基本信息
庄秀丽 女 长春应用化学研究所
电子邮件:zhuangxl@ciac.jl.cn
通信地址:吉林省长春市人民大街5625号
邮政编码:130022

招生信息

   
招生专业
070305-高分子化学与物理
招生方向
生物医用高分子材料

教育背景

2008-04--2010-09 日本早稻田大学 博士研究生/工学博士
1991-09--1994-06 中国科学院长春应用化学研究所 硕士研究生/理学硕士

工作经历

   
工作简历
2011-12--2013-06 中国科学院长春应用化学研究所 研究员
1994-06--2011-12 中国科学院长春应用化学研究所 副研究员

专利与奖励

   
奖励信息
(1) 聚合物纳米水凝胶及其制备方法,一等奖,省级,2013
(2) 可降解医用高分子材料的基础研究及应用探索,一等奖,省级,2011
(3) 聚乳酸新材料关键技术研发与产业化应用,一等奖,部委级,2011
(4) 新型生物可降解高分子材料的合成与应用探索,一等奖,省级,2007
(5) 科技成果转化,二等奖,院级级,2001
(6) 新型均混配稀土金属有机化合物的合成及其结构,二等奖,院级级,1997
专利成果
(1) 聚氨基酸接枝共聚物及其制备方法,发明,2011,第1作者,专利号:CN201110023705.1
(2) 一种聚合物微凝胶及其制备方法,发明,2010,第1作者,专利号:CN201010130890.X
(3) 聚氨基酸嵌段共聚物及其制备方法,发明,2011,第1作者,专利号:CN201110343619.9
(4) 胰岛素载药微球及其制备方法,发明,2011,第4作者,专利号:CN201110368851.8
(5) 聚乳酸共聚物及其制备方法、改性聚乳酸,发明,2013,第4作者,专利号:CN201310042190.9
(6) 一种共聚物水凝胶及其制备方法,发明,2012,第3作者,专利号:CN201210438767.3
(7) 聚(N-异丙基丙烯酰胺)-聚(丙烯酸或丙烯酸衍生物)共聚物及其制备方法,发明,2012,第3作者,专利号:CN201210438766.9
(8) 一种聚氨酯嵌段共聚物、其制备方法及其纳米水凝胶的制备方法,发明,2012,第3作者,专利号:CN201210401496.4
(9) 一种聚醚无规共聚物及其制备方法,发明,2012,第3作者,专利号:CN201210363924.9
(10) 一种聚乳酸嵌段共聚物及其制备方法,发明,2012,第4作者,专利号:CN201210361613.9
(11) 一种脂肪族聚酯-聚氨基酸嵌段共聚物及其制备方法以及一种水凝胶及其制备方法,发明,2012,第4作者,专利号:CN201210341827.X
(12) 一种嵌段共聚物、其制备方法及水凝胶,发明,2012,第4作者,专利号:CN201210142245.9
(13) 人体颅骨修复支架及其制备方法,发明,2011,第3作者,专利号:CN201110274335.9
(14) 氯乙醇功能化聚(L-谷氨酸)均聚与无规共聚物及制法和应用,发明,2009,第1作者,专利号:CN200910218013.5
(15) 聚氨基酸的制备方法及聚氨基酸纳米水凝胶,发明,2011,第1作者,专利号:CN201110023774.2
(16) 聚(γ-丙炔基-L-谷氨酸酯)嵌段共聚物、其制备方法及水凝胶,发明,2011,第3作者,专利号:CN201110023965.9
(17) 聚乳酸嵌段共聚物及其制备方法、改性聚乳酸,发明,2013,第4作者,专利号:CN201310057243.4
(18) 一种聚氨基酸/壳聚糖复合材料及其制备方法,发明,2012,第5作者,专利号:CN201210500684.2
(19) 前后交叉韧带修复用可吸收界面螺钉及其制备方法,发明,2012,第5作者,专利号:CN201210476059.9
(20) 一种树枝状大分子聚(酰胺-胺)接枝的葡聚糖及其制备方法,发明,2012,第5作者,专利号:CN201210428081.6
(21) 一种阳离子类脂质体及其制备方法,发明,2012,第5作者,专利号:CN201210428233.2
(22) 顺铂配合物及其制备方法,发明,2012,第5作者,专利号:CN201210382696.X
(23) 一种聚醚嵌段共聚物及其制备方法,发明,2012,第3作者,专利号:CN201210363911.1
(24) 一种聚乳酸嵌段共聚物的制备方法,发明,2012,第3作者,专利号:CN201210313021.X
(25) 一种嵌段共聚物及其制备方法,发明,2012,第4作者,专利号:CN201210142268.X
(26) 一种聚乳酸组合物及聚乳酸制品,发明,2012,第5作者,专利号:CN201210109025.6
(27) 可吸收血管支架,发明,2011,第2作者,专利号:CN201110212448.6
(28) 聚(L-谷氨酸)均聚物、无规共聚物、接枝共聚物及其制备方法,发明,2010,第1作者,专利号:CN201010563665.5
(29) 高分子阿霉素键合药及其制备方法,发明,2011,第1作者,专利号:CN201110343633.9
(30) 聚合物纳米水凝胶及其制备方法,发明,2010,第1作者,专利号:CN201010561226.0
(31) 一种功能化聚酯及其制备方法,发明,2010,第1作者,专利号:CN201010130905.2
(32) 一种聚(L-谷氨酸)/聚丙烯酸水凝胶及其制备方法,发明,2010,第1作者,专利号:CN201010130914.1
(33) 抗肿瘤前药及其制备方法,发明,2011,第5作者,专利号:CN201110149748.4
(34) 聚氨基酸嵌段共聚物的制备方法及聚氨基酸嵌段共聚物水凝胶,发明,2013,第3作者,专利号:CN201210492369.X
(35) 一种聚乳酸嵌段共聚物及改性聚乳酸的制备方法,发明,2012,第5作者,专利号:CN201210377804.4
(36) 嵌段共聚物及其制备方法,发明,2011,第5作者,专利号:CN201110325770.X
(37) 聚合物纳米水凝胶及其制备方法,发明,2010,第1作者,专利号:CN201010563357.2
(38) 阿霉素键合药及其制备方法,发明,2012,第1作者,专利号:CN201210512758.4
(39) 聚(γ-炔丙基-L-谷氨酸酯)-聚氨基酸嵌段共聚物、功能化嵌段共聚物及制备方法,发明,2012,第1作者,专利号:CN201210424521.0
(40) 聚(γ-寡聚乙二醇单甲醚-L-谷氨酸酯)-聚氨基酸两嵌段共聚物及其制备方法,发明,2013,第3作者,专利号:CN201210571599.5
(41) 一种嵌段共聚物、其制备方法及电活性水凝胶,申请(专利)号,发明,2012,第4作者,专利号:CN201210548377.1
(42) 一种嵌段共聚物、其制备方法及水凝胶,发明,2012,第4作者,专利号:CN201210512774.3
(43) 聚氨基酸嵌段共聚物、其制备方法及温度敏感型水凝胶,发明,2013,第3作者,专利号:CN201210496188.4
(44) 一种聚醚均聚物及其制备方法,发明,2012,第4作者,专利号:CN201210366403.9
(45) 超支化聚氨酯的制备方法与改性聚乳酸树脂及其制备方法,发明,2012,第5作者,专利号:CN201210039908.4
(46) 可吸收骨折内固定件,发明,2011,第2作者,专利号:CN201110212366.1

出版信息

   
发表论文
(1) Nano-hydroxyapatite surfaces grafted with electroactive aniline tetramers for bone-tissue engineering,Macromolecular Bioscience,2013,第3作者
(2) Biocompatible reduction-responsive polypeptide micelles as nanocarriers for enhanced chemotherapy efficacy in vitro,Journal of Materials Chemistry B,2013,通讯作者
(3) Efficacious hepatoma-targeted nanomedicine self-assembled from galactopeptide and doxorubicin driven by two-stage physical interactions,Journal of Controlled Release,2013,通讯作者
(4) Thermo-responsive “hairy-rod” polypeptides for smart antitumor drug delivery,Polymer Chemistry ,2013,第5作者
(5) Biodegradable pH-responsive polyacrylic acid derivative hydrogels with tunable swelling behavior for oral delivery of insulin,Polymer ,2013,第4作者
(6) Self-assemblies of pH-activatable PEGylated multi-arm poly(lactic acid-co-glycolic acid)-doxorubicin prodrugs with improved long-term antitumor efficacies,Macromolecular Bioscience,2013,第3作者
(7) Enhanced endocytosis of acid-sensitive doxorubicin derivatives with intelligent nanogel for improved security and efficacy,Biomaterials Science ,2013,通讯作者
(8) Disulfide crosslinked PEGylated starch micelles as efficient intracellular drug deliv ery platforms,Soft Matter ,2013,通讯作者
(9) Facile construction of functional biosurface via SI-ATRP and “click glycosylation”,Colloids and Surfaces B: Biointerfaces,2012,第5作者
(10) Photo-cross-linked biodegradable thermo- and pH-responsive hydrogels for controlled drug release,Journal of Applied Polymer Science ,2012,通讯作者
(11) Direct formation of cationic polypeptide vesicle as potential carrier for drug and gene,Materials Letters,2012,第3作者
(12) Decisive role of hydrophobic side groups of polypeptides in thermosensitive gelation,Biomacromolecules ,2012,第5作者
(13) Research of chemiluminescent assay of alkaline phosphatase based on microplate,Chinese Journal of Analytical Chemistry ,2012,第4作者
(14) Synthesis and characterization of novel biodegradable and electroactive hydrogel based on aniline oligomer and gelatin,Macromolecular Bioscience,2012,第3作者
(15) pH-responsive drug delivery systems based on clickable poly(L-glutamic acid)-grafted comb copolymers,Macromolecular Research,2012,第5作者
(16) In vitro evaluation of anticancer nanomedicines based on doxorubicin and amphiphilic Y-shaped copolymers,International Journal of Nanomedicine,2012,第5作者
(17) Stimuli-sensitive synthetic polypeptide-based materials for drug and gene delivery,Advanced Healthcare Materials ,2012,第2作者
(18) Intracellular microenvironment responsive PEGylated polypeptide nanogels with ionizable cores for efficient doxorubicin loading and triggered release,Journal of Materials Chemistry,2012,通讯作者
(19) Biodegradable thermo-sensitive hydrogels for controlled delivery of parathyroid hormone related peptide,Acta Polymerica Sinica,2012,第4作者
(20) Synthesis and characterization of biodegradable pH-sensitive poly(acrylic acid) hydrogels crosslinked by 2-hydroxyethyl methacrylate modified poly(L-glutamic acid),Materials Letters,2012,第4作者
(21) Thermo- and pH-responsive microgels for controlled release of insulin,Polymer International ,2012,通讯作者
(22) Biodegradable synthetic polymers: Preparation, functionalization and biomedical application,Progress in Polymer Science ,2012,第3作者
(23) Biodegradable pH-dependent thermo-sensitive hydrogels for oral insulin delivery,Macromolecular Chemistry and Physics ,2012,通讯作者
(24) Synthesis and characterization of tumor-acidity-sensitive poly (L-lysine) -doxorubicin conjugates,Chemical Journal of Chinese Universities-Chinese,2012,通讯作者
(25) Synthesis of amphiphilic alternating polyesters with oligo(ethylene glycol) side chains and potential use for sustained release drug delivery,Biomacromolecules,2011,通讯作者
(26) Preparation and characterization of biodegradable and electroactive polymer blend materials based on mPEG/tetraaniline and PLLA,Macromolecular Bioscience,2011,第3作者
(27) Crystallization behavior of asymmetric PLLA/PDLA blends,Journal of Physical Chemistry B,2011,第3作者
(28) Highly efficient “grafting from” an α-helical polypeptide backbone by atom transfer radical polymerization,Macromolecular Bioscience,2011,第4作者
(29) Synthesis of temperature and pH-responsive crosslinked micelles from polypeptide-based graft copolymer,Journal of Colloid and Interface Science,2011,通讯作者
(30) Facile synthesis of thermo- and pH-responsive biodegradable microgels,Colloid and Polymer Science,2011,通讯作者
(31) Facile preparation of a cationic poly(amino acid) vesicle for potential drug and gene co-delivery,Nanotechnology,2011,通讯作者
(32) pH and dual redox responsive nanogel based on poly(L-glutamic acid) as potential intracellular drug carrier,Journal of Controlled Release,2011,第5作者
(33) The crystallization behavior of poly(ethylene glycol)-poly(ε-caprolactone) diblock copolymers with asymmetric block compositions,Journal of Polymer Research,2011,第3作者
(34) Preparation and characterization of a new copolymer poly (L-glutamic acid)-block-poly(lactic-co-glycolic acid),Journal of Controlled Release ,2011,第3作者
(35) Versatile synthesis of temperature-sensitive polypeptides by click grafting of oligo(ethylene glycol),Polymer Chemistry,2011,第5作者
(36) Polymerization of lactic O-carboxylic anhydride using organometallic catalysts,Chinese Journal of Polymer Science,2011,第1作者
(37) Preparation of photo-cross-linked pH-responsive polypeptide nanogels as potential carriers for controlled drug delivery,Journal of Materials Chemistry ,2011,第2作者
(38) Synthesis and swelling behavior of degradable pH-sensitive hydrogels composed of poly(L-glutamic acid) and poly(acrylic acid),Acta Polymerica Sinica,2011,第3作者
(39) Synthesis, characterization and self-assembly of PEG-aniline tetramer block copolymer,Chemical Journal of Chinese Universities-Chinese ,2011,第2作者
(40) One-step preparation of reduction-responsive poly(ethylene glycol)-poly (amino acid)s nanogels as efficient intracellular drug delivery platforms,Polymer Chemistry ,2011,通讯作者
(41) Synthesis and electrochemistry of schiff base cobalt(III) complexes and their catalytic activity for copolymerization of epoxide and carbon dioxide,Macromolecular Chemistry and Physics,2010,第1作者
(42) Polylactic acid (PLA): Research, development and industrialization,Biotechnology Journal,2010,第2作者
(43) Synthesis of amphiphilic block copolymers bearing stable nitroxyl radicals,Journal of Polymer Science, Part A: Polymer Chemistry,2010,第1作者
(44) pH-dependent self-assembly of amphiphilic poly(L-glutamic acid)-block-poly(lactic-co-glycolic acid) copolymers,Polymer,2010,第3作者
(45) Biodegradable and electroactive TEMPO-substituted acrylamide/lactide copolymers,Macromolecular Bioscience,2010,第1作者
(46) Synthesis and characterization of electroactive graft copolymer of poly(L-glutamic acid)-g-aniline tetramer,Acta Polymerica Sinica,2010,第2作者
(47) Compatibilizing effect of starch-grafted-poly(L-lactide) on the poly(ε-caprolactone)/starch composites,Journal of Applied Polymer Science,2010,第3作者

科研活动

   
科研项目
(1) 多功能聚氨基酸纳米水凝胶的制备与药物控制释放应用,主持,国家级,2013-01--2016-12
(2) 高性能聚乳酸薄膜专用树脂合成与应用开发,主持,市地级,2011-11--2013-12
(3) 颅骨缺损自修复可吸收支架的研究,主持,省级,2011-01--2013-01
参与会议
(1) Polypeptide nanogels for controlled drug delivery,2012-05,Xiuli Zhuang, Jianxun Ding, Chunsheng Xiao, Chaoliang He, Xuesi Chen
(2) Biodegradable pH-responsive poly(L-glutamic acid)/poly(acrylic acid) hybrid hydrogels,2011-11,Xiuli Zhuang
(3) Synthesis and swelling behaviors of biodegradable poly(L-glutamic acid) and poly(acrylic acid) hydrogels,2011-05,Xiuli Zhuang
(4) Synthesis of block and graft copolymers of TEMPO-bearing acrylamides and lactates for biomedical application,2010-05,Xiuli Zhuang, Kenichi Oyaizu, Chunsheng Xiao, Natsuru Chikushi, Xuesi Chen, Hiroyuki Nishide
(5) Synthesis of amphiphilc with stable nitroxyl radicals,2010-03,Xiuli Zhuang, Chunsheng Xiao, Kenichi Oyaizu, Xuesi Chen, Hiroyuki Nishide