General

Current Research: 

Biomedical Materials: Ceramics, glasses, glass-ceramics and composites for medical and dental applications; bioactive materials; scaffolds for musculoskeletal tissue engineering; ceramics and glasses for drug delivery and wound healing

Advanced Ceramics: Processing, sintering, and microstructure control of ceramics


Research Areas

Bone Tissue Engineering

Bioactive Glass

Osteoimmunology

Wound dressing

Marine biomaterials


Education

02/2018-now Shenzhen Institutes of Advanced Technology, CAS Associate professor

07/2015-01/2018 Shenzhen Institutes of Advanced Technology, CAS Research associate

09/2010-03/2015 Tongji University Materials Science Ph. D

09/2007-07/2010 Huaqiao University Materials processing engineering M.S

09/2003 - 07/2007 Huaqiao University Materials Science and Engineering B.S

Experience

   
Work Experience

Associate research fellow in Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences

Senior engineer of Medical Devices
Teaching Experience
Biomaterials

Tissue Engineering

Sintering and Microstructure Control

Organic Additives in Ceramic Processing

Thermal Processes in Ceramics

Publications


Papers

  1. Xu Cui#, Yadong Zhang#, Jianyun Wang#, Chengcheng HuangYudong Wang, Hongsheng YangWenlong Liu, Ting Wang, Deping Wang, Guocheng Wang, Changshun Ruan, Dafu Chen*, William W. Lu, Wenhai Huang, Mohamed N. Rahaman*, Haobo Pan*. Strontium Modulates Osteogenic Activity of Bone Cement Composed of Bioactive Borosilicate Glass Particles by Activating Wnt/β-catenin signaling pathway. Bioactive Materials, 2020, 5: 334-347.
  2. Meng Zhang, Jukka P. Matinlinna, James K. H. Tsoi, Wenlong Liu, Xu Cui, William W. Lu, Haobo Pan*. Recent developments in biomaterials for long-bone segmental defect reconstruction: A narrative overview. Journal of Orthopaedic Translation, 2019, accepted.
  3. Fei Gao, Ziyang Xu, Qingfei Liang, Haofei Li, Liuqi Peng, Mingming Wu, Xiaoli Zhao, Xu Cui, Changshun Ruan,* Wenguang Liu*. Osteochondral Regeneration with 3D‐Printed Biodegradable High‐Strength Supramolecular Polymer Reinforced-Gelatin Hydrogel Scaffolds. Advanced Science, 2019, 6 (15): 1900867.
  4. Wenlong Liu, Xiuli Dan, William W. Lu, Xiaoli Zhao, Changshun Ruan, Ting Wang, Xu Cui, Xinyun Zhai, Yufei Ma, Deping Wang, Wenhai Huang, Haobo Pan*. Spatial Distribution of Biomaterial Microenvironment pH and Its Modulatory Effect on Osteoclasts at the Early Stage of Bone Defect Regeneration. ACS Applied Materials & Interfaces, 2019, 11(9): 9557-9572.
  5. Tiancheng Lv, Wei Liang, Li Li, Xu Cui, Xiaomou Wei, Haobo Pan, Bing Li*. Novel calcitonin gene‐related peptide/chitosan‐strontium‐calcium phosphate cement: Enhanced proliferation of human umbilical vein endothelial cells in vitro. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2019, 107(1): 19-28.
  6. Xu Cui, Chengcheng Huang, Meng Zhang, Changshun Ruan*, Songlin Peng, Li Li, Wenlong Liu, Ting Wang, Bing Li, Wenhai Huang, Mohamed N. Rahaman, William W Lu, Haobo Pan*. Enhanced osteointegration of poly(methylmethacrylate) bone cements by incorporating strontium-containing borate bioactive glass. Journal of the Royal Society Interface, 2017, 14(131): 20161057.
  7. Xu Cui, Wenhai Huang, Yadong Zhang*, Chengcheng Huang, Zunxiong Yu,Lei Wang, Wenlong Liu, Ting Wang, Jie Zhou, Hui Wang, Nai Zhou, Deping Wang, Haobo Pan*, Mohamed N. Rahaman*. Evaluation of an injectable bioactive borate glass cement to heal bone defects in a rabbit femoral condyle model. Materials Science and Engineering: C, 2017, 73, 585–595.
  8. Li Li, Xiaozhong Peng, Yongbao Qin, Renchong Wang, Jingli Tang, Xu Cui, Ting Wang, Wenlong Liu, Haobo Pan*, Bing Lib*. Acceleration of bone regeneration by activating Wnt/β-catenin signalling pathway via lithium released from lithium chloride/calcium phosphate cement in osteoporosis. Scientific Reports, 2017, 7, 45204.
  9. Guilin Luo, Yufei Ma, Xu Cui, Lixin Jiang, Mingming Wu, Yang Hu, Yanfeng Luo, Haobo Pan, Changshun Ruan*. 13-93 bioactive glass/alginate composite scaffolds 3D printed under mild conditions for bone regeneration. RSC Advances, 2017, 7, 11880-11889.
  10. Li Li, Renchong Wang, Baichuan Li, Wei Liang, Haobo Pan, Xu Cui, Jingli Tang, Bing Li* . Lithium doped calcium phosphate cement maintains physical mechanical properties and promotes osteoblast proliferation and differentiation. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2016.03.20.
  11. Wei Liang, Zhongfei Tang, Xiaomou Wei, Bing Li*, Li Li, Xu Cui, Haobo Pan. Enhanced proliferation and differentiation effects of a CGRP- and Sr-enriched calcium phosphate cement on bone mesenchymal stem cells. Journal of Applied Biomaterials & Functional Materials, 2016, 14(4), 431-440.
  12. Xu Cui#, Yadong Zhang#, Shichang Zhao, Hui Wang, Haobo Pan*, Mohamed N. Rahaman*, Wenhai Huang*, Changqing Zhang. An injectable borate bioactive glass cement for bone repair: Preparation, bioactivity and setting mechanism. Journal of Non-Crystalline Solids, 2016, 432, 150-157.
  13. Hui WangShichang Zhao,  Jie ZhouKaiping ZhuXu Cui,   Wenhai Huang,   Mohamed N. Rahaman*,  Changqing Zhang*, Deping Wang*. Biocompatibility and osteogenic capacity of borosilicate bioactive glass scaffolds loaded with Fe3O4 magnetic nanoparticles. Journal of Materials Chemistry B, 2015, 21, 4377-4387.
  14. Hui Wang,  Shichang ZhaoWei Xiao, Xu CuiWenhai HuangMohamed N. Rahaman*, Changqing Zhang*, Deping Wang*. Three-dimensional zinc incorporated borosilicate bioactive glass scaffolds for rodent critical-sized calvarial defects repair and regeneration. Colloids and Surfaces B: Biointerfaces, 130, 149-156, 2015.
  15. Hui Wang, Shichang Zhao, Xu Cui, Yangyi Pan, Wenhai Huang, Song Ye, Shihua Luo, Mohamed N. Rahaman, Changqing Zhang, Deping Wang. Evaluation of three-dimensional silver-doped borate bioactive glass scaffolds for bone repair: Biodegradability, biocompatibility, and antibacterial activity. Journal of Materials Research, 2015, 30(18), 2722-2735.
  16. Yadong Zhang#, Xu Cui#, Shichang Zhao, Hui Wang, Mohamed N. Rahaman, Wenhai Huang, Changqing Zhang. Evaluation of novel injectable strontium-containing borate bioactive glass cement with desirable workability and enhanced osseointegration properties in a critical-size rabbit femoral condyle defect model. ACS Applied Materials & Interfaces, 2015, 7(4), 2393-2403. (Joint first authors)
  17. Xu Cui, Cunju Zhao, Yifei GuLe LiHui WangWenhai Huang*, Nai Zhou, Deping Wang, Yi Zhu, Jun Xu, Shihua LuoChangqing Zhang, Mohamed N. Rahaman*. A novel injectable borate bioactive glass cement for local delivery of vancomycin to cure osteomyelitis and regenerate bone. Journal of Materials Science: Materials in Medicine, 2014, 25(3), 733-745.
  18. Hao Ding, Cun-Ju Zhao, Xu Cui, Yi-Fei Gu,Wei-Tao Jia, Mohamed N. Rahaman, Yang Wang, Wen-Hai Huang*,Chang-Qing Zhang*. A Novel Injectable Borate Bioactive Glass Cement as an Antibiotic Delivery Vehicle for Treating Osteomyelitis. Plos one, 2014, 9(10), 1-9.
  19. Xu CuiYifei GuLe LiHui WangZhongping XieShihua LuoNai ZhouWenhai Huang*, Mohamed N. RahamanIn vitro bioactivity, cytocompatibility, and antibiotic release profile of gentamicin sulfate-loaded borate bioactive glass/chitosan composites. Journal of Materials Science: Materials in Medicine, 2013, 24(10), 2391-2403.
  20. Zongping XieXu CuiCunju ZhaoWenhai HuangJianqiang Wang,  Changqing Zhang*. Gentamicin-Loaded Borate Bioactive Glass Eradicates Osteomyelitis Due to Escherichia coli in a Rabbit Model. Antimicrob. Agents Chemother, 2013, 57(7), 3293-3298.


Students

已指导学生

卢丹萍  硕士研究生  085204-材料工程  

叶丰明  硕士研究生  085204-材料工程  

现指导学生

胡成深  硕士研究生  085204-材料工程  

纪佳雯  硕士研究生  085600-材料与化工  

张旭  硕士研究生  086000-生物与医药