发表论文
[1] Wang, Qinying, Dong, Xiaoxu, Hu, Tingting, Qu, Chao, Lu, Jing, Zhou, Yue, Li, Jinsong, Pei, Gang. Constitutive Activity of Serotonin Receptor 6 Regulates Human Cerebral Organoids Formation and Depression-like Behaviors. STEM CELL REPORTS[J]. 2021, 16(1): 75-88, http://dx.doi.org/10.1016/j.stemcr.2020.11.015.[2] Yi Li, Jing Lu, Xin Cao, Hongwei Zhao, Longfei Gao, Peng Xia, Gang Pei. A Newly Synthesized Rhamnoside Derivative Alleviates Alzheimer’s Amyloid-β-Induced Oxidative Stress, Mitochondrial Dysfunction, and Cell Senescence through Upregulating SIRT3. Oxidative Medicine and Cellular Longevity[J]. 2020, 2020: https://doaj.org/article/f905aed91a0c4e0db5a7dbf321f4d101.[3] Zhou, Yue, Duan, Yanhong, Huang, Shichao, Zhou, Xuan, Zhou, Lishuang, Hu, Tingting, Yang, Yongfeng, Lu, Jing, Ding, Kan, Guo, Dean, Cao, Xiaohua, Pei, Gang. Polysaccharides from Lycium barbarum ameliorate amyloid pathology and cognitive functions in APP/PS1 transgenic mice. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 144: 1004-1012, http://dx.doi.org/10.1016/j.ijbiomac.2019.09.177.[4] Pei Gang. Correction for: A novel rhamnoside derivative PL402 up-regulates matrix metalloproteinase 3/9 to promote Aβ degradation and alleviates Alzheimer’s-like pathology. Aging. 2020, [5] Wang, Qinying, Dong, Xiaoxu, Lu, Jing, Hu, Tingting, Pei, Gang. Constitutive activity of a G protein-coupled receptor, DRD1, contributes to human cerebral organoid formation. STEM CELLS[J]. 2020, 38(5): 653-665, https://www.webofscience.com/wos/woscc/full-record/WOS:000513997300001.[6] An, Yuqian, Zhang, Hong, Huang, Shichao, Pei, Gang. PL201, a Reported Rhamnoside Against Alzheimer's Disease Pathology, Alleviates Neuroinflammation and Stimulates Nrf2 Signaling. FRONTIERS IN IMMUNOLOGY[J]. 2020, 11: https://doaj.org/article/cf14383ebb234478bc1ea395e2d3fb96.[7] Gao, Longfei, Zhang, Zhen, Lu, Jing, Pei, Gang. Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer. FRONTIERS IN CELLULAR NEUROSCIENCE[J]. 2019, 13: https://doaj.org/article/30d0ea6ce48d4a5783af38421ec91d5a.[8] Pei Gang. An analog derived from phenylpropanoids ameliorates Alzheimer’s diseaseelike pathology and protects mitochondrial function. Neurobiology of Aging. 2019, [9] Gao, Longfei, Huang, Shichao, Zhang, Hong, Hua, Wei, Xin, Shunmei, Cheng, Lin, Guan, Wuqiang, Yu, Yongchun, Mao, Ying, Pei, Gang. Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells. SCIENTIFIC REPORTS[J]. 2019, 9(1): http://dx.doi.org/10.1038/s41598-019-39852-5.[10] Xin Wang, Gang Pei. Visualization of Alzheimer’s Disease Related α-/β-/γ-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer. Frontiers in Molecular Neuroscience[J]. 2018, 11: https://doaj.org/article/62596de022a544af8494577e14345c68.[11] Wang Xin, Wang Congcong, Pei Gang. α-secretase ADAM10 physically interacts with β-secretase BACE1 in neurons and regulates CHL1 proteolysis. Journal of Molecular Cell Biology[J]. 2018, 10(5): 411-422, [12] Yang, Wenjuan, Zhou, Keyan, Zhou, Yue, An, Yuqian, Hu, Tingting, Lu, Jing, Huang, Shichao, Pei, Gang. Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice. FRONTIERS IN AGING NEUROSCIENCE[J]. 2018, 10: http://202.127.25.143/handle/331003/3445.[13] Pei Gang. NF-kB directly regulates b-arrestin-1 expression and forms a negative feedback circuit in TNF-a–induced cell death. The FASEB Journal. 2018, [14] Jing Lu, Xiaohang Li, Qinying Wang, Gang Pei. Dopamine D2 receptor and β-arrestin 2 mediate Amyloid-β elevation induced by anti-parkinson's disease drugs, levodopa and piribedil, in neuronal cells.. PLoS ONE[J]. 2017, 12(3): https://doaj.org/article/f3911f37ff0f4a848d47f658b9e6b0ab.[15] Huang, Shichao, Mao, Jianxin, Ding, Kan, Zhou, Yue, Zeng, Xianglu, Yang, Wenjuan, Wang, Peipei, Zhao, Cun, Yao, Jian, Xia, Peng, Pei, Gang. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease. STEM CELL REPORTS[J]. 2017, 8(1): 84-94, http://dx.doi.org/10.1016/j.stemcr.2016.12.007.[16] Gao, Longfei, Guan, Wuqiang, Wang, Min, Wang, Huihan, Yu, Jiali, Liu, Qing, Qiu, Binlong, Yu, Yongchun, Ping, Yifang, Bian, Xiuwu, Shen, Li, Pei, Gang. Direct Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules. STEM CELL REPORTS[J]. 2017, 8(3): 538-547, http://dx.doi.org/10.1016/j.stemcr.2017.01.014.[17] Cai, Qing, Li, Yuanyuan, Pei, Gang. Polysaccharides from Ganoderma lucidum attenuate microglia-mediated neuroinflammation and modulate microglial phagocytosis and behavioural response. JOURNAL OF NEUROINFLAMMATION[J]. 2017, 14(1): http://dx.doi.org/10.1186/s12974-017-0839-0.[18] Guo, Ao, Huang, Shichao, Yu, Jiali, Wang, Huihan, Li, Haisen, Pei, Gang, Shen, Li. Single-Cell Dynamic Analysis of Mitosis in Haploid Embryonic Stem Cells Shows the Prolonged Metaphase and Its Association with Self-diploidization. STEM CELL REPORTS[J]. 2017, 8(5): 1124-1134, http://dx.doi.org/10.1016/j.stemcr.2017.03.025.[19] Xiaohang Li, Qinying Wang, Tingting Hu, Ying Wang, Jian Zhao, Jing Lu, Gang Pei. A tricyclic antidepressant, amoxapine, reduces amyloid-β generation through multiple serotonin receptor 6-mediated targets. Scientific Reports[J]. 2017, 7(1): 1-10, https://doaj.org/article/ced7e5c09b5a420c95dbac43908490dd.[20] Congcong Wang, Xianglu Zeng, Zhaocai Zhou, Jian Zhao, Gang Pei. β-arrestin-1 contributes to brown fat function and directly interacts with PPARα and PPARγ. Scientific Reports. 2016, 6: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908412/.[21] Xiaohang Li, Jin Cui, Yang Yu, Wei Li, Yujun Hou, Xin Wang, Dapeng Qin, Cun Zhao, Xinsheng Yao, Jian Zhao, Gang Pei. Traditional Chinese Nootropic Medicine Radix Polygalae and Its Active Constituent Onjisaponin B Reduce β-Amyloid Production and Improve Cognitive Impairments.. PLoS ONE[J]. 2016, 11(3): https://doaj.org/article/9f58d7c4a527488080f9447dac9ed2a7.[22] Jing Lu, Jin Cui, Xiaohang Li, Xin Wang, Yue Zhou, Wenjuan Yang, Ming Chen, Jian Zhao, Gang Pei. An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity.. PLoS ONE[J]. 2016, 11(11): https://doaj.org/article/48132f9baa3f4822b81c1fba09bb0da0.[23] Qing Cai, Yuanyuan Li, Jianxin Mao, Gang Pei. Neurogenesis-Promoting Natural Product α-Asarone Modulates Morphological Dynamics of Activated Microglia. Frontiers in Cellular Neuroscience. 2016, 10: [24] Hu, Wenxiang, Qiu, Binlong, Guan, Wuqiang, Wang, Qinying, Wang, Min, Li, Wei, Gao, Longfei, Shen, Lu, Huang, Yin, Xie, Gangcai, Zhao, Hanzhi, Jin, Ying, Tang, Beisha, Yu, Yongchun, Zhao, Jian, Pei, Gang. Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules. CELL STEM CELL[J]. 2015, 17(2): 204-212, http://dx.doi.org/10.1016/j.stem.2015.07.006.[25] Cheng, Lin, Gao, Longfei, Guan, Wuqiang, Mao, Jianxin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Pei, Gang. Direct conversion of astrocytes into neuronal cells by drug cocktail. CELL RESEARCHnull. 2015, 25(11): 1269-1272, https://www.webofscience.com/wos/woscc/full-record/WOS:000365049100012.[26] Pei Gang. γ- Secretase modulators and inhibitors induce different conformational changes of presenilin 1 revealed by FLIM and FRET.. J Alzheimers Dis. 2015, [27] Mao, Jianxin, Huang, Shichao, Liu, Shangfeng, Feng, XiaoLin, Yu, Miao, Liu, Junjun, Sun, Yi Eve, Chen, Guoliang, Yu, Yang, Zhao, Jian, Pei, Gang. A herbal medicine for Alzheimer's disease and its active constituents promote neural progenitor proliferation. AGING CELL[J]. 2015, 14(5): 784-796, https://www.webofscience.com/wos/woscc/full-record/WOS:000360767200008.[28] 裴钢. Generation of Neural Progenitor Cells by Chemical Cocktails and Hypoxia. Cell Res. 2014, 24(6): 665-679, [29] Hou, Yujun, Wang, Ying, Zhao, Jian, Li, Xiaohang, Cui, Jin, Ding, Jianqing, Wang, Ying, Zeng, Xianglu, Ling, Yun, Shen, Xiaoheng, Chen, Shengdi, Huang, Chenggang, Pei, Gang. Smart Soup, a Traditional Chinese Medicine Formula, Ameliorates Amyloid Pathology and Related Cognitive Deficits. PLOS ONE[J]. 2014, 9(11): https://www.webofscience.com/wos/woscc/full-record/WOS:000345250400015.[30] 裴钢. Beta-arrestin1 regulates γ-secretase complex assembly and modulates amyloid-β pathology. Cell Res. 2013, 23(3): 351-365, [31] Pei Gang. Deficiency of b-arrestin1 ameliorates collagen-induced arthritis with impaired TH17 cell differentiation.. PNAS. 2013, [32] Hu, Wenxiang, Zhao, Jian, Pei, Gang. Activation of Aryl Hydrocarbon Receptor (AhR) by Tranilast, an Anti-allergy Drug, Promotes miR-302 Expression and Cell Reprogramming. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2013, 288(32): 22972-22984, http://dx.doi.org/10.1074/jbc.M113.475624.[33] Yue, Rui, Li, Haisen, Liu, Huan, Li, Yuanyuan, Wei, Bin, Gao, Ge, Jin, Yi, Liu, Tingxi, Wei, Liping, Du, Jiulin, Pei, Gang. Thrombin Receptor Regulates Hematopoiesis and Endothelial-to-Hematopoietic Transition. DEVELOPMENTAL CELL[J]. 2012, 22(5): 1092-1100, http://dx.doi.org/10.1016/j.devcel.2012.01.025.[34] 裴钢. {beta}arrestin1 represses adipogenesis and inflammatary responses through its interaction with PPAR{gamma}. J Biol Chem. 2011, 286: 28403-28413, [35] Pei Gang. βarrestin1 represses diet-induced obesity. J Biol Chem. 2011, [36] Chen, Taotao, Shen, Li, Yu, Jie, Wan, Hongjiang, Guo, Ao, Chen, Jiekai, Long, Yuan, Zhao, Jian, Pei, Gang. Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells. AGING CELL[J]. 2011, 10(5): 908-911, https://www.webofscience.com/wos/woscc/full-record/WOS:000294864400017.[37] Shen, Li, Gao, Ge, Zhang, Ying, Zhang, He, Ye, Zhiqiang, Huang, Shichao, Huang, Jinyan, Kang, Jiuhong. A single amino acid substitution confers enhanced methylation activity of mammalian Dnmt3b on chromatin DNA. NUCLEIC ACIDS RESEARCH[J]. 2010, 38(18): 6054-6064, [38] 裴钢. E-cadherin-Mediated Cell-Cell Contact is Critical for Induced Pluripotent Stem Cell Generation. Stem Cells[J]. 2010, 28(8): 1315-1325, [39] Teng, Lin, Zhao, Jian, Wang, Feifei, Ma, Lan, Pei, Gang. A GPCR/secretase complex regulates beta- and gamma-secretase specificity for A beta production and contributes to AD pathogenesis. CELL RESEARCH[J]. 2010, 20(2): 138-153, [40] 裴钢. β-Arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression. Cell. 2009, 139(3): 535-546, http://dx.doi.org/10.1016/j.cell.2009.08.038.[41] 裴钢. MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol. 2009, 10: 1252 –1259-, [42] 裴钢. Deficiency of a barrestin2 signal complex contributes to insulin resistance. Nature. 2009, 457: 1146-1149, [43] Li Haisen, Yue Rui, Wei Bin, Gao Ge, Du Jiulin, Pei Gang. Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. The EMBO Journal. 33(12): 1383-1396, http://www.irgrid.ac.cn/handle/1471x/850734.[44] Wei Bin, Pei Gang. microRNAs: critical regulators in Th17 cells and players in diseases. Cellular and Molecular Immunology. 7(3): 175-181, https://www.webofscience.com/wos/woscc/full-record/WOS:000277282200003.