基本信息
颜一军  男    中国科学院昆明植物研究所
电子邮件: yanyijun@mail.kib.ac.cn
通信地址: 云南省昆明市盘龙区蓝黑路132号
邮政编码:

教育背景

2007-09--2013-07   东北农业大学   博士
2003-09--2007-07   东北农业大学   学士

工作经历

   
工作简历
2022-02~现在, 中国科学院昆明植物研究所, 研究员
2017-01~2022-02,中国科学院昆明植物研究所, 副研究员
2013-08~2016-12,中国科学院昆明植物研究所, 博士后

专利与奖励

   
专利成果
[1] 黄胜雄, 纪旭, 颜一军, 杨静, 罗剑英. 一种罗博卢酮的生物合成基因簇及其应用. CN: CN106636141B, 2019-08-13.
[2] 黄胜雄, 纪旭, 颜一军, 杨静, 罗剑英. 一种托酚酮类化合物及其药物组合物和其制备方法与应用. 中国: CN105585573B, 2018-04-17.
[3] 黄胜雄, 汪香婷, 杨静, 杨瑞敏, 张秀磊, 颜一军. α‑吡喃酮类化合物及其药物组合物和其在制药中的应用. 中国: CN107266406A, 2017.10.20.

出版信息

   
发表论文
[1] Yan, Yijun, Yu, Zhiyin, Zhong, Wei, Hou, Xiaodong, Tao, Qiaoqiao, Cao, Minhang, Wang, Li, Cai, Xiaofeng, Rao, Yijian, Huang, ShengXiong. Characterization of Multifunctional and Non-stereoselective Oxidoreductase RubE7/IstO, Expanding the Functional Diversity of the Flavoenzyme Superfamily. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, [2] Qiu, Fei, Yan, Yijun, Zeng, Junlan, Huang, JianPing, Zeng, Lingjiang, Zhong, Wei, Lan, Xiaozhong, Chen, Min, Huang, ShengXiong, Liao, Zhihua. Biochemical and Metabolic Insights into Hyoscyamine Dehydrogenase. ACS CATALYSIS[J]. 2021, 11(5): 2912-2924, http://dx.doi.org/10.1021/acscatal.0c04667.
[3] Yu, Zhiyin, Han, Chuanyu, Yu, Bing, Zhao, Junwei, Yan, Yijun, Huang, Shengxiong, Liu, Chongxi, Xiang, Wensheng. Taxonomic Characterization, and Secondary Metabolite Analysis of Streptomyces triticiradicis sp. nov.: A Novel Actinomycete with Antifungal Activity. MICROORGANISMS[J]. 2020, 8(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000514650700082.
[4] Wang YongJiang, Wang Li, He Xin, Xu DongDong, Tang Jun, Ma YaTuan, Yan YiJun, Gu YuCheng, Yang Jing, Huang ShengXiong. Characterization of inthomycin biosynthetic gene cluster revealing new insights into carboxamide formation. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2020, 18(9): 677-683, http://dx.doi.org/10.1016/S1875-5364(20)60006-1.
[5] Yang, FengXian, Huang, JianPing, Liu, Zhixiang, Wang, Zhiyan, Yang, Jing, Tang, Jun, Yu, Zhiyin, Yan, Yijun, Kai, Guoyin, Huang, ShengXiong. Benwamycins A-G, Trialkyl-Substituted Benzene Derivatives from a Soil-Derived Streptomyces. JOURNAL OF NATURAL PRODUCTS[J]. 2020, 83(1): 111-117, https://www.webofscience.com/wos/woscc/full-record/WOS:000510076700015.
[6] Yan, Yijun, Yang, Jing, Wang, Li, Xu, Dongdong, Yu, Zhiyin, Guo, Xiaowei, Horsman, Geoff P, Lin, Shuangjun, Tao, Meifeng, Huang, ShengXiong. Biosynthetic access to the rare antiarose sugar via an unusual reductase-epimerase. CHEMICAL SCIENCE[J]. 2020, 11(15): 3959-3964, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152690/.
[7] Zhang, Zhouxin, Cao, Pei, Shang, NingNing, Yang, Jing, Wang, Li, Yan, Yijun, Huang, ShengXiong. Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces. ORGANIC CHEMISTRY FRONTIERS[J]. 2019, 6(2): 177-182, http://ir.kib.ac.cn/handle/151853/64226.
[8] Su, Can, Yan, Yijun, Guo, Xiaowei, Luo, Jianying, Liu, Chongxi, Zhang, Zhouxin, Xiang, WenSheng, Huang, ShengXiong. Characterization of the N-methyltransferases involved in the biosynthesis of toxoflavin, fervenulin and reumycin from Streptomyces hiroshimensis ATCC53615. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2019, 17(3): 477-481, https://www.webofscience.com/wos/woscc/full-record/WOS:000458578900007.
[9] Dong, Miao, Cao, Pei, Ma, YaTuan, Luo, Jianying, Yan, Yijun, Li, RongTao, Huang, ShengXiong. A new actinomycin Z analogue with an additional oxygen bridge between chromophore and beta-depsipentapeptide from Streptomyces sp. KIB-H714. NATURAL PRODUCT RESEARCH[J]. 2019, 33(2): 219-225, [10] Wang, Li, Yan, Yijun, Huang, Jianping, Xiong, Zi-Jun, Yang, Jing, Li, Jie, Huang, Sheng-Xiong, Wang, Zhiyan, Luo, Jianying. Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces. JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 83(8): 4867-4870, http://ir.kib.ac.cn/handle/151853/63378.
[11] Yang, FengXian, Hou, GuanXiong, Luo, Jianying, Yang, Jing, Yan, Yijun, Huang, ShengXiong. New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318. JOURNAL OF ANTIBIOTICS[J]. 2018, 71(12): 1040-1043, http://ir.kib.ac.cn/handle/151853/64674.
[12] Shang, NingNing, Zhang, Zhouxin, Huang, JianPing, Wang, Li, Luo, Jianying, Yang, Jing, Peng, Teng, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong. Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity. JOURNAL OF ANTIBIOTICS[J]. 2018, 71(7): 672-676, http://ir.kib.ac.cn/handle/151853/64722.
[13] Huang, Sheng-Xiong, Yang, Feng-Xian, Luo, Jianying, Hou, Guan-Xiong, Yang, Jing, Yan, Yijun. New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318. CANCERS[J]. 2018, 10(11): 449-, http://www.irgrid.ac.cn/handle/1471x/1781670.
[14] Yang, Jing, Peng, Teng, Yan, Yijun, Huang, Sheng-Xiong, Ma, Ya-Tuan, Shang, Ning-Ning, Zhang, Zhouxin, Huang, Jian-Ping, Wang, Li, Luo, Jianying. Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity. NATURAL PRODUCT COMMUNICATIONS[J]. 2018, 13(7): 795-798, http://ir.kib.ac.cn/handle/151853/63350.
[15] Xiong, ZiJun, Huang, Jianping, Yan, Yijun, Wang, Li, Wang, Zhiyan, Yang, Jing, Luo, Jianying, Li, Jie, Huang, ShengXiong. Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces. ORGANIC CHEMISTRY FRONTIERS[J]. 2018, 5(8): 1272-1279, http://ir.kib.ac.cn/handle/151853/64747.
[16] Wang, Li, Yang, Jing, Kong, LingMei, Deng, Jun, Xiong, Zijun, Huang, Jianping, Luo, Jianping, Yan, Yijun, Hu, Yikao, Li, XiaoNian, Li, Yan, Zhao, Yong, Huang, ShengXiong. Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor. ORGANIC LETTERS[J]. 2017, 19(14): 3911-3914, https://www.webofscience.com/wos/woscc/full-record/WOS:000406356500057.
[17] Yang, Ruimin, Yang, Jing, Wang, Li, Huang, JianPing, Xiong, Zijun, Luo, Jianying, Yu, Mingming, Yan, Yijun, Huang, ShengXiong. Lorneic Acid Analogues from an Endophytic Actinomycete. JOURNAL OF NATURAL PRODUCTS[J]. 2017, 80(10): 2615-2619, https://www.webofscience.com/wos/woscc/full-record/WOS:000414234400004.
[18] RuiMin Yang, XiuLei Zhang, Li Wang, JianPing Huang, Jing Yang, YiJun Yan, JianYing Luo, XiangTing Wang, ShengXiong Huang. α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells. NAT. PROD. BIOPROSPECT.[J]. 2017, 7: 329–334-, http://ir.kib.ac.cn/handle/151853/54995.
[19] Yijun Yan, Jing Yang, Zhiyin Yu, Mingming Yu, YaTuan Ma, Li Wang, Can Su, Jianying Luo, Geoffrey P Horsman, ShengXiong Huang. Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids. NATURE COMMUNICATIONS[J]. 2016, 7(1): http://ir.kib.ac.cn/handle/151853/33643.
[20] Yan, Yijun, Ma, YaTuan, Yang, Jing, Horsman, Geoff P, Luo, Dan, Ji, Xu, Huang, ShengXiong. Tropolone Ring Construction in the Biosynthesis of Rubrolone B, a Cationic Tropolone Alkaloid from Endophytic Streptomyces. ORGANIC LETTERS[J]. 2016, 18(6): 1254-1257, http://ir.kib.ac.cn/handle/151853/26179.
[21] Yu, Zhiyin, Wang, Li, Yang, Jing, Zhang, Fan, Sun, Yun, Yu, Mingming, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong. A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin. TETRAHEDRON LETTERS[J]. 2016, 57(12): 1375-1378, http://dx.doi.org/10.1016/j.tetlet.2016.02.061.
[22] 喻明明, 苏灿, 马亚团, 颜一军, 黄胜雄, 薛大权. 土壤来源链霉菌KIB-H91次级代谢产物的分离鉴定. 天然产物研究与开发[J]. 2015, 27(6): 1003-1006, http://ir.kib.ac.cn/handle/151853/25805.
[23] Zhang, Ji, Yan, YiJun, An, Jing, Huang, ShengXiong, Wang, XiangJing, Xiang, WenSheng. Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase. MICROBIAL CELL FACTORIES[J]. 2015, 14(1): http://www.irgrid.ac.cn/handle/1471x/1028961.
[24] Cao, Pei, Yang, Jing, Miao, CuiPing, Yan, Yijun, Ma, YaTuan, Li, XiaoNian, Zhao, LiXing, Huang, ShengXiong. New Duclauxamide from Penicillium manginii YIM PH30375 and Structure Revision of the Duclauxin Family. ORGANIC LETTERS[J]. 2015, 17(5): 1146-1149, http://www.irgrid.ac.cn/handle/1471x/959041.
[25] Huang Sheng-Xiong, Wang Xiang-Jing, Yan Yijun, Wang Ji-Dong, Zhang Ji, Liu Cong-Xi, Xiang Wen-Sheng, Shen Ben. Neaumycin - A New Macrolide from Streptomyces sp. NEAU-x211. ORG. LETT[J]. 2012, 1254-1257, http://www.irgrid.ac.cn/handle/1471x/834321.

科研活动

   
科研项目
( 1 ) 罗博卢酮类天然产物稀有糖基的合成,转移及结构多样性研究, 主持, 国家级, 2021-01--2024-12
( 2 ) 三七根际微生物活性天然产物的发现与生物合成, 主持, 部委级, 2020-01--2022-12
( 3 ) 基于lipstatin组合生物合成的胰脂肪酶抑制剂的研究, 主持, 省级, 2019-10--2022-09
( 4 ) 云南省“****”青年人才入选者科研项目支持经费, 主持, 省级, 2019-01--2023-12
( 5 ) 青年创新促进会支持经费, 主持, 部委级, 2018-01--2021-12