070302-分析化学

超灵敏磁共振分子探针与分子影像

2012-09--2017-06   中国科学院大学   博士学位
2008-09--2012-06   华中师范大学   学士学位

   

2020-12~现在, 中国科学院精密测量科学与技术创新研究院, 副研究员
2017-07~2020-11,中国科学院精密测量科学与技术创新研究院, 博士后

   

（1） 中国分析测试协会科学技术奖青年奖, 其他, 2017

[1] 周欣, 曾庆斌, 郭茜旎, 王珍, 孙献平. 一种多组分金属有机框架材料及其应用. CN202111651962.X, 2021-12-30.

[2] 周欣, 乐曲儿, 曾庆斌, 郭茜旎, 孙献平. 一种硫化铜与金属有机框架复合纳米材料的应用. CN202111613615.8, 2021-12-27.

[3] 周欣, 曾庆斌, 郭茜旎, 袁亚平, 孙献平, 刘买利. 一种多功能穴番-卟啉化合物及其合成方法和应用. CN: CN107880061B, 2019-11-01.

[4] 周欣, 曾庆斌, 郭茜旎, 孙献平, 刘买利. 一种沸石咪唑骨架材料在磁共振成像中的应用. 中国: CN108578715A, 2018-09-28.

   

[1] Zeng, Qingbin, Guo, Qianni, Yuan, Yaping, Wang, Baolong, Sui, Meiju, Lou, Xin, Bouchard, Louis-S., Zhou, Xin. Ultrasensitive molecular building block for biothiol NMR detection at picomolar concentrations. iScience[J]. 2021, 24(12): 103515-, https://www.sciencedirect.com/science/article/pii/S2589004221014863?via%3Dihub.
[2] Zhao, Longhui, Guo, Qianni, Yuan, Chenlu, Li, Sha, Yuan, Yaping, Zeng, Qingbin, Zhang, Xu, Ye, Chaohui, Zhou, Xin. Photosensitive MRI biosensor for BCRP-Targeted uptake and light-induced inhibition of tumor cells. Talanta[J]. 2021, 233: 122501-, https://www.sciencedirect.com/science/article/pii/S0039914021004227?via%3Dihub.
[3] Zeng, Qingbin, Bie, Binglin, Guo, Qianni, Yuan, Yaping, Han, Qi, Han, Xiaocang, Chen, Mingwei, Zhang, Xu, Yang, Yunhuang, Liu, Maili, Liu, Pan, Deng, Hexiang, Zhou, Xin. Hyperpolarized Xe NMR signal advancement by metal-organic framework entrapment in aqueous solution. Proceedings of the National Academy of Sciences of the United States of America[J]. 2020, 117(30): 17558-17563, https://www.pnas.org/doi/10.1073/pnas.2004121117.
[4] Zeng, Qingbin, Guo, Qianni, Yuan, Yaping, Zhang, Xiaoxiao, Jiang, Weiping, Xiao, Sa, Zhang, Bin, Lou, Xin, Ye, Chaohui, Liu, Maili, Bouchard, Louis-S., Zhou, Xin. A Small Molecular Multifunctional Tool for pH Detection, Fluorescence Imaging, and Photodynamic Therapy. ACS APPLIED BIO MATERIALS[J]. 2020, 3(3): 1779-1786, https://pubs.acs.org/doi/10.1021/acsabm.9b01080.
[5] Ren, Lili, Chen, Shizhen, Jiang, Weiping, Zeng, Qingbin, Zhang, Xu, Xiao, Long, McMahon, Michael T, Xin, Lou, Zhou, Xin. Efficient temperature-feedback liposome for F-19 MRI signal enhancement. CHEMICAL COMMUNICATIONS[J]. 2020, 56(92): 14427-14430, http://xlink.rsc.org/?DOI=D0CC05809B.
[6] Zhang, Xiaoxiao, Yuan, Yaping, Li, Sha, Zeng, Qingbin, Guo, Qianni, Liu, Na, Yang, Minghui, Yang, Yunhuang, Liu, Maili, McMahon, Michael T, Zhou, Xin. Free-base porphyrins as CEST MRI contrast agents with highly upfield shifted labile protons. MAGNETIC RESONANCE IN MEDICINE[J]. 2019, 82(2): 577-585, https://www.webofscience.com/wos/woscc/full-record/WOS:000471308300006.
[7] Zhang, Bin, Guo, Qianni, Luo, Qing, Zhang, Xiaoxiao, Zeng, QingBin, Zhao, Longhui, Yuan, Yaping, Jiang, Weiping, Yang, Yunhuang, Liu, Maili, Ye, Chaohui, Zhou, Xin. An intracellular diamine oxidase triggered hyperpolarized Xe-129 magnetic resonance biosensor. CHEMICAL COMMUNICATIONS[J]. 2018, 54(97): http://xlink.rsc.org/?DOI=C8CC07822J.
[8] Yang, Shengjun, Zeng, Qingbin, Guo, Qianni, Chen, Shizhen, Liu, Hongbin, Liu, Maili, McMahon, Michael T, Zhou, Xin. Detection and differentiation of Cys, Hcy and GSH mixtures by F-19 NMR probe. TALANTA[J]. 2018, 184: 513-519, https://www.webofscience.com/wos/woscc/full-record/WOS:000432234900066.
[9] Zeng, Qingbin, Guo, Qianni, Yuan, Yaping, Yang, Yuqi, Zhang, Bin, Ren, Lili, Zhang, Xiaoxiao, Luo, Qing, Liu, Maili, Bouchard, LouisS, Zhou, Xin. Mitochondria Targeted and Intracellular Biothiol Triggered Hyperpolarized Xe-129 Magnetofluorescent Biosensor. ANALYTICAL CHEMISTRY[J]. 2017, 89(4): 2288-2295, https://pubs.acs.org/doi/10.1021/acs.analchem.6b03742.
[10] Yang, Yuqi, Chen, Shizhen, Liu, Lianhua, Li, Sha, Zeng, Qingbin, Zhao, Xiuchao, Li, Haidong, Zhang, Zhiying, Bouchard, Louis-S., Liu, Maili, Zhou, Xin. Increasing Cancer Therapy Efficiency through Targeting and Localized Light Activation. ACS APPLIED MATERIALS & INTERFACES[J]. 2017, 9(28): 23400-23408, https://www.webofscience.com/wos/woscc/full-record/WOS:000406172700014.
[11] Guo, Qianni, Zeng, Qingbin, Jiang, Weiping, Luo, Qing, Zhang, Xu, Bouchard, Louis-S., Liu, Maili, Zhou, Xin. A Molecular Imaging Approach to Mercury Sensing Based on Hyperpolarized 129Xe Molecular Clamp Probe. Chemistry – A European Journal[J]. 2016, 22(12): 3967-3970, http://dx.doi.org/10.1002/chem.201600193.
[12] Guo, Qianni, Zeng, Qingbin, Zhang, Xiaoxiao, Zhou, Xin. Highly sensitive detection of mercury (II) in aqueous media by tetraphenylporphyrin with a metal ion receptor. SUPRAMOLECULAR CHEMISTRY[J]. 2014, 26(10-12): 836-842, http://ir.wipm.ac.cn/handle/112942/1398.
[13] 曾庆斌, 郭茜旎, 罗晴, 吴光耀, 周欣. 锰对比剂在MRI中的应用. 磁共振成像[J]. 2014, 5(4): 315-320, http://lib.cqvip.com/Qikan/Article/Detail?id=661908143.

   

（ 1 ） 荧光标记MOF用于非小细胞肺癌的超灵敏磁共振分子影像传感, 主持, 国家级, 2021-01--2023-12
（ 2 ） 外泌体介导的129Xe/19F双核MRI用于肺癌早期探测及其演进机制的研究, 参与, 国家级, 2019-01--2022-12
（ 3 ） 肺的异构功能性数据获取与智能融合, 参与, 部委级, 2019-09--2029-08
（ 4 ） 肺癌的超高灵敏谱学与成像新技术研究, 参与, 国家级, 2019-09--2024-08