071005-微生物学
100103-病原生物学

抗病毒免疫
病毒学

1985-09--1989-06   纽约州立大学布法罗分校   免疫学博士
1978-09--1983-06   上海第二医学院   医学学士

   

2005-07~现在, 中国科学院上海巴斯德研究所, 研究员
2001-01~2005-07,Southwest National Primate Center, Affiliate Member
1999-10~2005-07,University of Texas Health Science Center at San A, 兼职副教授
1998-10~2005-07,Southwest Foundation for Biomedical Research, 研究员
1993-06~1998-09,美国国立卫生研究院, Senior Staff Fellow
1989-02~1993-05,Mayo Clinic, 博士后
1985-09~1989-06,纽约州立大学布法罗分校, 免疫学博士
1978-09~1983-06,上海第二医学院, 医学学士

高级免疫学与病毒学系列讲座
Viral Immunolog

   

（1） 朱李月华优秀教师, , 研究所（学校）, 2010

（ 1 ） 人源抗高治病禽流感中和抗体（65C6）, 2011, 第 1 作者, 专利号: 201110295786.0

（ 2 ） 一种稳转果蝇S2细胞生产病毒样颗粒的方法及应用, 2011, 第 1 作者, 专利号: 201110065251.4

   

（1） Trimeric GPI-CDR H3 of broadly neutralizing antibody PG16 is a potent HIV-1 entry inhibitor, J. Virol , 2013, 通讯作者
（2） Unravel a neutralization mechanism by two human antibodies against conserved epitopes in the globular head of H5 hemagglutinin, J. Virol , 2013, 通讯作者
（3） A Human Antibody Recognizing a Conserved Epitope of H5 Hemagglutinin Broadly Neutralizes Highly Pathogenic Avian Influenza H5N1 Viruses, J. Virol, 2012, 通讯作者
（4） A tri-clade DNA vaccine designed on the basis of a comprehensive serologic study elicits neutralizing antibody responses against all clades and subclades of HPAI H5N1 viruses, J. Virol, 2012, 通讯作者
（5） HIV-1 virus like particles produced by stably transfected Drosophila S2 cells - a desirable vaccine component, J. Virol., 2012, 通讯作者
（6） High Yield of Human Monoclonal Antibody Produced by Stably Transfected Drosophila Schneider 2 Cells in Perfusion Culture Using Wave Bioreactor, Mol Biotechnol, 2011, 通讯作者
（7） Production of hepatitis C virus lacking the envelope-encoding genes for single-cycle infection by providing homologous envelope proteins or vesicular stomatitis virus glycoproteins in trans, J. Virol, 2011, 通讯作者
（8） Vif Substitution Enables Persistent Infection of Pig-tailed 1 Macaques By Human Immunodeficiency virus type, J. Virol, 2011, 通讯作者
（9） Superior Neutralizing Antibody Response and Protection in Mice Vaccinated with Heterologous DNA Prime and Virus Like Particle Boost against HPAI H5N1 Virus, PLoS ONE , 2011, 通讯作者
（10） Heterosubtypic Antibody Response Elicited with Seasonal Influenza Vaccine Correlates Partial Protection against Highly Pathogenic H5N1 Virus, PLoS ONE, 2011, 通讯作者
（11） Potent and broad anti-HIV-1 activity exhibited by a GPI-anchored peptide derived from the CDR H3 of broadly neutralizing antibody PG16, J. Virol, 2011, 通讯作者
（12） GPI-anchored single chain Fv - an effective 1 way to capture transiently-exposed neutralization epitopes on HIV-1 envelope spike, Retrovirology, 2010, 通讯作者
（13） Measure neutralizing antibody responses against HPAI H5N1 viruses using influenza HA and NA pseudotype-based assay, Vaccine , 2009, 通讯作者
（14） A non-neutralizing anti-HIV-1 antibody turns into a broad neutralizing antibody when expressed on the surface of HIV-1-susceptible cells (II): inhibition of HIV-1 captured and transferred by DC-SIGN, AIDS Res. And Hum. Retroviruses , 2006, 通讯作者
（15） A non-neutralizing anti-HIV-1 antibody turns into a neutralizing antibody by expressing it on the surface of HIV-1-susceptible cells – a new way to fight HIV-1, J. Immunol., 2004, 通讯作者
（16） Inhibition of HIV-1 replication in human primary T cells transduced with intracellular anti-HIV-1 p17 antibody targeted into cytosolic compartment, J. Gene Med, 2003, 通讯作者
（17） Inhibition of HIV-1 replication by the synergistic action of anti-gp41 single chain antibody and IL-16, Antiviral Research, 2003, 第 2 作者
（18） High efficiency gene transfer into rhesus macaque primary T lymphocytes by combining 320C centrifugation and CH-296-coated plates: effect of ex vivo gene transfer protocol on lymphocyte homing receptor expression., Hum. Gene Ther, 2001, 第 1 作者
（19） Processing, secretion and anti-HIV-1 activity of interleukin-16 with or without a signal peptide in CD4+ T cells, J. Immunol, 1999, 第 1 作者
（20） Cells transfected with a non-neutralizing antibody gene are resistant to HIV infection: targeting in the endoplasmic reticulum and trans-golgi network, J. Immunol, 1998, 第 1 作者
（21） Inhibition of HIV-1 by anti-HIV-1 p17 (matrix) scFv/Ck expressed in cytosol and nucleus, J. Immunol, 1998, 通讯作者
（22） Human CD4 cells transfected with IL-16 cDNA are resistant to HIV-1 infection: inhibition of mRNA expression, Nature Medicine, 1997, 第 1 作者
（23） HLA-DQB1 polymorphism determines incidence, onset, and severity of collagen-induced arthritis (CIA) in transgenic mice: implications in human rheumatoid arthritis, J. Clin. Invest, 1997, 第 4 作者
（24） Human leukocyte antigen-DRB1*1502 (DR2Dw12) transgene reduces incidence and severity of arthritis in mice, Hum. Immunol., 1996, 第 4 作者
（25） Retrovirus-induced lymphoproliferative disease in mice undergoing graft-versus-host reaction,  Immunol. Invest, 1995, 第 3 作者
（26） Genetic polymorphism of the mouse major histocompatibility complex-associated proteasome subunit Lmp-7, Immunogenetics, 1995, 第 2 作者
（27） Retrovirus-induced lymphoproliferative disease in mice: role of humoral immunity in perinatally exposed mice, Immunobiology , 1995, 第 3 作者
（28） Blood transfusion as a means for transmission of retrovirus-induced lymphoproliferative disease in mice, Int. Arch. Allerg. Immunol, 1994, 第 3 作者
（29） Acquired immunodeficiency in murine lymphoproliferative disease: considerations of pathogenesis, Immunobiology , 1994, 第 3 作者
（30） Expression of T cell receptor Vb transcripts in central nervous system of mice susceptible and resistant to Theiler’s virus-induced demyelination, J. Neuroimmunol, 1993, 第 3 作者
（31） Genomic organization and tissue expression of mouse Lmp-7 gene, Immunogenetics, 1993, 第 2 作者
（32） Genomic organization and tissue expression of mouse proteasome gene Lmp-2, Genomics, 1993, 第 1 作者
（33） Molecular basis of genetic polymorphism of proteasome gene Lmp-2, Proc. Natl. Acad. Sci. USA, 1993, 第 1 作者
（34） HLA-DQb chain can present mouse endogenous provirus MTV-9 product and clonally delete TCR Vb5 and Vb11 T cells in transgenic mice, Immunogenetics, 1992, 第 1 作者
（35） Postnatal development of murine spleen cell proliferative responses induced by interleukin 2 or phorbol ester and calcium ionophore A 23187, Immunobiology, 1991, 第 2 作者
（36） Alteration of mouse T cell receptor repertoire by Aa/DQb hybrid molecules in DQb single transgenic mice, Transplant. Proc, 1991, 第 1 作者
（37） Thymic deletion of Vb11 and Vb5 T cells in H-2E negative, HLA DQb+ transgenic mice, J. Immunol, 1991, 第 1 作者
（38） HLA-DQb present mouse Mls and clonally deletes Vb6 and Vb8.1 bearing T cells in DQb single transgenic mice, Human Immunol, 1991, 第 1 作者
（39） Generation of transgenic mice bearing human class II genes, Miami Bio/Technology Winter Symposia, 1990, 第 1 作者
（40） Factors affecting proliferation on non-immune murine T cells in vitro, Transplant. Proc, 1989, 第 1 作者
（41） In vitro proliferation of murine spleen cells: strain variation of responses to medium from cultures of EL-4 cells, Immunol. Invest, 1989, 第 2 作者
（42） In vitro proliferation of murine spleen cells: inhibition by monoclonal antibodies to L3T4 and Lyt-2 T cell markers and intracellular cAMP, Exp. Cell. Biol, 1989, 第 1 作者
（43） In vitro proliferativ response of murine spleen cells: strain variation of proliferative reponse induced by recombinant IL-2, Int. Arch. Allergy Immunol., 1989, 第 1 作者
（44） In vitro response induced by phorbol ester and calcium ionophore A23187, Immunobiology , 1989, 第 1 作者
（45） Evidence that class I-restricted response to Thy-1 antigen requires L3T4 cells and macrophages but not Lyt-2 cells, Transplantation , 1989, 第 1 作者
（46） Macrophage I-A hybrid molecules as product of Ir-Thy-1 genes. , H-2 Antigens, Genes, Molecules, Functions, 1987, 第 1 作者
（47） Anti-Thy-1 response of H-2f/H-2r heterozygotes: an unusual case of genetic control, Immunol. Invest, 1986, 第 3 作者

（ 1 ） 主要组织相容性复合物，超抗原和T细胞受体的共进化, Co-evolution of MHC, Superantigens and T Cell Receptors, Academic Press , 1991-07, 第 1 作者

   

（ 1 ） 用基因编码的中和抗体阻断艾滋病毒的感染, 负责人, 国家任务, 2012-01--2014-12
（ 2 ） 开发完全保护原代CD4 T细胞不被HIV-1感染的新策略, 负责人, 国家任务, 2012-01--2015-12
（ 3 ） 病毒样颗粒研究, 参与, 国家任务, 2012-01--2015-12
（ 4 ） 抗H5N1人源化抗体研究, 负责人, 其他国际合作项目, 2011-09--2014-08
（ 5 ） 抗HIV的GPI锚定抗体衍生物, 负责人, 国家任务, 2013-01--2013-12