基本信息
宋玲  女  博导  中国科学院福建物质结构研究所
电子邮件: songling@fjirsm.ac.cn
通信地址: 福州市杨桥西路155号
邮政编码:

招生信息

   
招生专业
070303-有机化学
招生方向
有机方法学,有机合成
功能化合物作用的分子机理

工作经历

   
工作简历
2008-11~现在, 中科院福建物质结构研究所, 研究员

专利与奖励

   

出版信息

   
发表论文
[1] Xuebo Zhang, Jing Xu, Zhaofeng Sun, Guangling Bian, Ling Song. NMR analysis of the enantiomeric purity of chiral diols by a new chiral boron agent †. RSC Advances. 2022, 12(8): 4692-4696, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8981704/.
[2] Ling Song. Chiral Discrimination of Varied Ammonium Compounds through 1H NMR Using a Binuclear Ti Complex Sensor. Organic Letters. 2020, [3] Xu, Jing, Zhang, Xuebo, Chen, Zhongxiang, Sun, Zhaofeng, Bian, Guangling, Song, Ling. Facile access to chiral beta-homoglutamic acid from 3-cyclohexene-carboxylic acid. SYNTHETIC COMMUNICATIONS[J]. 2020, 50(22): 3475-3480, https://www.webofscience.com/wos/woscc/full-record/WOS:000560967300001.
[4] Sun, Zhaofeng, Chen, Zhongxiang, Wang, Yanqi, Zhang, Xuebo, Xu, Jing, Bian, Guangling, Song, Ling. Chiral Discrimination of Varied Ammonium Compounds through H-1 NMR Using a Binuclear Ti Complex Sensor. ORGANIC LETTERS[J]. 2020, 22(2): 589-593, http://dx.doi.org/10.1021/acs.orglett.9b04373.
[5] Yang, Shiwei, Bian, Guangling, Sa, Rongjian, Song, Ling. Assigning the Absolute Configurations of Chiral Primary Amines Based on Experimental and DFT-Calculated F-19 Nuclear Magnetic Resonance. FRONTIERS IN CHEMISTRY[J]. 2019, 7: https://www.webofscience.com/wos/woscc/full-record/WOS:000468396700001.
[6] Ling Song. A chiral sensor for recognition of varied amines based on 19F NMR signals of newly designed rhodium complexes. Chemical Communications. 2019, [7] Ling Song. Chiral discrimination by a binuclear Pd complex sensor using 31PNMR. Analytical Chemistry. 2019, [8] Chen, Zhongxiang, Yang, Mingxue, Sun, Zhaofeng, Zhang, Xuebo, Xu, Jing, Bian, Guangling, Song, Ling. Chiral Discrimination by a Binuclear Pd Complex Sensor Using P-31{H-1} NMR. ANALYTICAL CHEMISTRY[J]. 2019, 91(22): 14591-14596, [9] Wang, Wei, Xia, Xiaohan, Bian, Guangling, Song, Ling. A chiral sensor for recognition of varied amines based on F-19 NMR signals of newly designed rhodium complexes. CHEMICAL COMMUNICATIONS[J]. 2019, 55(43): 6098-6101, https://www.webofscience.com/wos/woscc/full-record/WOS:000468832200024.
[10] Huang, Huayin, Wang, Yabai, Zong, Hua, Song, Ling. Catalytic asymmetric 1,2-Addition/Lactonization tandem reactions for the syntheses of chiral 3-Substituted phthalides using organozinc reagents. APPLIED ORGANOMETALLIC CHEMISTRY[J]. 2019, 33(1): [11] Chen, Zhongxiang, Fan, Hongjun, Yang, Shiwei, Bian, Guangling, Song, Ling. Chiral sensors for determining the absolute configurations of alpha-amino acid derivatives. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2018, 16(37): 8311-8317, https://www.webofscience.com/wos/woscc/full-record/WOS:000483966100013.
[12] Liu, Yan, Jiang, Longguang, Song, Ling, Tu, Datao, Zheng, Wei, Huang, Ping, Chen, Mingmao, Chen, Xueyuan. Deciphering molecular interaction of binaphthyl compounds with Penicillium expansum lipase: enantioselectivity and reactivity prediction for lipase. MOLECULAR SYSTEMS DESIGN & ENGINEERING[J]. 2018, 3(4): 658-667, https://www.webofscience.com/wos/woscc/full-record/WOS:000441582300008.
[13] Chen Zhongxiang, Fan Hongjun, Yang Shiwei, Bian Guangling, Song Ling. Chiral sensors for determining the absolute configurations of -amino acid derivatives. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2018, 16(37): 6933-6939, http://cas-ir.dicp.ac.cn/handle/321008/166986.
[14] Wang, Yabai, Zong, Hua, Huang, Huayin, Song, Ling. Chiral thiophosphoramide catalyzed asymmetric aryl transfer reactions for the synthesis of functional diarylmethanols. TETRAHEDRON-ASYMMETRY[J]. 2017, 28(1): 90-97, http://dx.doi.org/10.1016/j.tetasy.2016.11.011.
[15] Yang, Shiwei, Bian, Guangling, Chen, Zhongxiang, Xia, Xiaohan, Zhou, Mi, Cui, Caiyan, Song, Ling. Highly efficient synthesis of chiral quaternary 3-aminooxindoles promoted by zinc(II) chloride via Et2Zn-catalysed addition of Grignard reagents to isaltin-derived N-tert-butanesulfinyl ketimines. RSC ADVANCES[J]. 2017, 7(61): 38216-38219, https://www.webofscience.com/wos/woscc/full-record/WOS:000407442000014.
[16] Wang, Yabai, Yang, Shiwei, Bian, Guangling, Song, Ling. A Novel Three-Step Tandem Reaction for Efficient Syntheses of Bulky Anthracenyl Esters from 2-Benzylbenzoic Acids. SYNTHESIS-STUTTGART[J]. 2017, 49(8): 1884-1888, https://www.webofscience.com/wos/woscc/full-record/WOS:000399807700017.
[17] Wang, Yabai, Yang, Shiwei, Bian, Guangling, Song, Ling. A Novel Three-Step Tandem Reaction for Efficient Syntheses of Bulky Anthracenyl Esters from 2-Benzylbenzoic Acids. SYNTHESIS-STUTTGART[J]. 2017, 49(8): 1884-1888, https://www.webofscience.com/wos/woscc/full-record/WOS:000399807700017.
[18] Chen, Mingmao, Liu, Yan, Cao, Huan, Song, Ling, Zhang, Qiqing. The secondary and aggregation structural changes of BSA induced by trivalent chromium: A biophysical study (vol 158, pg 116, 2015). JOURNAL OF LUMINESCENCEnull. 2016, 175: 274-274, https://www.webofscience.com/wos/woscc/full-record/WOS:000374865800043.
[19] Yan Liu, Mingmao Chen, Longguang Jiang, Ling Song. Corrigendum to "Stereoselective interaction of cinchona alkaloid isomers with bovine serum albumin" Food Chem. 181 (2015) 170–178. Food Chemistry. 2016, 1349-1349, http://dx.doi.org/10.1016/j.foodchem.2015.11.125.
[20] Huang, Huayin, Bian, Guangling, Zong, Hua, Wang, Yabai, Yang, Shiwei, Yue, Huifeng, Song, Ling, Fan, Hongjun. Chiral Sensor for Enantiodiscrimination of Varied Acids. ORGANIC LETTERS[J]. 2016, 18(11): 2524-2527, http://cas-ir.dicp.ac.cn/handle/321008/148394.
[21] Zong, Hua, Huang, Huayin, Song, Ling. Catalytic asymmetric addition of aldehydes using organolithium reagents in the presence of commercial available chiral diol ligands. TETRAHEDRON-ASYMMETRY[J]. 2016, 27(20-21): 1069-1074, http://dx.doi.org/10.1016/j.tetasy.2016.08.016.
[22] Lin, Jingjing, Liu, Yan, Chen, Mingmao, Huang, Huayin, Song, Ling. Investigation on the binding activities of citalopram with human and bovine serum albumins (vol 146, pg 114, 2014). JOURNAL OF LUMINESCENCEnull. 2016, 170: 336-336, https://www.webofscience.com/wos/woscc/full-record/WOS:000365606600050.
[23] Mingmao Chen, Yan Liu, Huan Cao, Ling Song, Qiqing Zhang. Corrigendum to: "The secondary and aggregation structural changes of BSA induced by trivalent chromium: A biophysical study" J. Lumin. 158 (2015) 116–124. Journal of Luminescence. 2016, 175: 274-274, http://dx.doi.org/10.1016/j.jlumin.2016.01.002.
[24] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. New insight into molecular interaction of heavy metal pollutant-cadmium(II) with human serum albumin (vol 21, pg 6994 2014). ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCHnull. 2016, 23(5): 4959-4959, https://www.webofscience.com/wos/woscc/full-record/WOS:000371156100095.
[25] Bian, Guangling, Yang, Shiwei, Huang, Huayin, Zong, Hua, Song, Ling, Fan, Hongjun, Sun, Xiaoqiang. Chirality sensing of tertiary alcohols by a novel strong hydrogen-bonding donor - selenourea. CHEMICAL SCIENCE[J]. 2016, 7(2): 932-938, http://cas-ir.dicp.ac.cn/handle/321008/148395.
[26] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. Stereoselective interaction of cinchona alkaloid isomers with bovine serum albumin (vol 181, pg 170, 2015). FOOD CHEMISTRYnull. 2016, 197: 1349-1349, https://www.webofscience.com/wos/woscc/full-record/WOS:000366987500043.
[27] Bian, Guangling, Yang, Shiwei, Huang, Huayin, Zong, Hua, Song, Ling. A bisthiourea-based H-1 NMR chiral sensor for chiral discrimination of a variety of chiral compounds. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2016, 231: 129-134, https://www.webofscience.com/wos/woscc/full-record/WOS:000374330900016.
[28] Chen, Mingmao, Liu, Yan, Cao, Huan, Song, Ling, Zhang, Qiqing. The secondary and aggregation structural changes of BSA induced by trivalent chromium: A biophysical study. JOURNAL OF LUMINESCENCE[J]. 2015, 158: 116-124, http://dx.doi.org/10.1016/j.jlumin.2014.09.021.
[29] Liu, Yan, Lin, Jingjing, Chen, Mingmao, Song, Ling. Investigation on the interaction of the toxicant, gentian violet, with bovine hemoglobin (vol 58, pg 264, 2013). FOOD AND CHEMICAL TOXICOLOGYnull. 2015, 86: 385-385, https://www.webofscience.com/wos/woscc/full-record/WOS:000368203200041.
[30] Huang, Huayin, Zong, Hua, Bian, Guangling, Song, Ling. Chemo- and Enantioselective Addition and beta-Hydrogen Transfer Reduction of Carbonyl Compounds with Diethylzinc Reagent in One Pot Catalyzed by a Single Chiral Organometallic Catalyst. JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 80(24): 12614-12619, https://www.webofscience.com/wos/woscc/full-record/WOS:000366877900071.
[31] Huang, Huayin, Zong, Hua, Bian, Guangling, Song, Ling. Catalytic asymmetric beta-hydrogen transfer reduction of alpha-trilluoromethyl aromatic ketones with diethylzinc. TETRAHEDRON-ASYMMETRY[J]. 2015, 26(15-16): 835-839, https://www.webofscience.com/wos/woscc/full-record/WOS:000360597100009.
[32] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. Stereoselective interaction of cinchona alkaloid isomers with bovine serum albumin. FOOD CHEMISTRY[J]. 2015, 181: 170-178, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201903250003887LS.
[33] Bian, Guangling, Fan, Hongjun, Huang, Huayin, Yang, Shiwei, Zong, Hua, Song, Ling, Yang, Genjin. Highly Effective Configurational Assignment Using Bisthioureas as Chiral Solvating Agents in the Presence of DABCO. ORGANIC LETTERS[J]. 2015, 17(6): 1369-1372, http://cas-ir.dicp.ac.cn/handle/321008/146127.
[34] Yan Liu, Jingjing Lin, Mingmao Chen, Ling Song. Corrigendum to "Investigation on the interaction of the toxicant, gentian violet, with bovine hemoglobin" Food Chem. Toxicol. 58 (2013) 264–272. Food and Chemical Toxicology. 2015, 86: 385-385, http://dx.doi.org/10.1016/j.fct.2015.11.006.
[35] Li, Fangling, Huang, Huayin, Zong, Hua, Bian, Guangling, Song, Ling. Investigation on the asymmetric addition reactions between varied nonaromatic aldehydes and diethylzinc catalyzed by chiral phosphoramide and thiophosphorodiamide ligands. TETRAHEDRON LETTERS[J]. 2015, 56(16): 2071-2076, http://dx.doi.org/10.1016/j.tetlet.2015.03.020.
[36] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. Stereoselective interaction of cinchona alkaloid isomers with bovine serum albumin. Food Chemistry[J]. 2015, 170-178, http://dx.doi.org/10.1016/j.foodchem.2015.02.040.
[37] Huang Huayin, Zong Hua, Bian Guangling, Yue Huifeng, Song Ling. Correlating the effects of the N-substituent sizes of chiral 1,2-amino phosphinamide ligands on enantioselectivities in catalytic asymmetric Henry reaction using physical steric parameters.. The Journal of organic chemistry. 2014, [38] Liu, Yan, Chen, Mingmao, Wang, Shuaihua, Lin, Jingjing, Cai, Lizhen, Song, Ling. New insight into the stereoselective interactions of quinine and quinidine, with bovine serum albumin. JOURNAL OF MOLECULAR RECOGNITION[J]. 2014, 27(5): 239-249, https://www.webofscience.com/wos/woscc/full-record/WOS:000333743800001.
[39] Zong, Hua, Huang, Huayin, Bian, Guangling, Song, Ling. Fine-Tuning the Structures of Chiral Diamine Ligands in the Catalytic Asymmetric Aldol Reactions of Trifluoromethyl Aromatic Ketones with Linear Aliphatic Ketones. JOURNAL OF ORGANIC CHEMISTRY[J]. 2014, 79(23): 11768-11773, https://www.webofscience.com/wos/woscc/full-record/WOS:000346038300048.
[40] Huang, Huayin, Zong, Hua, Shen, Bin, Yue, Huifeng, Bian, Guangling, Song, Ling. QSAR analysis of the catalytic asymmetric ethylation of ketone using physical steric parameters of chiral ligand substituents. TETRAHEDRON[J]. 2014, 70(6): 1289-1297, http://dx.doi.org/10.1016/j.tet.2013.12.054.
[41] Yue, Huifeng, Huang, Huayin, Bian, Guangling, Zong, Hua, Li, Fangling, Song, Ling. Enantioselectivity switch controlled by N,N '-di- or N,N,N ',N '-tetra-substituted chiral thiophosphorodiamide ligands, structural relatives of thioureas, in catalytic additions of diethylzinc to aldehydes. TETRAHEDRON-ASYMMETRY[J]. 2014, 25(2): 170-180, http://dx.doi.org/10.1016/j.tetasy.2013.12.014.
[42] Lin, Jingjing, Liu, Yan, Chen, Mingmao, Huang, Huayin, Song, Ling. Investigation on the binding activities of citalopram with human and bovine serum albumins. JOURNAL OF LUMINESCENCE[J]. 2014, 146: 114-122, http://dx.doi.org/10.1016/j.jlumin.2013.09.054.
[43] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. New insight into molecular interaction of heavy metal pollutant-cadmium(II) with human serum albumin. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH[J]. 2014, 21(11): 6994-7005, https://www.webofscience.com/wos/woscc/full-record/WOS:000336371000021.
[44] Huang, Huayin, Zong, Hua, Bian, Guangling, Yue, Huifeng, Song, Ling. Correlating the Effects of the N-Substituent Sizes of Chiral 1,2-Amino Phosphinamide Ligands on Enantioselectivities in Catalytic Asymmetric Henry Reaction Using Physical Steric Parameters. JOURNAL OF ORGANIC CHEMISTRY[J]. 2014, 79(20): 9455-9464, https://www.webofscience.com/wos/woscc/full-record/WOS:000343527200004.
[45] Liu, Yan, Chen, Mingmao, Luo, Zhipu, Lin, Jingjing, Song, Ling. Investigation on the site-selective binding of bovine serum albumin by erlotinib hydrochloride. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS[J]. 2013, 31(10): 1160-1174, https://www.webofscience.com/wos/woscc/full-record/WOS:000324002100012.
[46] Bian, Guangling, Yang, Shiwei, Huang, Huayin, Song, Ling. A New Method for the Synthesis of Enantiomerically Pure Betti Base. SYNTHESIS-STUTTGART[J]. 2013, 45(7): 899-902, https://www.webofscience.com/wos/woscc/full-record/WOS:000316451500011.
[47] Shen, Bin, Huang, Huayin, Bian, Guangling, Zong, Hua, Song, Ling. Highly Efficient Asymmetric Additions of Diethylzinc to Aldehydes Triply Activated by Chiral Phosphoramide-Zn(II) Complexes Derived From Cinchona Alkaloids. CHIRALITY[J]. 2013, 25(9): 561-566, https://www.webofscience.com/wos/woscc/full-record/WOS:000325921900010.
[48] Liu, Yan, Lin, Jingjing, Chen, Mingmao, Song, Ling. Investigation on the interaction of the toxicant, gentian violet, with bovine hemoglobin. FOOD AND CHEMICAL TOXICOLOGY[J]. 2013, 58: 264-272, http://dx.doi.org/10.1016/j.fct.2013.04.048.
[49] Bian, Guangling, Fan, Hongjun, Yang, Shiwei, Yue, Huifeng, Huang, Huayin, Zong, Hua, Song, Ling. A Chiral Bisthiourea as a Chiral Solvating Agent for Carboxylic Acids in the Presence of DMAP. JOURNAL OF ORGANIC CHEMISTRY[J]. 2013, 78(18): 9137-9142, http://www.irgrid.ac.cn/handle/1471x/858482.
[50] Zong, Hua, Huang, Huayin, Bian, Guangling, Song, Ling. Synergistic effect of achiral quaternary ammonium salt on asymmetric additions of diethylzinc to aldehydes. TETRAHEDRON LETTERS[J]. 2013, 54(21): 2722-2725, http://dx.doi.org/10.1016/j.tetlet.2013.03.066.
[51] Liu, Yan, Chen, Mingmao, Song, Ling. Comparing the effects of Fe(III) and Cu(II) on the binding affinity of erlotinib to bovine serum albumin using spectroscopic methods. JOURNAL OF LUMINESCENCE[J]. 2013, 134: 515-523, http://dx.doi.org/10.1016/j.jlumin.2012.07.036.
[52] Lin, Jingjing, Liu, Yan, Liu, Lingrong, Song, Ling. Studies on the Toxic Interaction Mechanism between 2-Naphthylamine and Herring Sperm DNA. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY[J]. 2013, 27(5): 279-285, http://www.corc.org.cn/handle/1471x/2221473.
[53] Ling Song. Efficient catalytic transition-metal-free conditions for nucleophilic addition of phenylacetylene to aromatic ketones. Tetrahedron letters. 2012, [54] Huang, Huayin, Zong, Hua, Bian, Guangling, Song, Ling. Constructing a Quantitative Correlation between N-Substituent Sizes of Chiral Ligands and Enantioselectivities in Asymmetric Addition Reactions of Diethylzinc with Benzaldehyde. JOURNAL OF ORGANIC CHEMISTRY[J]. 2012, 77(22): 10427-10434, https://www.webofscience.com/wos/woscc/full-record/WOS:000311073000052.
[55] Zong, Hua, Huang, Huayin, Liu, Junfeng, Bian, Guangling, Song, Ling. Added-Metal-Free Catalytic Nucleophilic Addition of Grignard Reagents to Ketones. JOURNAL OF ORGANIC CHEMISTRY[J]. 2012, 77(10): 4645-4652, https://www.webofscience.com/wos/woscc/full-record/WOS:000304129400014.
[56] Liu, Junfeng, Lin, Jin, Song, Ling. Efficient catalytic transition-metal-free conditions for nucleophilic addition of arylacetylenes to aromatic ketones. TETRAHEDRON LETTERS[J]. 2012, 53(17): 2160-2163, http://dx.doi.org/10.1016/j.tetlet.2012.02.058.
[57] Bian, Guangling, Huang, Huayin, Zong, Hua, Song, Ling. The Syntheses of new Camphorsulfonylated Ligands Derived from 2-Amino-2'-Hydroxy-1,1'-Binaphthyl and Their Enantioselectivities in the Addition of Dialkylzinc Reagents to Aldehydes. CHIRALITY[J]. 2012, 24(10): 825-832, https://www.webofscience.com/wos/woscc/full-record/WOS:000309240200009.
[58] Ding, Lei, Lin, Lirong, Liu, Chengyong, Li, Hongkun, Qin, Anjun, Liu, Yan, Song, Ling, Zhang, Hui, Tang, Ben Zhong, Zhao, Yufen. Concentration effects in solid-state CD spectra of chiral atropisomeric compounds. NEW JOURNAL OF CHEMISTRY[J]. 2011, 35(9): 1781-1786, http://ir.fjirsm.ac.cn/handle/335002/1129.
[59] 宗华, 黄华银, 边广岭, 宋玲, 冷一欣. 新型磺酰胺手性配体的合成与表征. 化学试剂[J]. 2011, 33(9): 773-776, http://lib.cqvip.com/Qikan/Article/Detail?id=39226719.
[60] 黄华银, 姜艳, 边广岭, 宗华, 宋玲, 孙小强. L-缬氨酸衍生的磺酰胺类配体的合成及其在二乙基锌对苯甲醛的不对称加成中的应用. 合成化学[J]. 2011, 19(3): 295-298, http://lib.cqvip.com/Qikan/Article/Detail?id=37924242.
[61] Zong, Hua, Huang, HuaYin, Hu, Bing, Bian, GuangLing, Song, Ling. 2,2 '-Bis(methoxymethoxy)-3,3 '-diphenyl-1,1 '-binaphthalene. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE[J]. 2011, 67: O222-U3316, http://ir.fjirsm.ac.cn/handle/335002/1774.
[62] Liu, Yan, Chen, Mingmao, Bian, Guangling, Liu, Junfeng, Song, Ling. Spectroscopic investigation of the interaction of the toxicant, 2-naphthylamine, with bovine serum albumin. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY[J]. 2011, 25(6): 362-368, http://ir.fjirsm.ac.cn/handle/335002/1402.
[63] 宋玲. 稀土过渡金属异多核金属化合物的结构和性能研究. 1997, 90-, http://ir.fjirsm.ac.cn/handle/350002/7388.

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