基本信息
余军平  女  硕导  中国科学院武汉病毒研究所
电子邮件: yujp@wh.iov.cn
通信地址: 湖北武汉武昌区小洪山中区44号武汉病毒所
邮政编码: 430071

研究领域

主要感兴趣的研究方向为纳米技术(原子力显微镜、纳米材料等)在生命科学中的应用(如病毒组装机理研究、高灵敏分子生物传感器等)、病原微生物检测与耐药性分析新方法研究。

招生信息

   
招生专业
071005-微生物学
招生方向
生物纳米技术,病原检测

教育背景

2004-09--2007-07   中国科学院化学研究所   理学博士
2001-09--2004-07   武汉大学   理学硕士
1997-09--2001-07   中国地质大学   工学学士

工作经历

   
工作简历
2011-08~现在, 中国科学院武汉病毒研究所, 副研究员
2010-07~2011-08,中国科学院武汉病毒研究所, 助理研究员
2007-07~2010-07,美国内布拉斯加大学医学中心, 博士后研究人员

专利与奖励

   
奖励信息
(1) 第三届武汉市优秀学术论文, 三等奖, 市地级, 2013
专利成果
[1] 危宏平, 余军平, 熊东彦, 张晓旭, 史孟娟. 一种检测新型冠状病毒Alpha和Delta突变体试剂盒及应用. CN: CN113755644A, 2021-12-07.
[2] 危宏平, 杨航, 李唱唱, 余军平, 蒋梦薇. 一种具有广谱裂解活性的抗菌肽P104、裂解酶LysP53及其应用. CN: CN113549610A, 2021-10-26.
[3] 位灯国, 杨航, 罗德华, 危宏平, 刘思思, 余军平, 沈薇, 李小红, 高超, 洪伟. 卟啉类化合物在制备抗冠状病毒药物中的应用. CN: CN112315959A, 2021-02-05.
[4] 危宏平, 余军平, 熊进. 一种MERS RNA核酸参考品的制备方法. CN: CN111154779A, 2020-05-15.
[5] 危宏平, 刘欢, 余军平, 熊进. 检测非洲猪瘟病毒感染性的PCR引物和探针、试剂盒及检测方法. CN: CN110894556A, 2020-03-20.
[6] 危宏平, 余军平, 熊进. 制备慢病毒颗粒包装EBOVRNA作为EBOV核酸检测阳性参考品的方法. CN: CN110669793A, 2020-01-10.
[7] 危宏平, 余军平, 李俊花. 一种血清中梅毒螺旋体抗体的快速检测方法及其应用. CN: CN110456052A, 2019-11-15.
[8] 危宏平, 熊东彦, 张晓旭, 余军平, 熊进, 蒋梦薇. 一种利用生信技术挖掘ASFV核酸检测序列的方法. CN: CN110364225A, 2019-10-22.
[9] 危宏平, 余军平, 罗俊. 一种血清中鲍曼不动杆菌的快速鉴定方法及其应用. CN: CN108842006A, 2018-11-20.
[10] 危宏平, 余军平, 熊进, 张晓旭. 一种抗血清干扰Taq DNA聚合酶及其制备和应用. CN: CN108070577A, 2018-05-25.
[11] 危宏平, 滕铁山, 杨航, 余军平. 一株能够产生细菌素的分散泛菌及其筛选方法和应用. CN: CN104531572A, 2015-04-22.
[12] 危宏平, 胡伟, 杨航, 余军平. 基于金黄色葡萄球菌的生物探针、制备方法及其应用. CN: CN104198737A, 2014-12-10.
[13] 危宏平, 杨航, 张云, 余军平, 张先恩. 一种杀灭葡萄球菌的裂解酶及其应用. CN: CN103122347A, 2013-05-29.
[14] 危宏平, 李恒, 周满, 耿学磊, 王殿冰, 余军平, 张先恩. 临床样本中结核分枝杆菌及吡嗪酰胺耐药性联合检测方法. CN: CN102925554A, 2013-02-13.

出版信息

   
发表论文
[1] Zhou, Wenhao, He, Ping, Li, Junhua, Liu, Huan, Shi, Mengjuan, Yu, Junping, Wei, Hongping. Steep Decline in Binding Capability of SARS-CoV-2 Omicron Variant (B.1.1.529) RBD to the Antibodies in Early COVID-19 Convalescent Sera and Inactivated Vaccine Sera. VIRUSES-BASEL[J]. 2022, 14(2): http://dx.doi.org/10.3390/v14020335.
[2] Dongyan Xiong, Xiaoxu Zhang, Junping Yu, Hongping Wei. Distribution of intra‐host variations and mutations in the genomes of SARS‐CoV‐2 and their implications on detection and therapeutics. MEDCOMM[J]. 2022, 3(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9717708/.
[3] Wenhao Zhou, Ping He, Huan Liu, Hongping Wei, Junping Yu. A luciferase based automated assay for rapid and sensitive detection of SARS-CoV-2 antibodies. ANALYTICA CHIMICA ACTA[J]. 2022, 1238: 340633-340633, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672313/.
[4] Zhang, Xinghai, Chen, Shaohong, Cao, Zengguo, Yao, Yanfeng, Yu, Junping, Zhou, Junhui, Gao, Ge, He, Ping, Dong, Zhuo, Zhong, Jie, Luo, Jing, Wei, Hongping, Zhang, Huajun. Increased pathogenicity and aerosol transmission for one SARS-CoV-2 B.1.617.2 Delta variant over the wild-type strain in hamsters. VIROLOGICA SINICA[J]. 2022, 37(6): 796-803, http://dx.doi.org/10.1016/j.virs.2022.09.008.
[5] Liu, Huan, Meng, Fei, Nyaruaba, Raphael, He, Ping, Hong, Wei, Jiang, Mengwei, Liu, Dongqing, Zhou, Wenhao, Bai, Dan, Yu, Junping, Wei, Hongping. A triton X-100 assisted PMAxx-qPCR assay for rapid assessment of infectious African swine fever virus. FRONTIERS IN MICROBIOLOGY[J]. 2022, 13: http://dx.doi.org/10.3389/fmicb.2022.1062544.
[6] Luo, Jun, Liu, Min, Wang, Peng, Li, Qianyuan, Luo, Chunhua, Wei, Hongping, Hu, Yuanyuan, Yu, Junping. Evaluation of a direct phage DNA detection-based Taqman qPCR methodology for quantification of phage and its application in rapid ultrasensitive identification of Acinetobacter baumannii. BMC INFECTIOUS DISEASES[J]. 2022, 22(1): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000807499500001.
[7] Xiong, Dongyan, Muema, Caroline, Zhang, Xiaoxu, Pan, Xinming, Xiong, Jin, Yang, Hang, Yu, Junping, Wei, Hongping. Enriched Opportunistic Pathogens Revealed by Metagenomic Sequencing Hint Potential Linkages between Pharyngeal Microbiota and COVID-19. VIROLOGICA SINICA[J]. 2021, 36(5): 924-933, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114661/.
[8] Khan, Fazal Mehmood, Gondil, Vijay Singh, Li, Changchang, Jiang, Mengwei, Li, Junhua, Yu, Junping, Wei, Hongping, Yang, Hang. A Novel Acinetobacter baumannii Bacteriophage Endolysin LysAB54 With High Antibacterial Activity Against Multiple Gram-Negative Microbes. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY[J]. 2021, 11: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960757/.
[9] Nyaruaba, Raphael, Li, Xiaohong, Mwaliko, Caroline, Li, Changchang, Mwau, Matilu, Odiwour, Nelson, Muturi, Elishiba, Muema, Caroline, Li, Junhua, Yu, Junping, Wei, Hongping. Two-Step Reverse Transcription Droplet Digital PCR Protocols for SARS-CoV-2 Detection and Quantification. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS[J]. 2021, http://dx.doi.org/10.3791/62295.
[10] Li, Changchang, Jiang, Mengwei, Khan, Fazal Mehmood, Zhao, Xiaowei, Wang, Guanhua, Zhou, Wanli, Li, Junhua, Yu, Junping, Li, Yuhong, Wei, Hongping, Yang, Hang. Intrinsic Antimicrobial Peptide Facilitates a New Broad-Spectrum Lysin LysP53 to Kill Acinetobacter baumannii In Vitro and in a Mouse Burn Infection Model. ACS INFECTIOUS DISEASES[J]. 2021, 7(12): 3336-3344, http://dx.doi.org/10.1021/acsinfecdis.1c00497.
[11] Lu, Bo, Yan, Yi, Dong, Liting, Han, Lingling, Liu, Yawei, Yu, Junping, Chen, Jianjun, Yi, Danyang, Zhang, Meiling, Deng, Xin, Wang, Chao, Wang, Runkun, Wang, Dengpeng, Wei, Hongping, Liu, Di, Yi, Chengqi. Integrated characterization of SARS-CoV-2 genome, microbiome, antibiotic resistance and host response from single throat swabs. CELL DISCOVERY[J]. 2021, 7(1): https://doaj.org/article/5bf9b36cf827428a89748b3bdd3c53a2.
[12] Nyaruaba, Raphael, Li, Changchang, Mwaliko, Caroline, Mwau, Matilu, Odiwuor, Nelson, Muturi, Elishiba, Muema, Caroline, Xiong, Jin, Li, Junhua, Yu, Junping, Wei, Hongping. Developing multiplex ddPCR assays for SARS-CoV-2 detection based on probe mix and amplitude based multiplexing. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS[J]. 2021, 21(1): 119-129, http://dx.doi.org/10.1080/14737159.2021.1865807.
[13] Xiong, Dongyan, Zhang, Xiaoxu, Xiong, Jin, Yu, Junping, Wei, Hongping. Rapid genome-wide sequence typing of African swine fever virus based on alleles. VIRUS RESEARCH[J]. 2021, 297: http://dx.doi.org/10.1016/j.virusres.2021.198357.
[14] Zhang, Xiaoxu, Xiong, Dongyan, Yu, Junping, Yang, Hang, He, Ping, Wei, Hongping. Genetic Polymorphism Drives Susceptibility Between Bacteria and Bacteriophages. FRONTIERS IN MICROBIOLOGY[J]. 2021, 12: http://dx.doi.org/10.3389/fmicb.2021.627897.
[15] Nyaruaba, Raphael, Xiong, Jin, Mwaliko, Caroline, Wang, Nuo, Kibii, Belindah J, Yu, Junping, Wei, Hongping. Development and Evaluation of a Single Dye Duplex Droplet Digital PCR Assay for the Rapid Detection and Quantification of Mycobacterium tuberculosis. MICROORGANISMS[J]. 2020, 8(5): https://www.webofscience.com/wos/woscc/full-record/WOS:000540222300082.
[16] Kering, Kelvin K, Zhang, Xiaoxu, Nyaruaba, Raphael, Yu, Junping, Wei, Hongping. Application of Adaptive Evolution to Improve the Stability of Bacteriophages during Storage. VIRUSES-BASEL[J]. 2020, 12(4): http://dx.doi.org/10.3390/v12040423.
[17] Hu, Wei, Yang, Hang, Yu, Junping, Wei, Hongping. A Novel Double Core-Shell Bionanoparticle Formed by Ferritin and Baculoviral Polyhedrin. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY[J]. 2019, 19(11): 7502-7506, https://www.webofscience.com/wos/woscc/full-record/WOS:000475752300083.
[18] Zhou, Donggen, Li, Yunpeng, Li, Junhua, Yu, Junping, Yang, Hang, Wei, Hongping. Construction of Lentivirus-Based Reference Material for RT-PCR Detection of Middle East Respiratory Syndrome Coronavirus and Its Application in External Quality Assessment. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY[J]. 2019, 19(9): 5510-5516, [19] Tao Jia, ZhiHang Chen, Peng Guo, Junping Yu. An insight into DNA binding properties of newly designed cationic δ,δ′‑diazacarbazoles: Spectroscopy, AFM imaging and living cells staining studies. SPECTROCHIMICA ACTA PART A: MOLECULAR AND BIOMOLECULAR SPECTROSCOPY[J]. 2019, 211: 260-271, http://dx.doi.org/10.1016/j.saa.2018.12.013.
[20] Zhang, Yun, Tan, Wenqing, Zhang, Yang, Mao, Huili, Shi, Shuyou, Duan, Liangwei, Wang, Hui, Yu, Junping. Ultrasensitive and selective detection of Staphylococcus aureus using a novel IgY-based colorimetric platform. BIOSENSORS & BIOELECTRONICS[J]. 2019, 142: http://dx.doi.org/10.1016/j.bios.2019.111570.
[21] Muturi, Peter, Yu, Junping, Maina, Alice Nyambura, Kariuki, Samuel, Mwaura, Francis B, Wei, Hongping. Bacteriophages Isolated in China for the Control of Pectobacterium carotovorum Causing Potato Soft Rot in Kenya. VIROLOGICA SINICA[J]. 2019, 34(3): 287-294, https://www.webofscience.com/wos/woscc/full-record/WOS:000473239500008.
[22] 周冬根, 李云鹏, 罗洁, 李军花, 余军平, 危宏平. 用于MERS-CoV核酸检测的假病毒阳性对照品制备及鉴定. 中国国境卫生检疫杂志[J]. 2019, 233-238, http://lib.cqvip.com/Qikan/Article/Detail?id=71748774504849574852484850.
[23] Yun Zhang, Wenqing Tan, Yang Zhang, Huili Mao, Shuyou Shi, Liangwei Duan, Hui Wang, Junping Yu. Ultrasensitive and selective detection of Staphylococcus aureus using a novel IgY-based colorimetric platform. BIOSENSORS AND BIOELECTRONICS[J]. 2019, 142: http://dx.doi.org/10.1016/j.bios.2019.111570.
[24] Jia, Tao, Chen, ZhiHang, Guo, Peng, Yu, Junping. An insight into DNA binding properties of newly designed cationic delta,delta '-diazacarbazoles: Spectroscopy, AFM imaging and living cells staining studies. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY[J]. 2019, 211: 260-271, http://www.corc.org.cn/handle/1471x/2373192.
[25] Luo, Jun, Jiang, Mengwei, Xiong, Jin, Li, Junhua, Zhang, Xiaoxu, Wei, Hongping, Yu, Junping. Exploring a phage-based real-time PCR assay for diagnosing Acinetobacter baumannii bloodstream infections with high sensitivity. ANALYTICA CHIMICA ACTA[J]. 2018, 1044: 147-153, http://dx.doi.org/10.1016/j.aca.2018.09.038.
[26] Yang, Hang, Xu, Jingjing, Li, Wuyou, Wang, Shujuan, Li, Junhua, Yu, Junping, Li, Yuhong, Wei, Hongping. Staphylococcus aureus virulence attenuation and immune clearance mediated by a phage lysin-derived protein. EMBO JOURNAL[J]. 2018, 37(17): https://www.webofscience.com/wos/woscc/full-record/WOS:000443413000003.
[27] Luo, Jun, Yu, Junping, Yang, Hang, Wei, Hongping. Parallel susceptibility testing of bacteria through culture-quantitative PCR in 96-well plates. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES[J]. 2018, 70: 86-92, http://www.corc.org.cn/handle/1471x/2373266.
[28] Wei, Cuihua, Liu, Junli, Maina, Alice Nyambura, Mwaura, Francis B, Yu, Junping, Yan, Chenghui, Zhang, Ruofang, Wei, Hongping. Developing a bacteriophage cocktail for biocontrol of potato bacterial wilt. VIROLOGICA SINICA[J]. 2017, 32(6): 476-484, http://www.corc.org.cn/handle/1471x/2373344.
[29] Luo, Jun, Li, Junhua, Yang, Hang, Yu, Junping, Wei, Hongping. Accurate Detection of Methicillin-Resistant Staphylococcus aureus in Mixtures by Use of Single-Bacterium Duplex Droplet Digital PCR. JOURNAL OF CLINICAL MICROBIOLOGY[J]. 2017, 55(10): 2946-2955, http://www.corc.org.cn/handle/1471x/2373390.
[30] Zhang, Yun, Yan, Chenghui, Yang, Hang, Yu, Junping, Wei, Hongping. Rapid and selective detection of E. coli O157:H7 combining phagomagnetic separation with enzymatic colorimetry. FOOD CHEMISTRY[J]. 2017, 234: 332-338, http://www.corc.org.cn/handle/1471x/2373422.
[31] Yan, Chenghui, Zhang, Yun, Yang, Hang, Yu, Junping, Wei, Hongping. Combining phagomagnetic separation with immunoassay for specific, fast and sensitive detection of Staphylococcus aureus. TALANTA[J]. 2017, 170: 291-297, http://www.corc.org.cn/handle/1471x/2373429.
[32] Yang, Hang, Zhang, Huaidong, Wang, Jing, Yu, Junping, Wei, Hongping. A novel chimeric lysin with robust antibacterial activity against planktonic and biofilm methicillin-resistant Staphylococcus aureus. SCIENTIFIC REPORTS[J]. 2017, 7: http://www.corc.org.cn/handle/1471x/2373482.
[33] Zhang Yun, Yan Chenghui, Yang Hang, Yu Junping, Wei Hongping. Rapid and selective detection of E. coli O157:H7 combining phagomagnetic separation with enzymatic colorimetry. FOOD CHEMISTRY[J]. 2017, [34] Hu, Yuanyuan, Yang, Hang, Wang, Jing, Zhang, Yun, Yu, Junping, Wei, Hongping. Comparison between a chimeric lysin ClyH and other enzymes for extracting DNA to detect methicillin resistant Staphylococcus aureus by quantitative PCR. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY[J]. 2016, 32(1): http://dx.doi.org/10.1007/s11274-015-1971-6.
[35] Junping Yu, Yun Zhang, Yun Zhang, Heng Li, Hang Yang, Hongping Wei. Sensitive and rapid detection of staphylococcus aureus in milk via cell binding domain of lysin. BIOSENSORS AND BIOELECTRONICS[J]. 2016, 77: 366-371, http://dx.doi.org/10.1016/j.bios.2015.09.058.
[36] Qiao, Jinjuan, Li, Yunpeng, Wei, Cuihua, Yang, Hang, Yu, Junping, Wei, Hongping. Rapid detection of viral antibodies based on multifunctional Staphylococcus aureus nanobioprobes. ENZYME AND MICROBIAL TECHNOLOGY[J]. 2016, 95: 94-99, http://dx.doi.org/10.1016/j.enzmictec.2016.09.006.
[37] Zhang, Yun, Yang, Hang, Yu, Junping, Wei, Hongping. Rapid and sensitive detection of HIV-1 p24 antigen by immunomagnetic separation coupled with catalytic fluorescent immunoassay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2016, 408(22): 6115-6121, http://www.corc.org.cn/handle/1471x/2375615.
[38] Huang, Yanling, Yang, Hang, Yu, Junping, Wei, Hongping. Molecular dissection of phage lysin PlySs2: integrity of the catalytic and cell wall binding domains is essential for its broad lytic activity. VIROLOGICA SINICA[J]. 2015, 30(1): 45-51, http://lib.cqvip.com/Qikan/Article/Detail?id=90666888504849534849484856.
[39] Liu, Jianli, Zhang, Xuejie, Yang, Hang, Yuan, Jinghe, Wei, Hongping, Yu, Junping, Fang, Xiaohong. Study of the interactions between endolysin and bacterial peptidoglycan on S. aureus by dynamic force spectroscopy. NANOSCALE[J]. 2015, 7(37): 15245-15250, http://ir.iccas.ac.cn/handle/121111/28407.
[40] 杨航, 余军平, 危宏平. 裂解酶治疗的研究进展与应用前景. 微生物学通报[J]. 2015, 42(1): 178-184, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5342129&detailType=1.
[41] Tieshan Teng, Junping Yu, Hang Yang, Hongping Wei. Isolation and complete genome sequence of a novel virulent mycobacteriophage, CASbig. 中国病毒学:英文版[J]. 2015, 76-79, http://lib.cqvip.com/Qikan/Article/Detail?id=90666888504849534849484953.
[42] Dong, Qiuhua, Wang, Jing, Yang, Hang, Wei, Cuihua, Yu, Junping, Zhang, Yun, Huang, Yanling, Zhang, XianEn, Wei, Hongping. Construction of a chimeric lysin Ply187N-V12C with extended lytic activity against staphylococci and streptococci. MICROBIAL BIOTECHNOLOGY[J]. 2015, 8(2): 210-220, https://www.webofscience.com/wos/woscc/full-record/WOS:000350345300002.
[43] Yang, Hang, Wang, Mengyue, Yu, Junping, Wei, Hongping. Aspartate inhibits Staphylococcus aureus biofilm formation. FEMS MICROBIOLOGY LETTERS[J]. 2015, 362(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000356888200004.
[44] Yang, Hang, Wang, Mengyue, Yu, Junping, Wei, Hongping. Antibacterial Activity of a Novel Peptide-Modified Lysin Against Acinetobacter baumannii and Pseudomonas aeruginosa. FRONTIERS IN MICROBIOLOGY[J]. 2015, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000367000200001.
[45] Teng, Tieshan, Yu, Junping, Yang, Hang, Wei, Hongping. Isolation and complete genome sequence of a novel virulent mycobacteriophage, CASbig. VIROLOGICA SINICA[J]. 2015, 30(1): 76-79, http://lib.cqvip.com/Qikan/Article/Detail?id=90666888504849534849484953.
[46] Hu, Wei, Zhang, Yun, Yang, Hang, Yu, Junping, Wei, Hongping. Simple and rapid preparation of red fluorescence and red color S. aureus derived nanobioparticles for pathogen detection. JOURNAL OF MICROBIOLOGICAL METHODS[J]. 2015, 115: 47-53, http://dx.doi.org/10.1016/j.mimet.2015.04.018.
[47] Jia, Tao, Wang, Jing, Guo, Peng, Yu, Junping. Characterizations of cationic gamma-carbolines binding with double-stranded DNA by spectroscopic methods and AFM imaging. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2015, 13(4): 1234-1242, https://www.webofscience.com/wos/woscc/full-record/WOS:000347229500032.
[48] Yang, Hang, Linden, Sara B, Wang, Jing, Yu, Junping, Nelson, Daniel C, Wei, Hongping. A chimeolysin with extended-spectrum streptococcal host range found by an induced lysis-based rapid screening method. SCIENTIFIC REPORTS[J]. 2015, 5: https://www.webofscience.com/wos/woscc/full-record/WOS:000365383800001.
[49] Huang, Li, Hu, Xiumei, Zhou, Man, Yang, Yinmei, Qiao, Jinjuan, Wang, Dianbing, Yu, Junping, Cui, Zongqiang, Zhang, Zhiping, Zhang, XianEn, Wei, Hongping. Rapid Detection of New Delhi Metallo-beta-Lactamase Gene and Variants Coding for Carbapenemases with Different Activities by Use of a PCR-Based In Vitro Protein Expression Method. JOURNAL OF CLINICAL MICROBIOLOGY[J]. 2014, 52(6): 1947-1953, https://www.webofscience.com/wos/woscc/full-record/WOS:000337919500020.
[50] Qiao, Jinjuan, Yu, Junping, Yang, Hang, Wei, Hongping. PCR-Based In Vitro Synthesis of Hepatitis C Virus NS3 Protease for Rapid Phenotypic Resistance Testing of Protease Inhibitors. JOURNAL OF CLINICAL MICROBIOLOGY[J]. 2014, 52(4): 1139-1145, http://202.127.146.157/handle/2RYDP1HH/3931.
[51] Yang, Hang, Yu, Junping, Wei, Hongping. Engineered bacteriophage lysins as novel anti-infectives. FRONTIERS IN MICROBIOLOGY[J]. 2014, 5: https://doaj.org/article/8128f0549fed465ca707aa3a0664af23.
[52] Li, Heng, Chen, Jun, Zhou, Man, Geng, Xuelei, Yu, Junping, Wang, Weihua, Zhang, XianEn, Wei, Hongping. Rapid Detection of Mycobacterium tuberculosis and Pyrazinamide Susceptibility Related to pncA Mutations in Sputum Specimens through an Integrated Gene-to-Protein Function Approach. JOURNAL OF CLINICAL MICROBIOLOGY[J]. 2014, 52(1): 260-267, https://www.webofscience.com/wos/woscc/full-record/WOS:000329222400037.
[53] Yang, Hang, Zhang, Yun, Yu, Junping, Huang, Yanling, Zhang, XianEn, Wei, Hongping. Novel Chimeric Lysin with High-Level Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus In Vitro and In Vivo. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY[J]. 2014, 58(1): 536-542, https://www.webofscience.com/wos/woscc/full-record/WOS:000329581100068.
[54] Li, Fengyun, Yu, Junping, Zhang, Zhiping, Cui, Zongqiang, Wang, Dianbing, Wei, Hongping, Zhang, XianEn. Use of hGluc/tdTomato pair for sensitive BRET sensing of protease with high solution media tolerance. TALANTA[J]. 2013, 109: 141-146, http://dx.doi.org/10.1016/j.talanta.2013.02.007.
[55] Jia, Tao, Xiang, Jin, Wang, Jing, Guo, Peng, Yu, Junping. Interactions of newly designed dicationic carbazole derivatives with double-stranded DNA: syntheses, binding studies and AFM imaging. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2013, 11(33): 5512-5520, https://www.webofscience.com/wos/woscc/full-record/WOS:000323141800015.
[56] Liu, Qingye, He, Meng, Xu, Xiaojuan, Zhang, Lina, Yu, Junping. Self-assembly of graphene oxide on the surface of aluminum foil. NEW JOURNAL OF CHEMISTRY[J]. 2013, 37(1): 181-187, https://www.webofscience.com/wos/woscc/full-record/WOS:000312485900021.
[57] Wang, Yue, Wang, Fang, Yu, JunPing, Jiang, FengChao, Guan, XinLei, Wang, CanMing, Li, Lei, Cao, Hui, Li, MingXing, Chen, JianGuo. Novel multipotent phenylthiazole-tacrine hybrids for the inhibition of cholinesterase activity, beta-amyloid aggregation and Ca2+ overload. BIOORGANIC & MEDICINAL CHEMISTRY[J]. 2012, 20(21): 6513-6522, [58] Yang, Hang, Wang, DianBing, Dong, Qiuhua, Zhang, Zhiping, Cui, Zongqiang, Deng, Jiaoyu, Yu, Junping, Zhang, Xianen, Wei, Hongping. Existence of Separate Domains in Lysin PlyG for Recognizing Bacillus anthracis Spores and Vegetative Cells. ANTIMICROBIALAGENTSANDCHEMOTHERAPY[J]. 2012, 56(10): 5031-5039, http://dx.doi.org/10.1128/AAC.00891-12.
[59] Yu, Junping, Guan, Mirong, Li, Fengyun, Zhang, Zhiping, Wang, Chunru, Shu, Chunying, Wei, Hongping, Zhang, XianEn. Effects of fullerene derivatives on bioluminescence and application for protease detection. CHEMICAL COMMUNICATIONS[J]. 2012, 48(89): 11011-11013, https://www.webofscience.com/wos/woscc/full-record/WOS:000309840400023.
[60] Li, Fengyun, Yu, Junping, Zhang, Zhiping, Cui, Zongqiang, Wang, Dianbing, Wei, Hongping, Zhang, XianEn. Buffer enhanced bioluminescence resonance energy transfer sensor based on Gaussia luciferase for in vitro detection of protease. ANALYTICA CHIMICA ACTA[J]. 2012, 724: 104-110, http://dx.doi.org/10.1016/j.aca.2012.02.047.
[61] Liu, Qingye, Xu, Xiaojuan, Zhang, Lina, Yu, Junping. Interaction between polydeoxyadenylic acid and beta-glucan from Lentinus edodes. EUROPEAN POLYMER JOURNAL[J]. 2012, 48(7): 1329-1338, https://www.webofscience.com/wos/woscc/full-record/WOS:000306681200021.
[62] Wu, Zhiguo, Tian, Tian, Yu, Junping, Weng, Xiaocheng, Liu, Yi, Zhou, Xiang. Formation of Sequence-Independent Z-DNA Induced by a Ruthenium Complex at Low Salt Concentrations. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2011, 50(50): 11962-11967, http://www.corc.org.cn/handle/1471x/2376020.
[63] Junping Yu. Nanoprobing of α-synuclein misfolding and aggregation with AFM. Nanomedicine. 2011, [64] Lyubchenko, Yuri L, Kim, BoHyun, Krasnoslobodtsev, Alexey V, Yu, Junping. Nanoimaging for protein misfolding diseases. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGYnull. 2010, 2(5): 526-543, https://www.webofscience.com/wos/woscc/full-record/WOS:000281456300007.
[65] Junping Yu. Early Stages for Parkinsons Development aSynuclein Misfolding and Aggregation. J Neuroimmune Pharmacol. 2009, [66] Junping Yu. a-Synuclein Misfolding: Single Molecule AFM Force Spectroscopy Study. J. Mol. Biol.. 2008, 
发表著作
MOLECULAR DETECTION OF ANIMAL VIRAL PATHOGENS: Chapter 58 Marburg Virus, CRC PRESS, 2016-03, 第 1 作者

科研活动

   
科研项目
( 1 ) 病毒衣壳蛋白自组装的AFM 单分子力谱研究, 主持, 国家级, 2012-01--2014-12
( 2 ) 新功能人造生物器件的构建与集成, 主持, 国家级, 2011-01--2016-12
( 3 ) 原子力显微镜研究铜绿假单胞菌噬菌体的结合与感染, 主持, 国家级, 2016-01--2019-12
( 4 ) 重要烈性病毒防控关键技术及产品研发, 参与, 部委级, 2016-01--2018-12
参与会议
(1)开发新型BRET传感器用于蛋白酶的高灵敏检测   第29届中国化学会年会   余军平,李风云,舒春英,危宏平   2014-08-04
(2)溶液增强Gaussia荧光素酶的BRET传感器检测蛋白酶   第28届中国化学会年会   李风云,余军平,张治平,崔宗强,王殿冰,危宏平,张先恩   2012-04-13
(3)The Effects of Cations on alpha-Synuclein Misfolding: Single Molecule AFM Force Spectroscopy Study   Junping Yu, Yuri L. Lyubchenko   2009-03-04
(4)alpha-Synuclein Misfolding: Single Molecule AFM Force Spectroscopy Study   Junping Yu, Sarka Malkova, Yuri L. Lyubchenko   2008-10-07

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