansgar J, Alzheimers Dis Neuroimaging In. Non-coding variability at the APOE locus contributes to the Alzheimer's risk. NATURE COMMUNICATIONS[J]. 2019, 10(1): http://gooa.las.ac.cn/external/index?type=-1&pid=1504084.
[18] Zhou, Xiaopu, Chen, Yu, Mok, Kin Y, Zhao, Qianhua, Chen, Keliang, Chen, Yuewen, Hardy, John, Li, Yun, Fu, Amy K Y, Guo, Qihao, Ip, Nancy Y, Alzheimers Dis Neuroimagi. Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer's disease pathogenesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2018, 115(8): 1697-1706, http://ir.siat.ac.cn:8080/handle/172644/13859.
[19] Chen, Yu, Liang, Zhuoyi, Fei, Erkang, Chen, Yuewen, Zhou, Xiaopu, Fang, Weiqun, Fu, WingYu, Fu, Amy K Y, Ip, Nancy Y. Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling. PLOS ONE[J]. 2015, 10(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000358621000018.
[20] Chen, Yuewen, Ip, Fanny C F, Shi, Lei, Zhang, Zhe, Tang, Huibin, Ng, Yu Pong, Ye, WenCai, Fu, Amy K Y, Ip, Nancy Y. Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton. JOURNAL OF NEUROSCIENCE[J]. 2014, 34(7): 2413-2421, https://www.webofscience.com/wos/woscc/full-record/WOS:000331614700003.
[21] Xiao, Yangui, Peng, Yinghui, Wan, Jun, Tang, Genyun, Chen, Yuewen, Tang, Jing, Ye, WenCai, Ip, Nancy Y, Shi, Lei. The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2013, 288(27): 20034-20045, http://dx.doi.org/10.1074/jbc.M113.458612.
[22] Ng, Yu Pong, Chen, Yuewen, Hu, Yueqing, Ip, Fanny C F, Ip, Nancy Y. Olean-12-Eno2,3-c 1,2,5Oxadiazol-28-Oic Acid (OEOA) Induces G(1) Cell Cycle Arrest and Differentiation in Human Leukemia Cell Lines. PLOS ONE[J]. 2013, 8(5): https://doaj.org/article/d2a3fce1d6d14454846a87c34b33b214.
[23] QiWu, JieZhang, YongShao, BoYu, YuewenChen, MingGuan, JunWan, WeiZhang. Identification of TNIP1 Polymorphisms by High Resolution Melting Analysis with Unlabelled Probe: Association with Systemic Lupus Erythematosus. HINDAWI PUBLISHING CORPORATION. 2012, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201912140951628ZK.
[24] Yu, Bo, Chen, Yuewen, Wu, Qi, Li, Ping, Shao, Yong, Zhang, Jie, Zhong, Qili, Peng, Xi, Yang, Hong, Hu, Xiaoping, Chen, Bancheng, Guan, Ming, Wan, Jun, Zhang, Wei. The association between single-nucleotide polymorphisms of NCF2 and systemic lupus erythematosus in Chinese mainland population. CLINICAL RHEUMATOLOGY[J]. 2011, 30(4): 521-527, https://www.webofscience.com/wos/woscc/full-record/WOS:000288709100011.
[25] Chen, Yuewen, Ye, Jianwei, Cao, Lingzhi, Zhang, Yong, Xia, Weibo, Zhu, Dahai. Myostatin regulates glucose metabolism via the AMP-activated protein kinase pathway in skeletal muscle cells. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY[J]. 2010, 42(12): 2072-2081, https://www.webofscience.com/wos/woscc/full-record/WOS:000284742100024.
[26] Chen, Yuewen, Cao, Lingzhi, Ye, Jianwei, Zhu, Dahai. Upregulation of myostatin gene expression in streptozotocin-induced type 1 diabetes mice is attenuated by insulin. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2009, 388(1): 112-116, https://www.webofscience.com/wos/woscc/full-record/WOS:000274534200022.
[27] Yu, Bo, Shao, Yong, Zhang, Chao, Chen, Yuewen, Zhong, Qili, Zhang, Jie, Yang, Hong, Zhang, Wei, Wan, Jun. BS69 undergoes SUMO modification and plays an inhibitory role in muscle and neuronal differentiation. EXPERIMENTAL CELL RESEARCH[J]. 2009, 315(20): 3543-3553, http://dx.doi.org/10.1016/j.yexcr.2009.09.011.
[28] Xiao Yangui, Peng Yinghui, Wan Jun, Tang Genyun, Chen Yuewen, Tang Jing, Ye Wen-Cai, Ip Nancy Y., Shi Lei. The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics *. THE JOURNAL OF BIOLOGICAL CHEMISTRY. 288(27): 20034-20045, http://dx.doi.org/10.1074/jbc.M113.458612.

   

（ 1 ） Coronin 2B介导的肌动蛋白动态变化调控神经元极性分化的分子机制研究, 主持, 国家级, 2015-01--2017-12
（ 2 ） 阿尔茨海默症的环路机制和干预措施研究, 参与, 省级, 2015-12--2018-12
（ 3 ） 阿尔茨海默症的诊治方法研究, 参与, 省级, 2018-12--2022-12
（ 4 ） Coronin 2B调控核糖体RNA转录机制及其在神经树突发育中的功能, 主持, 省级, 2019-10--2022-09
（ 5 ） 中国人群阿尔茨海默症多维度生物标志物综合研究, 参与, 国家级, 2019-08--2022-07

现指导学生

陈静  硕士研究生  071008-发育生物学