鱼类发育生物学与生物技术学

   

071007-遗传学
090801-水产养殖

鱼类配子发生与胚胎发育
鱼类遗传育种学

1997-09--2002-09   中国科学院水生生物研究所   博士学位
1993-09--1997-06   武汉大学   学士学位

博士研究生

博士

2019.3-今：中国科学院水生生物研究所，鱼类发育生物技术学科组组长、国家水生生物种质资源库主任、研究员

2010.12-今：中国科学院水生生物研究所，鱼类发育生物技术学科组组长、国家斑马鱼资源中心主任、研究员

2009. 10- 2009. 12：美国弗吉尼亚大学，细胞生物学系，客座副教授（Visiting Associate Professor）

2006. 9-2008. 3：法国国家科研中心分子细胞及遗传学研究所（IGBMC/CNRS），发育生物学研究中心，法中科学及应用基金会（FFCSA）博士后访问学者

2005. 1 -2010. 11：中国科学院水生生物研究所，副研究员

2002. 7-2004. 12：中国科学院水生生物研究所，助理研究员

2022-06-13-今,国际斑马鱼学会, 理事，亚洲区代表
2020-09-01-今,遗传, 编委
2019-08-01-今,中国动物学会, 理事
2019-01-01-今,激光生物学报, 常务编委
2016-09-23-今,中国动物学会斑马鱼分会, 副理事长兼秘书长
2016-05-31-今,湖北省实验动物学会, 常务理事
2014-12-31-今,湖北省遗传学会, 理事
2014-12-31-今,中国青年科技工作者协会, 会员
2014-12-31-今,中国科学院青年联合会, 委员
2011-12-31-今,中国科学院青年创新促进会, 会员

水产遗传育种学
水产生物遗传育种学
水产生物发育生物学
水产动物发育生物生物学
鱼类发育生物学
鱼类基因工程

   

（1） 国家杰出青年科学基金, 国家级, 2020
（2） 首届中国水产青年科技奖, 国家级, 2016
（3） 中国科学院青年创新促进会优秀会员, , 院级, 2016
（4） 首届国家自然科学基金委优秀青年科学基金, , 国家级, 2012
（5） 中国科学院卢嘉锡青年人才奖, , 院级, 2010
（6） 法中科学及应用基金会FFCSA, , 其他, 2006

[1] 王厚鹏, 孙永华, 何牡丹, 叶鼎, 王小四. 一种基于靶点内回文序列介导的MMEJ靶向基因组修饰方法和应用. CN: CN113684212A, 2021-11-23.

[2] 李玲璐, 潘鲁湲, 谢训卫, 易震宇, 孙永华. 一种实验动物精子冻存库管理系统. CN: CN113393189A, 2021-09-14.

[3] 叶鼎, 孙永华, 张泉清, 何牡丹, 王厚鹏. 一种可标记鱼类生殖干细胞的多克隆抗体的制备方法. CN: CN113173988A, 2021-07-27.

[4] 潘鲁湲, 张昀, 李玲璐, 李阔宇, 柳力月, 谢训卫, 熊凤, 孙永华. 一种斑马鱼实验管理系统. CN: CN113112221A, 2021-07-13.

[5] 李阔宇, 孙永华. 一种斑马鱼鱼苗养殖的装置. CN: CN211268169U, 2020-08-18.

[6] 袁丽, 杨小红, 李依, 叶鼎, 孙永华, 韩丹翔, 胡强. 螺旋藻γ-亚麻酸的新用途. CN: CN109893520A, 2019-06-18.

[7] 熊凤, 孙永华, 叶鼎, 朱作言. 一种用于原始生殖细胞靶向突变的转基因载体及制备方法和用途. CN: CN105274141A, 2016-01-27.

[8] 孙永华, 庞少臣, 王厚鹏, 朱作言, 康景轩. 一种提高鱼类omega-3多不饱和脂肪酸的方法及应用. CN: CN103898159A, 2014-07-02.

[9] 孙永华, 熊凤, 魏志强, 朱作言. 一种定向筛选同源重组PGC的载体及构建方法和应用. CN: CN103397046A, 2013-11-20.

[10] 孙永华, 熊凤, 魏志强, 朱作言. 一种高效标记斑马鱼PGC的载体及转基因鱼的制备方法和用途. CN: CN103224955A, 2013-07-31.

[11] 孙永华, 朱作言, 熊凤, 伊斯提亚克, 迈克沃特斯. 一种鱼类持续激活生长激素受体基因及制备方法和用途. CN: CN102241763A, 2011-11-16.

   

[1] Ding Ye, Tao Liu, Yongming Li, Yaping Wang, Wei Hu, Zuoyan Zhu, Yonghua Sun. Identification of fish spermatogenic cells through high-throughput immunofluorescence against testis with an antibody set. FRONTIERS IN ENDOCRINOLOGY[J]. 2023, 14: https://doaj.org/article/1e115f05f22240139655fadc3b121b04.
[2] Xu, ShanShan, Li, Yi, Wang, HouPeng, Chen, WenBo, Wang, YaQing, Song, ZiWei, Liu, Hui, Zhong, Shan, Sun, YongHua. Depletion of stearoyl-CoA desaturase (scd) leads to fatty liver disease and defective mating behavior in zebrafish. ZOOLOGICAL RESEARCH[J]. 2023, 44(1): 63-77, http://dx.doi.org/10.24272/j.issn.2095-8137.2022.167.
[3] 孙永华. Endogenous biosynthesis of docosahexaenoic acid (DHA) regulates fish oocyte maturation by promoting pregnenolone production. ZOOLOGICAL RESEARCH[J]. 2023, [4] Zhang, Ru, Tu, YiXuan, Ye, Ding, Gu, Zhenglong, Chen, ZhenXia, Sun, Yonghua. A Germline-Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells. ADVANCED SCIENCE[J]. 2022, 9(36): http://dx.doi.org/10.1002/advs.202203631.
[5] Xiao, Yao, Jiao, Shengbo, He, Miao, Lin, Da, Zuo, Huanyan, Han, Jiahao, Sun, Yonghua, Cao, Gang, Chen, Zhi, Liu, Huan. Chromatin conformation of human oral epithelium can identify orofacial cleft missing functional variants. INTERNATIONAL JOURNAL OF ORAL SCIENCE[J]. 2022, 14(1): 497-508, http://dx.doi.org/10.1038/s41368-022-00194-0.
[6] 柳力月, 潘鲁湲, 孙永华. 斑马鱼“裂头病”病原的分离与鉴定及常见疾病诊断. 生物化学与生物物理进展[J]. 2022, 49(5): 917-927, http://lib.cqvip.com/Qikan/Article/Detail?id=7107379304.
[7] Tao, Binbin, Hu, Hongling, Chen, Ji, Chen, Lu, Luo, Daji, Sun, Yonghua, Ge, Feng, Zhu, Zuoyan, Trudeau, Vance L, Hu, Wei. Sinhcaf-dependent histone deacetylation is essential for primordial germ cell specification. EMBO REPORTS[J]. 2022, 23(6): http://dx.doi.org/10.15252/embr.202154387.
[8] 孙永华, 胡炜. 重要养殖鱼类生物育种技术研究. 中国农业科技导报[J]. 2022, 24(12): 120-128, http://lib.cqvip.com/Qikan/Article/Detail?id=7108903115.
[9] He, Mudan, Jiao, Shengbo, Zhang, Ru, Ye, Ding, Wang，Houpeng, Sun, YongHua. Translational control by maternal Nanog promotes oogenesis and early embryonic development. Development[J]. 2022, [10] Zhang, Fenghua, Hao, Yongkang, Li, Xianmei, Li, Yi, Ye, Ding, Zhang, Ru, Wang, Xiaosi, He, Mudan, Wang, Houpeng, Zhu, Zuoyan, Sun, Yonghua. Surrogate production of genome-edited sperm from a different subfamily by spermatogonial stem cell transplantation. SCIENCE CHINA-LIFE SCIENCES[J]. 2022, 65(5): 969-987, https://www.sciengine.com/doi/10.1007/s11427-021-1989-9.
[11] Xie, Haibo, Wang, Xiaosi, Jin, Minjun, Li, Lanqin, Zhu, Junwen, Kang, Yunsi, Chen, Zhe, Sun, Yonghua, Zhao, Chengtian. Cilia regulate meiotic recombination in zebrafish. JOURNAL OF MOLECULAR CELL BIOLOGY[J]. 2022, 14(7): http://dx.doi.org/10.1093/jmcb/mjac049.
[12] 孙永华. Cyp11a2 Is Essential for Oocyte Development and Spermatogonial Stem Cell Differentiation in Zebrafish. Endocrinology[J]. 2022, [13] Ding Ye, YiXuan Tu, Houpeng Wang, Mudan He, Yaqing Wang, Zhengfang Chen, ZhenXia Chen, Yonghua Sun. A landscape of differentiated biological processes involved in the initiation of sex differentiation in zebrafish. WATER BIOLOGY AND SECURITY[J]. 2022, 1(3): 100059-87, http://lib.cqvip.com/Qikan/Article/Detail?id=7108051614.
[14] Yousef Mohammed, Ding Ye, Mudan He, Houpeng Wang, Yanhua Li, Danxiang Han, Zuoyan Zhu, Yonghua Sun. Induction of biosynthesis of ketocarotenoid from β-carotene in fish embryos. AQUACULTURE[J]. 2021, 542: http://dx.doi.org/10.1016/j.aquaculture.2021.736863.
[15] 孙永华. Manipulating and Visualizing the Germline with Transgenic lines. Methods in Molecular Biology. 2021, [16] Mohammed, Yousef, Ye, Ding, He, Mudan, Wang, Houpeng, Li, Yanhua, Han, Danxiang, Zhu, Zuoyan, Sun, Yonghua. Induction of biosynthesis of ketocarotenoid from 8-carotene in fish embryos. AQUACULTURE[J]. 2021, 542: http://dx.doi.org/10.1016/j.aquaculture.2021.736863.
[17] Sun, Yonghua, Zhang, Bo, Luo, Lingfei, Shi, DeLi, Wang, Han, Cui, Zongbin, Huang, Honghui, Cao, Ying, Shu, Xiaodong, Zhang, Wenqing, Zhou, Jianfeng, Li, Yun, Du, Jiulin, Zhao, Qingshun, Chen, Jun, Zhong, Hanbing, Zhong, Tao P, Li, Li, Xiong, JingWei, Peng, Jinrong, Xiao, Wuhan, Zhang, Jian, Yao, Jihua, Yin, Zhan, Mo, Xianming, Peng, Gang, Zhu, Jun, Chen, Yan, Zhou, Yong, Liu, Dong, Pan, Weijun, Zhang, Yiyue, Ruan, Hua, Liu, Feng, Zhu, Zuoyan, Meng, Anming, Sun, Yonghua, Pan, Luyuan, Wang, Houpeng, Xie, Weixun, He, Mudan, Ye, Ding, Li, Kuoyu, Xiong, Feng, Liu, Liyue, Li, Linglu, Zhang, Yun, Zhang, Bo, Liu, Da, Cheng, Zhenchao, Hu, Yingying, Wu, Qian, Luo, Zhou, Zhang, Yutian, Wu, Yingdan, Li, Wenyuan, Luo, Lingfei, Ma, Jianlong, Mo, Dashuang, Cai, Pengcheng, Chen, Jinzi, Sun, Junhui, Zhou, Yang, Wu, Chuan, Ni, Rui, Shi, DeLi, Shao, Ming, Zhang, YanJun, Feng, LiJun, Cheng, XiaoNing, Li, JiTong, Xing, YanYi, Zhang, Yan, Meng, YaPing, Yu, BeiBei, Wang, Han, Huang, Jian, Zhang, Shuqing, Ji, Cheng, Tan, Yicheng, Wang, Jingjing, Zhang, Fanmiao, Wang, Mingyong, Huang, Guodong, Zhong, Zhaomin, Zhang, Wei, Cui, Zongbin, Long, Yong, Song, Guili, Li, Xiaohui, Li, Xixi, Chen, Kai, Ren, Jing, Yan, Junjun, Li, Qing, Huang, Honghui, Ruan, Hua, Zhu, Shicheng, Chen, Xuejiao, Pan, Jingjing, Jiang, Faming, Chen, Jiehui, Huang, Chao, Dong, Guoping, Yi, Xiaogui, Cao, Ying, Hu, Ruikun, Huang, Weilai, Liu, Jiangfang, Hong WangXiao, Shu, Dong, Xia, Jianhong, Zhao, Shaoyang, Wang, Pengtao, Wu, Xiuhua, Zhang, Wenqing, Zhang, Yiyue, Xu, Mengchang, Liu, Wei, Huang, Zhibing, Lin, Qing, Wu, Mei, Zhou, Jianfeng, Sheng, Aibo, Tang, Peipei, Gong, Xiaoxia, Mou, Wei, Zu, Congcong, Li, Yun, Lu, Ling, Liu, Yunzhang, Rong, Xiaozhi, Chen, Jianyang, Du, Jiulin, Bu, Jiwen, Du, Xufei, Liu, Tingting, Gu, Shanye, Zhao, Qingshun, Dong, Zhangji, Dong, Xiaohua, Cao, Shasha, Yue, Yunyun, Gu, Chun, Liu, Meijing, Chen, Jun, Gong, Hongjian, Zhong, Hanbing, Yang, Xuanjun, Chen, Jiahao, Xu, Qiushi, Zhong, Tao P, Jin, Daqin, She, Peilu, Sun, Jianjian, Lai, Kaa Seng, Li, Li, Zhang, Yu, Shi, Yanyan, Zhao, Fangying, Xiong, JingWei, Pang, Meijun, Gao, Lu, Lei, Lei, Peng, Jinrong, Lo, Jane, Xiao, Wuhan, Cai, Xiaolian, Ouyang, Gang, Zhang, Jian, Ma, Weirui, Miao, Liyun, Yao, Jihua, Hu, Yu, Yin, Zhan, Mo, Xianming, Li, Xue, Peng, Gang, Zhang, Cuizhen, Wang, Fenghua, Zhu, Jun, Yang, Ruimeng, Yuan, Hao, Chen, Yan, Pan, Yi, Zhou, Yong, Liu, Dong, Zhao, Feng, Pan, Weijun, Liu, Feng, Ding, Yanyan, Xue, Yuanyuan, Wang, Lu, Zhang, Yifan, Ma, Dongyuan, Lu, Xinyan, Gao, Shuai, Xia, Jun, Zhu, Zuoyan, Meng, Anming, Liu, Xingfeng, Qiu, Juhui, Gong, Bo, Chen, Luxi, Xiong, Cong, Yao, Likun, Xing, Cencan, Wang, Yixia, Shen, Weimin, Sun, Jiawei, ZAKOC Consortium. Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. GENOME RESEARCH[J]. 2020, 30(1): 118-126, http://dx.doi.org/10.1101/gr.248559.119.
[18] Li, Xianmei, Zhang, Fenghua, Wu, Nan, Ye, Ding, Wang, Yaqing, Zhang, Xiaofan, Sun, Yonghua, Zhang, YongAn. A critical role of foxp3a-positive regulatory T cells in maintaining immune homeostasis in zebrafish testis development. JOURNAL OF GENETICS AND GENOMICS[J]. 2020, 47(9): 547-561, http://lib.cqvip.com/Qikan/Article/Detail?id=7104394665.
[19] Feng, Ke, Cui, Xuefan, Song, Yanlong, Tao, Binbin, Chen, Ji, Wang, Jing, Liu, Shaojun, Sun, Yonghua, Zhu, Zuoyan, Trudeau, Vance L, Hu, Wei. Gnrh3 Regulates PGC Proliferation and Sex Differentiation in Developing Zebrafish. ENDOCRINOLOGY[J]. 2020, 161(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000518155500008.
[20] 李阔宇, 潘鲁湲, 孙永华. 斑马鱼鱼房和养殖系统建设标准. 中国比较医学杂志[J]. 2020, 30(6): 121-127, http://lib.cqvip.com/Qikan/Article/Detail?id=7102201984.
[21] Liu, Chengjie, Ye, Ding, Wang, Houpeng, He, Mudan, Sun, Yonghua. Elovl2 But Not Elovl5 Is Essential for the Biosynthesis of Docosahexaenoic Acid (DHA) in Zebrafish: Insight from a Comparative Gene Knockout Study. MARINE BIOTECHNOLOGY[J]. 2020, 22(5): 613-619, http://dx.doi.org/10.1007/s10126-020-09992-1.
[22] Zhang, Qifeng, Ye, Ding, Wang, Houpeng, Wang, Yaqing, Hu, Wei, Sun, Yonghua. Zebrafish cyp11c1 Knockout Reveals the Roles of 11-ketotestosterone and Cortisol in Sexual Development and Reproduction. ENDOCRINOLOGY[J]. 2020, 161(6): https://www.webofscience.com/wos/woscc/full-record/WOS:000540717900002.
[23] 张昀, 潘鲁湲, 李阔宇, 谢训卫, 熊凤, 柳力月, 李玲璐, 孙永华. 斑马鱼常用信息网络及数据库建设进展. 计算机产品与流通[J]. 2020, 121-122, http://lib.cqvip.com/Qikan/Article/Detail?id=00002FUDK9787JP0MPDO5JL16HR.
[24] He, Mudan, Zhang, Ru, Jiao, Shengbo, Zhang, Fenghua, Ye, Ding, Wang, Houpeng, Sun, Yonghua. Nanog safeguards early embryogenesis against global activation of maternal beta-catenin activity by interfering with TCF factors. PLOS BIOLOGY[J]. 2020, 18(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000596578100001.
[25] Mudan He, Ru Zhang, Shengbo Jiao, Fenghua Zhang, Ding Ye, Houpeng Wang, Yonghua Sun. Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors.. PLOS BIOLOGY[J]. 2020, 18(7): https://doaj.org/article/e8b104d5cd564f478f74480005c4a9fa.
[26] 孙永华. Proliferation and Sex Differentiation in Developing Zebrafish.. Endocrinology. 2020, [27] Xianmei Li, Fenghua Zhang, Nan Wu, Ding Ye, Yaqing Wang, Xiaofan Zhang, Yonghua Sun, Yong-An Zhang. A critical role of foxp3a-positive Treg cells in maintaining immune homeostasis in zebrafish testis development.. Journal of Genetics and Genomics[J]. 2020, [28] Jiang, Jue, Wang, Jingchao, Yue, Ming, Cai, Xiaolian, Wang, Tianci, Wu, Chao, Su, Hexiu, Wang, Yanwu, Han, Meng, Zhang, Yingchi, Zhu, Xiaofan, Jiang, Peng, Li, Peng, Sun, Yonghua, Xiao, Wuhan, Feng, Hui, Qing, Guoliang, Liu, Hudan. Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis. CANCER CELL[J]. 2020, 37(2): 200-+, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321798/.
[29] Zhang, Fenghua, Li, Xianmei, He, Mudan, Ye, Ding, Xiong, Feng, Amin, Golpour, Zhu, Zuoyan, Sun, Yonghua. Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted primordial germ cells. JOURNAL OF GENETICS AND GENOMICS[J]. 2020, 47(1): 37-47, http://lib.cqvip.com/Qikan/Article/Detail?id=7101666717.
[30] Sun, Yonghua, Zhu, Zuoyan. Designing future farmed fishes using genome editing. SCIENCE CHINA-LIFE SCIENCES[J]. 2019, 62(3): 420-422, http://lib.cqvip.com/Qikan/Article/Detail?id=7001721043.
[31] Tian, Jing, Shao, Jinhui, Liu, Cong, Hou, HsinYu, Chou, ChihWei, Shboul, Mohammad, Li, GuoQing, ElKhateeb, Mohammad, Samarah, Omar Q, Kou, Yao, Chen, YuHsuan, Chen, MeiJen, Lyu, Zhaojie, Chen, WeiLeng, Chen, YuFu, Sun, YongHua, Liu, YiWen. Deficiency of lrp4 in zebrafish and human LRP4 mutation induce aberrant activation of Jagged-Notch signaling in fin and limb development. CELLULAR AND MOLECULAR LIFE SCIENCES[J]. 2019, 76(1): 163-178, http://dx.doi.org/10.1007/s00018-018-2928-3.
[32] 黄思雨, 何牡丹, 王厚鹏, 孙永华. 斑马鱼ints12的CRISPR/Cas9敲除及其对UsnRNA剪接的调控. 水生生物学报[J]. 2019, 43(1): 1-8, http://lib.cqvip.com/Qikan/Article/Detail?id=7001048483.
[33] Zhang, Xiaofan, Pang, Shaochen, Liu, Chengjie, Wang, Houpeng, Ye, Ding, Zhu, Zuoyan, Sun, Yonghua. A Novel Dietary Source of EPA and DHA: Metabolic Engineering of an Important Freshwater SpeciesCommon Carp by fat1-Transgenesis. MARINE BIOTECHNOLOGY[J]. 2019, 21(2): 171-185, [34] Ye, Ding, Zhu, Lin, Zhang, Qifeng, Xiong, Feng, Wang, Houpeng, Wang, Xiaosi, He, Mudan, Zhu, Zuoyan, Sun, Yonghua. Abundance of Early Embryonic Primordial Germ Cells Promotes Zebrafish Female Differentiation as Revealedby Lifetime Labeling of Germline. MARINE BIOTECHNOLOGY[J]. 2019, 21(2): 217-228, https://www.webofscience.com/wos/woscc/full-record/WOS:000462935700009.
[35] Ding Ye, Xiaosi Wang, Changyong Wei, Mudan He, Houpeng Wang, Yanwu Wang, Zuoyan Zhu, Yonghua Sun. Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b.. PLOS GENETICS[J]. 2019, 15(9): https://doaj.org/article/a49ec30e315046f7b617c2c42e1d0f46.
[36] Yonghua Sun, Zuoyan Zhu. Designing future farmed fishes using genome editing. 中国科学:生命科学英文版[J]. 2019, 62(3): 420-422, http://lib.cqvip.com/Qikan/Article/Detail?id=7001721043.
[37] Yang, Xiaohong, Li, Yi, Li, Yanhua, Ye, Ding, Yuan, Li, Sun, Yonghua, Han, Danxiang, Hu, Qiang. Solid Matrix-Supported Supercritical CO2 Enhances Extraction of -Linolenic Acid from the Cyanobacterium Arthrospira (Spirulina) platensis and Bioactivity Evaluation of the Molecule in Zebrafish. MARINE DRUGS[J]. 2019, 17(4): [38] Peng Xu, Jian Xu, Guangjian Liu, Lin Chen, Zhixiong Zhou, Wenzhu Peng, Yanliang Jiang, Zixia Zhao, Zhiying Jia, Yonghua Sun, Yidi Wu, Baohua Chen, Fei Pu, Jianxin Feng, Jing Luo, Jing Chai, Hanyuan Zhang, Hui Wang, Chuanju Dong, Wenkai Jiang, Xiaowen Sun. The allotetraploid origin and asymmetrical genome evolution of the common carp Cyprinus carpio. NATURE COMMUNICATIONS[J]. 2019, 10(1): http://dx.doi.org/10.1038/s41467-019-12644-1.
[39] Chen Minjie, Zhang Jie, Pang Shaochen, Wang Chang, Wang Ling, Sun Yonghua, Song Maoyong, Liang Yong. Evaluating estrogenic and anti-estrogenic effect of endocrine disrupting chemicals (EDCs) by zebrafish ( Danio rerio ) embryo-based vitellogenin 1 ( vtg1 ) mRNA expression. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART C: TOXICOLOGY & PHARMACOLOGY[J]. 2018, [40] 李玲璐, 熊凤, 谢训卫, 潘鲁媛, 李阔宇, 柳力月, 张昀, 孙永华. 国家斑马鱼资源中心的资源、技术和服务建设. 遗传[J]. 2018, 40(8): 683-692, http://lib.cqvip.com/Qikan/Article/Detail?id=7000780180.
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（1） 基因资源与现代渔业, Gene resources and current fisheries, 中国科学技术出版社, 2010-07, 第 1 作者
（2） 鱼类转基因研究中几个观念的转变和鱼类原始生殖细胞操作, PGC manipulation in fishes, 中国科学技术出版社 , 2012-11, 第 1 作者
（3） Manipulating and Visualizing the Germline with Transgenic Lines, Springer Nature, 2021-08, 第 1 作者

（ 1 ） 基于鱼类分子设计育种的基因操作技术研究, 主持, 国家级, 2010-01--2014-12
（ 2 ） 斑马鱼资源的收集、整理和利用, 主持, 部委级, 2012-01--2016-12
（ 3 ） 模式动物斑马鱼, 主持, 国家级, 2013-01--2015-12
（ 4 ） 原始生殖细胞发育和分化的调控网络研究, 主持, 部委级, 2013-09--2018-07
（ 5 ） 中韩生物资源开发和信息交流双边研讨会, 主持, 国家级, 2015-09--2015-12
（ 6 ） 中国科学院模式和特色动物实验, 主持, 部委级, 2014-01--2018-06
（ 7 ） 国家斑马鱼资源平台, 主持, 省级, 2015-01--2018-12
（ 8 ） 国家斑马鱼资源中心运营, 主持, 市地级, 2015-07--2018-12
（ 9 ） 功能基因育种潜力的验证与新育种技术研究, 主持, 国家级, 2014-01--2015-12
（ 10 ） 鱼类品种改良快速、定向的基因操作技术基础研究, 主持, 国家级, 2004-01--2008-12
（ 11 ） 利用基因敲除斑马鱼模型研究Nanog抑制Wnt/β-catenin信号通路的分子调控机制, 主持, 国家级, 2017-01--2020-12
（ 12 ） 鱼类分子遗传育种, 参与, 国家级, 2018-01--2023-12
（ 13 ） 斑马鱼发育与代谢突变体库的系统创制, 主持, 国家级, 2019-09--2024-08
（ 14 ） 利用DHA合成缺陷和富余模型研究DHA对鱼类生殖质形成的作用机制, 主持, 国家级, 2020-01--2023-12
（ 15 ） 鱼类生殖细胞发育与生物技术, 主持, 国家级, 2021-01--2025-12

已指导学生

杨明宇  硕士研究生  071007-遗传学  

于力群  硕士研究生  071007-遗传学  

魏志强  硕士研究生  071007-遗传学  

朱林  硕士研究生  071007-遗传学  

张筱帆  博士研究生  071007-遗传学  

黄思雨  硕士研究生  071007-遗传学  

刘成杰  博士研究生  071007-遗传学  

张茹  博士研究生  071007-遗传学  

王亚青  博士研究生  071007-遗传学  

现指导学生

李依  博士研究生  071007-遗传学  

陈正芳  博士研究生  071007-遗传学  

焦圣博  博士研究生  071007-遗传学  

苏乃克  硕士研究生  071007-遗传学  

张泉清  博士研究生  071007-遗传学  

郝永康  博士研究生  071007-遗传学  

何丽佳  硕士研究生  090801-水产养殖  

邓家杰  博士研究生  071007-遗传学  

李雪徽  博士研究生  071007-遗传学  

曾江  硕士研究生  086000-生物与医药