宓现强,中国科学院上海微系统与信息技术研究所研究员,博士生导师,课题组长,超导电子学卓越创新中心生物交叉方向负责人。国家重点研发计划项目首席科学家, 上海市优秀学术带头人。
电子邮件:mixq@mail.sim.ac.cn
通信地址:上海市浦东新区张江高科技园区海科路100号
邮政编码:201203
研究领域
生命系统网络分析、纳米生物编码探针,微流控生物检测及器官芯片,液滴软物质,量子探测及成像
招生信息
招生专业
招生方向
教育
学历
学位
工作经历
专利与奖励
发表论文情况
近5年部分代表性论文:
2022年
1 Chenwei Xiong, Jie Li, Luyao Li, Long Chen, Rong Zhang Xianqiang Mi*,Yifan Liu.Label-free electrical monitoring of nucleic acid amplification with integrated hydrogel ionic diodes. Materials Today Bio,15 (2022) 100281
2 Shuainan Li, Chenguang Wang, Yi Xu, Wei Wang, Xiaoshuang Zhao, Qiuling Qian and Xianqiang Mi*. A designer DNA tetrahedron-based molecular beacon for tumor-related microRNA fluorescence imaging in living cells.Analyst, 2022, 147, 2231 - 2237
3 Qiuling Qian,Guifang He,Chenguang Wang,Shuainan Li,Xiaoshuang Zhao,Yi Xu,Xianqiang Mi*.Poly‐adenine‐mediated spherical nucleic acid probes for live cell fluorescence imaging of tumor‐related microRNAs.Molecular Biology Reports (2022) 49:3705–3712
4 Dongsheng Mao, Mengmeng Zheng, Wenxing Li, Yi Xu, Chengguang Wang, Qiuling Qian, Shuainan Li, Guifang Chen, Xiaoli Zhu, Xianqiang Mi*. Cubic DNA nanocage-based three-dimensional molecular beacon for accurate detection of exosomal miRNAs in confined spaces. Biosensors and Bioelectronics. 2022, 204:114077
5 Chenguang Wang ,Wei Wang ,Yi Xu, Xiaoshuang Zhao, Shuainan Li, Qiuling Qian and Xianqiang Mi*. Tetrahedral DNA Framework-Programmed Electrochemical Biosenors with Gold Nanoparticles for Ultrasensitive Cell-Free DNA Detection.Nanomaterials 2022, 12, 666. https://doi.org/10.3390/nano12040666
6Rong Tao; Shulin Zhang; Yuexia Wang; Xianqiang Mi; Jian Ma; Chengxing Shen; Guoyan Zheng.MCG-Net: End-to-end Fine-grained Delineation and Diagnostic Classification of Cardiac Events from Magnetocardiographs,IEEE J. Biomed. Health Informatics 26(3): 1057-1067 (2022)
2021
1 Chenguang Wang,Yi Xu, Xiaoshuang Zhao, Shuainai Li, Qiuling Qian, Wei Wang and Xianqiang Mi*.A double-tetrahedral DNA framework based electrochemical biosensor for ultrasensitive detection and release of circulating tumor cells. Analyst. 2021,146(21):6474-6481,DOI: 10.1039/d1an01470f
2DNA tetrahedron mediated immune sandwich assay for rapid, sensitive, and automatic detection of PSA through microfluidic electrochemical detection system.Nature microsystems and nanoengineering, 2021;7:33
3Yi Zhang, Wei Jiang, Dezhi Feng, Chenguang Wang, Yi Xu , Yufeng Shan, Jianlu Wang , Ziwei Yin, Huiyong Deng,*, Xianqiang Mi,* and Ning Dai,* Bio-Separated and Gate-Free 2D MoS2 Biosensor Array for Ultrasensitive Detection of BRCA1. Nanomaterials 2021, 11, 545. https://doi.org/10.3390/nano11020545
4Yi Zhang, Dezhi Feng, Yi Xu, Ziwei Yin, Wei Dou, UM E Habiba, Changyi Pan, Zongkun Zhang, Hao Mou, Huiyong Deng,*, Xianqiang Mi,*, Ning Dai.DNA-based functionalization of two-dimensional MoS2 FET biosensor for ultrasensitive detection of PSA .Applied Surface Science. 548 (2021) 149169
2020及之前
1 A DNA Tetrahedral Structure-Mediated Ultrasensitive Fluorescent Microarray Platform for Nucleic Acids Tests.Sensors and Actuator B : Chemical.2020,321: 128538
2 Dezhi Feng,Jing Su,Guifang He, Yi Xu,Chenguang Wang,Mengmeng Zheng,Qiuling Qian,XianQiang Mi. Electrochemical DNA Sensor for Sensitive brca1 Detection Based on DNA Tetrahedral-Structured Probe and Poly-Adenine Mediated Gold Nanoparticles.Biosensors 2020, 10, 78; doi:10.3390/bios10070078
1 Framework Nucleic Acid-Enabled Programming of Electrochemical Catalytic Properties of Artificial Enzymes. ACS Appl. Mater.Interfaces.2019,11(24):21859-21864
2 Au NFs flower modified disposable 16-SPCE electrochemical biosensor for label-free and multiplex detection of Glycated hemoglobin.Tanlanta. 2019,201,119-125
3 Poly-adenine-mediated Spherical Nucleic Acids for Strand Displacement-based DNA/RNA Detection.Biosensors and Bioelectronics. 2019,127:85–91
4Microfluidic cap-to-dispense (μCD): a universal microfluidic–robotic interface for automated pipette-free high-precision liquid handling. Lab on Chip,2019,19,3405–3415
1 Fluorescent biosensors enabled by graphene and graphene oxide.Biosensors and Bioelectronics. 2017;89(Pt 1):96-106. (ESI 1%高被引论文)
2 Universal fluorescence biosensor platform based on graphene quantum dots and pyrene-functionalized molecular beacons for detection of microRNAs.ACS Appl Mater&Interfaces. 2015;7(30):16152-6
3 Elaborately designed diblock nanoprobes for simultaneous multicolor detection of microRNAs.Nanoscale,2015,7(38):15822-15829(年度“hot paper”)
4 DNA Tetrahedral Nanostructure-Based Electrochemical miRNA Biosensor for Simultaneous Detection of Multiple miRNAs in Pancreatic Carcinoma. ACS Appl Mater Interfaces.2017, 9(28):24118-2412
5 A novel ultrasensitive electrochemical DNA sensor based on double DNA tetrahedral nanostructures. Biosensors and Bioelectronics 2015,71:434-438
6 An electrochemical immunosensor for quantitative detection of ficolin-3.Nanotechnology.2016;27(25):254003. doi: 10.1088/0957-4484/27/25/254003
7 DNA nanotechnology mediated gold nanoparticle conjugates and their applications in biomedicine. Chinese Journal of Chemistry. 2016,34(3):299–307