General

Zhuo Wang, Ph.D, Associate Professor                                                         

Glyco-Bioengineering Group, State Key Laboratory of Biochemical Engineering

Institute of Process Engineering, Chinese Academy of Sciences

1 North 2nd Street,

Zhongguancun, Haidian District,

Beijing, PR China, 100190

wangzhuo@ipe.ac.cn


Research Areas

Host-pathegen interation and relationship


Biosynthesis of fungal cell wall/biofilm polysaccharides


Development of natural antimicrobial drugs


Development of microfluidic chip based platforms for biological studies


Education

2010-2014      Postdoctoral Fellow, Department of Molecular Microbiology,

                       Washington University in St. louis Medical School

                       Mentor: Tamara Doering

                       Study on Xylose-phosphate transferase in yeast

 

2004-2010      PhD study in Biochemistry & Molecular Biology,

                      University of Oklahoma Health Sciences Center

                      Mentor: Dr. Christopher M. West

                      Study on cytoplasmic sugar transferase in Eukaryotic cells  

 

1997-2001      B.S in Biochemistry, Sichuan University

                      Graduated with a bachelor degree in biochemistry


Experience



Work Experience

2017-now   Associate Professor,

Institute of Process Engineering, Chinese Academy of Sciences

 

2014-2017  Assistant Professor,

Institute of Process Engineering, Chinese Academy of Sciences


Publications

   
Papers

Jing, B., Wang, Z.A., Zhang C., Deng, Q., Wei, J., Luo, Y., Zhang, X., Li, J., DU, Y. Establishment and Application of Peristaltic Human Gut-Vessel Microsystem for Studying Host-Microbial Interaction, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, MAR 31

 

Jing, B., Cheng, G., Li, J., Wang, Z.A.*, DU, Y. Inhibition of Liver Tumor Cell Metastasis by Partially Acetylated Chitosan Oligosaccharide on A Tumor-Vessel Microsystem. Mar. Drugs 2019,17, 415

 

Li, R., Yuan, X., Wei, J., Zhang, X., Cheng, G., Wang, Z.A.*, DU, Y. Synthesis and evaluation of a Chitosan oligosaccharide-streptomycin conjugate against Pseudomonas aeruginosa biofilms. Mar. Drugs 2019, 17(1), 43

 

Zhang C., Jiao, S., Wang, Z.A.*, Du, Y. Exploring Effects of Chitosan Oligosaccharides on Mice Gut Microbiota in in vitro Fermentation and Animal Model. Frontiers in Microbiology. 2018 Oct 09

 

Wei, J., Wang, Z.A., Wang, B., Jahan, M., Wang, Z., Wynn, P. C., and Du, Y. (2018) Characterization of porcine milk oligosaccharides over lactation between primiparous and multiparous female pigs. Scientific Reports.8:4688.

 

Mao, R., Qi, L., Wang, Z.*, Liu, H., and Du, Y. (2018) Helix loop-mediated isothermal amplification of nucleic acids. Rsc Adv 8, 19098-19102

 

Zhang, G., Liu, J., Li, R., Jiao, S., Feng, C., Wang, Z. A.*, and Du, Y. (2018) Conjugation of Inulin Improves Anti-Biofilm Activity of Chitosan. Mar Drugs 16

 

Qi, L., Mao, R., Wu, P., Wang, Z., Ye, Y., and Du, Y. (2018) A Rapid Competitive Annealing Mediated Isothermal Amplification Microfluidic Chip for Cyprinid herpesvirus Detection. Journal of Shenyang Agricultural University 49, 220-226

 

Wang, Z. A., Li, L. X., and Doering, T. L. (2018) Unraveling synthesis of the cryptococcal cell wall and capsule. Glycobiology 28, 719-730

 

Mao, R., Qi, L., Li, J., Sun, M., Wang, Z.*, and Du, Y. (2018) Competitive annealing mediated isothermal amplification of nucleic acids. Analyst 143, 639-642

 

Mao, R., Ge, G., Wang, Z., Hao, R., Zhang, G., Yang, Z., Lin, B., Ma, Y., Liu, H., and Du, Y. (2018) A multiplex microfluidic loop-mediated isothermal amplification array for detection of malaria-related parasites and vectors. Acta Trop 178, 86-92

 

Li, R., Wang, Z*., and Du, Y. (2017) Recent progress in Candida albicans biofilm. Acta Microbiologica Sinica 57, 1206-1218

 

Meng, X. P., Jiao, S. M., Qin, S. Q., Yang, X. B., Li, J. S., Wei, J. H., Wang, Z., and Du, Y. G. (2017) Comparative Study on Milk Oligosaccharides in Buffalo and Cow Colostrum Milk. Prog Biochem Biophys 44, 942-948

 

Kyung J. Kwon-Chung, James A. Fraser, Tamara L. Doering, Zhuo Wang, Guilhem Janbon, Alexander Idnurm, and Yong-Sun Bahn. Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis. In Cold Spring Harbor Monograph on Human Fungal Pathogens, edited by Arturo Casadevall, Aaron P. Mitchell, J. Berman, K.J. Kwon-Chung, J.R. Perfect, and J. Heitman. Invited review, 2014


Research Interests