基本信息
黄蔚 男 硕导 上海药物研究所
电子邮件:huangwei@simm.ac.cn
通信地址:上海祖冲之路555号
邮政编码:

招生信息

   
招生专业
100701-药物化学
070321-化学生物学
招生方向
药物合成化学

出版信息

   
发表论文
[1] Liu, Bo, Yu, Xueni, Liu, Liping, Wang, Lei, Wang, Jie, Huang, Qianqian, Xu, Zhongliang, Luo, Cheng, Lou, Liguang, Huang, Wei, Yang, Weibo. Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance. JOURNAL OF MEDICINAL CHEMISTRY. 2023, http://dx.doi.org/10.1021/acs.jmedchem.2c01424.
[2] Hao Wang, Zhongyu Li, Xiangyang Chen, Jonathan J Wong, Tongyu Bi, Xiankun Tong, Zhongliang Xu, Mingyue Zhen, Yunhui Wan, Li Tang, Bo Liu, Xinlei Zong, Dandan Xu, Jianping Zuo, Li Yang, Wei Huang, Kendall N Houk, Weibo Yang. Multicomponent coupling and macrocyclization enabled by Rh(III)-catalyzed dual C–H activation: Macrocyclic oxime inhibitor of influenza H1N1. CHEM[J]. 2023, 9(3): 607-623, http://dx.doi.org/10.1016/j.chempr.2022.10.019.
[3] Wenjing Ma, Zhuojia Xu, Yuhan Jiang, Jialin Liu, Dandan Xu, Wei Huang, Tiehai Li. Divergent Enzymatic Assembly of a Comprehensive 64‐Membered IgG N ‐Glycan Library for Functional Glycomics. ADVANCED SCIENCE. 2023, 10(30): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602528/.
[4] Dongliang Guan, Jian Li, Feifei Chen, Jiaqi Li, Xiaolei Bian, Yue Yu, Xinxin Feng, Lefu Lan, Wei Huang. A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2023, 259: http://dx.doi.org/10.1016/j.ejmech.2023.115638.
[5] Shi, Wei, Zhang, Jianxin, Liu, Liya, Li, Wanzhen, Liu, Zhi, Ren, Anni, Wang, Jie, Tang, Caihong, Yang, Yang, Xu, Dandan, Huang, Qianqian, Wang, Yongqin, Luo, Caili, Huang, Wei, Tang, Feng. Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody-Drug Conjugates. JOURNAL OF MEDICINAL CHEMISTRY[J]. 2022, [6] Zou, Xiangman, Liu, Zhi, Liu, Liya, Shi, Wei, Li, Wanzhen, Guo, Zifen, Tang, Feng, Huang, Wei. Enhanced transglycosylation activity of an Endo-F3 mutant by ligand-directed localization. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2022, 20(15): 3086-3095, http://dx.doi.org/10.1039/d2ob00030j.
[7] Long, Yiru, Sun, Jianhua, Song, TianZhang, Liu, Tingting, Tang, Feng, Zhang, Xinxin, Ding, Longfei, Miao, Yunqiu, Zhu, Weiliang, Pan, Xiaoyan, An, Qi, Qin, Mian, Tong, Xiankun, Peng, Xionghua, Yu, Pan, Zhu, Peng, Xu, Jianqing, Zhang, Xiaoyan, Zhang, Yachun, Liu, Datao, Chen, Ben, Chen, Huilin, Zhang, Leike, Xiao, Gengfu, Zuo, Jianping, Tang, Wei, Zhou, Ji, Li, Heng, Xu, Zhijian, Zheng, HongYi, Long, XinYan, Qin, Qiuping, Gan, Yong, Ren, Jin, Huang, Wei, Zheng, YongTang, Jin, Guangyi, Gong, Likun. CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity. CELL DISCOVERY[J]. 2022, 8(1): https://doaj.org/article/3c59c092141d418c8f84164569078712.
[8] Zeng, Yue, Shi, Wei, Dong, Qian, Li, Wanzhen, Zhang, Jianxin, Ren, Xuelian, Tang, Caihong, Liu, Bo, Song, Yuanli, Wu, Yali, Diao, Xingxing, Zhou, Hu, Huang, He, Tang, Feng, Huang, Wei. A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 61(36): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000830729300001.
[9] Lei, E, Tao, Huanyu, Jiao, Shang, Yang, Anming, Zhou, Yu, Wang, Min, Wen, Kang, Wang, Yi, Chen, Zhiyong, Chen, Xianhui, Song, Junfeng, Zhou, Cailing, Huang, Wei, Xu, Lili, Guan, Dongliang, Tan, Cuiyan, Liu, Haoran, Cai, Qingyun, Zhou, Kai, Modica, Justin, Huang, ShengYou, Huang, Wei, Feng, Xinxin. Potentiation of Vancomycin: Creating Cooperative Membrane Lysis through a "Derivatization-for-Sensitization" Approach. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2022, 144(23): 10622-10639, http://dx.doi.org/10.1021/jacs.2c03784.
[10] Chen, Yao, Tang, Feng, Qin, Hongqiang, Yue, Xuyang, Nie, Yongzhan, Huang, Wei, Ye, Mingliang. Endo-M Mediated Chemoenzymatic Approach Enables Reversible Glycopeptide Labeling for O-GlcNAcylation Analysis. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, http://dx.doi.org/10.1002/anie.202117849.
[11] Zeng, Yue, Tang, Feng, Shi, Wei, Dong, Qian, Huang, Wei. Recent advances in synthetic glycoengineering for biological applications. CURRENT OPINION IN BIOTECHNOLOGYnull. 2022, 74: 247-255, http://dx.doi.org/10.1016/j.copbio.2021.12.008.
[12] Shi, Wei, Li, Wanzhen, Zhang, Jianxin, Li, Tiehai, Song, Yakai, Zeng, Yue, Dong, Qian, Lin, Zeng, Gong, Likun, Fan, Shuquan, Tang, Feng, Huang, Wei. One-step synthesis of site-specific antibody-drug conjugates by reprograming IgG glycoengineering with LacNAc-based substrates. ACTA PHARMACEUTICA SINICA B[J]. 2022, 12(5): 2417-2428, http://dx.doi.org/10.1016/j.apsb.2021.12.0132211-3835.
[13] Li, Jian, Zhu, Yue, Liu, Bo, Tang, Feng, Zheng, Xing, Huang, Wei. An Atom-Economic Inverse Solid-Phase Peptide Synthesis Using Bn or BcM Esters of Amino Acids. ORGANIC LETTERS[J]. 2021, 23(19): 7571-7574, http://dx.doi.org/10.1021/acs.orglett.1c02769.
[14] Shi, Weiwei, Chen, Feifei, Zou, Xiangman, Jiao, Shang, Wang, Siqi, Hu, Yu, Lan, Lefu, Tang, Feng, Huang, Wei. Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2021, 45: http://dx.doi.org/10.1016/j.bmcl.2021.128122.
[15] Song, Yakai, Deng, Xiaojie, Shi, Wei, Tang, Feng, Huang, Wei, Gong, Likun, Qin, Qiuping. A homogeneous time-resolved fluorometric energy transfer assay for the binding assessment of FcRn with IgG antibodies. JOURNAL OF IMMUNOLOGICAL METHODS[J]. 2021, 499: http://dx.doi.org/10.1016/j.jim.2021.113180.
[16] Pan, Deng, Tang, Yubo, Tong, Jiao, Xie, Chengmei, Chen, Jiaxi, Feng, Chunchao, Hwu, Patrick, Huang, Wei, Zhou, Dapeng. An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer. CANCER MEDICINE[J]. 2020, 9(24): 9529-9540, https://www.doi.org/10.1002/cam4.3554.
[17] Lu, Dan, Yin, Hongli, Wang, Siyao, Tang, Feng, Huang, Wei, Wang, Ping. Chemical Synthesis of the Homogeneous Granulocyte-Macrophage Colony-Stimulating Factor Through Se-Auxiliary-Mediated Ligation. JOURNAL OF ORGANIC CHEMISTRY[J]. 2020, 85(3): 1652-1660, https://www.webofscience.com/wos/woscc/full-record/WOS:000513080700034.
[18] Ming Li, Yaqiang Bai, Jiaorui Zhou, Wei Huang, Jingyu Yan, Jia Tao, Qingjie Fan, Yang Liu, Di Mei, Qiulong Yan, Jieli Yuan, Patrice Malard, Zhongfu Wang, Jianguo Gu, Naoyuki Tanigchi, Wenzhe Li. Core Fucosylation of Maternal Milk N-Glycan Evokes B Cell Activation by Selectively Promoting the l-Fucose Metabolism of Gut Bifidobacterium spp. and Lactobacillus spp.. MBIO[J]. 2019, 10(2): IR_Article.
[19] Zhao, Kai, Tang, Feng, Shi, Wei, Hong, Haofei, Zhou, Zhifang, Huang, Wei, Wu, Zhimeng. One-step immobilization and purification of genetic engineering CBD fusion EndoS on cellulose for antibodies Fc-glycan remodeling. BIOORGANIC CHEMISTRY[J]. 2019, 91: 103114-, http://dx.doi.org/10.1016/j.bioorg.2019.103114.
[20] 李名洁, 唐峰, 郭伟来, 徐莉英, 黄蔚. 蛋黄及其提取物中唾液酸糖肽的分离与测定. 沈阳药科大学学报[J]. 2018, 35(9): 769-, http://lib.cqvip.com/Qikan/Article/Detail?id=676331666.
[21] Zhou, Dapeng, Xu, Lan, Huang, Wei, Tonn, Torsten. Epitopes of MUC1 Tandem Repeats in Cancer as Revealed by Antibody Crystallography: Toward Glycopeptide Signature-Guided Therapy. MOLECULES[J]. 2018, 23(6): https://doaj.org/article/78cd2501b0134d6b8c4929a25d7f79e7.
[22] Zhou, Bin, Faridoon, Tian, Xiaobo, Li, Jian, Guan, Dongliang, Zheng, Xing, Guo, Yu, Huang, Wei. On-resin peptide ligation via C-terminus benzyl ester. CHINESE CHEMICAL LETTERS[J]. 2018, 29(7): 1123-1126, http://dx.doi.org/10.1016/j.cclet.2018.03.021.
[23] Yang, Liyun, Liu, Xiaofang, Yang, Yang, Yang, Linlin, Liu, Kaiwen, Tang, Yubo, Zhang, Min, Tan, Minjia, Cheng, Shanmei, Xu, Yechun, Yang, Huaiyu, Liu, Zhijie, Song, Gaojie, Huang, Wei. Biochemical features of the adhesion G protein-coupled receptor CD97 related to its auto-proteolysis and HeLa cell attachment activities. ACTA PHARMACOLOGICA SINICA[J]. 2017, 38(1): 56-68, [24] Huang Yu. Asp side-chain benzyl ester as a multi-functionalization precursor for synthesis of branched and cyclic RGD peptides. Synlett. 2017, [25] Li, Xiaona, Zhou, Mang, Huang, Wei, Yang, Huaiyu. N-glycosylation of the beta(2) adrenergic receptor regulates receptor function by modulating dimerization. FEBS JOURNAL[J]. 2017, 284(13): 2004-2018, http://dx.doi.org/10.1111/febs.14098.
[26] 熊伦, 管栋梁, 李剑, 黄蔚. 特拉万星合成工艺研究. 中国药科大学学报[J]. 2017, 48(2): 172-, http://lib.cqvip.com/Qikan/Article/Detail?id=671956644.
[27] Guo, Weilai, Tang, Feng, Qin, Ken, Zhou, Mang, Le, Zhiping, Huang, Wei. Glycoengineering and glycosite-specific labeling of serum IgGs from various species. CARBOHYDRATE RESEARCH[J]. 2017, 446: 32-39, http://dx.doi.org/10.1016/j.carres.2017.05.001.
[28] Peng, Huige, Chen, Binfan, Huang, Wei, Tang, Yubo, Jiang, Yifan, Zhang, Wenyuan, Huang, Yongzhuo. Reprogramming Tumor-Associated Macrophages To Reverse EGFR(T790M) Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat. NANO LETTERS[J]. 2017, 17(12): 7684-7690, https://www.webofscience.com/wos/woscc/full-record/WOS:000418393300070.
[29] Pan, Zhenzhen, Kang, Xuejia, Zeng, Yuaner, Zhang, Wenyuan, Peng, Huige, Wang, Jinyu, Huang, Wei, Wang, Huiyuan, Shen, Youqing, Huang, Yongzhuo. A mannosylated PEI-CPP hybrid for TRAIL gene targeting delivery for colorectal cancer therapy. POLYMER CHEMISTRY[J]. 2017, 8(35): 5275-5285, http://dx.doi.org/10.1039/c7py00882a.
[30] Huang Yu. eprogramming tumor-associated macrophages to reverse EGFRT790M resistance by dual-targeting codelivery of gefitinib/vorinostat.. Nano Lett.. 2017, [31] Cai, Deqin, Xun, Chaochao, Tang, Feng, Tian, Xiaobo, Yang, Liyun, Ding, Kan, Li, Wenzhe, Le, Zhiping, Huang, Wei. Glycoconjugate probes containing a core-fucosylated N-glycan trisaccharide for fucose lectin identification and purification. CARBOHYDRATE RESEARCHnull. 2017, 449: 143-152, http://dx.doi.org/10.1016/j.carres.2017.07.011.
[32] Yubo Tang, Feng Tang, Yang Yang, Lei Zhao, Hu Zhou, Jinhua Dong, Wei Huang. Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control. SCIENTIFIC REPORTS[J]. 2017, 7(1): https://doaj.org/article/9ae51b60849a462e861cb18db59f92ee.
[33] Huang Yu. Chemoenzymatic synthesis of glycoengineered IgG antibodies and glycosite-specific antibody-drug conjugates (gsADCs). Nature Protocols. 2017, [34] Cai, Deqin, Guan, Dongliang, Ding, Kan, Huang, Wei. Regioselective protection of xylose for efficient synthesis of arabino-alpha-1,3-xylosides. TETRAHEDRON LETTERS[J]. 2017, 58(45): 4293-4295, https://www.webofscience.com/wos/woscc/full-record/WOS:000414107300017.
[35] Huang Yu. Real-time analysis of drug-antibody ratio of antibody-drug conjugates for synthesis, process optimization, and quality control.. Sci. Rep.. 2017, [36] Tian, Xiaobo, Li, Jie, Huang, Wei. Optimal peptide hydrazide ligation with C-terminus Asp, Asn, and Gln hydrazides. TETRAHEDRON LETTERS[J]. 2016, 57(38): 4264-4267, http://dx.doi.org/10.1016/j.tetlet.2016.07.101.
[37] Qu, Jin, Yu, Hongtao, Li, Fenge, Zhang, Chunlei, Trad, Ahmad, Broks, Cory, Zhang, Bin, Gong, Ting, Guo, Zhi, Li, Yunsen, Ragupathi, Govind, Lou, Yanyan, Hwu, Patrick, Huang, Wei, Zhou, Dapeng. Molecular basis of antibody binding to mucin glycopeptides in lung cancer. INTERNATIONAL JOURNAL OF ONCOLOGY[J]. 2016, 48(2): 587-594, https://www.webofscience.com/wos/woscc/full-record/WOS:000366897500016.
[38] Huang Yu. Biochemical features of the adhesion G protein-coupled receptor CD97 for its functions of auto-proteolysis and HeLa cell attachment. Acta Pharmacologica Sinica. 2016, [39] Tang, Feng, Yang, Yang, Tang, Yubo, Tang, Shuai, Yang, Liyun, Sun, Bingyang, Jiang, Bofeng, Dong, Jinhua, Liu, Hong, Huang, Min, Geng, MeiYu, Huang, Wei. One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2016, 14(40): 9501-9518, http://www.corc.org.cn/handle/1471x/2374782.
[40] Huang Yu. A new strategy for synthesis of branched cyclic peptide by Asn side-chain hydrazine ligation. Chin. Chem. Lett. 2015, [41] Lu, Jian, Tian, XiaoBo, Huang, Wei. A new strategy for synthesis of branched cyclic peptide by Asn side-chain hydrazide ligation. CHINESE CHEMICAL LETTERS[J]. 2015, 26(8): 946-950, http://dx.doi.org/10.1016/j.cclet.2015.05.016.
[42] 孙冰洋, 田小波, 黄蔚, 董金华. 超声条件下选择性脱除Fmoc-Asn(Ac_3GlcNAc) -OH的O-乙酰基. 沈阳药科大学学报[J]. 2015, 32(5): 353-, [43] 黄蔚. 天然产物在抗体药物的糖基化改造及ADC药物研发中的应用. 2014, 6-, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CPFD&dbname=CPFDLAST2018&filename=ZGHY201411005005&v=MTkzODFpbnRVNy9OSVY0ZFB5ckRkN0c0SDlYTnJvOUZZZXNQQ1JOS3VoZGhuajk4VG5qcXF4ZEVlTU9VS3JpZlplWnZI.
[44] Wang, Denong, Bhat, Roopa, Sobel, Raymond A, Huang, Wei, Wang, LaiXi, Olsson, Tomas, Steinman, Lawrence. Uncovering Cryptic Glycan Markers in Multiple Sclerosis (MS) and Experimental Autoimmune Encephalomyelitis (EAE). DRUG DEVELOPMENT RESEARCH[J]. 2014, 75(3): 172-188, https://www.doi.org/10.1002/ddr.21169.
[45] Sun, Bingyang, Bao, Wenzheng, Tian, Xiaobo, Li, Mingjing, Liu, Hong, Dong, Jinhua, Huang, Wei. A simplified procedure for gram-scale production of sialylglycopeptide (SGP) from egg yolks and subsequent semi-synthesis of Man(3)GlcNAc oxazoline. CARBOHYDRATE RESEARCH[J]. 2014, 396: 62-69, http://dx.doi.org/10.1016/j.carres.2014.07.013.
[46] Wang, Helen, Huang, Wei, Orwenyo, Jared, Banerjee, Aditi, Vasta, Gerardo R, Wang, LaiXi. Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3. BIOORGANIC & MEDICINAL CHEMISTRY[J]. 2013, 21(7): 2037-2044, http://dx.doi.org/10.1016/j.bmc.2013.01.028.
[47] Orwenyo, Jared, Huang, Wei, Wang, LaiXi. Chemoenzymatic synthesis and lectin recognition of a selectively fluorinated glycoprotein. BIOORGANIC & MEDICINAL CHEMISTRY[J]. 2013, 21(16): 4768-4777, http://dx.doi.org/10.1016/j.bmc.2013.03.009.
[48] Amin, Mohammed N, McLellan, Jason S, Huang, Wei, Orwenyo, Jared, Burton, Dennis R, Koff, Wayne C, Kwong, Peter D, Wang, LaiXi. Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies. NATURE CHEMICAL BIOLOGY[J]. 2013, 9(8): 521-526, https://www.webofscience.com/wos/woscc/full-record/WOS:000321952700012.
[49] Wang, Denong, Dafik, Laila, Nolley, Rosalie, Huang, Wei, Wolfinger, Russell D, Wang, LaiXi, Peehl, Donna M. Anti-Oligomannose Antibodies as Potential Serum Biomarkers of Aggressive Prostate Cancer. DRUG DEVELOPMENT RESEARCH[J]. 2013, 74(2): 65-80, https://www.webofscience.com/wos/woscc/full-record/WOS:000316463700002.
[50] Huang, Wei, Giddens, John, Fan, ShuQuan, Toonstra, Christian, Wang, LaiXi. Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2012, 134(29): 12308-12318, https://www.webofscience.com/wos/woscc/full-record/WOS:000306724500080.
[51] Song, Wei, Delyria, Elizabeth S, Chen, Jieqing, Huang, Wei, Lee, Jun Soo, Mittendorf, Elizabeth A, Ibrahim, Nuhad, Radvanyi, Laszlo G, Li, Yunsen, Lu, Hongzhou, Xu, Huaxi, Shi, Yinqiang, Wang, LaiXi, Ross, Jeremy A, Rodrigues, Silas P, Almeida, Igor C, Yang, Xifeng, Qu, Jin, Schocker, Nathaniel S, Michael, Katja, Zhou, Dapeng. MUC1 glycopeptide epitopes predicted by computational glycomics. INTERNATIONAL JOURNAL OF ONCOLOGY[J]. 2012, 41(6): 1977-1984, http://dx.doi.org/10.3892/ijo.2012.1645.
[52] Huang Yu. Remarkable transglycosylation activity of glycosynthase mutants of Endo-D, an endo-beta-N-acetylglucosaminidase from Streptococcus pneumonia.. J. Biol. Chem.. 2012, [53] Amin, Mohammed N, Huang, Wei, Mizanur, Rahman M, Wang, LaiXi. Convergent Synthesis of Homogeneous Glc(1)Man(9)GlcNAc(2)-Protein and Derivatives as Ligands of Molecular Chaperones in Protein Quality Control. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2011, 133(36): 14404-14417, https://www.webofscience.com/wos/woscc/full-record/WOS:000295193700047.
[54] Huang, Wei, Li, Jie, Wang, LaiXi. Unusual Transglycosylation Activity of Flavobacterium meningosepticum Endoglycosidases Enables Convergent Chemoenzymatic Synthesis of Core Fucosylated Complex N-Glycopeptides. CHEMBIOCHEM[J]. 2011, 12(6): 932-941, https://www.webofscience.com/wos/woscc/full-record/WOS:000289214900017.
[55] Guozhang Zou, Hirofumi Ochiai, Wei Huang, Qiang Yang, Cishan Li, LaiXi Wang. Chemoenzymatic Synthesis and Fcγ Receptor Binding of Homogeneous Glycoforms of Antibody Fc Domain. Presence of a Bisecting Sugar Moiety Enhances the Affinity of Fc to FcγIIIa Receptor. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2011, 133(46): 18975-18991, [56] Umekawa, Midori, Li, Cishan, Higashiyama, Takayuki, Huang, Wei, Ashida, Hisashi, Yamamoto, Kenji, Wang, LaiXi. Efficient Glycosynthase Mutant Derived from Mucor hiemalis Endo-beta-N-acetylglucosaminidase Capable of Transferring Oligosaccharide from Both Sugar Oxazoline and Natural N-Glycan. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2010, 285(1): 511-521, http://dx.doi.org/10.1074/jbc.M109.059832.
[57] Schwarz, Flavio, Huang, Wei, Li, Cishan, Schulz, Benjamin L, Lizak, Christian, Palumbo, Alessandro, Numao, Shin, Neri, Dario, Aebi, Markus, Wang, LaiXi. A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation. NATURE CHEMICAL BIOLOGY[J]. 2010, 6(4): 264-266, http://dx.doi.org/10.1038/NCHEMBIO.314.
[58] Yang, Qiang, Li, Cishan, Wei, Yadong, Huang, Wei, Wang, LaiXi. Expression, Glycoform Characterization, and Antibody-Binding of HIV-1 V3 Glycopeptide Domain Fused with Human IgG1-Fc. BIOCONJUGATE CHEMISTRY[J]. 2010, 21(5): 875-883, https://www.webofscience.com/wos/woscc/full-record/WOS:000277683300012.
[59] Huang Yu. Endo-beta-N-acetylglucosaminidase shows transglycosylation Activity on complex type N-glycan oxazolines. One-pot conversion of ribonuclease B to sialylated ribonuclease C. ChemBioChem. 2010, [60] Huang, Wei, Zhang, Xinyu, Ju, Tongzhong, Cummings, Richard D, Wang, LaiXi. Expeditious chemoenzymatic synthesis of CD52 glycopeptide antigens. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2010, 8(22): 5224-5233, https://www.webofscience.com/wos/woscc/full-record/WOS:000283602000026.
[61] Wang, LaiXi, Huang, Wei. Enzymatic transglycosylation for glycoconjugate synthesis. CURRENT OPINION IN CHEMICAL BIOLOGYnull. 2009, 13(5-6): 592-600, http://dx.doi.org/10.1016/j.cbpa.2009.08.014.
[62] Ochiai, Hirofumi, Huang, Wei, Wang, LaiXi. Endo-beta-N-acetylglucosaminidase-catalyzed polymerization of beta-Glcp-(1 -> 4)-GlcpNAc oxazoline: a revisit to enzymatic transglycosylation. CARBOHYDRATE RESEARCH[J]. 2009, 344(5): 592-598, https://www.webofscience.com/wos/woscc/full-record/WOS:000265321500005.
[63] Huang, Wei, Groothuys, Stan, Heredia, Alonso, Kuijpers, Brian H M, Rutjes, Floris P J T, van Delft, Floris L, Wang, LaiXi. Enzymatic Glycosylation of Triazole-Linked GlcNAc/Glc-Peptides: Synthesis, Stability and Anti-HIV Activity of Triazole-Linked HIV-1 gp41 Glycopeptide C34 Analogues. CHEMBIOCHEM[J]. 2009, 10(7): 1234-1242, https://www.webofscience.com/wos/woscc/full-record/WOS:000266382900015.
[64] Huang, Wei, Wang, Denong, Yamada, Masao, Wang, LaiXi. Chemoenzymatic Synthesis and Lectin Array Characterization of a Class of N-Glycan Clusters. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2009, 131(49): 17963-17971, https://www.webofscience.com/wos/woscc/full-record/WOS:000273028800048.
[65] Huang, Wei, Li, Cishan, Li, Bing, Umekawa, Midori, Yamamoto, Kenji, Zhang, Xinyu, Wang, LaiXi. Glycosynthases Enable a Highly Efficient Chemoenzymatic Synthesis of N-Glycoproteins Carrying Intact Natural N-Glycans. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2009, 131(6): 2214-2223, https://www.webofscience.com/wos/woscc/full-record/WOS:000264792200051.
[66] Li, Cishan, Huang, Wei, Wang, LaiXi. Chemoenzymatic synthesis of N-linked neoglycoproteins through a chitinase-catalyzed transglycosylation. BIOORGANIC & MEDICINAL CHEMISTRY[J]. 2008, 16(18): 8366-8372, http://dx.doi.org/10.1016/j.bmc.2008.08.042.
[67] Huang, Wei, Ochiai, Hirofumi, Zhang, Xinyu, Wang, LaiXi. Introducing N-glycans into natural products through a chemoenzymatic approach. CARBOHYDRATE RESEARCH[J]. 2008, 343(17): 2903-2913, http://dx.doi.org/10.1016/j.carres.2008.08.033.
[68] Huang Yu. Mutants of Mucor hiemalis endo-beta-N-acetylglucosaminidases show enhanced transglycosylation and glycosynthase-like activities.. J. Biol. Chem.. 2008, [69] Ochiai, Hirofumi, Huang, Wei, Wang, LaiXi. Expeditious chemoenzymatic synthesis of homogeneous N-glycoproteins carrying defined oligosaccharide ligands. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2008, 130(41): 13790-13803, https://www.webofscience.com/wos/woscc/full-record/WOS:000259924000050.
[70] Wei, Yadong, Li, Cishan, Huang, Wei, Li, Bing, Strome, Scott, Wang, LaiXi. Glycoengineering of human IgG1-Fc through combined yeast expression and in vitro chemoenzymatic glycosylation. BIOCHEMISTRY[J]. 2008, 47(39): 10294-10304, https://www.webofscience.com/wos/woscc/full-record/WOS:000259450400008.
[71] Zhang, Liuyin, Huang, Wei, Tanimura, Akihiko, Morita, Takao, Harihar, Sitaram, DeWald, Daryll B, Prestwich, Glenn D. Synthesis and biological activity of metabolically stabilized cyclopentyl trisphosphate analogues of D-myo-Ins(1,4,5)P-3. CHEMMEDCHEM[J]. 2007, 2(9): 1281-1289, https://www.webofscience.com/wos/woscc/full-record/WOS:000249500800006.
[72] Huang, Wei, Zhang, Honglu, Davrazou, Foteini, Kutateladze, Tatiana G, Shi, Xiaobing, Gozani, Or, Prestwich, Glenn D. Stabilized phosphatidylinositol-5-phosphate analogues as ligands for the nuclear protein ING2: Chemistry, biology, and molecular modeling. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2007, 129(20): 6498-6506, https://www.webofscience.com/wos/woscc/full-record/WOS:000246535300040.
[73] Zhao, Liqin, Huang, Wei, Liu, Hongying, Wang, Lili, Zhong, Wu, Xiao, Junhai, Hu, Yuandong, Li, Song. FK506-binding protein ligands: structure-based design, synthesis, and neurotrophic/neuroprotective properties of substituted 5,5-dimethyl-2-(4-thiazolidine) carboxylates. JOURNAL OF MEDICINAL CHEMISTRY[J]. 2006, 49(14): 4059-4071, https://www.webofscience.com/wos/woscc/full-record/WOS:000238805800011.
[74] Huang, W, Zhang, X, Liu, H, Shen, JH, Jiang, HL. New selective O-debenzylation of phenol with Mg/MeOH. TETRAHEDRON LETTERS[J]. 2005, 46(35): 5965-5967, http://www.corc.org.cn/handle/1471x/2377358.
[75] Huang Yu. Microwave-Assisted Synthesis of 2-Amino-thiophene-3-carboxylic Derivatives under Solvent-Free Condition.. Synth. Commun.. 2005,