基本信息
陈敬钦  男    中国科学院深圳先进技术研究院
电子邮件: jq.chen@siat.ac.cn
通信地址: 深圳市南山区西丽大学城学苑大道1068号
邮政编码:

招生信息

   
招生专业
083100-生物医学工程
071010-生物化学与分子生物学
070305-高分子化学与物理
招生方向
分子探针合成及其生物医学应用
动物模型构建及其诊疗研究
卟啉分子探针开发

教育背景

2017-09--2020-07   中国科学院大学   博士研究生
2011-09--2014-07   华南师范大学   硕士研究生

工作经历

   
工作简历
2021-01~现在, 中国科学院深圳先进技术研究院, 副研究员
2019-01~2020-01,美国德克萨斯大学奥斯汀分校, 访问学者

专利与奖励

   
奖励信息
(1) 深圳市海外高层次人才, 市地级, 2020
(2) 中国科学院大学“三好学生”, 研究所(学校), 2019
(3) 深圳先进院医工所所长创新基金“学术新星奖”, 研究所(学校), 2018
(4) 深圳先进院医工所所长创新基金“学术论文奖”, 研究所(学校), 2016
(5) 中科院深圳先进院 “优秀员工”奖, 研究所(学校), 2016
专利成果
[1] 陈敬钦, 刘成波, 宋亮, 李学深, 方驰华. 一种用于光声成像和光热治疗的分子探针的制备方法. CN: CN107737349B, 2021-02-19.
[2] 朱颖, 宋亮, 盛宗海, 刘成波, 陈敬钦. 二硫化钼-吲哚菁绿纳米复合颗粒及其制备方法和应用. CN: CN107243082B, 2020-08-04.
[3] 刘成波, 宋亮, 邢沐悦, 陈敬钦. 一种光声探头及光声成像系统. CN: CN106691390B, 2020-04-14.
[4] 陈敬钦, 刘筱阳, 刘成波, 严慧翔, 方驰华, 宋亮. 一种基于二硒化钼纳米片的光声成像分子探针的制备方法. 中国: CN108066778A, 2018.05.25.
[5] 宋亮, 宋伟, 刘成波, 陈敬钦, 曾光. 一种暗场照明声学分辨率光声显微镜. 中国: CN105548022B, 2018-08-10.
[6] 陈敬钦, 宋亮, 刘成波, 林日强. 一种装载紫杉醇的纳米药物复合体及其制备方法. 中国: CN104758240B, 2017-12-19.
[7] 陈敬钦, 刘成波, 盛宗海, 宋亮. 一种二硫化钼纳米片的剥离制备方法及二硫化钼纳米片的应用. 中国: CN106563130A, 2017-04-19.
[8] 宋亮, 宋伟, 刘成波, 陈敬钦, 曾光. 一种暗场照明声学分辨率光声显微装置. 中国: CN105662339A, 2016-06-15.
[9] 陈敬钦, 宋亮, 刘成波, 曾光, 王慧娜, 闫盟. 一种光声成像用纳米复合造影剂及其制备方法. 中国: CN104548139A, 2015-04-29.

出版信息

   
五篇代表作(一作/共同一作)
[1] Chen, Jingqin, Sedgwick, Adam C, Sen, Sajal, Ren, Yaguang, Sun, Qinchao, Chau, Calvin, Arambula, Jonathan F, Sarma, Tridib, Song, Liang, Sessler, Jonathan L, Liu, Chengbo. Expanded porphyrins: functional photoacoustic imaging agents that operate in the NIR-II region. CHEMICAL SCIENCE[J]. 2021, 12(29): 9916-9921, http://dx.doi.org/10.1039/d1sc01591e.
[2] Hu, Yaxin, Xue, Shan, Long, Ting, Lyu, Peizhao, Zhang, Xinyu, Chen, Jingqin, Chen, Siping, Liu, Chengbo, Chen, Xin. Opto-acoustic synergistic irradiation for vaporization of natural melanin-cored nanodroplets at safe energy levels and efficient sono-chemo-photothermal cancer therapy. THERANOSTICS[J]. 2020, 10(23): 10448-10465, https://www.webofscience.com/wos/woscc/full-record/WOS:000566786700006.
[3] 陈敬钦. 光声分子影像技术在疾病靶向诊疗中的应用研究. 2020, [4] Chen, Jingqin, Qi, Ji, Chen, Chao, Chen, Jianhai, Liu, Liangjian, Gao, Rongkang, Zhang, Tiantian, Song, Liang, Ding, Dan, Zhang, Peng, Liu, Chengbo. Tocilizumab-Conjugated Polymer Nanoparticles for NIR-II Photoacoustic-Imaging-Guided Therapy of Rheumatoid Arthritis. ADVANCED MATERIALS[J]. 2020, 32(37): https://www.webofscience.com/wos/woscc/full-record/WOS:000554482800001.
[5] Ren, Yaguang, Sedgwick, Adam C, Chen, Jingqin, Thiabaud, Gregory, Chau, Calvin, V, An, Jusung, Arambula, Jonathan F, He, XiaoPeng, Kim, Jong Seung, Sessler, Jonathan L, Liu, Chengbo. Manganese(II) Texaphyrin: A Paramagnetic Photoacoustic Contrast Agent Activated by Near-IR Light. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2020, 142(38): 16156-16160, https://www.webofscience.com/wos/woscc/full-record/WOS:000575684100004.
[6] Xie, Zhihua, Yang, Yanqing, He, Yaqiong, Shu, Chengyou, Chen, Dong, Zhang, Jinke, Chen, Jingqin, Liu, Chengbo, Sheng, Zonghai, Liu, Huadong, Liu, Jie, Gong, Xiaojing, Song, Liang, Dong, Shaohong. In vivo assessment of inflammation in carotid atherosclerosis by noninvasive photoacoustic imaging. THERANOSTICS[J]. 2020, 10(10): 4694-4704, https://www.webofscience.com/wos/woscc/full-record/WOS:000522665800029.
[7] Hu, Yiping, Zhang, Tiantian, Chen, Jingqin, Cheng, WenXiang, Chen, Jianhai, Zheng, Zhengtan, Lin, Jietao, Zhu, Guoyuan, Zhang, Yong, Bai, Xueling, Wang, Yan, Song, Bing, Wang, Qingwen, Qin, Ling, Zhang, Peng. Downregulation of Hypoxia-Inducible Factor-1 alpha by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats. MOLECULAR THERAPY-NUCLEIC ACIDS[J]. 2020, 19: 1330-1342, https://www.webofscience.com/wos/woscc/full-record/WOS:000519557700109.
[8] Chen, Qingshan, Chen, Jingqin, He, Mu, Bai, Yuanyuan, Yan, Huixiang, Zeng, Ning, Liu, Fangyan, Wen, Sai, Song, Liang, Sheng, Zonghai, Liu, Chengbo, Fang, Chihua. Novel small molecular dye-loaded lipid nanoparticles with efficient near-infrared-II absorption for photoacoustic imaging and photothermal therapy of hepatocellular carcinoma. BIOMATERIALS SCIENCE[J]. 2019, 7(8): 3165-3177, https://www.webofscience.com/wos/woscc/full-record/WOS:000476955100006.
[9] Sun, Shan, Chen, Jingqin, Jiang, Kai, Tang, Zhongdi, Wang, Yuhui, Li, Zhongjun, Liu, Chengbo, Wu, Aiguo, Lin, Hengwei. Ce6-Modified Carbon Dots for Multimodal-Imaging-Guided and Single-NIR-Laser-Triggered Photothermal/Photodynamic Synergistic Cancer Therapy by Reduced Irradiation Power. ACS APPLIED MATERIALS & INTERFACES[J]. 2019, 11(6): 5791-5803, http://dx.doi.org/10.1021/acsami.8b19042.
[10] Chen, Jingqin, Liu, Chengbo, Song, Liang, Zhang, YT, Carvalho, P, Magjarevic, R. Indocyanine Green Loaded, PEGylated, Reduced Graphene Oxide as a Highly Efficient Passive Targeting Contrast Agent for Photoacoustic/Fluorescence Dual-Modality Tumor Imaging. INTERNATIONAL CONFERENCE ON BIOMEDICAL AND HEALTH INFORMATICSnull. 2019, 64: 133-135, [11] Guo, Bing, Chen, Jingqin, Chen, Ningbo, Middha, Eshu, Xu, Shidang, Pan, Yutong, Wu, Min, Li, Ke, Liu, Chengbo, Liu, Bin. High-Resolution 3D NIR-II Photoacoustic Imaging of Cerebral and Tumor Vasculatures Using Conjugated Polymer Nanoparticles as Contrast Agent. ADVANCED MATERIALS[J]. 2019, 31(25): [12] Yang, Yanqing, Chen, Jingqin, Yang, Yuming, Xie, Zhihua, Song, Liang, Zhang, Peng, Liu, Chengbo, Liu, Jie. A 1064 nm excitable semiconducting polymer nanoparticle for photoacoustic imaging of gliomas. NANOSCALE[J]. 2019, 11(16): 7754-7760, [13] Yan, Huixiang, Chen, Jingqin, Li, Ying, Bai, Yuanyuan, Wu, Yunzhu, Sheng, Zonghai, Song, Liang, Liu, Chengbo, Zhang, Hai. Ultrasmall hybrid protein-copper sulfide nanoparticles for targeted photoacoustic imaging of orthotopic hepatocellular carcinoma with a high signal-to-noise ratio. BIOMATERIALS SCIENCE[J]. 2019, 7(1): 92-103, [14] Xu, Guiying, Bao, Xin, Chen, Jingqin, Zhang, Bohan, Li, Di, Zhou, Ding, Wang, Xiaoyun, Liu, Chengbo, Wang, Yingli, Qu, Songnan. In Vivo Tumor Photoacoustic Imaging and Photothermal Therapy Based on Supra-(Carbon Nanodots). ADVANCED HEALTHCARE MATERIALS[J]. 2019, 8(2): [15] Huang, Yi, Li, XiaoXia, Zhang, Lu, Chen, XiaoYan, Liu, ChengBo, Chen, JingQin, Wang, Yong, Shuai, XinTao. Multifunctional Nanoplatform Based on pH-responsive Micelle Coated with Discontinuous Gold Shell for Cancer Photothermo-chemotherapy and Photoacoustic Tomography. CHINESE JOURNAL OF POLYMER SCIENCE[J]. 2018, 36(10): 1139-1149, http://lib.cqvip.com/Qikan/Article/Detail?id=676209788.
[16] Chengbo Liu, Jingqin Chen, Ying Zhu, Xiaojing Gong, Rongqin Zheng, Ningbo Chen, Dong Chen, Huixiang Yan, Peng Zhang, Hairong Zheng, Zonghai Sheng, Liang Song. Highly Sensitive MoS2–Indocyanine Green Hybrid for Photoacoustic Imaging of Orthotopic Brain Glioma at Deep Site. 纳微快报:英文版. 2018, 115-126, http://lib.cqvip.com/Qikan/Article/Detail?id=78657879504849564851484949.
[17] Chen, Jingqin, Li, Xueshen, Liu, Xiaoyang, Yan, Huixiang, Xie, Zhihua, Sheng, Zonghai, Gong, Xiaojing, Wang, Lidai, Liu, Xin, Zhang, Peng, Zheng, Hairong, Song, Liang, Liu, Chengbo. Hybrid MoSe2-indocyanine green nanosheets as a highly efficient phototheranostic agent for photoacoustic imaging guided photothermal cancer therapy. BIOMATERIALS SCIENCE[J]. 2018, 6(6): 1503-1516, https://www.webofscience.com/wos/woscc/full-record/WOS:000433604100019.
[18] Bao, Xin, Yuan, Ye, Chen, Jingqin, Zhang, Bohan, Li, Di, Zhou, Ding, Jing, Pengtao, Xu, Guiying, Wang, Yingli, Hola, Katerina, Shen, Dezhen, Wu, Changfeng, Song, Liang, Liu, Chengbo, Zboril, Radek, Qu, Songnan. In vivo theranostics with near-infrared-emitting carbon dots-highly efficient photothermal therapy based on passive targeting after intravenous administration. LIGHT-SCIENCE & APPLICATIONS[J]. 2018, 7(1): http://ir.siat.ac.cn:8080/handle/172644/14228.
[19] 刘成波, 林日强, 冷吉, 陈敬钦, 龚小竞, 宋亮. 面向临床应用的光声成像技术. 中国医疗设备. 2018, 33(1): 1-5, http://lib.cqvip.com/Qikan/Article/Detail?id=7000407288.
[20] Liu, Chengbo, Chen, Jingqin, Zhu, Ying, Gong, Xiaojing, Zheng, Rongqin, Chen, Ningbo, Chen, Dong, Yan, Huixiang, Zhang, Peng, Zheng, Hairong, Sheng, Zonghai, Song, Liang. Highly Sensitive MoS2-Indocyanine Green Hybrid for Photoacoustic Imaging of Orthotopic Brain Glioma at Deep Site. NANO-MICRO LETTERS[J]. 2018, 10(3): http://ir.siat.ac.cn:8080/handle/172644/14212.
[21] Xu, Wenxiang, Chen, Jingqin, Sun, Shan, Tang, Zhongdi, Jiang, Kai, Song, Liang, Wang, Yuhui, Liu, Chengbo, Lin, Hengwei. Fluorescent and photoacoustic bifunctional probe for the detection of ascorbic acid in biological fluids, living cells and in vivo. NANOSCALE[J]. 2018, 10(37): 17834-17841, http://ir.nimte.ac.cn/handle/174433/17132.
[22] Wu, Meiying, Chen, Wenting, Chen, Yu, Zhang, Haixian, Liu, Chengbo, Deng, Zhiting, Sheng, Zonghai, Chen, Jingqin, Liu, Xin, Yan, Fei, Zheng, Hairong. Focused Ultrasound-Augmented Delivery of Biodegradable Multifunctional Nanoplatforms for Imaging-Guided Brain Tumor Treatment. ADVANCED SCIENCE[J]. 2018, 5(4): http://www.irgrid.ac.cn/handle/1471x/1790525.
[23] Jingqin Chen, Chengbo Liu, Liang Song, Zonghai Sheng, Hairong Zheng. Highly sensitive photoacoustic imaging of orthotopic brain tumor based on the amplified photoacoustic effect of single-layer MoS2 nanosheets. Nanomedicine: Nanotechnology, Biology, and Medicine. 2018, 14(5): 1799-1799, http://dx.doi.org/10.1016/j.nano.2017.11.165.
[24] Chen, Jingqin, Liu, Chengbo, Zeng, Guang, You, Yujia, Wang, Huina, Gong, Xiaojing, Zheng, Rongqin, Kim, Jeesu, Kim, Chulhong, Song, Liang. Indocyanine Green Loaded Reduced Graphene Oxide for In Vivo Photoacoustic/Fluorescence Dual-Modality Tumor Imaging. NANOSCALE RESEARCH LETTERS[J]. 2016, 11: [25] Chen, Jingqin, Liu, Chengbo, Hu, Dehong, Wang, Feng, Wu, Haiwei, Gong, Xiaojing, Liu, Xin, Song, Liang, Sheng, Zonghai, Zheng, Hairong. Single-Layer MoS2 Nanosheets with Amplified Photoacoustic Effect for Highly Sensitive Photoacoustic Imaging of Orthotopic Brain Tumors. ADVANCED FUNCTIONAL MATERIALS[J]. 2016, 26(47): 8715-8725, http://www.chinair.org.cn/handle/1471x/1747558.
[26] Jingqin Chen, Chengbo Liu, Guang Zeng, Yujia You, Huina Wang, Xiaojing Gong, Rongqin Zheng, Jeesu Kim, Chulhong Kim, Liang Song. Indocyanine Green Loaded Reduced Graphene Oxide for In Vivo Photoacoustic. Nanoscale Research Letters. 2016, 11(1): http://dx.doi.org/10.1186/s11671-016-1288-x.
[27] Liu, Chengbo, Gong, Xiaojing, Lin, Riqiang, Liu, Feng, Chen, Jingqin, Wang, Zhiyong, Song, Liang, Chu, Jun. Advances in Imaging Techniques and Genetically Encoded Probes for Photoacoustic Imaging. THERANOSTICSnull. 2016, 6(13): 2414-2430, https://www.webofscience.com/wos/woscc/full-record/WOS:000396551600011.
[28] Chen, Jingqin, Liu, Chengbo, Zeng, Guang, You, Yujia, Wang, Huina, Yan, Meng, Zheng, Rongqin, Song, Liang. Indocyanine green loaded, PEGylated, reduced graphene oxide as a highly efficient passive targeting contrast agent for photoacoustic/fluorescence dual-modality tumor imaging. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINEnull. 2016, 12(2): 515-515, http://dx.doi.org/10.1016/j.nano.2015.12.196.
[29] Chen, Jingqin, Liu, Hongyu, Zhao, Chubiao, Qin, Guiqi, Xi, Gaina, Li, Tan, Wang, Xiaoping, Chen, Tongsheng. One-step reduction and PEGylation of graphene oxide for photothermally controlled drug delivery. BIOMATERIALS[J]. 2014, 35(18): 4986-4995, http://dx.doi.org/10.1016/j.biomaterials.2014.02.032.
[30] Wang, Huina, Liu, Chengbo, Gong, Xiaojing, Hu, Dehong, Lin, Riqiang, Sheng, Zonghai, Zheng, Cuifang, Yan, Meng, Chen, Jingqin, Cai, Lintao, Song, Liang. In vivo photoacoustic molecular imaging of breast carcinoma with folate receptor-targeted indocyanine green nanoprobes. NANOSCALE[J]. 2014, 6(23): 14270-14279, https://www.webofscience.com/wos/woscc/full-record/WOS:000344997600026.

科研活动

   
科研项目
( 1 ) 针对类风湿性关节炎早期病理机制的近红外二区聚合物光声分子成像探针研究, 主持, 国家级, 2019-01--2021-12
( 2 ) 具有肿瘤微环境双响应功能的NIR-II卟啉光声探针及其应用研究, 主持, 国家级, 2022-01--2025-12