040222-行为遗传学
040220-医学心理学
071021-生物信息学

生物信息学，遗传学
生物信息学，遗传学

2005-12--2008-10   瑞士洛桑大学医学中心（CHUV,UNIL）、瑞士洛桑联邦理工大学(EPFL)   博士后
2000-09--2005-06   北京大学生命科学学院   博士
1996-09--2000-06   北京大学数学科学学院   学士

   

2008-11~现在, 中国科学院心理研究所, 助理研究员、副研究员

   

[1] 张萦倩, 赵光义, 韩雨薇, 张静怡, 曹成琦, 王力, 张昆林. 创伤后应激障碍的组蛋白修饰机制. 心理科学进展[J]. 2022, 30(1): 98-114, http://lib.cqvip.com/Qikan/Article/Detail?id=7106386259.
[2] 左玲, 陈建新, 王伟, 汪思佳, 张昆林. 中医信息学与表型组学：症状的遗传突变与证候的生物学基础初探. 北京中医药大学学报[J]. 2022, 45(2): 140-147, http://bjvip.las.ac.cn/qk/93826A/202202/7106746071.html.
[3] Zhang, Jingyi, Li, Gen, Yang, Haibo, Cao, Chengqi, Fang, Ruojiao, Liu, Ping, Luo, Shu, Zhao, Guangyi, Zhang, Yingqian, Zhang, Kunlin, Wang, Li. The main effect and gene-environment interaction effect of the ADCYAP1R1 polymorphism rs2267735 on the course of posttraumatic stress disorder symptoms—A longitudinal analysis. Frontiers in Psychiatry[J]. 2022, 13: 1032837-, https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1032837/full.
[4] Shi, Leisheng, Wang, Yan, Li, Chong, Zhang, Kunlin, Du, Quansheng, Zhao, Mei. AddictGene: An integrated knowledge base for differentially expressed genes associated with addictive substance. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL[J]. 2021, 19: 2416-2422, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000692620700011.
[5] 张静怡, 赵光义, 张萦倩, 张昆林. 创伤后应激障碍相关精神障碍与自身免疫疾病的遗传关联. 第二十三届全国心理学学术会议摘要集（下）null. 2021, 1-, [6] Wang, Li, Zhang, Jingyi, Li, Gen, Cao, Chengqi, Fang, Ruojiao, Liu, Ping, Luo, Shu, Zhao, Guangyi, Zhang, Yingqian, Zhang, Kunlin. The ADCYAP1R1 Gene Is Correlated With Posttraumatic Stress Disorder Symptoms Through Diverse Epistases in a Traumatized Chinese Population. FRONTIERS IN PSYCHIATRY[J]. 2021, 12: [7] 张昆林, 孙鹏程, 陈雪梅, 陈建新, 张妍, 王一, 王济, 王琦. 基于生物信息学方法的祛风解表中药干预过敏体质机制研究. 天津中医药[J]. 2021, 38(3): 273-279, http://lib.cqvip.com/Qikan/Article/Detail?id=7104060876.
[8] Gao, Jian, Zhang, Kunlin, Wang, Yi, Guo, Rui, Liu, Hao, Jia, Caixia, Sun, Xiaoli, Wu, Chaoyong, Wang, Wei, Du, Jie, Chen, Jianxin. A machine learning-driven study indicates emodin improves cardiac hypertrophy by modulation of mitochondrial SIRT3 signaling. PHARMACOLOGICAL RESEARCH[J]. 2020, 155: http://dx.doi.org/10.1016/j.phrs.2020.104739.
[9] Zhang, Kunlin, Wang, Li, Li, Gen, Cao, Chengqi, Fang, Ruojiao, Liu, Ping, Luo, Shu, Zhang, Xiangyang. Correlation between hypothalamic-pituitary-adrenal axis gene polymorphisms and posttraumatic stress disorder symptoms. HORMONES AND BEHAVIOR[J]. 2020, 117: 8-, http://dx.doi.org/10.1016/j.yhbeh.2019.104604.
[10] Liu, Xuewei, Jia, Caixia, Wu, Chuanhong, Wang, Na, Jia, Yongming, Zhu, Yongtao, Li, Pengyue, Ghulam, Murtaza, Zhang, Kunlin. Discovering Traditional Chinese Medicinal Herbs for Neurodegenerative Disorders. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES[J]. 2020, 82: 70-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000566973300014.
[11] Zhang, Kunlin, Fan, Zili, Wang, Yufeng, Faraone, Stephen, V, Yan, Li, Chang, Suhua. Genetic analysis for cognitive flexibility in the trail-making test in attention deficit hyperactivity disorder patients from single nucleotide polymorphism, gene to pathway level. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY[J]. 2019, 20(6): 476-485, http://dx.doi.org/10.1080/15622975.2017.1386324.
[12] Zhao, Mei, Hou, Lingling, Teng, Huajing, Li, Jinchen, Wang, Jiesi, Zhang, Kunlin, Yang, Lin. Whole-Exome Sequencing Identified a Novel Compound Heterozygous Genotype in ASL in a Chinese Han Patient with Argininosuccinate Lyase Deficiency. BIOMED RESEARCH INTERNATIONAL[J]. 2019, 2019: http://dx.doi.org/10.1155/2019/3530198.
[13] Li, Gen, Zhang, Kunlin, Wang, Li, Cao, Chengqi, Fang, Ruojiao, Liu, Ping, Luo, Shu, Liberzon, Israel. The preliminary investigation of orexigenic hormone gene polymorphisms on posttraumatic stress disorder symptoms. PSYCHONEUROENDOCRINOLOGY[J]. 2019, 100: 131-136, http://dx.doi.org/10.1016/j.psyneuen.2018.09.042.
[14] Zhang, Kunlin, Li, Gen, Wang, Li, Cao, Chengqi, Fang, Ruojiao, Luo, Shu, Liu, Ping, Zhang, Xiang Yang. An epistasis between dopaminergic and oxytocinergic systems confers risk of post-traumatic stress disorder in a traumatized Chinese cohort. SCIENTIFIC REPORTS[J]. 2019, 9(1): http://dx.doi.org/10.1038/s41598-019-55936-8.
[15] Zhang, Kunlin, Wang, Li, Cao, Chengqi, Li, Gen, Fang, Ruojiao, Liu, Ping, Luo, Shu, Zhang, Xiangyang, Liberzon, Israel. A DRD2/ANNK1-COMT Interaction, Consisting of Functional Variants, Confers Risk of Post-traumatic Stress Disorder in Traumatized Chinese. FRONTIERS IN PSYCHIATRY[J]. 2018, 9: http://dx.doi.org/10.3389/fpsyt.2018.00170.
[16] Susu Qu, Yang Du, Suhua Chang, Liyuan Guo, Kechi Fang, Yongzhe Li, Fengchun Zhang, Kunlin Zhang, Jing Wang. Common variants near IKZF1 are associated with primary Sjögren's syndrome in Han Chinese.. PLOS ONE[J]. 2017, 12(5): https://doaj.org/article/b0b3ac5c85384ff18121824df4769796.
[17] Zhang, Kunlin, Qu, Susu, Chang, Suhua, Li, Gen, Cao, Chengqi, Fang, Kechi, Olff, Miranda, Wang, Li, Wang, Jing. An overview of posttraumatic stress disorder genetic studies by analyzing and integrating genetic data into genetic database PTSDgene. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWSnull. 2017, 83: 647-656, http://dx.doi.org/10.1016/j.neubiorev.2017.08.021.
[18] Wang, Jinglu, Qu, Susu, Wang, Weixiao, Guo, Liyuan, Zhang, Kunlin, Chang, Suhua, Wang, Jing, S Chang, J Wang. A combined analysis of genome-wide expression profiling of bipolar disorder in human prefrontal cortex. JOURNAL OF PSYCHIATRIC RESEARCH[J]. 2016, 82: 23-29, http://dx.doi.org/10.1016/j.jpsychires.2016.07.016.
[19] Yu Xue, Eric-Wubbo Lameijer, Kai Ye, Kunlin Zhang, Suhua Chang, Xiaoyue Wang, Jianmin Wu, Ge Gao, Fangqing Zhao, Jian Li, Chunsheng Han, Shuhua Xu, Jingfa Xiao, Xuerui Yang, Xiaomin Ying, Xuegong Zhang, Wei-Hua Chen, Yun Liu, Zhang Zhang, Kun Huang, Jun Yu. Precision Medicine: What Challenges Are We Facing?. 基因组蛋白质组与生物信息学报：英文版[J]. 2016, 14(5): 253-261, http://lib.cqvip.com/Qikan/Article/Detail?id=670500851.
[20] Piao, Wei, Guo, Jin, Bao, Yihua, Wang, Fang, Zhang, Ting, Huo, Junsheng, Zhang, Kunlin. Analysis of polymorphisms of genes associated with folate-mediated one-carbon metabolism and neural tube defects in Chinese Han Population. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY[J]. 2016, 106(4): 232-239, http://www.irgrid.ac.cn/handle/1471x/1086156.
[21] Zhang, Kunlin, Chang, Suhua, Guo, Liyuan, Wang, Jing. I-GSEA4GWAS v2: a web server for functional analysis of SNPs in trait-associated pathways identified from genome-wide association study. PROTEIN & CELL[J]. 2015, 6(3): 221-224, http://dx.doi.org/10.1007/s13238-014-0114-4.
[22] Fang, Kechi, Zhang, Kunlin, Wang, Jing. Network-assisted analysis of primary Sjogren's syndrome GWAS data in Han Chinese. SCIENTIFIC REPORTS[J]. 2015, 5: http://dx.doi.org/10.1038/srep18855.
[23] Chang, Suhua, Fang, Kechi, Zhang, Kunlin, Wang, Jing. Network-Based Analysis of Schizophrenia Genome-Wide Association Data to Detect the Joint Functional Association Signals. PLOS ONE[J]. 2015, 10(7): http://dx.doi.org/10.1371/journal.pone.0133404.
[24] Chang, Suhua, Wang, Jinglu, Zhang, Kunlin, Wang, Jing. Pathway-based analysis for genome-wide association study data of bipolar disorder provides new insights for genetic study. PROTEIN & CELL[J]. 2015, 6(12): 912-915, http://dx.doi.org/10.1007/s13238-015-0201-1.
[25] 张昆林, 王晶. 心理疾患的遗传学研究. 应激与心理健康——第四届心理健康学术年会null. 2014, http://www.chinair.org.cn/handle/1471x/1667437.
[26] Guo, Liyuan, Du, Yang, Chang, Suhua, Zhang, Kunlin, Wang, Jing. rSNPBase: a database for curated regulatory SNPs. NUCLEIC ACIDS RESEARCH[J]. 2014, 42(D1): D1033-D1039, http://dx.doi.org/10.1093/nar/gkt1167.
[27] Li, Yongzhe, Zhang, Kunlin, Chen, Hua, Sun, Fei, Xu, Juanjuan, Wu, Ziyan, Li, Ping, Zhang, Liuyan, Du, Yang, Luan, Haixia, Li, Xi, Wu, Lijun, Li, Hongbin, Wu, Huaxiang, Li, Xiangpei, Li, Xiaomei, Zhang, Xiao, Gong, Lu, Dai, Lie, Sun, Lingyun, Zuo, Xiaoxia, Xu, Jianhua, Gong, Huiping, Li, Zhijun, Tong, Shengquan, Wu, Min, Li, Xiaofeng, Xiao, Weiguo, Wang, Guochun, Zhu, Ping, Shen, Min, Liu, Shengyun, Zhao, Dongbao, Liu, Wei, Wang, Yi, Huang, Cibo, Jiang, Quan, Liu, Guijian, Liu, Bin, Hu, Shaoxian, Zhang, Wen, Zhang, Zhuoli, You, Xin, Li, Mengtao, Hao, Weixin, Zhao, Cheng, Leng, Xiaomei, Bi, Liqi, Wang, Yongfu, Zhang, Fengxiao, Shi, Qun, Qi, Wencheng, Zhang, Xuewu, Jia, Yuan, Su, Jinmei, Li, Qin, Hou, Yong, Wu, Qingjun, Xu, Dong, Zheng, Wenjie, Zhang, Miaojia, Wang, Qian, Fei, Yunyun, Zhang, Xuan, Li, Jing, Jiang, Ying, Tian, Xinping, Zhao, Lidan, Wang, Li, Zhou, Bin, Li, Yang, Zhao, Yan, Zeng, Xiaofeng, Ott, Jurg, Wang, Jing, Zhang, Fengchun. A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjogren's syndrome at 7q11.23. NATURE GENETICS[J]. 2013, 45(11): 1361-+, http://dx.doi.org/10.1038/ng.2779.
[28] Zhang, WeiNa, Chang, SuHua, Guo, LiYuan, Zhang, KunLin, Wang, Jing, Wang, J reprint author, Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing , Peoples R China. The neural correlates of reward-related processing in major depressive disorder: A meta-analysis of functional magnetic resonance imaging studies. JOURNAL OF AFFECTIVE DISORDERS[J]. 2013, 151(2): 531-539, http://dx.doi.org/10.1016/j.jad.2013.06.039.
[29] Zhang, Liuyan, Chang, Suhua, Li, Zhao, Zhang, Kunlin, Du, Yang, Ott, Jurg, Wang, Jing, Wang, J reprint author, Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing , Peoples R China. ADHDgene: a genetic database for attention deficit hyperactivity disorder. NUCLEIC ACIDS RESEARCH[J]. 2012, 40(D1): D1003-D1009, http://dx.doi.org/10.1093/nar/gkr992.
[30] Fang, Kechi, Zhao, Hansheng, Sun, Changyue, Lam, Carolyn M C, Chang, Suhua, Zhang, Kunlin, Panda, Gurudutta, Godinho, Miguel, dos Santos, Vitor A P Martins, Wang, Jing. Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction. BMC SYSTEMS BIOLOGY[J]. 2011, 5(1): 83-83, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201706299352879ZK.
[31] ZHANG KunLin, ZHANG LiuYan, ZHANG WeiNa, WANG Jing. Pathway-based analysis for genome-wide association studies of schizophrenia to provide new insight in schizophrenia study. 中国科学通报：英文版[J]. 2011, 56(32): 3398-3402, http://lib.cqvip.com/Qikan/Article/Detail?id=39861003.
[32] Zhang, Kunlin, Chang, Suhua, Cui, Sijia, Guo, Liyuan, Zhang, Liuyan, Wang, Jing, Wang, J reprint author, Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing , Peoples R China. ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework. NUCLEIC ACIDS RESEARCH[J]. 2011, 39(Web Server issue): W437-W443, http://dx.doi.org/10.1093/nar/gkr391.
[33] Yang, Liu, Zhang, Kunlin, Dai, Wei, He, Ximiao, Zhao, Qian, Wang, Jing, Sun, Zhong Sheng, Wang, J reprint author, Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing , Peoples R China. Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array. BMC GENOMICS[J]. 2011, 12(1): http://dx.doi.org/10.1186/1471-2164-12-10.
[34] Zhang KunLin, Zhang LiuYan, Zhang WeiNa, Wang Jing, Wang, J reprint author, Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing , Peoples R China. Pathway-based analysis for genome-wide association studies of schizophrenia to provide new insight in schizophrenia study. CHINESE SCIENCE BULLETIN[J]. 2011, 56(32): 3398-3402, http://dx.doi.org/10.1007/s11434-011-4742-2.
[35] Zhang, Kunlin, Cui, Sijia, Chang, Suhua, Zhang, Liuyan, 王晶. i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study. NUCLEIC ACIDS RESEARCH[J]. 2010, 38(Suppl 2): W90-W95, https://www.webofscience.com/wos/woscc/full-record/WOS:000284148900016.
[36] Fellay, Jacques, Ge, Dongliang, Shianna, Kevin V, Colombo, Sara, Ledergerber, Bruno, Cirulli, Elizabeth T, Urban, Thomas J, Zhang, Kunlin, Gumbs, Curtis E, Smith, Jason P, Castagna, Antonella, CozziLepri, Alessandro, De Luca, Andrea, Easterbrook, Philippa, Guenthard, Huldrych F, Mallal, Simon, Mussini, Cristina, Dalmau, Judith, MartinezPicado, Javier, Miro, Jose M, Obel, Niels, Wolinsky, Steven M, Martinson, Jeremy J, Detels, Roger, Margolick, Joseph B, Jacobson, Lisa P, Descombes, Patrick, Antonarakis, Stylianos E, Beckmann, Jacques S, OBrien, Stephen J, Letvin, Norman L, McMichael, Andrew J, Haynes, Barton F, Carrington, Mary, Feng, Sheng, Telenti, Amalio, Goldstein, David B, NIAID Ctr HIV AIDS Vaccine Immunol. Common Genetic Variation and the Control of HIV-1 in Humans. PLOS GENETICS[J]. 2009, 5(12): http://dx.doi.org/10.1371/journal.pgen.1000791.
[37] Zhang, KunLin, Mangeat, Bastien, Ortiz, Millan, Zoete, Vincent, Trono, Didier, Telenti, Amalio, Michielin, Olivier. Model Structure of Human APOBEC3G. PLOS ONE[J]. 2007, 2(4): http://dx.doi.org/10.1371/journal.pone.0000378.

   

（ 1 ） 基于全基因组关联研究数据二次分析的肿瘤候选基因变异研究, 主持, 国家级, 2012-01--2014-12
（ 2 ） 基于芯片的健康评估系统, 主持, 院级, 2016-10--2018-03