基本信息

颜一军 男 中国科学院昆明植物研究所
电子邮件: yanyijun@mail.kib.ac.cn
通信地址: 云南省昆明市盘龙区蓝黑路132号
邮政编码:
电子邮件: yanyijun@mail.kib.ac.cn
通信地址: 云南省昆明市盘龙区蓝黑路132号
邮政编码:
教育背景
2007-09--2013-07 东北农业大学 博士2003-09--2007-07 东北农业大学 学士
工作经历
工作简历
2022-02~现在, 中国科学院昆明植物研究所, 研究员2017-01~2022-02,中国科学院昆明植物研究所, 副研究员2013-08~2016-12,中国科学院昆明植物研究所, 博士后
专利与奖励
专利成果
[1] 黄胜雄, 纪旭, 颜一军, 杨静, 罗剑英. 一种罗博卢酮的生物合成基因簇及其应用. CN: CN106636141B, 2019-08-13.[2] 黄胜雄, 纪旭, 颜一军, 杨静, 罗剑英. 一种托酚酮类化合物及其药物组合物和其制备方法与应用. 中国: CN105585573B, 2018-04-17.[3] 黄胜雄, 汪香婷, 杨静, 杨瑞敏, 张秀磊, 颜一军. α‑吡喃酮类化合物及其药物组合物和其在制药中的应用. 中国: CN107266406A, 2017.10.20.
出版信息
发表论文
(1) Characterization of Multifunctional and Non-stereoselective Oxidoreductase RubE7/IstO, Expanding the Functional Diversity of the Flavoenzyme Superfamily, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 第 1 作者(2) Biochemical and Metabolic Insights into Hyoscyamine Dehydrogenase, ACS CATALYSIS, 2021, 第 2 作者(3) Taxonomic Characterization, and Secondary Metabolite Analysis of Streptomyces triticiradicis sp. nov.: A Novel Actinomycete with Antifungal Activity, MICROORGANISMS, 2020, 第 5 作者(4) Characterization of inthomycin biosynthetic gene cluster revealing new insights into carboxamide formation, Characterization of inthomycin biosynthetic gene cluster revealing new insights into carboxamide formation, CHINESE JOURNAL OF NATURAL MEDICINES, 2020, 第 7 作者(5) Benwamycins A-G, Trialkyl-Substituted Benzene Derivatives from a Soil-Derived Streptomyces, JOURNAL OF NATURAL PRODUCTS, 2020, 第 8 作者(6) Biosynthetic access to the rare antiarose sugar via an unusual reductase-epimerase, CHEMICAL SCIENCE, 2020, 第 1 作者(7) Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic streptomyces, ORGANIC CHEMISTRY FRONTIERS, 2019, 第 6 作者(8) Characterization of the N-methyltransferases involved in the biosynthesis of toxoflavin, fervenulin and reumycin from Streptomyces hiroshimensis ATCC53615, ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 第 2 作者(9) A new actinomycin Z analogue with an additional oxygen bridge between chromophore and beta-depsipentapeptide from Streptomyces sp. KIB-H714, NATURAL PRODUCT RESEARCH, 2019, 第 5 作者(10) Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces, JOURNAL OF ORGANIC CHEMISTRY, 2018, 第 2 作者(11) New phenoxazinone-related alkaloids from strain streptomyces sp kib-h1318, JOURNAL OF ANTIBIOTICS, 2018, 第 5 作者(12) Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity, JOURNAL OF ANTIBIOTICS, 2018, 第 8 作者(13) New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318, CANCERS, 2018, 第 6 作者(14) Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity, NATURAL PRODUCT COMMUNICATIONS, 2018, 第 3 作者(15) Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces, ORGANIC CHEMISTRY FRONTIERS, 2018, 第 3 作者(16) Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor, ORGANIC LETTERS, 2017, 第 8 作者(17) Lorneic Acid Analogues from an Endophytic Actinomycete, JOURNAL OF NATURAL PRODUCTS, 2017, 第 8 作者(18) α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells, Nat. Prod. Bioprospect., 2017, 第 6 作者(19) Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids, NATURE COMMUNICATIONS, 2016, 第 1 作者(20) Tropolone Ring Construction in the Biosynthesis of Rubrolone B, a Cationic Tropolone Alkaloid from Endophytic Streptomyces, ORGANIC LETTERS, 2016, 第 1 作者(21) A new antifungal macrolide from Streptomyces sp. KIB-H869 and structure revision of halichomycin, TETRAHEDRON LETTERS, 2016, 第 7 作者(22) 土壤来源链霉菌KIB-H91次级代谢产物的分离鉴定, 天然产物研究与开发, 2015, 第 4 作者(23) Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase, MICROBIAL CELL FACTORIES, 2015, 第 2 作者(24) New Duclauxamide from Penicillium manginii YIM PH30375 and Structure Revision of the Duclauxin Family, ORGANIC LETTERS, 2015, 第 4 作者(25) Neaumycin - A New Macrolide from Streptomyces sp. NEAU-x211, Org. Lett, 2012, 第 3 作者
科研活动
科研项目
( 1 ) 罗博卢酮类天然产物稀有糖基的合成,转移及结构多样性研究, 主持, 国家级, 2021-01--2024-12( 2 ) 三七根际微生物活性天然产物的发现与生物合成, 主持, 部委级, 2020-01--2022-12( 3 ) 基于lipstatin组合生物合成的胰脂肪酶抑制剂的研究, 主持, 省级, 2019-10--2022-09( 4 ) 云南省“****”青年人才入选者科研项目支持经费, 主持, 省级, 2019-01--2023-12( 5 ) 青年创新促进会支持经费, 主持, 部委级, 2018-01--2021-12