Dr. Penghui Li, Associate Professor

Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences

Research Areas

nano-assembled structures; SERS; optical biosensors and biodetection



Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences 

Associate Professor 



Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences 

Postdoctoral Researcher 


(1)    K. Zheng, J. X. Bai, W. L. Chen, Y. Z. Xu, H. L. Yang, W. Li, P. H. Li*, L. P. Tong*, H. Y. Wang*, P. K. Chu, D. C. Geng*. Multifunctional BPs/MT@PLGA-ALE nanospheres for treatment of osteoporotic fracture with near-infrared irradiation. Advanced Functional Materials, 33: 2214126 (2023). 
(2)    W. L. Chen, W. L. Wang, H. Y. Xing, W. Li, H. W. He, W. Li, P. K. Chu, G. F. Song, H. Y. Wang*, P. H. Li*. Interfacial self-assembled dual-functional nanocomposite films for SERS monitoring of visible-light photocatalytic degradation of organic dye pollutants. Surfaces and Interfaces, 38: 102808 (2023). 
(3)    G. F. Song, H. W. He, W. L. Chen, Y. L. Lv, P. K. Chu, H. Y. Wang*, P. H. Li*. Reversibly migratable fluorescent probe for precise and dynamic evaluation of cell mitochondrial membrane potentials. Biosensors, 12(10): 798 (2022).
(4)    W. Li, Y. Y. Sun*, W. L. Chen, G. F. Song, M.Y. Huang, J. Xu, X. X. Shi, P. H. Li*. Hollow RuCu bimetallic nanospheres as emerging SERS substrates for illegal food additives detection. Materials Letters, 327: 133053 (2022).
(5)    G. F. Song, L. Yan, Q. Liao, W. L. Chen, L. P. Tong, Y. Zeng, P. K. Chu, P. H. Li*, H. Y. Wang*. Mitochondria/RNA cascade-targeted and fluorescence-switchable photosensitizer for photodynamic therapy augmentation and real-time efficacy self-monitoring. Sensors and Actuators B. Chemical, 369, 132260 (2022).
(6)    J. Chen, J. Q. Yang, W. L. Chen*, Y. F. Wang, G. F. Song, H. W. He, H. Y. Wang, P. H. Li*, G. P. Wang*. Tri-functional SERS nanoplatform with tunable plasmonic property for synergistic antibacterial activity and antibacterial process monitoring. Journal of Colloid and Interface Science, 608: 2266-2277 (2022).
(7)    W. L. Chen, F. Long, G. F. Song, J. Chen, S. Peng, P. H. Li*. Rapid and sensitive detection of pesticide residues using dynamic surface-enhanced Raman spectroscopy. Journal of Raman Spectroscopy, 51(4): 611-618 (2020).
(8)     P. H. Li, F. Long, W. L. Chen, J. Chen, P. K. Chu*, H. Y. Wang*. Fundamentals and applications of surface-enhanced Raman spectroscopy-based biosensors. Current Opinion in Biomedical Engineering, 13: 51-59 (2020). 
(9)    F. Long, W. Li, W. L. Chen, D. N. Liu, Y. Chen*, R. Zhou*, P. H. Li*. An amperometric biosensor based on Cu2O@Au nanocomposites for the detection of galectin-1 via lactose-galectin interactions. Nanotechnology, 30: 485706 (2019).
(10) P. H. Li, W. L. Chen, D. N. Liu, H. Huang, K. Dan, X. N. Hu, S. Z. Yu, P. K. Chu*, X.-F. Yu*. Template growth of Au/Ag nanocomposites on phosphorene for sensitive SERS detection of pesticides. Nanotechnology, 30: 275604 (2019).
(11)  L. Zhang, Z. Yang, W. Zhu, Z. L. Ye, Y. M. Yu, Z. S. Xu*, J. H. Ren*, P. H. Li*.Dual-stimuli-responsive, polymer-microsphere-encapsulated CuS nanoparticles for magnetic resonance imaging guided synergistic chemo-photothermal therapy. ACS Biomaterials Science & Engineering, 3: 1690-1701 (2017).
(12) W. Zhu, S. Liang, J. Wang, Z, Yang, L. Zhang, T. M. Yuan, Z. S. Xu*, H. B. Xu*, P. H. Li*. Europium-phenolic network coated BaGdF5 nanocomposites for tri-modal computed tomography/magnetic resonance/luminescence imaging. Journal of Materials Science: Materials in Medicine, 28: 74 (2017).
(13) S. Y. Tang, Y. Li, H. Huang, P. H. Li*, Z. N. Guo, Q. Luo*, Z. Wang, P. K. Chu, J. Li, X.-F. Yu*. Efficient enrichment and self-assembly of hybrid nanoparticles into removable and magnetic SERS substrates for sensitive detection of environmental pollutants. ACS Applied Materials & Interfaces, 9(8): 7472-7480 (2017).
(14) P. H. Li, Y. Li, Z.-K. Zhou, S. Y. Tang, X.-F. Yu*, S. Xiao, Z. Z. Wu, Q. L. Xiao, Y. T. Zhao, H. Y. Wang, P. K. Chu*. Evaporative self-assembly of gold nanorods into macroscopic 3D plasmonic superlattice arrays. Advanced Materials, 28(13): 2511-2517 (2016). 
(15) P. H. Li, P. K. Chu*. Thin film deposition technologies and processing of biomaterials. Thin Film Coatings for Biomaterials and Biomedical Applications, Chapter 1, 3-28 (2016). 
(16)  P. H. Li, L. M. Li, W. H. Wang, W. H. Jin, X. M. Liu, K. W. K. Yeung, P. K. Chu*. Enhanced corrosion resistance and hemocompatibility of biomedical NiTi alloy by atmospheric-pressure plasma polymerized fluorine-rich coating. Applied Surface Science, 297: 109-115 (2014).
(17) P. H. Li, X. M. Zhang, R. Z. Xu, W. H. Wang. X. M. Liu, K. W. K. Yeung, P. K. Chu*. Electrochemically deposited chitosan/Ag complex coating on biomedical NiTi alloy for antibacterial application. Surface & Coatings Technology, 232: 370-375 (2013).
(18) P. H. Li, R. Z. Xu, W. H. Wang, X. L. Li, Z. S. Xu, K. W. K. Yeung, P. K. Chu*.Thermosensitive poly(N-isopropylacrylamide-co-glycidyl methacrylate) microgels for controlled drug release. Colloids and Surfaces B: Biointerfaces, 101: 251-255 (2013).
(19) P. H. Li, G. S. Wu, R. Z. Xu, W. H. Wang, S. L. Wu, K. W. K. Yeung, P. K. Chu*. In vitro corrosion inhibition on biomedical shape memory alloy by plasma-polymerized allylamine film. Materials Letters, 89: 51-54 (2012).
(20) P. H. Li, X. X. Hu, G. W. Song, P. K. Chu, Z. S. Xu*. Facile preparation of cationic P(St-BA-METAC) copolymer nanoparticles and the investigation of their interaction with bovine serum albumin. Journal of Applied Polymer Science, 125(2): 864-869 (2012).
(21) P. H. Li, X. X. Hu, S. L. Wu, P. K. Chu, K. W. K. Yeung, Z. S. Xu*. Cationic lanthanide luminescent copolymer: Design, synthesis and interaction with DNA. Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 48(10): 832-839 (2011).