基本信息 Personal info

喻子牛, 男, 博导, 南海海洋研究所
http://www.scsio.ac.cn/
研究员(二级)
电子邮件(E-mail):
carlzyu@scsio.ac.cn
通信地址 (Address):
广州市新港西路164号
邮政编码 (Zip Code):
510301 
网页(Website):
http://people.ucas.edu.cn/~carlzyu
https://www.researchgate.net/profile/Ziniu_Yu?ev=prf_highl


研究领域 Research fields

(1) 贝类遗传学与育种研究 (Genetics and Breeding Studies of Mollusks):
开发、利用微卫星、线粒体DNA等分子标记,进行遗传多样性、群体遗传结构解析、育种过程中遗传变化的监测与评价、种类鉴定等;通过连锁分析进行遗传连锁图构建。利用家系选择、群体选择、多倍体诱导及杂交等方法和分子标记进行牡蛎优良品种培育;开展南海砗磲等珍稀贝类的人工繁育、培育和人工放流增殖。
(2) 贝类功能基因与基因组学 (Gene and Genomics Studies of Mollusks):
利用各种分子生物学技术和生物信息学方法, 以及转录组、表达谱、蛋白组分析,研究性状表达的分子机理,解析基因组特征;通过性状相关的功能基因筛选、克隆、表达分析,研究其分子水平的功能和调控,为性状解析和良种培育提供可供利用的基因、基因组信息和工具。 
(3) 贝类线粒体基因组与分子系统学 (Mitochondrial Genome and Molecular Phylogenetics in Mollusks):
通过线粒体基因组测序和分析,运用分子系统学理论和方法,研究、比较贝类线粒体基因组的结构与变化、基因重排及其进化,进行种类鉴定;解析并探讨贝类种、属、科等各种类间、类群间的系统关系和地位。  
 

招生信息 Student recruitments

   
招生专业 Major
070703-海洋生物学 Marine biology
-遗传学 
  Genetics  
-分子生物学
  Molecular Biology 

070703-海洋生物学 Marine biology
招生方向 Fields
海洋生物技术
Marine Biotechnology

海洋动物遗传学与分子生物学
Genetics and Molecular Biology of Marine Animals

教育背景与所获学位 Education & Degrees earned

   
学历和学位 Education history & Degrees
1979.09-83.06, 湖南师范大学, 生物学, 学士(BSc);
1983.09-86.06, 山东大学, 发育生物学, 硕士(MSc); 
1994.09-97.06, 青岛海洋大学,  海洋生物遗传学, 博士(Ph.D). 
国外工作经历 Overseas Experience
1997.08-98.12  博士后 (Postdoctoral fellow),
    美国特拉华大学海洋学院 (College of Marine Studies, University of Delaware, USA) 
2000.09-01.02  访问学者 (Visiting scholar),
    美国新泽西州立大学海洋与海岸科学学院  (Inst. Marine & Coastal Sciences, State University of New Jersey, USA)
2001.06-04.12  高级研究助理 (Senior research associate),
    美国新泽西州立大学海洋与海岸科学学院 (Inst. Marine & Coastal Sciences, State University of New Jersey, USA)

工作经历 Work experience

1986.07-89.11 助教,青岛海洋大学水产学院;
1989.12-94.11 讲师,青岛海洋大学水产学院;
1994.12-97.11 副教授,青岛海洋大学水产学院;
1997.12-03.10 教授,青岛海洋大学水产学院;
2005.01- 现在   责任研究员,中国科学院南海海洋研究所。


社会兼职 Professional Affiliations
2015-09-24-今,世界牡蛎学会(WOS), 理事
2015-03-12-今,《Aquatic Living Receources》, 副主编
2011-04-12-今,科技部国际科技合作项目评审专家, 评审专家
2010-06-05-今,中国贝类学会, 常务理事
2008-07-08-今,中国科学院湛江海洋经济动物实验站站长, 站长
2007-10-12-今,美国甲壳贝类学会(NSA)会员 , 会员
2007-09-20-今,国家贝类产业技术研发中心<育种与繁育> 研究室岗位专家, <育种与繁育> 研究室岗位专家

专利与奖励 Patents and Awards

专利成果 Patents
1. 太平洋牡蛎EST微卫星标记的筛选方法. 发明(设计)人: 喻子牛; 王艳红
申请号: CN200710027648.8;
分类号: C12Q1/68(2006.01)I; C12N15/11(2006.01)I
授权公告号: CN100532573; 授权公告日: 2009.08.26
2. 华贵栉孔扇贝微卫星标记的构建方法. 发明(设计)人: 王艳红; 喻子牛
申请号: CN200710027648.8;
分类号: C12Q1/68(2006.01)I; C12N15/11(2006.01)I;C12P19/34(2006.01)I
授权公告号: CN100552042; 授权公告日: 2009.10.21
3. 华南沿海七种巨蛎属牡蛎的PCR-RFLP鉴别方法,发明(设计)人: 喻子牛; 夏建军
公开号:CN101130815A
4. 一种贝类凝集素基因及其应用。发明(设计)人: 陈金辉; 喻子牛; 张扬
公开号:CN 102250909 A

5.张扬,张跃环,李军,喻子牛;一种新型特异结合LPS的贝类模式识别受体LRRP;专利号: ZL 201410075253.5

6. 向志明;瞿符发;肖述;喻子牛;一种血清淀粉样蛋白A及其编码基因和应用;专利号:ZL201410084163.2

7.向志明;瞿符发;肖述;喻子牛;一种纤维胶凝蛋白及其编码基因和应用;专利号:ZL 201410137128.2;

8. 张跃环, 喻子牛, 肖述, 张扬. 一种香长杂交牡蛎新品系的培育方法. 专利号: ZL201410073712.6

9.张跃环, 喻子牛, 肖述, 张扬. 一种长杂回交牡蛎新品系的培育方法. 专利号: ZL201410073380.1

10.张跃环, 喻子牛, 肖述, 张扬. 一种香杂回交牡蛎新品系的培育方法. 专利号:ZL201410072753.3

11. 张跃环, 喻子牛, 肖述, 张扬. 一种固定牡蛎远缘杂种回交优势的育种方法. 专利号: ZL201310700355.7

12.张跃环, 喻子牛, 肖述, 张扬. 一种牡蛎种间核质互换品系的制种方法. 专利号: ZL201410072660.0


科研活动 Research activities

科研项目 Grants & Fundings 
1、NSFC-广东联合基金重点项目 近江牡蛎广盐高温耐受/适应性及高效生物矿化的基因资源发掘与分子调控研究 2013-16
2、国家973计划课题 贝类抗病和抗逆的关键基因及其网络调控机制 2010-14
3、院知识创新工程重要方向项目子课题 牡蛎养殖生产与初级生产力的关系 2009-11
4、国家公益性行业专项 贝类良种选育体系建设 2008-10
5、国家现代农业技术体系建设专项 国家贝类产业技术研发中心 2008-12
6、国家海洋生物技术863项目 香港巨牡蛎优质、高产、抗逆品种的培育 2006-10
7、中国科学院资助项目 中国科学院“****”入选者研究课题, 2005-08
8、国家自然科学基金项目 太平洋牡蛎多态EST标记开发及其基因组作图研究 2006-08
9、国家自然科学基金项目 华贵栉孔扇贝微卫星分子标记开发及连锁图构建 2008-10
10、广东省科技计划项目 近江牡蛎健康苗种规模化培育与良种选育关键技术研究 20113-15
11、广东省自然科学基金重点课题 近江牡蛎基因组和EST微卫星标记开发及连锁图构建 2009-11
12、广东省科技计划项目 近江牡蛎高生长率品种的良种选育及应用示范 2008-10。
科研项目 Grants & Fundings
1、 国家973计划课题 贝类抗病和抗逆的关键基因及其网络调控机制 2010-14
2、 院知识创新工程重要方向项目子课题 牡蛎养殖生产与初级生产力的关系 2009-11
3、 国家公益性行业专项 贝类良种选育体系建设 2008-10
4、 国家现代农业技术体系建设专项 国家贝类产业技术研发中心 2008-12
5、 国家海洋生物技术863项目 香港巨牡蛎优质、高产、抗逆品种的培育 2006-10
6、 中国科学院资助项目 中国科学院“****”入选者研究课题, 2005-08
7、 国家自然科学基金项目 太平洋牡蛎多态EST标记开发及其基因组作图研究 2006-08
8、 国家自然科学基金项目 华贵栉孔扇贝微卫星分子标记开发及连锁图构建 2008-10
9、 广东省自然科学基金重点课题 近江牡蛎基因组和EST微卫星标记开发及连锁图构建 2009-11
10、广东省科技计划项目 近江牡蛎高生长率品种的良种选育及应用示范 2008-10

合作情况 Collaborations

   
合作同行 Collaborators & Connections
Prof. Patrick M. Gaffney
Director, Marine BioSciences Program, College of Marine & Earth Studies
University of Delaware, USA 
http://www.ceoe.udel.edu/people/profile.aspx?pgaffney 

Prof. Ximing Guo
Haskin Shellfish Research Lab, Institute of Marine and Coastal Sciences
Rutgers University (The State University of New Jersey), USA
http://hsrl.rutgers.edu/people/faculty/xguo.htm

Prof. Pierre Boudry
Responsable du Laboratoire Physiologie des Invertébrés,
Physiologie et Ecophysiologie des Mollusques Marins
Ifremer - Technopole de Brest-Iroise, France
http://annuaire.ifremer.fr/cv/15809/ 

Drs. Christopher Brown, Gary Wikfirs and Judy Li 
Milford Laboratory, National Marine Fisheries Service,
NOAA, USA
http://www.nefsc.noaa.gov/aed/biotech

Prof. V. Thiyagarajan (Rajan)
School of Biological Sciences, The University of Hong Kong,
Hong Kong
http://www.biosch.hku.hk/staff/rajan/rajan.htm

Prof. Jianbo Yao
Division of Animal & Nutritional Sciences,
Davis College of Agriculture, Natural Resources and Design
West Virginia University, USA
http://reprophys.wvu.edu/faculty/yao

Prof. Dean Jerry
School of Marine and Tropical Biology
James Cook University, Australia
http://www.jcu.edu.au/mtb/research/projects/JCUDEV_014224.html

学生 Students

已指导学生

夏建军  博士研究生  070703-海洋生物学  

肖  述  博士研究生  070703-海洋生物学  

任  睿  硕士研究生  070703-海洋生物学  

徐晓东  硕士研究生  070703-海洋生物学  

付定坤  硕士研究生  070703-海洋生物学  

现指导学生

李   军  硕士研究生  070703-海洋生物学  

何小翠  硕士研究生  070703-海洋生物学  

李   路  博士研究生  070703-海洋生物学  

周国伟  博士研究生  070703-海洋生物学  

于   凤  硕士研究生  070703-海洋生物学  

马海涛  博士研究生  070703-海洋生物学  

李小玲  硕士研究生  430130-环境工程  

瞿符发  硕士研究生  070703-海洋生物学  

徐晓东  博士研究生  070703-海洋生物学  

研究人员 People

张   扬 (Yang Zhang) 博士(中山大学,2009),研究员 (Associate Res Professor);
   研究方向 (Research interest):贝类免疫和抗逆的分子机制研究;

肖   述 (Shu Xiao) 博士(南海海洋研究所,2010),助理研究员 (Assistant Res Professor);
   研究方向 (Research interest):贝类繁殖与育种;

向志明 (Zhiming Xiang) 博士(中山大学,2010),副研究员 (Associate Res Professor);
   研究方向  (Research interest):贝类分子生物学;

张跃环 (Yuehuan Zhang) 博士(中国海洋大学,2012),副研究员 (Assistant Res Professor);
   研究方向 (Research interest):贝类繁殖与育种;

李 军 (Dr. Jun Li) 博士(南海海洋研究所,2014),副研究员 (Assistant Res Professor); 
   研究方向 (Research interest):贝类分子生物学;

马海涛 (Haitao Ma)博士 (南海海洋研究所,2012),助理研究员 (Assistant Res Professor);
   研究方向 (Research interest):群体遗传学与繁育;


毛帆(Fan Mao)博士(南海海洋研究所,2018),助理研究员 (Assistant Res Professor);
   研究方向 (Research interest):贝类免疫和抗逆的分子机制研究;


秦艳平(Yanping Qin)博士(南海海洋研究所,2019),助理研究员 (Assistant Res Professor);

  研究方向 (Research interest):贝类繁殖与育种;

其它论文 Other papers

1. Kong, X., L. Zhang, Yu, Z.*, Y. Liu and Q. Wang, 2002, Sequencing of Ribosomal Internal Transcribed Spacer Regions and mitochondrial gene fragments in Crassostrea gigas. J. Fish. Sci. China, 9: 304-308.
2. Yu, Z.*, X. Kong and Y. Liu, 2001, Sequencing of Ribosomal Internal Transcribed Spacer Regions (ITS-1 and ITS-2) in Scallop Chlamys farreri, J. Fish. Sci. China, 8 (1): 6-9.
3. Yu, Z.*, X. Kong and Y. Liu, 2001, Comparison of sequences of mitochondrial COI gene fragment between Chinese mitten crab and Japanese mitten crab. J. Ocean Univ. Qingdao 31(6): 861-866. (In Chinese with English abstract).
4. Gaffney, P. M., E. A. Orbacz and Z. Yu, 1998, Using DCode system to identify DNA sequence variation for studies of population structure in marine organisms. 2329. Mutat. Anal. Tech Note, 4 pp.
5. Yu, Z.*, X. Kong et al., 1998, Allozyme variation in populations of Scapharca broughtonii. J. Ocean Univ. Qingdao, 28 (1): 51-58.
6. Yu, Z.*, X. Kong et al., 1997, Studies on the karyotypes of six species of flatfishes from the Yellow Sea, with special considerations of their karyotypic evolution, Proc. 4th Asian Fish. Forum (Beijing, 1995), Asian Fisheries Society, 390-394.
7. Yu, Z.*, X. Kong et al., 1997, Allozyme variation within populations of Tegillarca granosa. J. Fish. Sci. China. 4 (5): 115-21.
8. 代悦,喻子牛,赵晓霞,王庆恒,杜晓东,吴燕忠,2010,马氏珠母贝4个壳色选育系F1遗传结构的AFLP分析。基因组学与应用生物学,29 (2): 252-258.
9. 刘亚军, 孔晓瑜, 喻子牛, 2006, 栉孔扇贝(Chlamys farreri)自然群体遗传多样性的RAPD分析,海洋与湖沼 37(4): 289-296。
10. 王青,孔晓瑜,于姗姗,喻子牛,2005,十足目染色体研究进展。海洋科学,29 (6): 60-64。
11. 陈琳琳,孔晓瑜, 周立石, 喻子牛, 2005, 魁蚶核糖体DNA基因转录间隔区的序列特征, 中国水产科学,12(1):104-108。
12. 陈立梅,孔晓瑜, 喻子牛等,2005,3种蛏类线粒体DNA 16S rRNA和 COI基因片段的比较及其系统学初步研究,海洋科学,29 (8): 27-32。
13. 郭天慧,孔晓瑜, 喻子牛等,2004,三疣梭子蟹线粒体DNA 16S rRNA和 COI基因片段的比较研究,青岛海洋大学学报, 34 (1): 22-28.
14. 张留所,孔晓瑜,喻子牛,孔杰,2003,AFLP技术在水生动物遗传学研究中的应用及前景展望, 高技术通讯, 13 (148): 95-98。
15. 姜艳艳, 孔晓瑜, 喻子牛等,2003, 黄海蓝点马鲛mtDNA D-Loop序列变异分析,中国水产科学, 10 (3): 177-183.
16. 孔晓瑜, 喻子牛,刘亚军, 2001, 中华绒螯蟹ITS-1和线粒体COI基因片段研究.青岛海洋大学学报, 31 (6): 861-866.
17. 陈再忠, 喻子牛, 孔晓瑜等, 2001, 栉孔扇贝三个自然群体遗传变异初步研究.贝类论文集, IX:53-59, 海洋出版社.
18. 孔晓瑜, 喻子牛,刘亚军, 2001, 栉孔扇贝和海湾扇贝线粒体16SrRNA基因片段的序列研究.贝类论文集, 海洋出版社, IX:59-63.
19. 孔晓瑜, 刘亚军, 喻子牛, 2001, 牙鲆、石鲽和川鲽的线粒体16S rRNA基因片段的序列比较研究. 青岛海洋大学学报, 31(5): 713-717.
20. 孔晓瑜, 姜艳艳, 喻子牛, 相建海, 2001 魁蚶线粒体16S rRNA和COI基因片段序列测定及其应用前景. 海洋科学, 25(12): 46-48.
21. 杨锐,喻子牛, 孔晓瑜等,2000, 山东沿海褶牡蛎与太平洋牡蛎等位基因酶遗传变异,水产学报 24(4):130-133.
22. 孔晓瑜, 喻子牛, 刘亚军等,2000, 栉孔扇贝核糖体RNA转录间区域(ITS-2)的序列测定. 海洋科学 11:1-3.
23. 刘必谦, 戴继勋, 喻子牛.1998,巨蛎属牡砺遗传多样性研究.水产学报,23(3): 193-197.
24. 喻子牛,孔晓瑜等,1998,魁蚶等位基因酶遗传变异研究,青岛海洋大学学报.28 (1): 51-58.
25. 喻子牛,孔晓瑜等,1997,真鲷消化道的组织学和形态学研究,水产学报,21 (2): 113-119.
26. 喻子牛,孔晓瑜等,1997,同工酶电泳技术与遗传变异研究,海洋湖沼通报2:32-42.
27. 喻子牛,孔晓瑜等,1997,泥蚶等位基因酶遗传变异研究,中国水产科学,4(5): 15-21。
28. 喻子牛,杨锐, 孔晓瑜等,1997,青岛近海魁蚶群体等位基因酶遗传变异研究,海洋湖沼通报 3: 33-39.
29. 杨惠萍,王如才,郭希明, 喻子牛,1997, 栉孔扇贝四倍体诱导:细胞松弛素B阻止受精卵第一极体和第一次卵裂。青岛海洋大学学报,27(2): 164-172.
30. 喻子牛,孔晓瑜等,1995,山东近海21种经济鱼类的核型研究,中国水产科学2 (2): 1-5
31. 喻子牛,孔晓瑜等,1995,五种海水经济鱼类的染色体研究,青岛海洋大学学报26 (1): 44-48
32. 喻子牛,孔晓瑜等,1995,鱼类抗病遗传,海洋湖沼通报, 2: 63-69.
33. 喻子牛,孔晓瑜等,1995,海洋贝类多倍体操作机理与最新进展,海洋湖沼通报, 4: 72-79.
34. 孔晓瑜,喻子牛等,1995, 《中国商品大词典》水产品分册.
35. 孔晓瑜,喻子牛等,1994,鯒的核型和Ag-NOR带的研究,青岛海洋大学学报24 (3): 344-348.
36. 喻子牛,孔晓瑜等,1994,鲈鱼染色体显带的初步研究, 中国动物学会成立60年纪念论文集. 469-473。
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出版信息

   
近期发表论文 Recent Papers

 

1.         Mao F., K. Liu, Y. Lin, Z. He, J. Li, Z. Xiang, Y. Zhang* and Z. Yu*, 2020, Opsonic character of the plasma proteins in phagocytosis-dependent host response to bacterial infection in a marine invertebrate, Crassostrea gigas. Develop. Comp. Immunol. 106 :103596

2.         Zhou Z., J. Li, Y. Qin, Y. Zhou, Y. Zhang*, Z. Yu* etc., 2020, Artificial interspecific hybridization of two giant clams, Tridacna squamosa and Tridacna crocea, in the south China sea. Aquaculture, 515:734581.

3.         Liu, Y., Mao F., X. Zhang, Z. He, J. Li, Z. Xiang, Y. Zhang* and Z. Yu*, 2020, Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkongensis. Frontiers in Immunology. 11:416.

4.         Zhang, Y., H. Ma. J. Li, Z.. Zhou, Y. Qin, Z. Yu* etc., 2020, Analysis of inbreeding depression on performance traits of three giant clams (Tridacna derasa, T. squamosa, and T. crocea) in the South China Sea. Aquaculture, 521: 735023.

5.         Liu, Y., Mao F., X. Zhang, Z. He, J. Li, Z. Xiang, Y. Zhang* and Z. Yu*, 2020, TRAF6 suppresses the apoptosis of hemocytes by activating pellino in Crassostrea hongkongensis. Develop. Comp. Immunol.  103:103501.

6.         Qin, Y., Zhang, Y., H. Ma. J. Li, Z.. Zhou, Z. Yu* etc., 2020, Characterization and functional analysis of a caspase 3 gene: Evidence that ChCas 3 participates in the regulation of apoptosis in Crassostrea hongkongensis. Fish & Shellfish Immunology, 98:122-129.

7.         Zhang, Y., Y. Qin, J. Li, Z.. Zhou, S. Xiao, Z. Yu* etc., 2019, Gametogenesis From the Early History Life Stages of the Kumamoto Oyster Crassostrea sikamea and Their Breeding Potential Evaluation. Frontiers in Physiology, 5(10) :524.

8.         Ma, H., Y. Zhang, S. Xiao, Y. Zhang, Z. Xiang and Z. Yu* etc., 2019, The complete mitochondrial genome of giant clam, Hippopus hippopus (Cardiidae: Tridacninae). Conservation Genetics Resources. 11(3) : 263 -266.

9.         Wu, X., Zhang, Y., Y. Qin, S. Xiao, Z. Yu* etc., 2019, Comparative studies of the growth, survival, and reproduction of diploid and triploid Kumamoto oyster, Crassostrea sikamea.  J World Aquacult Soc. 1-12.

10.     Qin, Y., Y. Zhang, R. Mo, Y. Zhang*, Z. Yu* et al, 2019, Influence of ploidy and environment on grow-out traits of diploid and triploid Hong Kong oysters Crassostrea hongkongensis in southern China. Aquaculture, 507: 108-118.

11.     Mao F., Y. Lin, Z. He, J. Li, Z. Xiang, Y. Zhang* and Z. Yu*, 2018, Dual roles of cystatin A in the immune defense of the pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 75:190-197.

12.     Qin, Y., Zhang, Y., H. Ma. J. Li, S. Xiao, Z. Yu* etc., 2018, Comparison of the Biochemical Composition and Nutritional Quality nBetween Diploid and Triploid Hong Kong Oysters, Crassostrea hongkongensis. Frontiers in Physiology, 9 :1674.

13.     Ma, H., L. Lin, Y. Zhang, W. Shi and Z. Yu*, 2018, The complete mitochondrial genome sequence of the giant clam Tridacna derasa (Tridacnidae: Tridacna). Mitochondrial DNA Part B. https://doi.org/10.1080 /23802359.2018.

14.     Li, J., Zhang, Y., Zhang, Y., Mao F., S. Xiao, Z. Xiang, Z. Yu* et al, 2018, A Lysin motif (LysM)-containing protein from Hong Kong oyster, Crassostrea hongkongensis functions as a pattern recognition protein and an antibacterial agent. Gene, 674 :134–142.

15.    Li, J., Zhang, Y., Y. Qin, Mao F., Y. Lin, Y. Zhang, Z. Yu* et al, 2018, The first morphologic and functional characterization of hemocytes in Hong Kong oyster, Crassostrea hongkongensis. Fish & Shellfish Immunology, 81:423-429.

16.     Qin, Y., S. Xiao, H. Ma. J. Li, Y. Zhang*, Z. Yu* etc., 2018, Effects of salinity and temperature on the timing of germinal vesicle breakdown and polar body release in diploid and triploid Hong Kong oysters, Crassostrea hongkongensis, in relation to tetraploid induction. Aquaculture Research, DOI: 10.1111/are.13833.

17.     Zhang, Y., Li, J., Zhang, Y., Ma, H., Xiao, S., Xiang, X. ans Z. Yu*, (2017) Performance evaluation of reciprocal hybrids derived from the two brackish oysters, Crassostrea hongkongensis and Crassostrea sikamea in southern China. Aquaculture 473 310-316.

18.     Zhang, Y., Li, J., Qin, Y., Zhou, Y., Zhang, Y., Yu, Z*. 2017, A comparative study of the survival, growth and gonad development of the diploid and triploid Hong Kong oyster, Crassostrea hongkongensis (Lam & Morton 2003). Aquaculture Research, 48(5): 2453-2462.

19.     Zhang, Y., Zhang, Y., Li, J., Wang, Z., Yan, X., Yu, Z*.  2017, Incomplete sterility of hybrids produced by Crassostrea hongkongensis female× Crassostrea gigas male crosses. Aquaculture Research, 48(3): 1351-1358.

20.     Zhang, Y., Y. Zhang, J. Li, Z. Yu*, 2017, Morphological and molecular evidence of hybridization events between two congeneric oysters, Crassostrea hongkongensis and C. ariakensis , in southern China. J. Mollus. Stud. 83(1):123-128.

21.     Zhang, Y., Y. Zhang, J. Li, S. Xiao, Z. Xiang, Z. Wang*, X. Yan, Z. Yu*, 2016, Artificial interspecific backcrosses between the hybrid of female Crassostrea hongkongensis × male C. gigas and the two parental species. Aquaculture, 450:95-101.

22.     Zhang, Y., J. Su, J. Li, Y. Zhang, S. Xiao, Z. Yu*, 2016, Survival and growth of reciprocal crosses between two stocks of the Hong Kong oyster Crassostrea hongkongensis (Lam & Morton, 2003) in southern China. Aquaculture Research, 48:2344-2354.

23.     Zhang, Y., J. Li, Y. Qin, Y. Zhou, Y. Zhang, Z. Yu*, 2016, A comparative study of the survival, growth and gonad development of the diploid and triploid Hong Kong oyster, Crassostrea hongkongensis (Lam & Morton 2003). Aquaculture Research, 48:2353-2362.

24.     Li, J. , Y. Zhang, Y. Liu, Y. Zhang, S. Xiao, Z. Yu*, 2016, Co-expression of heat shock protein (HSP) 40 and HSP70 in Pinctada martensii response to thermal, low salinity and bacterial challenges. Fish Shellfish Immunol. 48: 239-243.

25.     Wang, F., S. Xiao, Zhang, Y., Y. Zhang, Y. Liiu, Y. Yan, Z. Xiang, Z. Yu*, 2015, ChAkt1 involvement in orchestrating the immune and heat shock responses in Crassostrea hongkongensis: Molecular cloning and functional characterization. Fish Shellfish Immunol. 4: 1015-1023.

26.     Tong, Y., Y. Zhang*, J. Huang, S. Xiao, Y. Zhang, Jun Li, J. Chen, Z. Yu*, 2015, Transcriptomics Analysis of Crassostrea hongkongensis for the Discovery of Reproduction-Related Gene. PLoS One, 10(8):e0134280.

27.     Xu, F., Y. Zhang*, J. LiY. ZhangZ. Xiang, Z. Yu, 2015, Expression and Function analysis of two Naturally Truncated MyD88 variants in the Pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 45:510-516.

28.     Xu, F., J. LiY. Zhang, X. Li, Y. Zhang*, Z. Xiang, Z. Yu*, 2015, CgIκB3, the third novel inhibitor of NF-kappa B (IκB) protein, is involved in the immune defense of the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 46:648-655.

29.     Zhang, Y., Y. Zhang, J. Li,  Z. WangX. Yan, Z. Yu*, 2015, Incomplete sterility of hybrids produced by Crassostrea hongkongensis female x Crassostrea gigas male crosses. Aquaculture Res. DOI: 10.1111/ are.12941

30.     Qu, F., Z. XiangF. WangY. ZhangJ. Li, Y. ZhangS. Xiao, Z. Yu*, 2015, Identification and function of an evolutionarily conserved signaling intermediate in Toll pathways (ECSIT) from Crassostrea hongkongensis. Develop. Comp. Immunol.

31.     Zhang, Y., Y. Zhang,  Li J.Z. Wang*, X. Yan, Z. Yu*, 2015, Phenotypic trait of Crassostrea hongkongensis♀× C. angulata♂ hybrids in southern China. Aquaculture Research, DOI:10.1111/are.12787.

32.     Qu, , F., Z. Xiang, F. Wang, Y. Zhang, Y. Tong, J. Li, Y. Zhang, Z. Yu*, 2015, A novel molluscan Fos gene with immune defense function identified in the Hong Kong oyster, Crassostrea hongkongensis. Develop. Comp. Immunol. 51:194-201.

33.     Li, J. , Y. Zhang, Y. Zhang, Y. Liu, Z. Xiang, F. Qu, Z. Yu, 2015, Cloning and characterization of three suppressors of cytokine signaling (SOCS) genes from the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 44: 525–532.

34.     Qu, F., Xiang, Z., F. Wang, L. Qi, F. Xu, S. Xiao and Z. Yu*, 2015, Prostaglandin E receptor 4 (PTGER4) involved in host protection against immune challenge in oyster, Crassostrea hongkongensis. Fish Shellfish Immunol. 42: 316–324.

35.     Xiang, Z., F. Qu, F. Wang, Y. Tong, S. Xiao, J. Li, Y. Zhang and Z. Yu*, 2015, ChBax/Bak as key regulators of the mitochondrial apoptotic pathway: Cloned and characterized in Crassostrea hongkongensis. Fish Shellfish Immunol. 42:225-232.

36.     Zhang, Y., J. Sun , H. Mu , J. Li ,Y. Zhang , F. Xu , Z. Xiang, P Y. Qian , J. W. Qiu* and Z. Yu*, 2015, Proteomic basis of stress responses in the gills of the Pacific oyster Crassostrea gigas. J. Proteome Res. 14, 304317.

37.     Zhang, Y., Y. Zhang, Z. Wang*, X. Yan and Z. Yu*, 2014, Phenotypic trait analysis of diploid and triploid hybrids from female Crassostrea hongkongensis × male C. gigas. Aquaculture 434307-314.

38.     Qu, F., Xiang Z., Zhang YLi J., Zhang YZ. Yu*, 2014, The identification of the first molluscan Akirin2 with immune defense function in the Hong Kong oyster Crassostrea hongkongensis. Fish Shellfish Immunol. 41: 455-465.

39.     Xiang, Z., F. Qu, , J. Li, F. Wang, Y. Zhang and Z. Yu*, 2014, Characteristic and functional analysis of a ficolin-like protein from the oyster Crassostrea hongkongensis. Fish Shellfish Immunol. 40: 514-523.

40.     Li, J., Y. Zhang, Y. Zhang, Z. X.iang, Y. Tong, F. Qu and Z. Yu*, 2014, Genomic characterization and expression analysis of five novel IL-17 genes in the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 40: 455-465.

41.     Zhang, Y., F. Yu, J. Li, Y. Tong, Y. Zhang and Z. Yu*, 2014, The first invertebrate RIG-I-like receptor (RLR) homolog gene in the pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 40: 466-471.

42.     Zhang, Y., J. Li, F. Yu, Y. Tong, Y. Zhang, X. Zhi and Z. Yu*, 2014, Identification and functional characterization of SIMPL in Crassostrea gigas reveals its ancient origin and involvement in the regulation of Rel/NF-κB transcription activity. Fish Shellfish Immunol. 40: 239-244.

43.     Xia, J. X. Wu, S. Xiao, Z. Yu*, 2014, Mitochondrial DNA and morphological identification of a new cupped oyster species Crassostrea dianbaiensis (Bivalvia: Ostreidae) in the South China Sea. Aquat. Living Resour. 27, 41-48.

44.     Qu, , F., Xiang, Z., Z. Yu*, 2014, The first molluscan acute phase serum amyloid A (A-SAA) identified from oyster Crassostrea hongkongensis: Molecular cloning and functional characterization. Fish Shellfish Immunol.  39 (2014) 145-151.

45.     Huang, J., Y. Zhang, J. Li, Z. Yu*, 2014, Development of SNP markers in Crassostrea hongkongensis based on the next-generation sequencing and high resolution melting analysis. Conservation Genet Resour. 6:559–562.

46.     Xiang, Z., F. Qu, L. Qi, Y. Tong, J. Li, S. Xiao, Z. Yu*, 2014, Cloning and characterization of an apoptosis-related DNA fragmentation factor (DFF) from oyster, Crassostrea hongkongensis. Fish Shellfish Immunol. 38: 119126.

47.     Wu, X., S. Xiao, Z. Yu*, 2013, Mitochondrial DNA and morphological identification of Crassostrea zhanjiangensis sp. nov. (Bivalvia: Ostreidae): a new species in Zhanjiang, China. Aquat. Living Resour. 26(4): 273-280.