071007-遗传学
071004-水生生物学
090801-水产养殖

鱼类抗病育种
病毒致病机制

2008-09--2013-06   中国科学院水生生物研究所   理学博士
2004-09--2008-06   中国地质大学（武汉）   理学学士

   

2017-12~现在, 中国科学院水生生物研究所, 副研究员
2013-07~2017-12,中国科学院水生生物研究所, 助理研究员
2008-09~2013-06,中国科学院水生生物研究所, 理学博士
2004-09~2008-06,中国地质大学（武汉）, 理学学士

   

（1） Grass Carp Prx 3 Elevates Host Antioxidant Activity and Induces Autophagy to Inhibit Grass Carp Reovirus (GCRV) Replication, ANTIOXIDANTS, 2022, 通讯作者
（2） Autophagy signaling pathway is a therapeutic target to inhibit GCRV replication, AQUACULTURE, 2022, 通讯作者
（3） Grass Carp Reovirus Induces Formation of Lipid Droplets as Sites for Its Replication and Assembly, MBIO, 2022, 通讯作者
（4） Genome-wide DNA methylation reveals potential epigenetic mechanism of age-dependent viral susceptibility in grass carp, IMMUNITY & AGEING : I & A, 2022, 通讯作者
（5） Molecular characterization and functional analysis of peroxiredoxin 4 in grass carp (Ctenopharyngodon idella), DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2021, 通讯作者
（6） Multi-Omics Sequencing Provides Insights Into Age-Dependent Susceptibility of Grass Carp (Ctenopharyngodon idellus) to Reovirus, FRONTIERS IN IMMUNOLOGY, 2021, 第 1 作者
（7） Characterization and expression of galectin-3 in grass carp (Ctenopharyngodon idella), DEVELOPMENTALANDCOMPARATIVEIMMUNOLOGY, 2020, 通讯作者
（8） Autophagy Inhibits Grass Carp Reovirus (GCRV) Replication and Protects Ctenopharyngodon idella Kidney (CIK) Cells from Excessive Inflammatory Responses after GCRV Infection, BIOMOLECULES, 2020, 通讯作者
（9） Characterisation and function of TRIM23 in grass carp (Ctenopharyngodon idella), FISH & SHELLFISH IMMUNOLOGY, 2019, 第 2 作者
（10） Identification, characterisation and preliminary functional analysis of IRAK-M in grass carp (Ctenopharyngodon idella), FISH & SHELLFISH IMMUNOLOGY, 2019, 第 2 作者
（11） Identification, expression and functional characterisation of CYP1A in grass carp (Ctenopharyngodon idella), FISH & SHELLFISH IMMUNOLOGY, 2019, 第 2 作者
（12） Grass carp ATG5 and ATG12 promote autophagy but down-regulate the transcriptional expression levels of IFN-I signaling pathway, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 2 作者
（13） Different responses in one-year-old and three-year-old grass carp reveal the mechanism of age restriction of GCRV infection, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 4 作者
（14） Global and Complement Gene-Specific DNA Methylation in Grass Carp after Grass Carp Reovirus (GCRV) Infection, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 通讯作者
（15） Molecular cloning, expression analysis and localization pattern of the MST family in grass carp (Ctenopharyngodon idella), FISH & SHELLFISH IMMUNOLOGY, 2018, 第 2 作者
（16） Transcriptomics Sequencing Provides Insights into Understanding the Mechanism of Grass Carp Reovirus Infection, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 第 2 作者
（17） Molecular cloning and functional characterisation of NLRX1 in grass carp (Ctenopharyngodon idella), FISH & SHELLFISH IMMUNOLOGY, 2018, 第 2 作者
（18） Changes in gene and genotype frequencies during the development of the grass carp Ctenopharyngodon idella, JOURNAL OF FISH BIOLOGY, 2018, 
（19） Prediction of GCRV virus-host protein interactome based on structural motif-domain interactions, BMC BIOINFORMATICS, 2017, 第 2 作者
（20） Deep Circular RNA Sequencing Provides Insights into the Mechanism Underlying Grass Carp Reovirus Infection, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 第 1 作者
（21） Differences in responses of grass carp to different types of grass carp reovirus (GCRV) and the mechanism of hemorrhage revealed by transcriptome sequencing, BMC GENOMICS, 2017, 第 1 作者
（22） Bid-deficient fish delay grass carp reovirus (GCRV) replication and attenuate GCRV-triggered apoptosis, ONCOTARGET, 2017, 第 1 作者
（23） Deep Illumina sequencing reveals conserved and novel microRNAs in grass carp in response to grass carp reovirus infection, BMC GENOMICS, 2017, 第 1 作者
（24） 一种新型草鱼呼肠孤病毒人工感染方法, PRELIMINARY STUDY ON A NEW METHOD OF GCRV ARTIFICIAL INFECTION, 水生生物学报, 2016, 第 2 作者
（25） Cloning and characterization of Bax1 and Bax2 genes of Ctenopharyngodon idellus and evaluation of transcript expression in response to grass carp reovirus infection, FISH PHYSIOLOGY AND BIOCHEMISTRY, 2016, 第 2 作者
（26） 我国转基因鱼研制的历史回顾与展望, 生物工程学报, 2016, 第 2 作者
（27） The draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation, NATURE GENETICS, 2015, 第 36 作者
（28） Isolation and expression of grass carp toll-like receptor 5a (CiTLR5a) and 5b (CiTLR5b) gene involved in the response to flagellin stimulation and grass carp reovirus infection, FISH & SHELLFISH IMMUNOLOGY, 2015, 第 2 作者
（29） Global gene expression patterns of grass carp following compensatory growth, BMC GENOMICS, 2015, 第 1 作者
（30） Rana grylio virus (RGV) envelope protein 2L: subcellular localization and essential roles in virus infectivity revealed by conditional lethal mutant, JOURNAL OF GENERAL VIROLOGY, 2014, 第 1 作者
（31） A conditional lethal mutation in Rana grylio virus ORF 53R resulted in a marked reduction in virion formation, VIRUS RESEARCH, 2013, 第 1 作者
（32） Nonstructural Protein NS80 Is Crucial in Recruiting Viral Components to Form Aquareoviral Factories, PLOS ONE, 2013, 第 2 作者
（33） Rana grylio virus as a vector for foreign gene expression in fish cells, VIRUS RESEARCH, 2012, 第 1 作者
（34） Turbot reovirus (SMReV) genome encoding a FAST protein with a non-AUG start site, BMC GENOMICS, 2011, 第 2 作者
（35） 蛙虹彩病毒一个序列保守基因（RGV-12L）的克隆表达及定位分析, CLONING, EXPRESSION AND LOCALIZATION ANALYSIS OF A SEQUENCE CONSERVED GENE (RGV-12L) FROM RANA GRYLIO VIRUS, 水生生物学报, 2010, 第 1 作者

   

（ 1 ） 草鱼出血病抗性基因的全基因组发掘, 负责人, 国家任务, 2018-01--2020-12
（ 2 ） 草鱼出血病抗性基因的发掘, 负责人, 地方任务, 2018-01--2019-12
（ 3 ） 转基因黄河鲤的基因组选育, 参与, 国家任务, 2017-01--2020-12
（ 4 ） 草鱼发育早期基因型频率变化的研究, 负责人, 研究所自主部署, 2017-01--2017-12
（ 5 ） 草鱼对不同类型GCRV的免疫应答机制研究, 负责人, 研究所自主部署, 2016-01--2017-12
（ 6 ） 自噬拮抗GCRV的分子机制及育种潜力, 负责人, 国家任务, 2021-01--2024-01
（ 7 ） 中国科学院青年创新促进会项目, 负责人, 中国科学院计划, 2021-01--2024-01