Jingqin Chen, an associate professor at SIAT CAS, was born in Huangshi, Hubei, China on Nov. 3, 1987. He obtained a Ph.D in Biochemistry and Molecular Biology from University of Chinese Academy of Sciences in 2020. His research interest focus on the synthesis of NIR photoacoustic moleculer imaging probes and their applications on biomedicine. The main probes include small molecule dye nanocomposite, 2D inorganic materials, organic polymer materials and porphyrin-based materials. Up to now, he has authored or co-authored 30 research publications, of which over 7 are in Journal with more than IF10, such as Advanced Materials, JACS, Advanced Functional Materials, Biomaterials, Light: Science & Applications, Nano-Micro Letters, Biomaterial Science, etc, and been an inventor of record on 9 issued China Patents.
Research Areas
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https://scholar.google.com/citations?user=JSD99uoAAAAJ&hl=zh-CN&oi=ao
Education
Publications
Papers
2021 (3)
1. Jingqin Chen#, Adam C. Sedgwick#, Sajal Sen#, Yaguang Ren, Qinchao Sun, Calvin Chau, Jonathan F. Arambula, Tridib Sarma*, Liang Song, Jonathan L. Sessler*, and Chengbo Liu*. Expanded porphyrins: Functional photoacoustic imaging agents that operate in the NIR-II region. Chemical Science, 2021, doi: 10.1039/D1SC01591E
2. Jianhai Chen, Wenxiang Cheng, Jian Li, Yan Wang, Jingqin Chen, Xin Shen, Ailing Su, Donghao Gan, Liqing Ke, Gang Liu, Jietao Lin, Liang Li, Xueling Bai, Peng Zhang*. Notch‐1 and Notch‐3 Mediates Hypoxia‐Induced Synovial Fibroblasts Activation in Rheumatoid Arthritis. Arthritis & Rheumatology. 2021, doi: 10.1002/art.41748
3. Junqing Hu, Mingzhou Wu, Shuqing He, Xin Hu, Jingqin Chen, Enna Ha, Fujin Ai, Tao Ji, Shuangchen Ruan*. A Near-Infrared Light Triggered Composite Nanoplatform for Synergetic Therapy and Multimodal Tumor Imaging. Frontiers in Chemistry, 2021, 9:695511.
2020 (5)
1. Yaguang Ren#, Adam C. Sedgwick#, Jingqin Chen#, Gregory Thiabaud, Calvin V. Chau, Jusung An, Jonathan F. Arambula, Xiao-Peng He, Jong Seung Kim*, Jonathan L. Sessler*, and Chengbo Liu*. Manganese (II) Texaphyrin: A Paramagnetic Photoacoustic Contrast Agent Activated by Near-IR Light. Journal of the American Chemical Society, 2020, 142(38): 16156-16160.
2. Jingqin Chen#, Ji Qi#, Chao Chen#, Jianhai Chen, Liangjian Liu, Rongkang Gao, Tiantian Zhang, Liang Song, Dan Ding*, Peng Zhang*, and Chengbo Liu*. Tocilizumab-Conjugated Polymer Nanoparticles for NIR-II Photoacoustic Imaging-Guided Therapy of Rheumatoid Arthritis. Advanced Materials, 2020, 32(37):2003399.
3. Xie Z, Yang Y, He Y, et al. In vivo assessment of inflammation in carotid atherosclerosis by noninvasive photoacoustic imaging. Theranostics, 2020, 10(10): 4694.
4. Hu Y, Zhang T, Chen J, et al. Downregulation of Hypoxia-Inducible Factor-1α by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats. Molecular Therapy-Nucleic Acids, 2020, 19: 1330-1342.
5. Yaxin Hu, Shan Xue, Ting Long, Peizhao Lyu, Xinyu Zhang, Jingqin Chen, Siping Chen, Chengbo Liu, Xin Chen. Opto-acoustic synergistic irradiation for vaporization of natural melanin-cored nanodroplets at safe energy levels and efficient sono-chemo-photothermal cancer therapy. Theranostics, 2020, 10(23): 10448.
2019 (6)
1. Qingshan Chen#, Jingqin Chen#, Mu He, Yuanyuan Bai, Huixiang Yan, Ning Zeng, Fangyan Liu, Sai Wen, Liang Song, Zonghai Sheng,* Chengbo Liu*, Chihua Fang*. Novel small molecular dye-loaded lipid nanoparticles with efficient near-infrared-II absorption for photoacoustic imaging and photothermal therapy of hepatocellular carcinoma. Biomaterials Science, 2019,7(8), 3165-3177.
2. Bing Guo #, Jingqin Chen#, Ningbo Chen#, Eshu Middha, Shidang Xu, Yutong Pan, Ke Li, Chengbo Liu*, Bin Liu*. High-Resolution 3D NIR-II Photoacoustic Imaging of Cerebral and Tumor Vasculatures Using Conjugated Polymer Nanoparticles as Contrast Agent. Advanced Materials, 2019, 31(25): 1808355.
3. Yanqing Yang#, Jingqin Chen#, Yuming Yang, Zhihua Xie, Liang Song, Peng Zhang*, Chengbo Liu*, and Jie Liu*. A 1064 nm excitable semiconducting polymer nanoparticle for photoacoustic imaging of gliomas. Nanoscale, 2019, 11(16), 7754-7760.
4. Shan Sun#, Jingqin Chen#, Kai Jiang, Zhongdi Tang, Yuhui Wang, Zhongjun Li, Chengbo Liu*, Aiguo Wu, and Hengwei Lin*. Ce6-modified carbon dots for multimodal-imaging-guided and single-NIR-laser-Triggered photothermal/photodynamic synergistic cancer therapy by reduced irradiation power." ACS applied materials & interfaces, 2019, 11 (6), 5791–5803.
5. Huixiang Yan#, Jingqin Chen#, Ying Li, Yuanyuan Bai, Yunzhu Wu, Zonghai Sheng, Liang Song, Chengbo Liu* and Hai Zhang*. Ultrasmall hybrid protein–copper sulfide nanoparticles for targeted photoacoustic imaging of orthotopic hepatocellular carcinoma with a high signal-to-noise ratio. Biomaterials Science, 2019, 7(1), 92-103.
6. Guiying Xu, Xin Bao, Jingqin Chen, Bohan Zhang, Di Li, Ding Zhou, Xiaoyun Wang, Chengbo Liu, Yingli Wang, Songnan Qu. In Vivo Tumor Photoacoustic Imaging and Photothermal Therapy Based on Supra‐(Carbon Nanodots). Advanced Healthcare Materials 8.2 (2019): 1800995.
2018 (7)
1. Xin Bao#, Ye Yuan#, Jingqin Chen#, Bohan Zhang, Di Li, Ding Zhou, Pengtao Jing, Guiying Xu, Yingli Wang, Kateřina Holá, Dezhen Shen, Changfeng Wu, Liang Song, Chengbo Liu*, Radek Zbořil* and Songnan Qu*. In vivo theranostics with near-infrared-emitting carbon dots—highly efficient photothermal therapy based on passive targeting after intravenous administration. Light: Science & Applications, 2018, 7(1), 91.
2. Wenxiang Xu#, Jingqin Chen#, Shan Sun#, Zhongdi Tang, Kai Jiang, Liang Song, Yuhui Wang*, Chengbo Liu* and Hengwei Lin*. Fluorescent and photoacoustic bifunctional probe for the detection of ascorbic acid in biological fluids, living cells and in vivo. Nanoscale, 2018, 10(37), 17834-17841.
3. Jingqin Chen, Xueshen Li, Xiaoyang Liu, Huixiang Yan, Zhihua Xie, Zonghai Sheng, Xiaojing Gong, Lidai Wang, Xin Liu, Peng Zhang, Hairong Zheng, Liang Song and Chengbo Liu*. Hybrid MoSe2–indocyanine green nanosheets as a highly efficient phototheranostic agent for photoacoustic imaging guided photothermal cancer therapy. Biomaterials Science, 2018, 6 (6):1503-1516.
4. Chengbo Liu#, Jingqin Chen#, Ying Zhu#, Xiaojing Gong, Rongqin Zheng, Ningbo Chen, Dong Chen, Huixiang Yan, Peng Zhang, Hairong Zheng, Zonghai Sheng*, Liang Song*. Highly sensitive MoS2–indocyanine green hybrid for photoacoustic imaging of orthotopic brain glioma at deep site. Nano-Micro Letters, 2018, 10: 1-12.
5. Meiying Wu, Wenting Chen, Yu Chen, Haixian Zhang, Chengbo Liu, Zhiting Deng, Zonghai Sheng, Jingqin Chen, Xin Liu, Fei Yan*, Hairong Zheng*. Focused Ultrasound-Augmented Delivery of Biodegradable Multifunctional Nanoplatforms for Imaging-Guided Brain Tumor Treatment. Advanced Science, 2018, 5(4):1700474.
6. Yi Huang, Xiaoxia Li, Lu Zhang, Xiaoyan Chen, Chengbo Liu, Jingqin Chen, Yong Wang, Xintao Shuai. Multifunctional nanoplatform based on pH-responsive micelle coated with discontinuous gold shell for cancer photothermo-chemotherapy and photoacoustic tomography. Chinese Journal of Polymer Science, 2018, 36(10): 1139-1149.
7. 林日强，冷吉，陈敬钦，刘成波，龚小竞，宋亮. 面向临床应用的光声成像技术. 中国医疗设备, 2018, 33(1): 1-5.
2016 (3)
1. Jingqin Chen#, Chengbo Liu#, Dehong Hu, Feng Wang, Haiwei Wu, Xiaojing Gong, Xin Liu, Liang Song*, Zonghai Sheng*, Hairong Zheng*. Single‐layer MoS2 nanosheets with amplified photoacoustic effect for highly sensitive photoacoustic imaging of orthotopic brain tumors. Advanced Functional Materials, 2016, 26(47): 8715-8725.
2. Jingqin Chen#, Chengbo Liu#, Guang Zeng, Yujia You, Huina Wang, Xiaojing Gong, Rongqin Zheng, Jeesu Kim, Chulhong Kim and Liang Song*. Indocyanine green loaded reduced graphene oxide for in vivo photoacoustic/fluorescence dual-modality tumor imaging. Nanoscale Research Letters, 2016, 11(1): 1-11.
3. Chengbo Liu, Xiaojing Gong, Riqiang Lin, Feng Liu, Jingqin Chen, Zhiyong Wang, Liang Song*, Jun Chu*. Advances in Imaging Techniques and Genetically Encoded Probes for Photoacoustic Imaging, Theranostics, 2016, 6(13): 2414-2430.
2014 (4)
1. Jingqin Chen, Hongyu Liu, Chubiao Zhao, Guiqi Qin, Gaina Xi, Tan Li, Xiaoping Wang, Tongsheng Chen*. One-step reduction and PEGylation of graphene oxide for photothermally controlled drug delivery. Biomaterials, 2014, 35(18): 4986-4995.
2. Jingqin Chen, Xiaoping Wang and Tongsheng Chen*. Facile and green reduction of covalently PEGylated nanographene oxide via a ‘water-only’route for high-efficiency photothermal therapy. Nanoscale Research Letter, 2014, 9(1): 86.
3. Huina Wang#, Chengbo Liu#, Xiaojing Gong, Dehong Hu, Riqiang Lin, Zonghai Sheng, Cuifang Zheng, Meng Yan, Jingqin Chen, Lintao Cai and Liang Song*. In vivo photoacoustic molecular imaging of breast carcinoma with folate receptor-targeted indocyanine green nanoprobes, Nanoscale, 2014, 6, 14270-14279.
4. Chubiao Zhao, Guiqi Qin, Weijie Gao, Jingqin Chen, Hongyu Liu, Gaina Xi, Tan Li, Shengnan Wu, Tongsheng Chen*. Potent proapoptotic actions of dihydroartemisinin in gemcitabine-resistant A549 cells. Cellular Signalling, 2014, 26(10): 2223-2233.