基本信息
董德文  男  博导  中国科学院长春应用化学研究所
电子邮件： dwdong@ciac.ac.cn
通信地址： 长春市人民大街5625号
邮政编码： 130022

研究领域

1. 有机合成化学： （1）绿色化学， （2）杂环化合物合成方法学
2. 有机功能材料： （1）有机高分子功能材料， （2）有机/无机纳米杂化发光材料

招生信息

招收硕士、博士研究生

招生专业
070303-有机化学
招生方向
有机合成化学（1）绿色有机化学（2）杂环化合物合成方法学

教育背景

1996-09--1999-07   中国科学院长春应用化学研究所   博士
1989-09--1992-07   东北师范大学   硕士
1985-09--1989-07   东北师范大学   学士
学历
1985-1989 东北师范大学化学系，学士
1989-1992 东北师范大学化学系有机化学专业，硕士
1992-1996 中国科学院长春应用化学研究所，助理研究员
1996-1999 中国科学院长春应用化学研究所高分子化学与物理，博士
出国学习工作

1999-2001  日本静冈大学(Shizuoka University)，特别研究员、非常勤讲师
2001-2003  英国赫尔大学(The University of Hull), 博士后研究员

 

教授课程

有机化学 有机化学实验

指导学生

已指导学生

张睿  博士研究生  070303-有机化学  

向德轩  博士研究生  070303-有机化学  

周奋国  博士研究生  070303-有机化学  

张定远  博士研究生  070303-有机化学  

黄鹏  博士研究生  070303-有机化学  

刘绪  博士研究生  070303-有机化学  

王自坤  博士研究生  070303-有机化学  

信晓庆  博士研究生  070303-有机化学  

杨继明  博士研究生  070303-有机化学  

现指导学生

张倩  博士研究生  070303-有机化学  

王齐聊  硕士研究生  070303-有机化学  

侯丽曼  博士研究生  070303-有机化学  

袁静文  博士研究生  070303-有机化学  

科研活动

研究方向

1. 有机合成方法学

　　鉴于杂环类化合物在有机合成化学以及生物活性物质中发挥的重要作用，我们从简单合成前体如1,3-二羰基化合物及其具有多活性官能化结构的衍生物出发，利用维尔斯迈尔反应、有机氧化反应、过渡金属催化的缩合反应、电环化与重排反应等经典合成手段，建立系列四元、五元、六元杂环化合物的合成策略。阐明新方法中杂环构建、高效催化、绿色合成所涉及的反应机理、选择性等基本科学问题，形成新理论，为具有生物活性的杂环母核构建提供新的合成技术与理论依据。




2. 智能高分子及表面

　　致力于功能型零维、一维、二维与三维聚合物刷的设计制备、结构研究与应用探索。从功能性单体与催化剂的设计合成入手，探寻功能性单体的可控高效聚合方法，制备具有不同拓扑结构的刺激响应型聚合物，为功能聚合物材料的制备提供简便高效的制备方法的同时，也为理解材料结构与性质之间的关系提供理论与实验参考；在具有不同几何结构的有机、无机材料表面与界面，通过共价键接枝化学成分可调、结构可控的聚合物刷，建立简单高效的表面引发活性聚合方法，探索聚合物刷在功能防护、能源、催化、光电与生物医用等领域的应用。




3. 有机氟硅高分子材料

　　针对氟硅化合物的特殊使用需求，从分子设计出发，开展特种氟硅材料的分子结构设计、制备与应用研究。探索有机氟硅聚合物结构与性能的关系，通过与功能性有机高分子预聚物的接枝、共聚、复合等手段，制备新型有机氟硅材料，拓展其在阻燃、防火等领域的应用；通过分子结构单元尺寸和构型的控制，制备新型有机氟硅纳米结构材料，并开展其在催化、分子探针、多孔材料等领域的研究。




代表性研究论文

  1.   M. Yu, Q. Zhang, J. Yuan, N. Zhang,* R. Zhang, D. Dong,* Copper-Nitrene-Triggered Annulation of α-Acyl Cinnamamides: Access to Isoxazol-3(2H)-ones, Advanced Synthesis & Catalysis 2016, 358(3), 410-416.

  2.  J. Yuan, Q. Zhang, M. Yu, P. Huang,* R. Zhang, D. Dong,* Phenyliodine(III) Diacetate Mediated Oxidative Cyclizationof 1-Alkenoyl-1- Carbamoyl Cycloalkanes: Access to Spiro-Fused Dihydrofuran-3(2H)-ones, Organic Letters 2015, 17, 5012-5015.

  3.  J. Yang, D. Xiang, R. Zhang, N. Zhang,* Y. Liang, X. Xin, D. Dong,* POCl3-Mediated Reaction of 1-Acyl-1-Carbamoyl Oximes: A New Entry to Cyanoformamides, Organic Letters 2015, 17 (4), 809–811.

  4.  Q. Zhang, X. Liu, X. Xin, R. Zhang,* Y. Liang, D. Dong,* Formal [4+2] Annulation of Enaminones and Cyanomethyl Sulfur Ylide: One-pot Access to Pyridin-2(1H)-ones, Chemical Communications 2014, 50 (97), 15378 - 15380.

  5. J. Yang, L. Hou, B. Xu, N. Zhang,* Y. Liang, W. Tian, D. Dong,* Polymer brushes on planarTiO2 substrate, Macromolecular Rapid Communications2014, 35(13),1224-1229.

  6.  Z. Wang, X. Bi, Y. Liang,* P. Liao, D. Dong,* Copper-catalyzed formal O-H insertion reaction of α-diazo-1,3-dicarb- onyl compounds to carboxylic acids with the assistance of isocyanide, Chemical Communications 2014, 50, 3976–3978.

  7.  X. Xin, D. Xiang, J. Yang, Q. Zhang, F. Zhou, Dong,* Homogeneous and Stereoselective Copper(II)- Catalyzed Monohydration of Methylene-malononitriles to 2-Cyanoacrylamides, Journal of Organic Chemistry 2013, 78, 11956-11961.

  8.  F. Zhou, X. Liu, Y. Liang, R. Zhang, N. Zhang,* X. Xin, D. Dong,* Copper-catalyzed Three-component Reaction: Solvent-controlled Regioselective Synthesis of 4-Amino-and 6-Amino-2-iminopyridines, Organic Letters 2013, 15, 5786–5789.

  9. D. Zhang, Q. Zhang, R. Zhang, Y. Liang, D. Dong,*Formal [4+1] annulation of α,α-dialkyl β-oxo amides and dimethylsulfoxonium methylide: a synthetic route to β-hydroxy-γ-lactams, Chemical Communications 2013, 49,7358-7360.

  10.  X. Liu, N. Zhang, J. Yang, Y. Liang, R. Zhang,D. Dong,*Hydrogen Bond-Assisted 6π-Azaelectrocyclization of Penta-2,4-dienamides: Synthesis of Dihydropyridin-2(3H)-ones, Journal of Organic Chemistry 2013, 78, 3323-3328.

  11. (11)    X. Liu, Q. Zhang, D. Zhang, X. Xin, J. Yang, R. Zhang,F. Zhou, D. Dong,*PPA-Mediated C-C Bond Formation: a Synthetic Route to Substituted Indeno[2,1-c]quinolin-6(7H)-ones, Organic Letters 2013, 15, 776-779.

  12.  Z. Wang, X. Bi,* P. Liao, X. Liu, D. Dong,* Cu(II)-catalyzed cyclization of α-diazo-β-oxoamides with amines leading to pyrrol-3(2H)-ones, Chemical Communications 2013, 49,1309-1311.

  13. P. Huang, R. Zhang,Y. Liang,D. Dong,* [5C + 1N] Annulations: Two Novel Routes toSubstituted Dihydrofuro[3,2-c]pyridines, Organic Letters 2012, 14(20), 5196-5199.

  14. Z. Wang, X. Bi,* P. Liao, R. Zhang, Y. Liang, D. Dong,* The CatalyticWolff 1,2,3-Triazole Synthesis: Intramolecular Hydrogen Bonding-Assisted Cyclocondensation of α-Diazo-β-Oxoamides with Various Amines, Chemical Communications 2012, 48,7076-7078.

  15. D. Xiang, X. Xin, X. Liu, R. Zhang,* J. Yang, D. Dong*, Regioselective Synthesis of 3-Arylamino- and 5-Arylamino-isoxazolesfrom Enaminones, Organic Letters 2012, 14(2), 644-647.

  16. P. Huang, N. Zhang,* R. Zhang, D. Dong,* Vilsmeier-type Reaction of Dimethylaminoalkenoyl Cyclopropanes: One-pot Access to 2,3-Dihydrofuro [3,2-c]pyridine-4(5H)-ones, Organic Letters 2012, 14(1), 370-373.

  17. Y. Hu, X. Fu, B.-D. Barry, X. Bi,* D. Dong,* One-pot synthesis of N-aryl-3-spirocyclic-β-lactams and further regiospecific β-lactam ring-opening/recyclization reactions catalyzed by Lewis-Brønsted acidscombined superacid catalyst system: A new entry to 3-spirocyclicquinolin-4(1H)-ones, Chemical Communications 2012, 48, 690-692.

  18.  R. Zhang, D. Zhang,D. Dong,* Vilsmeier reaction of 3-aminopropenamides: One-pot synthesis of pyrimidin-4(3 H)-ones, Journal of Organic Chemistry 2011, 76, 2880-2883.

  19. X. Xin,Y. Wang, W. Xu, Y. Lin,H. Duan, D. Dong,* A Facile and Efficient One-Pot Synthesis of Polysubstituted Benzenes in Guanidinium Ionic Liquids, Green Chem. 2010,12, 893-898.

  20. Y. Wang, X. Xin, Y. Liang,Y. Lin,* H. Duan, D. Dong,* N,N,N’,N’-Tetramethylchloroformamidinium Chloride-Mediated Cyclizations of b-Oxo Amides: Facile and Divergent One-pot Synthesis of Substituted 2H-Pyrans, 4H-Pyrans and Pyridin-2(1H)-ones, Advanced Synthesis & Catalysis 2009, 351, 2217-2223.

  21.  K. Wang, X. Fu, J. Liu, Y. Liang, D. Dong,* PIFA-Mediated Oxidative Cyclization of 1-Carbamoyl-1-Oximylcycloalkanes: Synthesis of Spiro-Fused Pyrazolin-5-one N-oxides, Organic Letters 2009, 11, 1015-1018.

  22.  R. Zhang, D. Zhang, Y. Guo, G. Zhou, Z. Jiang, D. Dong*, Vilsmeier Reaction of Enaminones: Efficient Synthesis of Halogenated Pyridin-2(1H)-ones, Journal of Organic Chemistry 2008, 73(23), 9504-9507.

  23. D. Xiang, P. Huang, K. Wang, G. Zhou, Y. Liang, D. Dong,* Efficient and Divergent Synthesis of Cyclophosphamide Analogues from 2-Arylamino-3-acetyl-5,6-dihydro-4H-pyrans, Chemical Communications 2008, 6236-6238.

  24. R. Zhang, Y. Liang, G. Zhou, K. Wang, D. Dong,* Ring Enlargement of Dimethylaminopropenoyl Cyclopropanes: An Efficient Route to Substituted 2,3-Dihydrofurans, Journal of Organic Chemistry 2008, 73(20), 8089-8092.

  25. Y. Wang, J. Huang, Y. Chai, Q. Liu, Y. Liang, D. Dong,* Efficient One-Pot Synthesis of Highly Substituted Thiophene Library from 1,3-Dicarbonyl Compounds, Journal Combinatorial Chemistry 2008, 10(4), 511-516.

  26. K. Wang, D. Xiang, J. Liu, W. Pan, D. Dong,* Efficient and Divergent Synthesis of Fully Substituted 1H-Pyrazoles and Isoxazoles from Cyclopropyl Oximes, Organic Letters 2008, 10, 1691-1694.

  27. D. Xiang, K. Wang,Y. Liang, G. Zhou, D. Dong,* A Facile and Efficient Synthesis of Polyfunctionalized Pyridin-2(1H)-ones from b-Oxo Amides under Vilsmeier Conditions, Organic Letters 2008, 10, 345-348.

  28. (28)    J. Huang, Y. Liang, W. Pan, Y. Yang, D. Dong,*Efficient Synthesis of Highly Substituted Pyrrolin-4-ones via PIFA-Mediated Cyclization Reactions of Enaminones, Organic Letters 2007,9, 5345-5348.

  29. D. Xiang, Y. Yang, R. Zhang, Y. Liang, W. Pan,J. Huang,D. Dong,* Vilsmeier-Haack Reactions of 2-Arylamino-3-acetyl-5,6-dihydro-4H-pyrans towards the Synthesis of Highly Substituted Pyridin-2(1H)-ones, Journal of Organic Chemistry 2007,72, 8593-8596.

  30. W. Pan, D. Dong,* K. Wang, J. Zhang, R. Wu, D. Xiang,Q. Liu, Efficient One-pot Synthesis of Highly Substituted Pyridin-2(1H)-ones via the Vilsmeier-Haack Reaction of 1-Acetyl,1-Carbamoyl Cyclopropanes; Organic Letters 2007, 9, 2421-2423.

  31.  Y. Ouyang, D. Dong*, H. Yu, Y. Liang, Q. Liu, A Clean, Facile and Practical Synthesis of a-Oxo Ketene-(S,S)-acetals in Water, Advanced Synthesis& Catalysis 2006, 348(1-2), 206-210.

  32. (32)    X. Bi, D. Dong,* Q. Liu*, W. Pan, L. Zhao, B. Li, [5+1] Annulation: A New Synthetic Strategy for Highly Substituted Phenols and Cyclohexenones, Journal of American Chemical Society 2005, 127(13), 4578-4579.

  33. D. Dong*, X. Bi, Q. Liu, F. Cong, [5C + 1N] Annulation: A Novel Synthetic Strategy for Functionalized 2,3-Dihydro-4-pyridones, Chem.Commun. 2005, 28, 3580-3582.

  34. D. Dong*, Y. Ouyang, H. Yu, Q. Liu, J. Liu, M.Wang, J. Zhu, Chemoselective thioacetalization in water: 3-(1,3-dithian-2- ylidene) pentane-2,4-dione as an odorless, efficient and practical thioacetalization reagent, Journal of Organic Chemistry 2005, 70(11), 4535-4537.

  35. X. Bi, D. Dong*, Y. Li, Qun Liu, Q. Zhang, [5C + 1S] Annulation: A Facile and Efficient Synthetic Route toward Functionalized 2,3-Dihydrothiopyran-4-ones, Journal of Organic Chemistry 2005, 70(26), 10886-10889.