070208-无线电物理

小动物脑疾病的磁共振成像研究

2002-09--2008-06 中国科学院武汉物理与数学研究所 博士学位

   

2008-07--今 中国科学院武汉物理与数学研究所 工作

   

[1] Wang, Xuxia, Li, Ronghui, He, Rui, Fang, Fang. Effects of repeated manganese treatment on proton magnetic resonance spectra of the globus pallidus in rat brain. NMR IN BIOMEDICINE. 2021, http://dx.doi.org/10.1002/nbm.4617.
[2] 胡赢丹, 蔡悦, 王旭霞, 刘思婕, 康彦, 雷皓, 林富春. 尼古丁易感的脑结构特征的磁共振成像研究. 波谱学杂志. 2021, 38(3): 345-355, http://lib.cqvip.com/Qikan/Article/Detail?id=7105477469.
[3] Li, Ronghui, Wang, Xuxia, Lin, Fuchun, Song, Tao, Zhu, Xutao, Lei, Hao. Mapping accumulative whole-brain activities during environmental enrichment with manganese-enhanced magnetic resonance imaging. NEUROIMAGE[J]. 2020, 210: http://dx.doi.org/10.1016/j.neuroimage.2020.116588.
[4] Gao, Lifeng, Huang, Mingming, Luo, Xiaowen, Song, Tao, Wang, Xuxia, Wang, Zhe, Zhang, Wei, Chen, Jiangyuan, Lei, Hao. Microstructure abnormity in the optic nerve of type 1 diabetic rats revealed by diffusion tensor imaging study. MAGNETIC RESONANCE IMAGING[J]. 2020, 71: 105-114, http://dx.doi.org/10.1016/j.mri.2020.05.003.
[5] Zhou, Wenchang, Cai, Aoling, Nie, Binbin, Zhang, Wen, Yang, Ting, Zheng, Ning, Manyande, Anne, Wang, Xuxia, Xu, Fuqiang, Tian, Xuebi, Wang, Jie. Investigation of robust visual reaction and functional connectivity in the rat brain induced by rocuronium bromide with functional MRI. AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH[J]. 2020, 12(6): 2396-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000548245700005.
[6] Zhou, YiFan, Li, YaNan, Jin, HuiJuan, Wu, JieHong, He, QuanWei, Wang, XuXia, Lei, Hao, Hu, Bo. Sema4D/PlexinB1 inhibition ameliorates blood-brain barrier damage and improves outcome after stroke in rats. FASEB JOURNAL[J]. 2018, 32(4): 2181-2196, http://202.127.146.157/handle/2RYDP1HH/4937.
[7] Li, Shuang, Wang, Xinghua, Yang, Junjie, Lei, Hao, Wang, Xuxia, Xiang, Yi. Metabolic profile of visual cortex in diabetic rats measured with in vivo proton MRS. NMR IN BIOMEDICINE[J]. 2017, 30(11): http://dx.doi.org/10.1002/nbm.3783.
[8] Wu, H, Wang, X, Gao, Y, Lin, F, Song, T, Zou, Y, Xu, L, Lei, H. NMDA RECEPTOR ANTAGONISM BY REPETITIVE MK801 ADMINISTRATION INDUCES SCHIZOPHRENIA-LIKE STRUCTURAL CHANGES IN THE RAT BRAIN AS REVEALED BY VOXEL-BASED MORPHOMETRY AND DIFFUSION TENSOR IMAGING. NEUROSCIENCE[J]. 2016, 322: 221-233, http://dx.doi.org/10.1016/j.neuroscience.2016.02.043.
[9] Wang, Xuxia, Lin, Fuchun, Gao, Yunling, Lei, Hao. Bilateral common carotid artery occlusion induced brain lesions in rats: A longitudinal diffusion tensor imaging study. MAGNETIC RESONANCE IMAGING[J]. 2015, 33(5): 551-558, http://dx.doi.org/10.1016/j.mri.2015.02.010.
[10] Zhang, Run, Fa, Zhiqiang, Liu, Yi, Sun, Haitao, Li, Peng, Li, Shaorui, Wang, Xuxia, Lei, Hao, Jiang, Xiaodan. Dynamic MRI of rat brain following manganese administration through the internal carotid artery. NEUROLOGICAL RESEARCH[J]. 2014, 36(7): 679-686, http://ir.iphy.ac.cn/handle/311004/59397.
[11] Changqian Cao, 王旭霞, Yao Cai, Yongxin Pan. Targeted in vivo imaging of microscopic tumors with ferritin-based nanoprobes across biological barriers. Adv Mater[J]. 2014, [12] Xiao, Yan, Xue, Rong, You, Tianyan, Li, Xiaojing, Pei, Fengkui, Wang, Xuxia, Lei, Hao. Gadolinium-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid conjugate of arabinogalactan as a potential liver-targeting magnetic resonance imaging contrast agent. CARBOHYDRATE RESEARCH[J]. 2014, 395(33): 9-14, http://dx.doi.org/10.1016/j.carres.2014.05.022.
[13] Li, Jianfeng, Huang, Shixian, Shao, Kun, Liu, Yang, An, Sai, Kuang, Yuyang, Guo, Yubo, Ma, Haojun, Wang, Xuxia, Jiang, Chen. A choline derivate-modified nanoprobe for glioma diagnosis using MRI. SCIENTIFIC REPORTS[J]. 2013, 3: http://www.irgrid.ac.cn/handle/1471x/960781.
[14] Hou, Yi, Qiao, Ruirui, Fang, Fang, Wang, Xuxia, Dong, Chengyan, Liu, Kan, Liu, Chunyan, Liu, Zhaofei, Lei, Hao, Wang, Fan, Gao, Mingyuan. NaGdF4 Nanoparticle-Based Molecular Probes for Magnetic Resonance Imaging of Intraperitoneal Tumor Xenografts in Vivo. ACS NANO[J]. 2013, 7(1): 330-338, http://ir.wipm.ac.cn/handle/112942/949.
[15] He, Rui, Xing, Gengmei, Wang, Xuxia, Jiao, Yanhua, Zhao, Hong, Yuan, Hui, Wang, Shukuan, Dong, Jinquan, Lei, Hao. Synthesis and Evaluation of Bingel-Hirsch Multiadducts of Paramagnetic Gadofullerene as Potential Magnetic Resonance Imaging Contrast Agents. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY[J]. 2013, 13(2): 1549-1554, http://ir.ihep.ac.cn/handle/311005/224150.
[16] Yan, Huihui, Wang, Lu, Wang, Jiyao, Weng, Xiaofu, Lei, Hao, Wang, Xuxia, Jiang, Lu, Zhu, Jianhua, Lu, Weiyue, Wei, Xunbin, Li, Cong. Two-Order Targeted Brain Tumor Imaging by Using an Optical/Paramagnetic Nanoprobe across the Blood Brain Barrier. ACS NANO[J]. 2012, 6(1): 410-420, http://ir.wipm.ac.cn/handle/112942/1594.
[17] Mao, Xian, Li, Ning, Mao, Jiezhen, Li, Qiurong, Xiao, Nan, Jiang, Bin, Jiang, Ling, Wang, Xuxia, Liu, Maili. Fast detection of choline-containing metabolites in liver using 2D H-1-N-14 three-bond correlation (HN3BC) spectroscopy. JOURNAL OF MAGNETIC RESONANCE[J]. 2012, 214: 352-359, http://ir.wipm.ac.cn/handle/112942/1688.
[18] Han, Liang, Li, Jianfeng, Huang, Shixian, Huang, Rongqin, Liu, Shuhuan, Hu, Xing, Yi, Peiwei, Shan, Dai, Wang, Xuxia, Lei, Hao, Jiang, Chen. Peptide-conjugated polyamidoamine dendrimer as a nanoscale tumor-targeted T1 magnetic resonance imaging contrast agent. BIOMATERIALS[J]. 2011, 32(11): 2989-2998, http://dx.doi.org/10.1016/j.biomaterials.2011.01.005.
[19] Li,S, Huang,MM, Wang,XH, Wang,XX, Chen,F, Lei,H, Jiang,FG. Retinal Metabolic Changes in an Experimental Model of Optic Nerve Transection by Ex Vivo (1)H Magnetic Resonance Spectroscopy. NEUROCHEMICAL RESEARCH[J]. 2011, 36(12): 2427-2433, http://ir.wipm.ac.cn/handle/112942/1909.
[20] Xu, Wei, Zhan, Yanqiang, Huang, Wei, Wang, Xuxia, Zhang, Sumin, Lei, Hao. Reduction of Hippocampal N-Acetyl Aspartate Level in Aged APP(Swe)/PS1(dE9) Transgenic Mice Is Associated With Degeneration of CA3 Pyramidal Neurons. JOURNAL OF NEUROSCIENCE RESEARCH[J]. 2010, 88(14): 3155-3160, http://www.irgrid.ac.cn/handle/1471x/960538.
[21] Meng, Huan, Xing, Gengmei, Sun, Baoyun, Zhao, Feng, Lei, Hao, Li, Wei, Song, Yan, Chen, Zhen, Yuan, Hui, Wang, Xuxia, Long, Jing, Chen, Chunying, Liang, Xingjie, Zhang, Ning, Chai, Zhifang, Zhao, Yuliang. Potent Angiogenesis Inhibition by the Particulate Form of Fullerene Derivatives. ACS NANO[J]. 2010, 4(5): 2773-2783, http://ir.ihep.ac.cn/handle/311005/239820.
[22] Zhang, Zhi, He, Rui, Yan, Kun, Guo, Qianni, Lu, Yunguo, Wang, Xuxia, Lei, Hao, Li, Zaoying. Synthesis and in vitro and in vivo evaluation of manganese(III) porphyrin-dextran as a novel MRI contrast agent. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2009, 19(23): 6675-6678, http://dx.doi.org/10.1016/j.bmcl.2009.10.003.
[23] Li, Yingxia, Fang, Fang, Wang, Xuxia, Lei, Hao. Neuronal projections from ventral tegmental area to forebrain structures in rat studied by manganese-enhanced magnetic resonance imaging. MAGNETIC RESONANCE IMAGING[J]. 2009, 27(3): 293-299, http://dx.doi.org/10.1016/j.mri.2008.07.011.
[24] Li, Weisheng, Li, Zhongfeng, Jing, Fengying, Deng, Yuefeng, Wei, Lai, Liao, Peiqiu, Yang, Xiangguang, Li, Xiaojing, Pei, Fengkui, Wang, Xuxia, Lei, Hao. Synthesis and evaluation of Gd-DTPA-labeled arabinogalactans as potential MRI contrast agents. CARBOHYDRATE RESEARCH[J]. 2008, 343(4): 685-694, http://dx.doi.org/10.1016/j.carres.2008.01.008.
[25] Li, Zhongfeng, Li, Weisheng, Li, Xiaojing, Pei, Fengkui, Wang, Xuxia, Lei, Hao. Mn(II)-monosubstituted polyoxometalates as candidates for contrast agents in magnetic resonance imaging. JOURNAL OF INORGANIC BIOCHEMISTRY[J]. 2007, 101(7): 1036-1042, http://dx.doi.org/10.1016/j.jinorgbio.2007.04.003.

   

（1） 基于“铁蛋白-髓鞘-轴突”机制的多模态MRI对阿尔茨海默病的早期预测研究，参与，国家级，2012-01--2015-12
（2） 视觉剥夺引起大鼠脑结构可塑性改变的多模态磁共振成像研究，主持，国家级，2011-01--2013-12

（1） 锰中毒引起大鼠苍白球代谢紊乱的磁共振波谱研究，第15届全国波谱学学术会议，2008-10，王旭霞