Professor of Biophysics
Soft Matter Phys Lab
Institute of Physics
Chinese Academy of Sciences
Email:weichi@aphy.iphy.ac.cn
Telephone:010-82649497
Address:No. 8, 3rd south street, Zhong Guan Cun, Beijing
Postcode:100190
Research Areas
(1) Biological clocks, neural network and neurodynamics
(2) Theoretical study of the protein-protein, protein-DNA and Protein-RNA interactions
(3) Nonlinear dynamics of calcium signaling
Education
Nanjing University 1980-1984 B.Sc.
Institute of Biophysics, CAS 1990--1993 Ph.D.
Experience
Work Experience
1997.11-2000.1, UCSF, Postdoc
Publications
Papers
1. Cong-xin Li, Xiao-fang Chen, Peng-ye Wang, Wei-chi Wang (2009) Circadian KaiC Phosphorylation: A Multi-Layer Network PLoS Comput Biol 5(11): e1000568.
2. Xiao-fang Chen, Cong-xin Li, Peng-ye Wang, Ming Li, Wei-chi Wang (2008)Dynamic simulation of the effect of calcium-release activated calcium channel on cytoplasmic Calcium oscillation Biophysical Chemistry vol.136, 87-95.
3. Cong-xin Li, Xiao-fang Chen, Peng-ye Wang, Wei-chi Wang (2010) Effects of CRAC Channel on Spatiotemporal Ca2+ Patterns in T CellsCHIN PHYS. LETT. Vol. 27, 028701.
4. Xiao-fang Chen, Cong-xin Li, Peng-ye Wang, Wei-chi Wang (2010) Cytoplasmic Ca2+ Dynamics under the Interplay between the Different IP3R Gating Models and the Plasma Membrane Ca2+ Influx CHIN PHYS. LETT. Vol. 27, 010504.
5. Hong-Yan Zhang, Yu-Ru Liu, Wei Li, Hui Li, Shuo-Xing Dou, Ping Xie, Wei-Chi Wang, Peng-Ye Wang (2014) Condensations of single DNA molecules induced by heptaplatin and its chiral isomer AIP Advances vol.4(8):1203-1209.
6. Hong-Yan Zhang, Chao Ji, Yu-Ru Liu, Wei Li, Hui Li, Shuo-Xing Dou, Wei-Chi Wang, Ling-Yun Zhang, Ping Xie, Peng-Ye Wang (2014) Effects of pH on Oxaliplatin-Induced Condensation of Single DNA Molecules CHIN. PHYS. LETT. Vol. 31, No. 2 , 028701.
7. Hong-Yan Zhang, Yu-Ru Liu, Chao Ji, Wei Li, Shuo-Xing Dou, Ping Xie, Wei-Chi Wang, Ling-Yun Zhang, Wang, Peng-Ye (2013) Oxaliplatin and Its Enantiomer Induce Different Condensation Dynamics of Single DNA Molecules Plos One, 8(8):e71556.
8. Yu-Ru Liu, Chao Ji, Hong-Yan Zhang, Shuo-Xing Dou, Ping Xie, Wei-Chi Wang, Peng-Ye Wang (2013) Transplatin enhances effect of cisplatin on both single DNA molecules and live tumor cells Archives of Biochem & Biophysics, vol 536(1):12-24.
9. Hui Li, Zhao-Wen Duan, Ping Xie, Yu-Ru Liu, Wei-Chi Wang, Shuo-Xing Dou, Pengy-Ye Wang (2012) Effects of Paclitaxel on EGFR Endocytic Trafficking Revealed Using Quantum Dot Tracking in Single Cells Plos One, vol 7(9):e45465.
10. Wei Li, Zhi-Qiang Sun, Ping Xie, Shuo-Xing Dou, Wei-Chi Wang, Peng-Ye wang (2012) Elastic response and length change of single DNA molecules induced by a combination of cisplatin and transplatin Phys Rev E, vol. 85(2 Pt 1):021918.
11. Hui Li, Shuo-Xing Dou, Yu-Ru Liu, Wei Li, Ping Xie, Wei-Chi Wang, Peng-Ye Wang (2-15) Mapping Intracellular Diffusion Distribution Using Single Quantum Dot Tracking: Compartmentalized Diffusion Defined by Endoplasmic Reticulum J. Am. Chem Sco., vol. 137 (1), 436–444.
Students
已指导学生
陈晓芳 博士研究生 070205-凝聚态物理
李丛鑫 博士研究生 070205-凝聚态物理
魏孔吉 博士研究生 070205-凝聚态物理