Tao YU     

Supervisor of Doctorate Candidates

Supervisor of Master's Candidates


Department: Institute of Synthetic Biology,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences

Lab webpage:

Address:1068 Xueyuan Boulevard, University Town of Shenzhen, Xili Nanshan, Shenzhen,518055,China

Research Areas

Synthetic Biology and Metabolic Engineering


Ph.D.  Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

B.S.  Shandong University


Work Experience

Professor, Institute of Synthetic Biology, SIAT, CAS, 2019-date

Postdoctoral Research Associate, Chalmers, 2015-2019



[1]Yu T*, Dabirian Y*, Liu Q, Siewers V, Nielsen J. (2019) Strategies and Challenges for Metabolic Rewiring. Current Opinion in Systems Biology 15:30-38(*co-first author)

[2]Liu, Q.,Yu, T.,Li, X.,Chen, Y.,Campbell, K.,Nielsen, J.,Chen, Y. (2019) Rewiring carbon metabolism in yeast for high level production of aromatic chemicals. Nature Communications 10:4976

[3]Yu T*, Zhou Y .J.J*, Huang M, Liu Q, Pereira R, David F, Nielsen J. (2018) Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis. Cell 174(6):1549-1558 (*co-first author)

[4]Yu, T., Zhou, Y.J.J., Wenning, L., Liu, Q.L., Krivoruchko, A., Siewers, V., Nielsen, J., and David, F. (2017) Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals. Nature Communications 8:15587

[5]Wenning, L.,Yu, T.,David, F,Nielsen, J.,Siewers,V(2017)Establishing Very Long-Chain Fatty Alcohol and Wax Ester Biosynthesis in Saccharomyces cerevisiae. Biotechnology and Bioengineering 114:1025–1035

[6]Yu, T., Tao, Y., Yang, M., Chen, P., Gao, X., Zhang, Y., Zhang, T., Chen, Z., Hou, J., Zhang, Y.,Ruan,K., Wang,H., Hu,R.G.* (2014)  Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis. Cell Research 24:1214-1230