Marine ecological toxicology

   

（1） Impact of metal pollution on shrimp Crangon affinis by NMR-based metabolomics, Mar. Pollut. Bullet., 2016, Corres​ponding author.
（2） A metabolomic study on the biological effects of metal pollutions in oysters Crassostrea sikamea, Mar. Pollut. Bullet., 2016, Corres​ponding author.
（3） roteomic and metabolomic analysis on the toxicological effects of As (III) and As (V) in juvenile mussel Mytilus galloprovincialis, Chemosphere, 2016, Corres​ponding author.
（4） An integrated proteomic and metabolomic study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA), Chemosphere, 2016, Corres​ponding author.
（5） Both released silver ions and particulate Ag contribute to the toxicity of AgNPs to earthworm Eisenia fetida, Nanotoxicology, 2015, Corres​ponding author.
（6） Comparative investigations on the biological effects of As (III) and As (V) in clam Ruditapes philippinarum using multiple biomarkers, Fish & Shellfish Immunol., 2015, Corres​ponding author.
（7） 典型持久性有机污染物与抑癌基因相互作用的分子模拟与验证., 科学通报, 2015, 第 1 作者
（8） BDE-47对人胚肾细胞HEK293的毒理效应及作用机制, 生态毒理学报, 2015, 第 3 作者
（9） 不同形态磷源对具槽帕拉藻(Paralia sulcata)生长和磷酸酶活性的影响, 海洋与湖沼, 2015, 第 4 作者
（10） A metabolomic study on the responses of daphnia magna exposed to silver nitrate and coated silver nanoparticles, Ecotoxicol. Environ. Saf., 2015, Corres​ponding author.
（11） Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms, Chin. J. Oceanol. Limnol., 2015, Corres​ponding author.
（12） Multiple biomarkers of biological effects induced by cadmium in clam Ruditapes philippinarum, Fish & Shellfish Immunol., 2015, Corres​ponding author.
（13） A defensin from clam Venerupis philippinarum: Molecular characterization, localization, antibacterial activity, and mechanism of action, Dev. Comp. Immunol., 2015, Corres​ponding author.
（14） Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells, Chemosphere, 2015, First author.
（15） Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO2, Comp. Biochem. Physiol. Part D, 2015, Corres​ponding author.
（16） Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO2, Comp. Biochem. Physiol. Part D, 2015, Corres​ponding author.
（17） A metabolomic investigation of the effects of metal pollution in oysters Crassostrea hongkongensis, Mar. Pollut. Bullet., 2015, Corres​ponding author.
（18） Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study, Toxicol. Lett., 2015, Corres​ponding author.
（19） Proteomic and metabolomic responses of Pacific oyster Crassostrea gigas to elevated pCO2 exposure, J. Proteomics, 2015, Corres​ponding author.
（20） Determination and prediction of the binding interaction between organophosphate flame retardants and p53, Chem. Res. Toxicol., 2014, Corres​ponding author.
（21） iTRAQ-based quantitative proteomic analyses on the gender-specific responses in mussel Mytilus galloprovincialis to tetrabromobisphenol A, Aquat. Toxicol, 2014, Corres​ponding author.
（22） The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach, Mar. Pollut. Bull., 2014, Corres​ponding author.
（23） Molecular responses of European flounder (Platichthys flesus) chronically exposed to contaminated estuarine sediments, Chemosphere, 2014, Third author.
（24） Molecular characterization of two glutathione peroxidase genes in Mytilus galloprovincialis and their transcriptional responses to sub-chronic arsenate and cadmium exposure, Invertebrate Surviv. J., 2014, Corres​ponding author.
（25） Identification and mRNA expression of two 17β-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis following exposure to endocrine disrupting chemicals., Environ. Toxicol. Pharmacol., 2014, Corres​ponding author.
（26） Gender-specific metabolic responses in gonad of mussel Mytilus galloprovincialis to 2,2′,4,4′-tetrabromodiphenyl ether, Environ. Toxicol. Pharmacol., 2014, Corres​ponding author.
（27） Metabolomic analysis revealed that female mussel Mytilus galloprovincialis was sensitive to bisphenol A exposures., Environ. Toxicol. Pharmacol., 2014, Corres​ponding author.
（28） Expression profiles of two small heat shock proteins and antioxidant enzyme activity in Mytilus galloprovincialis exposed to cadmium at environmentally relevant concentrations., Chin. J. Oceanol. Limnol., 2014, Corres​ponding author.
（29） Soil acidification increases metal extractability and bioavailability in old orchard soils of Northeast Jiaodong Peninsula in China., Environ. Pollut., 2014, Corres​ponding author.
（30） Evaluation of protein extraction protocols for 2DE in marine ecotoxicoproteomics., Proteomics, 2014, Corres​ponding author.
（31） Proteomic and metabolomic responses in hepatopancreas of Mytilus galloprovincialis challenged by Micrococcus luteus and Vibrio anguillarum., J. Proteomics, 2013,  First author.
（32） Effect of cadmium on the defense response of Pacific oyster Crassostrea gigas to Listonella anguillarum challenge., Chin. J. Oceanol. Limnol., 2013, Corres​ponding author.
（33） Proteomic and metabolomic analysis of earthworm Eisenia fetida exposed to different concentrations of 2,2’,4,4’-tetrabromodiphenyl ether., J. Proteomics, 2013, Corres​ponding author.
（34） Proteomic and metabolomic analysis reveal gender-specific responses of mussel Mytilus galloprovincialis to 2,2’,4,4’-tetrabromodiphenyl ether (BDE 47)., Aquat. Toxicol., 2013, Corres​ponding author.
（35） Responses of Mytilus galloprovincialis to bacterial challenges by metabolomics and proteomics., Fish Shellfish Immunol., 2013, Corres​ponding author.
（36） The response profiles of HSPA12A and TCTP from Mytilus galloprovincialis to pathogen and cadmium challenge., Fish Shellfish Immunol., 2013, Corres​ponding author.
（37） A novel C-type lysozyme from Mytilus galloprovincialis: Insight into innate immunity and molecular evolution of invertebrate C-type lysozymes., PLOS One, 2013, Corres​ponding author.
（38） Regulation of metabolites, gene expression, and antioxidant enzymes to environmentally relevant lead and zinc in the halophyte Suaeda salsa., J. Plant Growth Regul., 2013,  First author.
（39） Molecular cloning, characterization and expression profiles of thioredoxin 1 and thioredoxin 2 genes in Mytilus galloprovincialis., Chin. J. Oceanol. Limnol., 2013, Corres​ponding author.
（40） An integrated proteomic and metabolomic study on the chronic effects of mercury in Suaeda salsa under an environmentally relevant salinity., PLOS One, 2013, Corres​ponding author.
（41） Proteomic and metabolomic responses of clam Ruditapes philippinarum to arsenic exposure under different salinities., Aquat. Toxicol., 2013,  First author.
（42） Proteomic and metabolomic responses of clam Ruditapes philippinarum to arsenic exposure under different salinities., Aquat. Toxicol., 2013,  First author.
（43） Molecular characterization of a manganese superoxide dismutase and copper/zinc superoxide dismutase from the mussel Mytilus galloprovincialis, Fish Shellfish Immunol., 2013, Corres​ponding author.
（44） Molecular characterization of a manganese superoxide dismutase and copper/zinc superoxide dismutase from the mussel Mytilus galloprovincialis, Fish Shellfish Immunol., 2013, Corres​ponding author.
（45） Molecular characterization of a manganese superoxide dismutase and copper/zinc superoxide dismutase from the mussel Mytilus galloprovincialis, Fish Shellfish Immunol., 2013, Corres​ponding author.
（46） The influence of salinity on toxicological effects of arsenic in digestive gland of clam Ruditapes philippinarum using metabolomics., Chin. J. Oceanol. Limnol, 2013, Corres​ponding author.
（47） A metabolomics investigation on arsenic-induced toxicological effects in the clam Ruditapes philippinarum under different salinities., Ecotoxicol. Environ. Saf., 2013,  First author.
（48） Manila clam Venerupis philippinarum as a biomonitor to metal pollution., Chin. J. Oceanol. Limnol., 2013,  First author.
（49） Effects of heavy metals on the expression of a zinc-inducible metallothionein-III gene and antioxidant enzyme activities in Crassostrea gigas., Ecotoxicology, 2012, Corres​ponding author.
（50） Two goose-type lysozymes in Mytilus galloprovincialis: possible function diversification and adaptive evolution., PLoS one, 2012, Corres​ponding author.
（51） Toxicological responses in halophyte Suaeda salsa to mercury under environmentally relevant salinity., Ecotoxicol. Environ. Saf., 2012,  First author.
（52） Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics., Ecotoxicology, 2012,  First author.
（53） Effects of salinity on metabolic profiles, gene expressions, and antioxidant enzymes in halophyte Suaeda salsa., J. Plant Growth Regul., 2012,  First author.
（54） Salinity-induced effects in the halophyte Suaeda salsa using NMR-based metabolomics, Plant Mol. Biol. Rep., 2012,  First author.
（55） Identification and expression profile of a new cytochrome P450 isoform (CYP414A1) in the hepatopancreas of Venerupis philippinarum exposed to benzo[a]pyrene, cadmium and copper., Environ. Toxicol. Pharmacol., 2012, Corres​ponding author.
（56） Molecular cloning and differential expression patterns of sigma and omega glutathione S-transferases from Venerupis philippinarum to heavy metals and benzo[a]pyrene exposure., Chin. J. Oceanol. Limnol.,, 2012, Corres​ponding author.
（57） Docking and QSAR study on the binding interactions between polycyclic aromatic hydrocarbons and estrogen receptor., Ecotoxicol. Environ. Saf., 2012, Corres​ponding author.
（58） Expression profiles of seven glutathione S-transferase (GST) genes from Venerupis philippinarum exposed to heavy metals and benzo[a]pyrene. Comp., Biochem. Physiol. Part C, 2012, Corres​ponding author.
（59） Uptake pathways and subcellular fractionation of Cd in the polychaete Nereis diversicolor., Ecotoxicology, 2012, Corres​ponding author.
（60） Pathways of cadmium fluxes in the root of the halophyte Suaeda salsa., Ecotoxicol. Environ. Saf., 2012, Corres​ponding author.
（61） Differential toxicological effects induced by mercury in gills from three pedigrees of Manila clam Ruditapes philippinarum by NMR-based metabolomics, Ecotoxicology, 2011, Corres​ponding author.
（62） Toxicological responses to acute mercury exposure for three species of Manila clam Ruditapes philippinarum by NMR-based metabolomics, Environ. Toxicol. Pharmacol., 2011, Corres​ponding author.
（63） Tissue-specific toxicological effects of cadmium in green mussel (Perna viridis): Nuclear magnetic resonance-based metabolomics study, Environ. Toxicol. Chem., 2011,  First author.
（64） Benzo(a)pyrene-induced metabolic responses in Manila clam Ruditapes philippinarum by proton nuclear magnetic resonance (1H NMR) based metabolomics, Environ. Toxicol. Pharmacol., 2011, Corres​ponding author.
（65） Metabolic responses in gills of Manila clam Ruditapes philippinarum exposed to copper using NMR-based metabolomics, Mar. Environ. Res., 2011, Corres​ponding author.
（66） Metabolomic study on the halophyte Suaeda salsa in the Yellow River Delta, Clean Soil, Air, Water, 2011, Corres​ponding author.
（67） Metabolic profiling of cadmium-induced effects in one pioneer intertidal halophyte Suaeda salsa by NMR-based metabolomics, Ecotoxicology, 2011, Corres​ponding author.
（68） Responses of thioredoxin 1 and thioredoxin-related protein 14 mRNAs to cadmium and copper stresses in Venerupis philippinarum, Comp. Biochem. Physiol. Part C, 2011, Corres​ponding author.
（69） QSAR studies on the depuration rates of polycyclic aromatic hydrocarbons, polybrominated diphenyl ethers and polychlorinated biphenyls in mussels (Elliptio complanata), Sar QSAR Environ. Res., 2011, Corres​ponding author.
（70） Assessment of three pedigrees of clam Ruditapes philippinarum as bioindicator for heavy metal monitoring using NMR-based metabolomics, Clean Soil, Air, Water, 2011, Corres​ponding author.
（71） NMR-Based metabolomic investigations on the differential responses in adductor muscles from two pedigrees of Manila clam Ruditapes philippinarum to cadmium and zinc., Mar. Drugs, 2011,  First author.
（72） Towards a system level understanding of non-model organisms sampled from the environment: A network biology approach., PLoS Comput. Biol., 2011, Fourth author.
（73） Towards a system level understanding of non-model organisms sampled from the environment: A network biology approach., PLoS Comput. Biol., 2011, Fourth author.
（74） Metabolic profiling of cadmium-induced effects in one pioneer intertidal halophyte Suaeda salsa by NMR-based metabolomics., Ecotoxicology, 2011, Corres​ponding author.
（75） Responses of thioredoxin 1 and thioredoxin-related protein 14 mRNAs to cadmium and copper stresses in Venerupis philippinarum., Comp. Biochem. Physiol. Part C, 2011, Corres​ponding author.
（76） Benzo(a)pyrene-induced metabolic responses in Manila clam Ruditapes philippinarum by proton nuclear magnetic resonance (1H NMR) based metabolomics., Environ. Toxicol. Pharmacol., 2011, Corres​ponding author.
（77） QSAR studies on the depuration rates of polycyclic aromatic hydrocarbons, polybrominated diphenyl ethers and polychlorinated biphenyls in mussels (Elliptio complanata)., SAR QSAR Environ. Res., 2011, Corres​ponding author.
（78） Metabolomic study on the halophyte Suaeda salsa in the Yellow River Delta., Clean-Soil, Air, Water, 2011, Corres​ponding author.
（79） Metabolomic study on the halophyte Suaeda salsa in the Yellow River Delta., Clean-Soil, Air, Water, 2011, Corres​ponding author.
（80） Metabolic responses in gills of Manila clam Ruditapes philippinarum exposed to copper using NMR-based metabolomics., Mar. Environ. Res., 2011, Corres​ponding author.
（81） Noncovalent interactions between hydroxylated polycyclic aromatic hydrocarbon and DNA: Molecular Docking and QSAR Study., Environ. Toxicol. Pharmacol., 2011, Corres​ponding author.
（82） Assessment of Clam Ruditapes philippinarum as heavy metal bioindicators using NMR-based metabolomics., Clean - Soil, Air, Water, 2011, Corres​ponding author.
（83） Docking and 3D-QSAR studies on the Ah receptor binding affinities of polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs)., Environ. Toxicol. Pharmacol., 2011, Corres​ponding author.
（84） Transcriptional regulation of selenium-dependent glutathione peroxidase from Venerupis philippinarum in response to pathogen and contaminants challenge, Fish Shellfish Immunol., 2011, Corres​ponding author.
（85） Toxicological effects induced by cadmium in gills of Manila clam Ruditapes philippinarum using NMR-based metabolomics., Clean-Soil, Air, Water, 2011, Corres​ponding author.
（86） Differential toxicological effects induced by mercury in gills from three pedigrees of Manila clam Ruditapes philippinarum by NMR-based metabolomics., Ecotoxicology, 2011, Corres​ponding author.
（87） Toxicological responses to acute mercury exposure for three species of Manila clam Ruditapes philippinarum by NMR-based metabolomics., Environ. Toxicol. Pharmacol., 2011, Corres​ponding author.
（88） Tissue-specific toxicological effects of cadmium in green mussel (Perna viridis): Nuclear magnetic resonance-based metabolomics study., Environ. Toxicol. Chem., 2011,  First author.
（89） Molecular phylogenies and evolutionary behavior of AhR (aryl hydrocarbon receptor) pathway genes in aquatic animals: Implications for the toxicology mechanism of some persistent organic pollutants (POPs), Chemosphere, 2010, Third author.
（90） Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model, Environ. Sci. Technol., 2010, Fourth author.
（91） NMR-based metabolomic studies on the toxicological effects of cadmium and copper on green mussels Perna viridis, Aquat. Toxicol., 2010,  First author.
（92） Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene, Environ. Sci. Technol., 2009, Second author.
（93） Metabolic profiling studies on the toxicological effects of Realgar in rats by 1H NMR spectroscopy, Toxicol. Appl. Pharmacol., 2009, Third author.
（94） Toxicological effects of Cinnabar in rats by NMR-based metabolic profiling of urine and serum, Toxicol. Appl. Pharmacol., 2008, Third author.
（95） High throughput tissue extraction protocol for NMR and Mass spectrometry based metabolomics, Anal. Biochem., 2008,  First author.
（96） Evaluation of metabolite extraction strategies from tissue samples using NMR metabolomics, Metabolomics, 2007,  First author.
（97） Investigation on the acute biochemical effects of Ce(NO3)3 on liver and kidney Tissues by MAS 1H NMR spectroscopic-based metabonomic approach, J. Rare Earths, 2006,  First author.
（98） Studies on acute toxicity of model toxins by proton magnetic resonance spectroscopy of urine combined with two-step cluster analysis,  Chin. J. Anal. Chem., 2006,  First author.
（99） Comparison of biochemical effects induced by Changle between male and female rats using NMR and ICP-MS techniques, J. Rare Earths, 2006,  First author.
（100） NMR-Based metabonomic study on the sub-acute biochemical effects of (Aristolochic acid), Food Chem. Toxicol., 2006, Second author.
（101） Studies of the acute toxicities of Lu(NO3)3 by NMR and pattern recognition techniques, Chem. J. Chin. Univ., 2005,  First author.
（102） Bioeffects of rare earth complex on rats studied by NMR and ICP-MS spectroscopy, J. Rare Earths, 2005,  First author.
（103） Studies on the acute biochemical effects of La(NO3)3 using 1H NMR spectroscopy of urine combined with pattern recognition, J. Inorg. Biochem., 2005,  First author.
（104） Acute biochemical effects of La(NO3)3 on liver and kidney tissues by MAS 1H NMR and pattern recognition, Anal. Biochem., 2005,  First author.
（105） Comparison of metabolic profiles from serum for the hepatotoxin-treated rats by NMR spectroscopic-based metabonomic analysis, Anal. Biochem., 2005,  First author.
（106） NMR spectroscopic-based metabonomic investigation on the acute biochemical effects induced by Ce(NO3)3 in rats, J. Inorg. Biochem., 2005,  First author.
（107） NMR and pattern recognition studies on the acute biochemical effects of Lu(NO3)3, Chin. J. Chem., 2004,  First author.
（108） 1H NMR spectroscopic studies on the acute toxicities of Lu(NO3)3 by biological fluids, Chin. J. Anal. Chem., 2004,  First author.

已指导学生

张林宝  01  19367  

张杏艳  02  49789  

刘小莉  01  19367  

章盈盈  02  63224  

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由丽萍  01  19367  

曹璐璐  02  67011  

魏磊  01  19367  

陈丽竹  02  19156  

现指导学生

刘佳琳  01  19367  

于德良  01  19367  

张明兴  02  19156  

钟鸣宇  01  19156  

徐兰兰  01  19156  

王爽  02  19156  

路珍  01  19156