基本信息
高兆明  男  博导  中国科学院深海科学与工程研究所
电子邮件: gaozm@idsse.ac.cn
通信地址: 海南省三亚市鹿回头路28号
邮政编码: 572000

研究领域

1. 深海极端环境条件下的微生物群落生态及压力等关键环境因子适应机制,深海特有微生命类群。

2. 近岸及深海环境中海绵共生微生物群落特征,典型共生微生物的基因组学特征和共生适应性机制。

招生信息

   
招生专业
070703-海洋生物学
招生方向
深海微生物学
生物信息学
共生微生物

教育背景

2006-09--2011-06   山东大学   理学博士
2002-09--2006-06   山东大学   理学学士

工作经历

   
工作简历
2015-12~现在, 中国科学院深海科学与工程研究所, 副研究员
2014-03~2015-11,中国科学院深海科学与工程研究所, 助理研究员
2012-05~2014-06,香港科技大学, 访问学者/博士后
2011-11~2014-11,国家海洋局第三海洋研究所, 博士后

专利与奖励

   
专利成果
[1] 韩壮, 王佳伟, 翟吉安, 高兆明. 深海链霉菌、Tianyamycin系列化合物及其应用. CN: CN113308407B, 2023-08-18.

[2] 韩壮, 王佳伟, 翟吉安, 高兆明. 深海链霉菌、Tianyamycin系列化合物及其应用. CN: CN113308407A, 2021-08-27.

[3] 李文莉, 王勇, 位站飞, 李俊, 高兆明, 贺丽生. 用于深海微生物原位细胞裂解的组合物、试剂、试剂盒及应用. CN: CN111534509A, 2020-08-14.

[4] 李俊, 辛永智, 蔡笃思, 李文莉, 王勇, 王绥学, 王瑞星, 陈俊, 高兆明, 贺丽生. 一种全海深微生物核酸原位提取装置. CN: CN109852532A, 2019-06-07.

[5] 李俊, 辛永智, 蔡笃思, 李文莉, 王勇, 王绥学, 王瑞星, 陈俊, 高兆明, 贺丽生. 一种全海深微生物核酸原位提取装置. CN: CN209854124U, 2019-12-27.

[6] 李俊, 王勇, 蔡笃思, 高兆明, 贺丽生, 张艾群, 高怀宁. 一种应用于全海深的微生物原位自动化富集固定装置. CN: CN205241694U, 2016-05-18.

[7] 李俊, 王勇, 蔡笃思, 高兆明, 贺丽生, 张艾群, 高怀宁. 一种应用于全海深的微生物原位自动化富集固定装置及方法. CN: CN105420097A, 2016-03-23.

出版信息

   
发表论文
[1] Yitao Lin, Jack Chi-Ho Ip, Xing He, 高兆明, Maëva Perez, Ting Xu, Jin Sun, Pei-Yuan Qian, Jian-Wen Qiu. Scallop-bacteria symbiosis from the deep sea reveals strong genomic coupling in the absence of cellular integration. The ISME Journal[J]. 2024, [2] Peikuan Xu, Ming Yang, Lisheng He, Zhang Hongxi, 高兆明, Yuelu Jiang, Yong Wang. Discovery of Prevalent Ciliophora, Discoba, and Copepoda Protists in Deep Sea Water by In Situ Nucleotide Extraction. Journal of Marine Science and Engineering[J]. 2024, [3] Wang, Yan, Gong, Lin, Gao, Zhaoming, Wang, Yong, Zhao, Feng, Fu, Lulu, Li, Xinzheng. Host-specific bacterial communities associated with six cold-seep sponge species in the South China Sea. FRONTIERS IN MARINE SCIENCE[J]. 2023, 10: 14-, https://doaj.org/article/e57bcaef931f4f4ba63ae4175c457b3b.
[4] Zhao-Ming Gao, Ting Xu, Hua-Guan Chen, Rui Lu, Jun Tao, Hong-Bin Wang, Jian-Wen Qiu, Yong Wang. Early genome erosion and internal phage-symbiont-host interaction in the endosymbionts of a cold-seep tubeworm. iScience[J]. 2023, 接收-, [5] Wei, TaoShu, Gao, ZhaoMing, Gong, Lin, Li, QingMei, Zhou, YingLi, Chen, HuaGuan, He, LiSheng, Wang, Yong. Genome-centric view of the microbiome in a new deep-sea glass sponge species Bathydorus sp.. FRONTIERS IN MICROBIOLOGY[J]. 2023, 14: http://dx.doi.org/10.3389/fmicb.2023.1078171.
[6] Wang, Yong, Li, Wenli, Baker, Brett J, Zhou, Yingli, He, Lisheng, Danchin, Antoine, Li, Qingmei, Gao, Zhaoming. Carbon metabolism and adaptation of hyperalkaliphilic microbes in serpentinizing spring of Manleluag, the Philippines. ENVIRONMENTAL MICROBIOLOGY REPORTS[J]. 2022, 14(2): 308-319, http://dx.doi.org/10.1111/1758-2229.13052.
[7] Cui, Guojie, Zhou, Yingli, Li, Wenli, Gao, Zhaoming, Huang, Jiaomei, Wang, Yong. A novel bacterial phylum that participates in carbon and osmolyte cycling in the Challenger Deep sediments. ENVIRONMENTAL MICROBIOLOGY[J]. 2021, 23(7): 3758-3772, [8] Wang, Yong, Li, Wenli, Li, Qingmei, Zhou, Yingli, Gao, Zhaoming, Feng, Dong. Deep-Sea Carbonates Are a Reservoir of Fossil Microbes Previously Inhabiting Cold Seeps. FRONTIERS IN MARINE SCIENCE[J]. 2021, 8: http://dx.doi.org/10.3389/fmars.2021.698945.
[9] Lu, Rui, Gao, ZhaoMing, Li, WenLi, Wei, ZhanFei, Wei, TaoShu, Huang, JiaoMei, Li, Meng, Tao, Jun, Wang, HongBin, Wang, Yong. Asgard archaea in the haima cold seep: Spatial distribution and genomic insights. DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS[J]. 2021, 170: http://dx.doi.org/10.1016/j.dsr.2021.103489.
[10] Cuil, Guojie, Li, Jun, Gao, Zhaoming, Wang, Yong. Spatial variations of microbial communities in abyssal and hadal sediments across the Challenger Deep. PEERJ[J]. 2019, 7(2019): http://ir.idsse.ac.cn/handle/183446/6803.
[11] Gao, ZhaoMing, Huang, JiaoMei, Cui, GuoJie, Li, WenLi, Li, Jun, Wei, ZhanFei, Chen, Jun, Xin, YongZhi, Cai, DuSi, Zhang, AiQun, Wang, Yong. In situ meta-omic insights into the community compositions and ecological roles of hadal microbes in the Mariana Trench. ENVIRONMENTAL MICROBIOLOGY[J]. 2019, 21(11): 4092-4108, http://dx.doi.org/10.1111/1462-2920.14759.
[12] Wang, Yong, Huang, JiaoMei, Cui, GuoJie, Nunoura, Takuro, Takaki, Yoshihiro, Li, WenLi, Li, Jun, Gao, ZhaoMing, Takai, Ken, Zhang, AiQun, Stepanauskas, Ramunas. Genomics insights into ecotype formation of ammonia-oxidizing archaea in the deep ocean. ENVIRONMENTAL MICROBIOLOGY[J]. 2019, 21(2): 716-729, http://ir.idsse.ac.cn/handle/183446/6677.
[13] Li, Wen Li, Huang, JiaoMei, Zhang, PeiWei, Cui, GuoJie, Wei, ZhanFei, Wu, YuZhi, Gao, ZhaoMing, Han, Zhuang, Wang, Yong. Periodic and Spatial Spreading of Alkanes and Alcanivorax Bacteria in Deep Waters of the Mariana Trench. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2019, 85(3): http://dx.doi.org/10.1128/AEM.02089-18.
[14] Wang, Yong, Gao, ZhaoMing, Li, Jun, He, LiSheng, Cui, GuoJie, Li, WenLi, Chen, Jun, Xin, YongZhi, Cai, DuSi, Zhang, AiQun. Hadal water sampling by in situ microbial filtration and fixation (ISMIFF) apparatus. DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS[J]. 2019, 144(1): 132-137, http://ir.idsse.ac.cn/handle/183446/6665.
[15] Wang, Kun, Shen, Yanjun, Yang, Yongzhi, Gan, Xiaoni, Liu, Guichun, Hu, Kuang, Li, Yongxin, Gao, Zhaoming, Zhu, Li, Yan, Guoyong, He, Lisheng, Shan, Xiujuan, Yang, Liandong, Lu, Suxiang, Zeng, Honghui, Pan, Xiangyu, Liu, Chang, Yuan, Yuan, Feng, Chenguang, Xu, Wenjie, Zhu, Chenglong, Xiao, Wuhan, Done, Yang, Wang, Wen, Qiu, Qiang, He, Shunping. Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation. NATURE ECOLOGY & EVOLUTION[J]. 2019, 3(5): 823-833, http://ir.idsse.ac.cn/handle/183446/6795.
[16] Ding, Wei, Zhang, Weipeng, Wang, Ruojun, Sun, Yanan, Pei, Bite, Gao, Zhaoming, Qian, PeiYuan. Distribution, diversity and functional dissociation of the mac genes in marine biofilms. BIOFOULING[J]. 2019, 35(2): 230-243, http://ir.idsse.ac.cn/handle/183446/6744.
[17] Gao, ZhaoMing, Zhou, GuoWei, Huang, Hui, Wang, Yong. The Cyanobacteria-Dominated Sponge Dactylospongia elegans in the South China Sea: Prokaryotic Community and Metagenomic Insights. FRONTIERS IN MICROBIOLOGY[J]. 2017, 8: https://doaj.org/article/60dd977d31e246c6bd41bd556c2b9a44.
[18] Shen, Yanjun, Dai, Wei, Gao, Zhaoming, Yan, Guoyong, Gan, Xiaoni, He, Shunping. Molecular phylogeny and divergence time estimates using the mitochondrial genome for the hadal snailfish from the Mariana trench. SCIENCE BULLETIN[J]. 2017, 62(16): 1106-1108, http://ir.idsse.ac.cn/handle/183446/4758.
[19] Wang, Yong, Li, Tie Gang, Wang, Meng Ying, Lai, Qi Liang, Li, Jiang Tao, Gao, Zhao Ming, Shao, Zong Ze, Qian, PeiYuan. Archive of bacterial community in anhydrite crystals from a deep-sea basin provides evidence of past oil-spilling in a benthic environment in the Red Sea. BIOGEOSCIENCES[J]. 2016, 13(23): 6405-6417, https://doaj.org/article/44e9650233094e22a8015cf7f652a54e.
[20] Wang Yong, Gao Zhaoming, Xu Ying, Li Guangyu, He Lisheng, Qian Peiyuan. An evaluation of multiple annealing and looping based genome amplification using a synthetic bacterial community. ACTA OCEANOLOGICA SINICA[J]. 2016, 35(2): 131-136, http://lib.cqvip.com/Qikan/Article/Detail?id=667983978.
[21] Wang, Yong, Huang, JiaoMei, Wang, ShaoLu, Gao, ZhaoMing, Zhang, AiQun, Danchin, Antoine, He, LiSheng. Genomic characterization of symbiotic mycoplasmas from the stomach of deep-sea isopod bathynomus sp. ENVIRONMENTAL MICROBIOLOGY[J]. 2016, 18(8): 2646-2659, https://www.webofscience.com/wos/woscc/full-record/WOS:000383388800032.
[22] Wang, Yong, Gao, ZhaoMing, Li, JiangTao, Bougouffa, Salim, Tian, Ren Mao, Bajic, Vladimir B, Qian, PeiYuan. Draft genome of an Aerophobetes bacterium reveals a facultative lifestyle in deep-sea anaerobic sediments. SCIENCE BULLETIN[J]. 2016, 61(15): 1176-1186, http://ir.idsse.ac.cn/handle/183446/1603.
[23] Wang Yong. Wang Y, Huang JM, Wang SL, Gao ZM, Zhang AQ, Danchin A*, He LS*. 2016. Genomic characterization of symbiotic mycoplasmas from the stomach of deep-sea isopod bathynomus sp. 18(8): 13411. Environmental Microbiology,. 2016, [24] Gao, ZhaoMing, Wang, Yong, Tian, RenMao, Lee, On On, Wong, Yue Him, Batang, Zenon B, AlSuwailem, Abdulaziz, Lafi, Feras F, Bajic, Vladimir B, Qian, PeiYuan. Pyrosequencing revealed shifts of prokaryotic communities between healthy and disease-like tissues of the Red Sea sponge Crella cyathophora. PEERJ[J]. 2015, 3(NO): http://124.16.218.2:8080/handle/183446/500.
[25] Wang, Yong, Li, Jiang Tao, He, Li Sheng, Yang, Bo, Gao, Zhao Ming, Cao, Hui Luo, Batang, Zenon, AlSuwailem, Abdulaziz, Qian, PeiYuan. Zonation of Microbial Communities by a Hydrothermal Mound in the Atlantis II Deep (the Red Sea). PLOS ONE[J]. 2015, 10(10): http://ir.idsse.ac.cn/handle/183446/1214.
[26] Gao, ZhaoMing, Xu, Xun, Ruan, LingWei. Enrichment and characterization of an anaerobic cellulolytic microbial consortium SQD-1.1 from mangrove soil. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2014, 98(1): 465-474, http://dx.doi.org/10.1007/s00253-013-4857-2.
[27] Gao, ZhaoMing, Wang, Yong, Tian, RenMao, Wong, Yue Him, Batang, Zenon B, AlSuwailem, Abdulaz M, Bajic, Vladimir B, Qian, PeiYuan. Symbiotic Adaptation Drives Genome Streamlining of the Cyanobacterial Sponge Symbiont "Candidatus Synechococcus spongiarum". MBIO[J]. 2014, 5(2): http://124.16.218.2:8080/handle/183446/457.
[28] Gao, ZhaoMing, Wang, Yong, Lee, On On, Tian, RenMao, Wong, Yue Him, Bougouffa, Salim, Batang, Zenon, AlSuwailem, Abdulaziz, Lafi, Feras F, Bajic, Vladimir B, Qian, PeiYuan. Pyrosequencing Reveals the Microbial Communities in the Red Sea Sponge Carteriospongia foliascens and Their Impressive Shifts in Abnormal Tissues. MICROBIAL ECOLOGY[J]. 2014, 68(3): 621-632, http://124.16.218.2:8080/handle/183446/762.
[29] Tian, RenMao, Wang, Yong, Bougouffa, Salim, Gao, ZhaoMing, Cai, Lin, Bajic, Vladimir, Qian, PeiYuan. Genomic analysis reveals versatile heterotrophic capacity of a potentially symbiotic sulfur-oxidizing bacterium in sponge. ENVIRONMENTAL MICROBIOLOGY[J]. 2014, 16(11): 3548-3561, https://www.doi.org/10.1111/1462-2920.12586.
[30] Tian, RenMao, Wang, Yong, Bougouffa, Salim, Gao, ZhaoMing, Cai, Lin, Zhang, WeiPeng, Bajic, Vladimir, Qian, PeiYuan. Effect of Copper Treatment on the Composition and Function of the Bacterial Community in the Sponge Haliclona cymaeformis. MBIO[J]. 2014, 5(6): http://124.16.218.2:8080/handle/183446/771.

科研活动

   
科研项目
( 1 ) 基于高通量测序的冷泉区海绵Myxilla methanophila共生菌代谢方式和共生机制的研究, 负责人, 国家任务, 2015-01--2017-12
( 2 ) 南海北部九龙甲烷礁冷泉表层沉积物的微生物群落结构和宏基因组学研究, 参与, 国家任务, 2015-01--2018-12
( 3 ) 海斗深渊前沿科技问题研究与公关之“深渊微生物功能组学研究”, 参与, 中国科学院计划, 2014-01--2018-12
( 4 ) 深海微生物原位自动化富集固定取样器的设计与应用, 负责人, 研究所自主部署, 2014-10--2016-09
( 5 ) 西沙晋卿岛海域Ircinia属海绵共生微生物空间分布结构及组学水平上的功能分析, 负责人, 地方任务, 2017-01--2017-12
( 6 ) 中国科学院青年创新促进会项目, 负责人, 中国科学院计划, 2017-01--2020-12
( 7 ) 深海生物功能基因原位检测与传感系统研制, 参与, 国家任务, 2016-07--2020-06
( 8 ) 国家(省)重点科技项目三亚市配套资金, 负责人, 地方任务, 2016-01--2017-12
( 9 ) 南海冷泉化能合成生态系统的微生物组学与共生关系研究, 负责人, 国家任务, 2018-08--2021-12
( 10 ) 南海冷泉化能合成生态系统的微生物组学研究, 负责人, 地方任务, 2019-12--2022-12
( 11 ) 冷泉Sclerolinum新型管状蠕虫共生功能体的共生演化与生态角色分析, 负责人, 国家任务, 2021-01--2024-12
( 12 ) 典型海底流体系统优势微生物类群的环境适应和共生演化机制, 负责人, 国家任务, 2022-12--2026-12
( 13 ) 深海原位病毒组学研究, 负责人, 国家任务, 2022-12--2026-05

指导学生

已指导学生

魏韬书  硕士研究生  070703-海洋生物学  

陆瑞  硕士研究生  085238-生物工程  

现指导学生

陈华冠  硕士研究生  070703-海洋生物学  

李渝航  硕士研究生  070703-海洋生物学  

冉海力  硕士研究生  070703-海洋生物学