天然产物质谱
中药质量控制及分离分析
代谢及代谢组学研究

1984年7月：大连轻工业学院，工学学士

1998年7月： 中科院长春应化所，理学硕士

 2005年1月： 中科院长春应化所，理学博士

物化前沿（专题）

1.         Fengrui Song，Meng  Cui，Zhiqiang  L iu，Biao  Yu，Shuying  Liu Multiple-stage tandem mass spectrometry For differentiation of isomeric saponins. Rapid Commun. Mass Spectrom.,2004；18:2241-2248

2.         Fengrui Song, Zhiqiang Liu, Shuying Liu, Zongwei Cai. Differentiation and identification of ginsenoside isomers by electrospray ionization tandem mass spectrometry, Anal. Chim. Acta , 2005，531：69-77

3.         Song FR, Liu Ning, Yan CY,Liu ZQ, Liu SY, Non-covalent Interaction Between Oligodeoxynucleotide and Alkaloid Compounds via Negative Ion Electrospray Ionization Mass Spectrometry（I）, Chem. J. Chinese U., 2004, 25（10）：2830－1832

4.         Song FR, Yan CY,Liu Ningh, Liu ZQ, Liu SY. Studies on the Non-covalent Complexes between Oligodeoxynucleotide and Compounds from Some Chinese Herbs,Chinese J. Anal. Chem.2005,33（12）:1743-1746

5.         Liu SY, Song FR,The Application of Mass Spectrometry on the Analysis of Chinese Medicine, Modern Methoology in Chinese Medicine Study, Chemical Industry Press.,2004, 76－84

6.         Chen ML, Song FR, Guo MQ, Liu ZQ, Liu SY. Analysis of Flavonoid Constituents from Leaves of Acanthopanax Senticosus Harms by Electrospray Tandem Mass Spectrometry, Rapid Commun. Mass Spectrom., 2002, 16: 264~ 271

7.         Cai ZW, Song FR, Yang MS, Capillary liquid chromatographic –high -resolution mass spectrometric analysis of ribonucleotides .J. Chromatography A., 2002, 976, 135-143

8.         Guo MQ, Song FR, Bai Y, Liu ZQ, Liu SY  Rapid Analysis of A Triterpenoid Saponin Mixture from Plant Extracts by Electrospray Lonization Tandem Mass Spectrometry. Anal. Sci.,  2002, 18(4) 481-484

9.         Yong Wang, Fengrui Song. Qingxuan Xu, Zhiqiang Liu and Shuying Liu Characterization of aconitine-type alkaloids in the flowers of Aconitum kusnezoffii by electrosprayionization tandem mass spectrometry. J.Mass Spectrom. 2003;38:962-970

10.     Mingquan Guo, Fengrui Song, Zhiqiang Liu. and Shuying Liu, Characterization of non-covalent complexes of rutin with cyclodextrins by electrospray ionization tandemmass spectrometry, J. Mass Spectrom. 2004; 39: 594–599

11.     Yu Bai, Fengrui Song, Maolian Chen, Junpeng Xing, Zhiqiang Liu and Shuying Liu, Application of Multistage Tandem Electrospray Ionisation Mass Spectrometry (ESI-MSn) to characterisation of Rutin-Met al Complex, Anal.Sci., 2004,20, 1147 - 1151.

12.     Wei Wu, Fengrui Song, Cunyu Yan, Zhiqang Liu Shuying Liu.，Structursal analyses of protoberberine alkaloids in medicine herbs by using ESI-FT-ICR-MS and HPLC-ESI-MS， J. pharm. Biomed. Anal.，2005, 378: 437-446，

13.     Guo, MQ; Song, FR; Liu, ZQ; Liu, SY，Characterization of triterpenoidic saponin mixture in crude extracts from leaves of Acanthopanax senticosus Harms by saponin structural correlation and mass spectrometry，Anal. Chim. Acta ,2006，557 (1-2): 198-203 

14.     Xu Zhang, Fengrui Song, Zhiqiang Liu, Shuying Liu. Investigation of the hydrolysis of ginsenosides by high performance liquid chromatography –electrospray ionization mass spectrometry. Planta Medica ,2007,73,1225-1229

15.     Xin Huang, Fengrui Song, Zhiqiang Liu, Shuying Liu. Studies on lignan constituents from Schisandra Chinensis(Turcz.) Bail. Fruits using high-performance liquid chromatography/electrospray ionization multiple-stage tandem mass spectrometry. J.Mass Spectrom., 2007;42:1148-1161

16.     Xin Huang, Fengrui Song, Zhiqiang Liu, Shuying Liu, Structural characterization and identification of dibenzocyclooctadiene lignans in Fructus Schisandrae using electrospray ionization ion trap multiple-stage tandem mass spectrometry and electrospray ionization Fourier transform ion cyclotron resonance multiple-stage tandem  mass spectrometry. Anal. Chim. Acta, 2008,19:141-147

17.     Wei Li, Fengrui Song, Shuying Liu, Zhiqiang Liu. Qualitative and semi-quantitative analysis of quaternary alkaloids in the coptis-scute herb couple by using electrospray mass spectrometry Chem. Res. Chinese U. 2008, 24(2), 162-166

18.     Zhaofu Wang, Meng Cui, Fengrui Song, Lin Lu, Zhiqiang Liu, Shuying Liu Evaluation of Flavonoids Binding to DNA Duplexes by Electrospray Ionization Mass Spectrometry . J Am Soc Mass Spectrom, 2008,43(3):327-335

19.     Mingquan Guo, Suoqing Zhang, Fengrui Song, Daowu Wang, Zhiqiang  Liu and Shuying Liu  Studies on the non-covalent complexes between noleanolic acid and cyclodextrins using electrospray ionization tandem mass spectrometry.  J. Mass Spectrom. 2003;38: 723-731 

20.     Wu Wei, Liu ZQ, Song FR, Liu SY. Structural analysis of selected characteristic flavones by electrospray tandem mass spectrometry. Anal. Sci. 2004; 20: 1103-1105.

21.     Hongjuan Dong , Zhiqiang Liu , Fengrui Song , Zhan Yu , Huilin Li, Shuying Liu. Structural analysis of monoterpene glycosides extracted from Paeonia lactiflora Pall. using electrospray ionization fourier transform ion cyclotron resonance mass spectrometry and high performance liquid chromatography – electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom..2007,21(19),3193-3199

  《中药研究现代方法学》,10. 质谱技术及其在中药分析研究中的应用,化学出版社，2004年

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