声操控，超声微流控，复杂介质中的声传播

• 【拟研究课题】：
• 超声操控微纳米颗粒理论研究；
• 基于人工声场的超声操控微纳颗粒的原理、现象、机制研究；
• 基于MEMS工艺的超声微流控关键技术研究；
• 超声与细胞、生物组织的生物效应研究。
• 【背景要求】
• 物理、力学、声学、生物医学工程等专业​；
• 具有一定的数理基础，英语通过CET6。

070206-声学
083100-生物医学工程

生物医学超声
声镊，声操控
声子晶体应用

2003-09--2008-07   武汉大学   博士
1999-09--2003-07   华中师范大学   学士

   

   

   

2008-07~现在, 中科院深圳先进技术研究院, 助理研究员/副研究员/研究员

   

   

   

（1）  2016年广东省科学技术发明奖一等奖, 一等奖, 省级, 2016

（ 1 ） 基于结构声场操控和筛选颗粒的系统及方法, 发明, 2013, 第 2 作者, 专利号: 201310080968.5
（ 2 ） 一种基于声场操控的纳米粒子靶向递送方法, 发明, 2015, 第 5 作者, 专利号: CN201510925588.6
（ 3 ） 基于人工结构声场的微流体系统及操控微粒的方法, 发明, 2015, 第 1 作者, 专利号: 201510655483.3

1. Wei Zhou*, Jingjing Wang*, Kaiyue Wang*, Bin Huang, Lili Niu, Fei Li, Feiyan Cai, Yan Chen, Xin Liu, Xiaoyan Zhang, Hankui Cheng, Lijun Kang#, Long Meng#, Hairong ,Zheng#, Ultrasound neuro-modulation chip: activation of sensory neurons in Caenorhabditis elegans by surface acoustic waves. Lab on a Chip. 10.1039/c7lc00163k. (2017). （封面文章）

2. 黄先玉, 蔡飞燕^#，李文成, 郑海荣, 何兆剑, 邓科^#, 赵鹤平. 空气中一维声栅对微粒的声操控. 物理学报 66, 44301-044301 (2017).

3. Mian Chen, Feiyan Cai, Chen Wang, Zhiyong Wang, Long Meng, Fei Li, Pengfei Zhang, Xin Liu, Hairong Zheng^#. Observation of Metal Nanoparticles for Acoustic Manipulation. Advanced Science, 1600447 (2017).

4. Chen Wang, Feiyan Cai^#, Fei Li, Long Meng, Jiangyu Li, Junru Wu, Yan Kang^#, Hairong Zheng. A highly sensitive compact liquid sensor based on slotted phononic crystal plates. Lab on a Chip (2016).

5. Wei Zhou, Lili Niu, Feiyan Cai, Fei Li, Chen Wang, Xiaowei Huang, Jingjing Wang, Junru Wu, Long Meng, Hairong Zheng. Spatial selective manipulation of microbubbles by tunable surface acoustic waves. Biomicrofluidics 10 (2016).

6. Chaowei Xu^*, Feiyan Cai^*, Shuhong Xie, Fei Li, Rong Sun, Xianzhu Fu, Rengen Xiong, Yi Zhang, Hairong Zheng, Jiangyu Li. Phononic Crystal Tunable via Ferroelectric Phase Transition. Physical Review Applied 4 (2015).

7. Feiyan Cai, Fei Li, Long Meng, Junru Wu, Hairong Zheng. Strong localization of an acoustic wave in a sub-wavelength slot between two plates. The Journal of the Acoustical Society of America 137, 1251-1256 (2015).

8. K. Jagajjanani Rao, Fei Li, Long Meng, Hairong Zheng, Feiyan Cai^#, Wei Wang^#. A Force to Be Reckoned With: A Review of Synthetic Microswimmers Powered by Ultrasound. Small 11, 2836-2846 (2015).

9. Long Meng, Zhiting Deng, Lili Niu, Fei Li, Fei Yan, Junru Wu, Feiyan Cai^#, Hairong Zheng^#. A Disposable Microfluidic Device for Controlled Drug Release from Thermal-Sensitive Liposomes by High Intensity Focused Ultrasound. Theranostics 5, 1203-1213 (2015).

10. 郑海荣, 蔡飞燕， 严飞, 牛丽丽, 李飞, 孟龙, 邱维宝. 多功能生物医学超声: 分子影像、给药与神经调控. 科学通报 60, 1864-1873 (2015).

11. Fei Li, Feiyan Cai*, Zhengyou Liu, Long Meng, Ming Qian, Chen Wang, Qian Cheng, Menglu Qian, Xin Liu, Junru Wu, Jiangyu Li, and Hairong Zheng, "Phononic-Crystal-Based Acoustic Sieve for Tunable Manipulations of Particles by a Highly Localized Radiation Force," Physical Review Applied, 1, 051001, (2014). （Research Highlights）

12. Jie Zhang, Long Meng, Feiyan Cai, Hairong Zheng, and Charles R. P. Courtney, "Multi-scale patterning of microparticles using a combination of surface acoustic waves and ultrasonic bulk waves," Applied Physics Letters, 104, 224103 (2014).

13. Long Meng, Feiyan Cai^#, Peng Jiang, Zhiting Deng, Fei Li, Lili Niu, Yan Chen, Junru Wu, and Hairong Zheng#, “On-chip targeted single cell sonoporation with microbubble destruction excited by surface acoustic waves.” Applied Physics Letters 104 (7), 073701 (2014).

14. Long Meng*, Feiyan Cai*, Juanjuan Chen, Lili Niu, Yanming Li, Junru Wu, and Hairong Zheng#, "Precise and programmable manipulation of microbubbles by two-dimensional standing surface acoustic waves," Applied Physics Letters, 100, 173701 (2012).

15. Feiyan Cai, Zhaojian He, Zhengyou Liu, Long Meng, Xin Cheng, and, Hairong Zheng, “Acoustic trapping of particle by a periodically structured stiff plate.” Applied Physics Letters. 99, 253505 (2011).

16. Long Meng, Feiyan Cai*, Zidong Zhang, Lili Niu, Qiaofeng Jin, Fei Yan, Junru Wu, Zhanhui Wang and Hairong Zheng "Transportation of single cell and microbubbles by phase-shift introduced to standing leaky surface acoustic waves," Biomicrofluidics 5 (4), 044104 (2011).（Research Highlights）

17. Long Meng, Feiyan Cai, Qiaofeng Jin, Lili Niu, Chunxiang Jiang, Zhanhui Wang, Junru Wu, and Hairong Zheng, " Acoustic aligning and trapping of microbubbles in an enclosed PDMS microfluidic device"  Sensors and Actuators B: Chemical, 160, 1599-1605 (2011).

18. Jiang Chunxiang, Li Xiang, Yan Fei, Wang Zhanhui, Jin Qiaofeng, Cai Feiyan, Qian Ming, Liu Xin, Zhang Lijuan, Zheng Hairong. Microfluidic-assisted formation of multifunctional monodisperse microbubbles for diagnostics and therapeutics. Micro & Nano Letters, IET 6, 417-421 (2011).

19. Feiyan Cai, Long Meng, Chunxiang Jiang, Yu Pan, and Hairong Zheng, “Computation of the acoustic radiation force using the finite-difference time-domain method” The Journal of the Acoustical Society of America, 128,4 (2010).

20. Feiyan Cai, Zhaojian He, Anqi Zhang, Yiqun Ding, Zhengyou Liu, “Anomalous Doppler effects in bulk phononic crystal”. Physics Letters A, 374, 3971-3976 (2010).

21. Feiyan Cai, Zhaojian He, Degang Zhao, and Zhengyou Liu, “Scholte surface wave in a soft film deposited on rigid plate immersed in water: Dispersion relation and collimation effect”, Journal Of Applied Physics. 107, 064505 (2010).

22. Zhaojian He, Han Jia, Chunyin Qiu, Shasha Peng, Xuefei Mei, Feiyan Cai, Pai Peng, Manzhu Ke, and Zhengyou Liu, “Acoustic Transmission enhancement through a periodically structured stiff plate without any opening” Physical Review Letters. 105, 074301 (2010).

23. Fengming Liu, Feiyan Cai., Shasha Peng, Rui Hao, Manzhu Ke, and Zhengyou Liu, “Parallel acoustic near-field microscope: A steel slab with a periodic array of slits”. Physical Review E, 80 2 (2009).

24. Zhaojian He, Feiyan Cai, Yiqun Ding, and Zhengyou Liu, “Subwavelength imaging of acoustic waves by a canalization mechanism in a two-dimensional phononic crystal”, Applied Physics Letters. 93, 233503 (2008).

25. Zhaojian He, Feiyan Cai, and Zhengyou Liu, “Guiding acoustic waves with graded phononic crystals”, Solid State Communications 148, 74-77 (2008).

26. Fengming Liu, Feiyan Cai, Yiqun Ding, and Zhengyou Liu, “Tunable transmission spectra of acoustic waves through double phononic crystal slabs”, Applied Physics Letters. 92, 103504 (2008).

27. Feiyan Cai, Fengming Liu, Zhaojian He, and Zhengyou Liu, “High refractive-index sonic material based on periodic subwavelength structure”, Applied Physics Letters. 91, 203515 (2007).

28. Degang Zhao, Zhengyou Liu, Chunyin Qiu, Zhaojian He, Feiyan Cai, Manzhu Ke. Surface acoustic waves in two-dimensional phononic crystals: Dispersion relation and the eigenfield distribution of surface modes. Physical Review B 76, 144301 (2007).

29. Zhaojian He, Shasha Peng, Feiyan Cai, Manzhu Ke, Zhengyou Liu. Acoustic Bloch oscillations in a two-dimensional phononic crystal. Physical Review E 76, 056605 (2007)

   

   

（ 1 ） 超声操控血管中微纳米药物颗粒定点聚集的动力学行为研究, 主持, 国家级, 2010-01--2012-12
（ 2 ） 基于声子晶体板调控声场的微纳颗粒操控研究, 主持, 国家级, 2013-01--2016-12
（ 3 ） 基于高品质因子狭缝局域声场的流体传感器检测机理与关键技术研究, 主持, 省级, 2015-09--2017-09
（ 4 ） 基于狭缝超强局域模式的片上超声微流控系统特性及其应用研究, 主持, 国家级, 2017-01--2020-12

   

   

   

已指导学生

郭宁  02  19250