计算机算法，生物信息学，人工智能

博/硕士

081202-计算机软件与理论

生物信息学
人工智能
计算机算法

2002-09--2007-08   中国科学院计算技术研究所   博士
1998-10--2001-08   南开大学物理化学专业   硕士
1994-08--1998-08   南开大学物理化学专业   学士

2001.7~ 中国科学院计算技术研究所

2011-09~现在, 中国科学院计算技术研究所, 副研究员
2007-07~2011-08,中国科学院计算技术研究所, 助理研究员

生物信息学中的算法设计

2010年，中国科学院计算技术研究所 学术百星

[1] 孙世伟, 卜东波, 杨飞, 王耀军, 李岩, 黄纯翠, 陈润生, 高枫, 刘亚名. 一种糖结构鉴定方法及糖结构鉴定装置. CN: CN105758928A, 2016-07-13.

[2] 孙世伟, 王耀君, 卜东波, 李岩, 黄纯翠, 刘亚名, 杨飞, 武红梅, 陈润生. 多级质谱生物大分子结构鉴定方法. CN: CN104965020A, 2015-10-07.

[3] 卜东波, 许情, 陈挺, 孙世伟, 李帅成, 刘兴武, 张仁玉, 王超. 一种基因组酶切图谱拼接方法及系统. CN: CN104951673A, 2015-09-30.

[4] 卜东波, 张仁玉, 陈挺, 李帅成, 孙世伟, 刘兴武, 许情, 郑全刚, 王超. 一种第二代、三代基因组测序数据联用的拼接方法及系统. CN: CN104951672A, 2015-09-30.

   

[1] Haoyang Li, Juexiao Zhou, Zhongxiao Li, Siyuan Chen, Xingyu Liao, Bin Zhang, Ruochi Zhang, Yu Wang, Shiwei Sun, Xin Gao. A comprehensive benchmarking with practical guidelines for cellular deconvolution of spatial transcriptomics. NATURE COMMUNICATIONS[J]. 2023, 14(1): 1-10, https://doaj.org/article/e0ac7957a0e843a6abfe135b377de0e7.
[2] Bin Huang, Tingwen Fan, Kaiyue Wang, Haicang Zhang, Chungong Yu, Shuyu Nie, Yangshuo Qi, WeiMou Zheng, Jian Han, Zheng Fan, Shiwei Sun, Sheng Ye, Huaiyi Yang, Dongbo Bu, Lenore Cowen. Accurate and efficient protein sequence design through learning concise local environment of residues. BIOINFORMATICS[J]. 2023, 39(3): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027430/.
[3] Wenkai Han, Ningning Chen, Xinzhou Xu, Adil Sahil, Juexiao Zhou, Zhongxiao Li, Huawen Zhong, Elva Gao, Ruochi Zhang, Yu Wang, Shiwei Sun, Peter PakHang Cheung, Xin Gao. Predicting the antigenic evolution of SARS-COV-2 with deep learning. NATURE COMMUNICATIONS[J]. 2023, 14(1): 1-14, https://doaj.org/article/8ad8dabc45b5410b92bc347c1258b550.
[4] Yaojun Wang, Shiwei Sun. Revolutionizing Antibody Discovery: An Innovative AI Model for Generating Robust Libraries. Genomics, Proteomics & Bioinformatic[J]. 2023, https://doi.org/10.1016/j.gpb.2023.06.001.
[5] chuncui huang, meijie hou, jingyu yan, Wengang Chai, Yan Li, Shiwei Sun. GIPS-Mix for Accurate Identification of Isomeric Components in Glycan Mixtures Using Intelligent Group-Opting Strategy. Analytical Chemistry[J]. 2023, https://pubs.acs.org/doi/abs/10.1021/acs.analchem.2c02978.
[6] Kong, Lupeng, Ju, Fusong, Zheng, Weimou, Zhu, Jianwei, Sun, Shiwei, Xu, Jinbo, Bu, Dongbo. ProALIGN: Directly Learning Alignments for Protein Structure Prediction via Exploiting Context-Specific Alignment Motifs. JOURNAL OF COMPUTATIONAL BIOLOGY. 2022, http://dx.doi.org/10.1089/cmb.2021.0430.
[7] Ju, Fusong, Zhu, Jianwei, Zhang, Qi, Wei, Guozheng, Sun, Shiwei, Zheng, WeiMou, Bu, Dongbo. Seq-SetNet: directly exploiting multiple sequence alignment for protein secondary structure prediction. BIOINFORMATICS[J]. 2022, 38(4): 990-996, http://dx.doi.org/10.1093/bioinformatics/btab777.
[8] Huang, Chuncui, Tan, Zeshun, Zhao, Keli, Zou, Wenjun, Wang, Hui, Gao, Huanyu, Sun, Shiwei, Bu, Dongbo, Chai, Wengang, Li, Yan. The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor. ISCIENCE[J]. 2021, 24(11): http://dx.doi.org/10.1016/j.isci.2021.103272.
[9] Kong, Lupeng, Ju, Fusong, Zhang, Haicang, Sun, Shiwei, Bu, Dongbo. FALCON2: a web server for high-quality prediction of protein tertiary structures. BMC BIOINFORMATICS[J]. 2021, 22(1): http://dx.doi.org/10.1186/s12859-021-04353-8.
[10] Gu, Wenyan, Zhou, Aizhong, Wang, Lusheng, Sun, Shiwei, Cui, Xuefeng, Zhu, Daming. SVLR: Genome Structural Variant Detection Using Long-Read Sequencing Data. JOURNAL OF COMPUTATIONAL BIOLOGY[J]. 2021, 28(8): 774-788, http://dx.doi.org/10.1089/cmb.2021.0048.
[11] Wang, Hui, Wang, Yu, Hou, Meijie, Zhang, Chunming, Wang, Yaojun, Guo, Zhendong, Bu, Dongbo, Li, Yan, Huang, Chuncui, Sun, Shiwei. HepParser: An Intelligent Software Program for Deciphering Low-Molecular-Weight Heparin Based on Mass Spectrometry. FRONTIERS IN CHEMISTRY[J]. 2021, 9: http://dx.doi.org/10.3389/fchem.2021.723149.
[12] Huang, Chuncui, Sun, Shiwei, Yan, Jingyu, Wang, Hui, Zhou, Jinyu, Gao, Huanyu, Xie, Wenchun, Li, Yan, Chai, Wengang. Identification of carbohydrate peripheral epitopes important for recognition by positive-ion MALDI multistage mass spectrometry. CARBOHYDRATE POLYMERS[J]. 2020, 229: http://dx.doi.org/10.1016/j.carbpol.2019.115528.
[13] De Leoz, Maria Lorna A, Duewer, David L, Fung, Adam, Liu, Lily, Yau, Hoi Kei, Potter, Oscar, Staples, Gregory O, Furuki, Kenichiro, Frenkel, Ruth, Hu, Yunli, Sosic, Zoran, Zhang, Peiqing, Altmann, Friedrich, GrunwaldGrube, Clemens, Shao, Chun, Zaia, Joseph, Evers, Waltraud, Pengelley, Stuart, Suckau, Detlev, Wiechmann, Anja, Resemann, Anja, Jabs, Wolfgang, Beck, Alain, Froehlich, John W, Huang, Chuncui, Li, Yan, Liu, Yaming, Sun, Shiwei, Wang, Yaojun, Seo, Youngsuk, An, Hyun Joo, Reichardt, NielsChristian, Ruiz, Juan Echevarria, ArcherHartmann, Stephanie, Azadi, Parastoo, Bell, Len, Lakos, Zsuzsanna, An, Yanming, Cipollo, John F, PucicBakovic, Maja, Stambuk, Jerko, Lauc, Gordan, Li, Xu, Wang, Peng George, Bock, Andreas, Hennig, Rene, Rapp, Erdmann, Creskey, Marybeth, Cyr, Terry D, Nakano, Miyako, Sugiyama, Taiki, Leung, PuiKing Amy, LinkLenczowski, Pawe, Jaworek, Jolanta, Yang, Shuang, Zhang, Hui, Kelly, Tim, Klapoetke, Song, Cao, Rui, Kim, Jin Young, Lee, Hyun Kyoung, Lee, Ju Yeon, Yoo, Jong Shin, Kim, SaRang, Suh, SooKyung, de Haan, Noortje, Falck, David, LageveenKammeijer, Guinevere S M, Wuhrer, Manfred, Emery, Robert J, Kozak, Radoslaw P, Liew, Li Phing, Royle, Louise, Urbanowicz, Paulina A, Packer, Nicolle H, Song, Xiaomin, EverestDass, Arun, Lattova, Erika, Cajic, Samanta, Alagesan, Kathirvel, Kolarich, Daniel, Kasali, Toyin, Lindo, Viv, Chen, Yuetian, Goswami, Kudrat, Gau, Brian, Amunugama, Ravi, Jones, Richard, Stroop, Corn J M, Kato, Koichi, Yagi, Hirokazu, Kondo, Sachiko, Yuen, C T, Harazono, Akira, Shi, Xiaofeng, Magnelli, Paula E, Kasper, Brian T, Mahal, Lara, Harvey, David J, OFlaherty, Roisin, Rudd, Pauline M, Saldova, Radka, Hecht, Elizabeth S, Muddiman, David C, Kang, Jichao, Bhoskar, Prachi, Menard, Daniele, Saati, Andrew, Merle, Christine, Mast, Steven, Tep, Sam, Truong, Jennie, Nishikaze, Takashi, Sekiya, Sadanori, Shafer, Aaron, Funaoka, Sohei, Toyoda, Masaaki, de Vreugd, Peter, Caron, Cassie, Pradhan, Pralima, Tan, Niclas Chiang, Mechref, Yehia, Patil, Sachin, Rohrer, Jeffrey S, Chakrabarti, Ranjan, Dadke, Disha, Lahori, Mohammedazam, Zou, Chunxia, Cairo, Christopher, Reiz, Bela, Whittal, Randy M, Lebrilla, Carlito B, Wu, Lauren, Guttman, Andras, Szigeti, Marton, Kremkow, Benjamin G, Lee, Kelvin H, Sihlbom, Carina, Adamczyk, Barbara, Jin, Chunsheng, Karlsson, Niclas G, Ornros, Jessica, Larson, Gran, Nilsson, Jonas, Meyer, Bernd, Wiegandt, Alena, Komatsu, Emy, Perreault, Helene, Bodnar, Edward D, Said, Nassur, Francois, YannisNicolas, LeizeWagner, Emmanuelle, Maier, Sandra, Zeck, Anne, Heck, Albert J R, Yang, Yang, Haselberg, Rob, Yu, Ying Qing, Alley, William, Leone, Joseph W, Yuan, Hua, Stein, Stephen E. NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. MOLECULAR & CELLULAR PROTEOMICS[J]. 2020, 19(1): 11-30, http://dx.doi.org/10.1074/mcp.RA119.001677.
[14] Wang, Hui, Zhang, Jingwei, Dong, Junchuan, Hou, Meijie, Pan, Weiyi, Bu, Dongbo, Zhou, Jinyu, Zhang, Qi, Wang, Yaojun, Zhao, Keli, Li, Yan, Huang, Chuncui, Sun, Shiwei. Identification of glycan branching patterns using multistage mass spectrometry with spectra tree analysis. JOURNAL OF PROTEOMICS[J]. 2020, 217: http://dx.doi.org/10.1016/j.jprot.2020.103649.
[15] Hou, Meijie, Wang, Yu, Wang, Hui, Wang, Yaojun, Zhao, Keli, Li, Yan, Bu, Dongbo, Huang, Chuncui, Sun, Shiwei. Toward automated identification of glycan mixtures using multistage mass spectrometry. GLYCOBIOLOGY[J]. 2020, 30(12): 1061-1061, https://www.webofscience.com/wos/woscc/full-record/WOS:000606577100089.
[16] Zhang, Qi, Zhu, Jianwei, Ju, Fusong, Kong, Lupeng, Sun, Shiwei, Zheng, WeiMou, Bu, Dongbo. ISSEC: inferring contacts among protein secondary structure elements using deep object detection. BMC BIOINFORMATICS[J]. 2020, 21(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643357/.
[17] Huang, Chuncui, Wang, Hui, Bu, Dongbo, Zhou, Jinyu, Dong, Junchuan, Zhang, Jingwei, Gao, Huanyu, Wang, Yaojun, Chai, Wengang, Sun, Shiwei, Li, Yan. Multistage mass spectrometry with intelligent precursor selection for N-glycan branching pattern analysis. CARBOHYDRATE POLYMERS[J]. 2020, 237: http://dx.doi.org/10.1016/j.carbpol.2020.116122.
[18] Liu, Hong, Han, Maozhen, Li, Shuai Cheng, Tan, Guangming, Sun, Shiwei, Hu, Zhiqiang, Yang, Pengshuo, Wang, Rui, Liu, Yawen, Chen, Feng, Peng, Jianjun, Peng, Hong, Song, Hongxing, Xia, Yang, Chu, Liqun, Zhou, Quan, Guan, Feng, Wu, Jing, Bu, Dongbo, Ning, Kang. Resilience of human gut microbial communities for the long stay with multiple dietary shifts. GUT. 2019, 68(12): 2254-+, [19] Zhang, Haicang, Zhang, Qi, Ju, Fusong, Zhu, Jianwei, Gao, Yujuan, Xie, Ziwei, Deng, Minghua, Sun, Shiwei, Zheng, WeiMou, Bu, Dongbo. Predicting protein inter-residue contacts using composite likelihood maximization and deep learning. BMC BIOINFORMATICS[J]. 2019, 20(1): http://dx.doi.org/10.1186/s12859-019-3051-7.
[20] Zhang, Haicang, Zhang, Qi, Ju, Fusong, Zhu, Jianwei, Gao, Yujuan, Xie, Ziwei, Deng, Minghua, Sun, Shiwei, Zheng, WeiMou, Bu, Dongbo. Predicting protein inter-residue contacts using composite likelihood maximization and deep learning (vol 20, 537, 2019). BMC BIOINFORMATICS. 2019, 20(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000499975200001.
[21] Ju Fusong, Zhu Jianwei, Wei Guozheng, Zhang Qi, Sun Shiwei, Bu Dongbo. Seq-SetNet: Exploring Sequence Sets for Inferring Structures. 2019, http://arxiv.org/abs/1906.11196.
[22] Wang, Yaojun, Bu, Dongbo, Huang, Chuncui, Wang, Hui, Zhou, Jinyu, Dong, Junchuan, Pan, Weiyi, Zhang, Jingwei, Zhang, Qi, Li, Yan, Sun, Shiwei. Best-first search guided multistage mass spectrometry-based glycan identification. BIOINFORMATICS[J]. 2019, 35(17): 2991-2997, https://www.webofscience.com/wos/woscc/full-record/WOS:000487323400014.
[23] Ju, Fusong, Zhang, Jingwei, Bu, Dongbo, Li, Yan, Zhou, Jinyu, Wang, Hui, Wang, Yaojun, Huang, Chuncui, Sun, Shiwei. De novo glycan structural identification from mass spectra using tree merging strategy. COMPUTATIONAL BIOLOGY AND CHEMISTRY[J]. 2019, 80: 217-224, http://dx.doi.org/10.1016/j.compbiolchem.2019.03.015.
[24] Chao Wang, Yi Wei, Haicang Zhang, Lupeng Kong, Shiwei Sun, WeiMou Zheng, Dongbo Bu. Constructing effective energy functions for protein structure prediction through broadening attraction-basin and reverse Monte Carlo sampling. BMC BIOINFORMATICS[J]. 2019, 20(S3): 99-108, https://doaj.org/article/6ed28e082ad847f19e2703f86cd71abd.
[25] Sun, Shiwei, Huang, Chuncui, Wang, Yaojun, Liu, Yaming, Zhang, Jingwei, Zhou, Jinyu, Gao, Feng, Yang, Fei, Chen, Runsheng, Mulloy, Barbara, Chai, Wengang, Li, Yan, Bu, Dongbo. Toward Automated Identification of Glycan Branching Patterns Using Multistage Mass Spectrometry with Intelligent Precursor Selection. ANALYTICAL CHEMISTRY[J]. 2018, 90(24): 14412-14422, https://www.webofscience.com/wos/woscc/full-record/WOS:000454182800044.
[26] Wang, Yaojun, Zhang, Jingwei, Bu, Dongbo, Sun, Shiwei. TagDict: Prediction of Theoretical Spectra of Peptides Based on A Tag Dictionary. CURRENT BIOINFORMATICS[J]. 2018, 13(5): 444-449, https://www.webofscience.com/wos/woscc/full-record/WOS:000440847000003.
[27] Wang YaoJun, Huang ChunCui, Gao Feng, Zhang JingWei, Li Yan, Bu DongBo, Sun ShiWei. Survey on Algorithms for Tandem Mass Spectrometry Oligosaccharide Identification. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2017, 44(10): 830-847, https://www.webofscience.com/wos/woscc/full-record/WOS:000413991500003.
[28] Zhu, Jianwei, Zhang, Haicang, Li, Shuai Cheng, Wang, Chao, Kong, Lupeng, Sun, Shiwei, Zheng, WeiMou, Bu, Dongbo. Improving protein fold recognition by extracting fold-specific features from predicted residue-residue contacts. BIOINFORMATICS[J]. 2017, 33(23): 3749-3757, http://dx.doi.org/10.1093/bioinformatics/btx514.
[29] Gong, Haie, Zhang, Haicang, Zhu, Jianwei, Wang, Chao, Sun, Shiwei, Zheng, WeiMou, Bu, Dongbo. Improving prediction of burial state of residues by exploiting correlation among residues. BMC BIOINFORMATICS[J]. 2017, 18(Suppl 3): http://dx.doi.org/10.1186/s12859-017-1475-5.
[30] Sun, Shiwei, Huang, Chuncui, Zhang, Jingwei, Wang, Yaojun, Bu, Dongbo, Li, Yan, Chai, Wengang. gID: A new strategy for identification of glycan branching patterns using multistage mass spectrometry. GLYCOBIOLOGYnull. 2017, 27(12): 1212-1212, https://www.webofscience.com/wos/woscc/full-record/WOS:000423267000107.
[31] Wang YaoJun, Huang ChunCui, Gao Feng, Zhang JingWei, Li Yan, Bu DongBo, Sun ShiWei. Survey on Algorithms for Tandem Mass Spectrometry Oligosaccharide Identification. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2017, 44(10): 830-847, https://www.webofscience.com/wos/woscc/full-record/WOS:000413991500003.
[32] Huang, Chunlin, Liu, Xingwu, Sun, Shiwei, Li, Shuai Cheng, Deng, Minghua, He, Guangxue, Zhang, Haicang, Wang, Chao, Zhou, Yang, Zhao, Yanlin, Bu, Dongbo. Insights into the transmission of respiratory infectious diseases through empirical human contact networks. SCIENTIFIC REPORTS[J]. 2016, 6: http://ir.itp.ac.cn/handle/311006/23184.
[33] Wang, Chao, Zhang, Haicang, Zheng, WeiMou, Xu, Dong, Zhu, Jianwei, Wang, Bing, Ning, Kang, Sun, Shiwei, Li, Shuai Cheng, Bu, Dongbo. FALCON@home: a high-throughput protein structure prediction server based on remote homologue recognition. BIOINFORMATICS[J]. 2016, 32(3): 462-464, http://ir.itp.ac.cn/handle/311006/23139.
[34] Sun, Shiwei, Huang, Chuncui, Wang, Yaojun, Liu, Naming, Chai, Wengang, Yang, Fei, Zhang, Jingwei, Gao, Feng, Chen, Runsheng, Li, Yan, Bu, Dongbo. Towards automated identification of glycan branching patterns using multistage mass spectrometry with intelligent precursor selection. GLYCOBIOLOGYnull. 2016, 26(12): 1458-1458, https://www.webofscience.com/wos/woscc/full-record/WOS:000392935600208.
[35] 孙世伟. Preprocess and condensation of Raman spectrum for single-cell phenotype analysis. GIW2015. 2015, [36] Sun, Shiwei, Wang, Xuetao, Gao, Xin, Ren, Lihui, Su, Xiaoquan, Bu, Dongbo, Ning, Kang. Condensing Raman spectrum for single-cell phenotype analysis. BMC BIOINFORMATICS[J]. 2015, 16(Suppl 18): S15-S15, http://ir.qibebt.ac.cn/handle/337004/7915.
[37] Wang, Yaojun, Yang, Fei, Wu, Peng, Bu, Dongbo, Sun, Shiwei. OpenMS-Simulator: an open-source software for theoretical tandem mass spectrum prediction. BMC BIOINFORMATICS[J]. 2015, 16(1): http://www.corc.org.cn/handle/1471x/2374290.
[38] 杨福愉. MS-Simulator: Predicting Y-Ion Intensities for Peptides with Two Charges Based on the Intensity Ratio of Neighboring Ions. JOURNAL OF PROTEOME RESEARCH[J]. 2012, 11(9): 4509-4516, http://www.irgrid.ac.cn/handle/1471x/756860.
[39] 王耀君, 孙世伟, 卜东波, 刘金刚. 串联质谱谱库搜索鉴定技术综述. 计算机工程[J]. 2012, 38(7): 269-272, http://lib.cqvip.com/Qikan/Article/Detail?id=41609907.
[40] 王耀君, 孙世伟, 卜东波, 刘金刚. 基于特征比对算法的蛋白质质谱鉴定仿真. 计算机仿真[J]. 2012, 29(10): 392-395, http://lib.cqvip.com/Qikan/Article/Detail?id=43536986.
[41] Shiwei Sun, Dongbo Bu, Hong Zhang, Yantao Qiao. PI: An open-source software package for validation of the SEQUEST result and visualization of mass spectrum. 2011, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201706284142632ZK.
[42] Qiao, Yantao, Zhang, Hong, Bu, Dongbo, Sun, Shiwei. PI: An open-source software package for validation of the SEQUEST result and visualization of mass spectrum. BMC BIOINFORMATICS[J]. 2011, 12(1): 234-234, http://dx.doi.org/10.1186/1471-2105-12-234.
[43] Zhang, Shenghui, Wang, Yaojun, Bu, Dongbo, Zhang, Hong, Sun, Shiwei. ProbPS: A new model for peak selection based on quantifying the dependence of the existence of derivative peaks on primary ion intensity. BMC BIOINFORMATICS[J]. 2011, 12(1): 346-346, http://dx.doi.org/10.1186/1471-2105-12-346.
[44] 乔彦涛, 缪佳铮, 孙世伟, 刘金刚, 卜东波. 串联质谱的蛋白质序列鉴定技术综述. 计算机科学与探索[J]. 2010, 97-107, http://lib.cqvip.com/Qikan/Article/Detail?id=32968831.
[45] Sun, Shiwei, Yu, Chungong, Qiao, Yantao, Lin, Yu, Dong, Gongjin, Liu, Changning, Zhang, Lingfen, Zhang, Zhuo, Cai, Jinjin, Zhang, Hong, Bu, Dongbo. Deriving the probabilities of water loss and ammonia loss for amino acids from tandem mass spectra. JOURNAL OF PROTEOME RESEARCH[J]. 2008, 7(1): 202-208, http://www.irgrid.ac.cn/handle/1471x/757736.
[46] Shao, Yi, Sun, Zhenyuan, Sun, Shiwei, Zhao, Yi, Sin, Wan Yee, Yuan, Yanhua, Simpson, Andrew J, Old, Lloyd J, Sang, Xinting, Mao, Yilei, Xie, Yong, Huang, Jiefu, Zhao, Haitao. Identification and expression analysis of novel LAGE-1 alleles with single nucleotide polymorphisms in cancer patients. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY[J]. 2008, 134(4): 495-502, https://www.webofscience.com/wos/woscc/full-record/WOS:000253572000009.
[47] 陈润生. MicroRNA regulation of messenger-like noncoding RNAs: a network of mutual microRNA control. TRENDS IN GENETICS[J]. 2008, 24(72): 323-327, http://dx.doi.org/10.1016/j.tig.2008.04.004.
[48] 孙世伟. 蛋白质质谱分析中的算法问题研究. 2007, [49] 陈润生. Faster and more accurate global protein function assignment from protein interaction networks using the MFGO algorithm. FEBS LETTERS[J]. 2006, 580(103): 1891-1896, http://dx.doi.org/10.1016/j.febslet.2006.02.053.
[50] 陈润生. A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data. BMC BIOINFORMATICS[J]. 2006, 7(100): 222-222, https://doaj.org/article/6758bc738b414caea1e0a0546da7adc0.
[51] 陈润生. 基于全基因组比较的SARS冠状病毒种系进化分析. 科学通报[J]. 2003, 48(12): 1242-1245, http://lib.cqvip.com/Qikan/Article/Detail?id=9070004.0.
[52] 唐祥海, 温新, 孙世伟, 蒋海燕, 陈铁红. 高钛含量钛硅中孔材料的合成及理化性质研究. 高等学校化学学报[J]. 2001, 200-203, http://lib.cqvip.com/Qikan/Article/Detail?id=1001109850.
[53] Tang XiangHai, Wen Xin, Sun ShiWei, Jiang HaiYan, Chen TieHong. Studies on the Synthesis and Physicochemical Property of Mesoporous Titanosilicate with High Titanium Content. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE[J]. 2001, 22: 200-203, https://www.webofscience.com/wos/woscc/full-record/WOS:000209777300047.
[54] Fusong Ju, Jingwei Zhang, Dongbo Bu, Yan Li, Jinyu Zhou, Hui Wang, Yaojun Wang, Chuncui Huang, Shiwei Sun. De ovo glycan structural identification from mass spectra using tree merging strategy. COMPUTATIONAL BIOLOGY AND CHEMISTRY. http://dx.doi.org/10.1016/j.compbiolchem.2019.03.015.

   

（ 1 ） 磷酸化肽质谱鉴定中的算法问题研究, 主持, 国家级, 2009-01--2011-12
（ 2 ） 基于质谱词典思想的谱库设计及理论谱预测研究, 主持, 国家级, 2013-01--2016-12
（ 3 ） 基于高性能计算及重核技术的蛋白质质谱比对服务器建设, 主持, 省级, 2010-01--2012-12
（ 4 ） 基于质谱技术高通量的完整信息糖蛋白/糖肽的鉴定新方法研究, 主持, 国家级, 2017-01--2020-12
（ 5 ） 基于多级质谱的高通量鉴定糖 链精细结构方法的建立及其应用研究, 主持, 国家级, 2017-01--2019-12
（ 6 ） 高分辨质谱肝素化合物结构解析, 主持, 省级, 2019-07--2020-06
（ 7 ） 基于多级质谱技术的糖结构鉴定算法研究和软件开发, 参与, 市地级, 2019-01--2019-12
（ 8 ） 高通量的完整信息的糖链序列鉴定算法研究及平台实现, 主持, 国家级, 2021-01--2024-12

（1）De Novo glycan structural identification from mass spectra using tree merging strategy   2019-02-14
（2）Condensing Raman Spectrum for Single-cell Phenotype Analysis   Shiwei Sun, Xuetao Wang, Xin Gao4, Lihui Ren, Xiaoquan Su, Dongbo Bu and Kang Ning   2015-09-09
（3）IPS: 一种基于多级质谱进行寡糖预测的新算法   2015年中国酶工程与糖生物工程学术研讨会   Shiwei Sun, Yaojun Wang, Chuncui Huang, Runsheng, Chen, Yan Li and Dongbo Bu.   2015-08-20
（4）Predicting y ion intensities for peptides with two charges based on the intensity ratio of neighboring ions.   Shiwei Sun, Yaojun Wang, Bin Ma and Dongbo Bu.   2012-03-10

已指导学生

高枫  硕士研究生  085211-计算机技术  

张敬玮  硕士研究生  081202-计算机软件与理论  

张琪  硕士研究生  081203-计算机应用技术  

候梅洁  硕士研究生  085211-计算机技术  

潘唯一  硕士研究生  085211-计算机技术  

董俊川  硕士研究生  085211-计算机技术  

现指导学生

王宇  硕士研究生  081203-计算机应用技术  

刘世伟  硕士研究生  081203-计算机应用技术