基本信息

祝心舟  男  博导  中国科学院深圳先进技术研究院
电子邮件: xz.zhu@siat.ac.cn
通信地址: 广东省深圳市南山区西丽大学城学苑大道1068号
邮政编码:518055

招生信息

   
招生方向
脑缺血的神经保护与修复,胶质瘤的发生机制

教育背景

2012-03--2016-03   瑞士巴塞尔大学理学院   哲学博士
2009-09--2011-06   瑞士苏黎世联邦理工大学生物系   理学硕士
2005-09--2009-06   中山大学生命科学学院   理学学士

工作经历

   
工作简历
2020-09~现在, 中国科学院深圳先进技术研究院脑所, 副研究员
2019-08~2020-06,德国雷根斯堡大学医院, 助理研究员
2016-04~2019-07,瑞士巴塞尔大学儿童医院, 博士后
2011-07~2012-02,瑞士巴塞尔大学儿童医院, 研究助理

出版信息

   
发表论文
[1] Zhao, Junyi, Liu, Siyu, Yan, Jingyi, Zhu, Xinzhou. The Impact of Gut Microbiota on Post-Stroke Management. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY[J]. 2021, 11: http://dx.doi.org/10.3389/fcimb.2021.724376.
[2] Steffen, Philipp A, Altmutter, Christina, Dworschak, Eva, Junttila, Sini, Gyenesei, Attila, Zhu, Xinzhou, Kockmann, Tobias, Ringrose, Leonie. The Trithorax group protein ASH1 requires a combination of BAH domain and AT hooks, but not the SET domain, for mitotic chromatin binding and survival. CHROMOSOMA[J]. 2021, 130(2-3): 215-234, http://dx.doi.org/10.1007/s00412-021-00762-z.
[3] Xinzhou Zhu, Jingyi Yan, Catherine Bregere, Andrea Zelmer, Tessa Goerne, Josef P Kapfhammer, Raphael Guzman, Sven Wellmann. RBM3 promotes neurogenesis in a niche-dependent manner via IMP2-IGF2 signaling pathway after hypoxic-ischemic brain injury. Nature Communications[J]. 2019, 10(1): 1-14, http://dx.doi.org/10.1038/s41467-019-11870-x.
[4] Yan, Jingyi, Goerne, Tessa, Zelmer, Andrea, Guzman, Raphael, Kapfhammer, Josef P, Wellmann, Sven, Zhu, Xinzhou. The RNA-Binding Protein RBM3 Promotes Neural Stem Cell (NSC) Proliferation Under Hypoxia. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY[J]. 2019, 7: https://www.webofscience.com/wos/woscc/full-record/WOS:000514083700001.
[5] Xinzhou Zhu, Andrea Zelmer, Sven Wellmann. Visualization of Protein-protein Interaction in Nuclear and Cytoplasmic Fractions by Co-immunoprecipitation and In Situ Proximity Ligation Assay. Journal of Visualized Experiments : JoVE. 2017, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352272/.
[6] Zhu, Xinzhou, Buhrer, Christoph, Wellmann, Sven. Cold-inducible proteins CIRP and RBM3, a unique couple with activities far beyond the cold. CELLULAR AND MOLECULAR LIFE SCIENCESnull. 2016, 73(20): 3839-3859, https://www.webofscience.com/wos/woscc/full-record/WOS:000383613900007.
[7] Zhu, Xinzhou, Zelmer, Andrea, Kapfhammer, Josef P, Wellmann, Sven. Cold-inducible RBM3 inhibits PERK phosphorylation through cooperation with NF90 to protect cells from endoplasmic reticulum stress. FASEB JOURNAL[J]. 2016, 30(2): 624-634, https://www.webofscience.com/wos/woscc/full-record/WOS:000369391900015.
[8] Sophorn Chip, Xinzhou Zhu, Josef P Kapfhammer. The Analysis of Neurovascular Remodeling in Entorhino-hippocampal Organotypic Slice Cultures. Journal of Visualized Experiments : JoVE. 2014, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353386/.
[9] Kockmann, Tobias, Gerstung, Moritz, Schlumpf, Tommy, Zhu Xhinzhou, Hess, Daniel, Beerenwinkel, Niko, Beisel, Christian, Paro, Renato. The BET protein FSH functionally interacts with ASH1 to orchestrate global gene activity in Drosophila. GENOME BIOLOGY[J]. 2013, 14(2): R18-R18, https://www.webofscience.com/wos/woscc/full-record/WOS:000322388800008.

科研活动

   
科研项目
( 1 ) 中国科学院深圳先进技术研究院创新项目-新引进人才启动基金, 主持, 部委级, 2021-03--2022-12
( 2 ) 新引进团队科研启动费——冷诱导蛋白RBM3对缺氧缺血性脑损伤中神经炎症反应的作用研究, 主持, 省级, 2020-01--2023-12
参与会议
(1)Cold-inducible RBM3 promotes neurogenesis after cerebral hypoxic-ischemic injury in adult mice   2018-07-07
(2)Cold-inducible RBM3 promotes neurogenesis after brain hypoxic-ischemia/reperfusion(HI/R) injury   2017-10-31
(3)Cold-inducible RBM3 promotes the proliferation of neural stem/progenitor cell (NSPC) and neurogenesis through oncofetal protein IMP2   2016-11-12
(4)Cold-inducible RNA binding protein RBM3 prevents ER stress-induced apoptosis   2015-09-16
(5)Cold-inducible RNA binding protein 3 (RBM3) promotes neuroprotection   2014-11-15