基本信息
朱之光  男  博导  中国科学院天津工业生物技术研究所
电子邮件: zhu_zg@tib.cas.cn
通信地址: 天津空港经济区西七道32号
邮政编码:

招生信息

   
招生专业
081703-生物化工
招生方向
生物能源,生物燃料电池,生物催化,体外合成生物学,生物电化学,生物纳米技术

教育背景

2009-08--2013-05   美国弗吉尼亚理工大学   博士
2007-08--2009-05   美国弗吉尼亚理工大学   硕士
2003-09--2007-06   华中科技大学   学士

专利与奖励

  • Zhang Y-H.Percival, Zhu      Zhiguang. Complete oxidation of sugars to electricity by using      cell-free synthetic enzymatic pathways. 美国发明专利US10128552B2,      2018/11/13
  • Zhang Y-H.Percival, Zhu Zhiguang.      Complete oxidation of sugars to electricity by using cell-free      synthetic enzymatic pathways. 欧洲发明专利EP3005461B1,      2018/12/09
  • 张以恒;朱之光,使用无细胞合成酶促通路将糖完全氧化成电能      CN104471771B, 2018/12/07
  • 朱之光;吴晓亮;张以恒;马晖,可瞬时充电的酶燃料电池 CN105932307B,      2018/06/12
  • 朱之光;张以恒;马晖;吴晓亮,体外生物燃料电池嵌入式供电系统 CN105914387B,      2018/05/29
  • 朱之光;张以恒;宋海燕,一种酶电极、生物传感器及其制备方法和用途 201811109488.6


奖励信息
(1) 国家优秀自费留学生奖学金, 国家级, 2012

出版信息

33. Wu RR, Ma Chunling, Yong Yang-Chun, Zhang Y-HP, Zhu ZG*. 2019. Composition and distribution of internal resistance in an enzymatic fuel cell and its dependence on cell design and operating conditions. RSC Advances 9:7292-7300

32.   Kang ZP, Zhang Y-HP, Zhu ZG*. 2019. A shriveled rectangular carbon tube with the concave surface for high-performance enzymatic glucose/O2 biofuel cells. Biosensors and Bioelectronics 132:76-83

31.   Song HY, Ma CL, Zhou W, You C, Zhang Y-HP, Zhu ZG*. 2018. Construction of enzyme-cofactor/mediator conjugates for enhanced in vitro bioelectricity generation. Bioconjugate Chemistry 29:3993-3998

30.   Wu RR, Zhu ZG*. 2018. Self-powered enzymatic electrosynthesis of l-3,4-dihydroxyphenylalanine in a hybrid bioelectrochemical system. ACS Sustainable Chemistry Engineering 6:12593-12597

29.   Zhu ZG*, You C, Ma YH, Zhang Y-HP. 2018. In vitro synthetic enzymatic biosystems at the interface of the food-energy-water nexus: A conceptual framework and recent advances. Process Biochemistry 74:43-49

28.   Meng DD, Wei XL, Zhang Y-HP, Zhu ZG, You C, Ma YH. 2018. Stoichiometric Conversion of Cellulosic Biomass by in Vitro Synthetic Enzymatic Biosystems for Biomanufacturing. ACS Catalysis 8:9550-9559

27.   Zhou W, Huang R, Zhu ZG*, Zhang Y-HP*. 2018. Coevolution of both thermostability and activity of polyphosphate glucokinase from Thermobifida fusca YX. Applied & Environmental Microbiology 84:e01224-18

26.   Wu RR, Ma CL, Zhang Y-HP, Zhu ZG*. 2018. Complete oxidation of xylose for bioelectricity generation by reconstructing a bacterial xylose utilization pathway in vitro. ChemCatChem 10:2030-2035

25.   Zhu ZG*, Ma CL, Zhang Y-HP. 2018. Co-utilization of mixed sugars in an enzymatic fuel cell based on an in vitro enzymatic pathway. Electrochimica Acta 263:184-191

24.   You C, Huang R, Wei XL, Zhu ZG, Zhang Y-HP. 2017. Protein engineering of oxidoreductases utilizing nicotinamide-based coenzymes, with applications in synthetic biology. Synthetic and Systems Biotechnology 2:208-218

23.   Zhu ZG, Zhang Y-HP. 2017. In vitro metabolic engineering of bioelectricity generation by the complete oxidation of glucose. Metabolic Engineering 39:110-116

22.   Chen H#, Zhu ZG#, Huang R, Zhang Y-HP. 2016. Coenzyme engineering of a hyperthermophilic 6-phosphogluconate dehydrogenase from NADP+ to NAD+ with its application to biobatteries. Scientific Reports 6:36311 (#co-first author)

21.   Moustafa HMA, Kim E, Zhu ZG, Wu CH, Zaghloul TI, Adams MWW, Zhang Y-HP. 2016. Water splitting for high-yield hydrogen production energized by biomass xylooligosaccharides catalyzed by an enzyme cocktail. ChemCatChem 8:2898-2902

20.   Zhu ZG, Zhang Y-HP. 2015. Use of nonimmobilized enzymes and mediators achieved high power densities in closed biobatteries. Energy Science & Engineering 3:490-497

19.   Zhu ZG, Tam TK, Sun FF, You C, Zhang Y-HP. 2014. A high-energy-density sugar biobattery based on a synthetic enzymatic pathway. Nature Communications 5:3026

18.   Zhu ZG, Tam TK, Zhang Y-HP. 2013. Cell-free biosystems in the production of electricity and bioenergy. Advances in Biochemical Engineering/Biotechnology 137:125-152

17.   Zhu ZG, Sun FF, Zhang XZ, Zhang Y-HP. 2012. Deep oxidation of glucose in enzymatic fuel cells through a non-natural synthetic enzymatic pathway containing a cascade of two thermostable dehydrogenases. Biosensors and Bioelectronics 36: 110-115

16.   Sathisuksanoh N, Zhu ZG, Zhang Y-HP. 2012. Cellulose solvent- and organic solvent-based lignocellulose fractionation enabled efficient sugar release from a variety of lignocellulosic feedstocks. Bioresource Technology 117:228-233

15.   Sathisuksanoh N, Zhu ZG, Zhang Y-HP. 2012. Cellulose solvent-based pretreatment for corn stover and avicel: concentrated phosphoric acid versus ionic liquid [BMIM] Cl. Cellulose, 19:1161-1172

14.   Wang QQ, He ZB, Zhu ZG, Zhang Y-HP, Ni YH, Luo XL, Zhu JY. 2012. Evaluation of cellulose accessibilities of lignocelluloses by solute exclusion and protein adsorption techniques. Biotechnology and Bioengineering 109: 381-389

13.   Zhu ZG, Wang YR, Minteer SD, Zhang Y-HP. 2011. Maltodextrin-powered enzymatic fuel cell through a non-natural enzymatic pathway. Journal of Power Sources 196:7505-7509

12.   Zhang XZ, Sathitsuksanoh N, Zhu ZG, Zhang Y-HP. 2011. One-step production of lactate from cellulose as sole carbon source without any other organic nutrient by recombinant cellulolytic Bacillus subtilis. Metabolic Engineering 13:364-372

11.   Ye X, Zhu ZG, Zhang CM, Zhang Y-HP. 2011. Fusion of a Family 9 carbohydrate-binding module improves the catalytic potential of Clostridium thermocellum cellodextrin phosphorylase on cellulosic materials. Applied Microbiology and Biotechnology 92:551-560

10.   Zhang Y-HP, Myung SW, You C, Zhu ZG, Rollin J. 2011. Toward low-cost biomanufacturing through in vitro synthetic biology: bottom-up design. Journal of Materials Chemistry 21: 18877-18886

9.       Wang YR, Huang WD, Sathisuksanoh N, Zhu ZG, Zhang Y-HP. 2011. Biohydrogenation from biomass sugar mediated by cell-free synthetic pathway biotransformation. Chemistry and Biology 18: 372-380

8.       Sathisuksanoh N, Zhu ZG, Zhang Y-HP. 2011. Cellulose solvent-based pretreatment breaks highly ordered hydrogen bonds in cellulose fibers of switchgrass. Biotechnology and Bioengineering 108:521-529

7.       Rollin J, Zhu ZG, Sathisuksanoh N, Zhang Y-HP. 2011. Increasing substrate accessibility is more important than removing lignin: A comparison of cellulose solvent-based lignocellulose fractionation and soaking in aqueous ammonia. Biotechnology and Bioengineering 108: 22-30

6.       Sathitsuksanoh N, Zhu ZG, Ho TJ, Bai MD, Zhang Y-HP. 2010. Bamboo saccharification through cellulose solvent-based biomass pretreatment followed by enzymatic hydrolysis at ultra-low cellulase loadings. Bioresource Technology 101:4926-4929

5.       Zhang XZ, Zhang ZM, Zhu ZG, Sathitsuksanoh N, Yang D, Zhang Y-HP2010.  The non-cellulosomal family 48 cellobiohydrolase from Clostridium phytofermentans ISDg: Heterologous expression, characterization, and processivity.  Applied Microbiology and Biotechnology 86: 525-533

4.       Zhu ZG, Sathitsuksanoh N, Vinzant T, Schell DJ, McMillan JD, Zhang Y-HP. 2009. Comparative study of corn stover pretreated by dilute acid and cellulose solvent-based lignocellulose fractionation: Enzymatic hydrolysis, supramolecular structure, and substrate accessibility. Biotechnology and Bioengineering 103: 715-724

3.       Zhu ZG, Sathitsuksanoh N, Zhang Y-HP. 2009. Direct quantitative determination of adsorbed cellulase on lignocellulosic biomass with its application to study cellulase desorption for potential recycling. Analyst 134:2267-2272

2.       Sathitsuksanoh N, Zhu ZG, Templeton N, Rollin J, Harvey S, Zhang Y-HP. 2009. Saccharification of a potential bioenergy crop, Phragmites australis (common reed), by lignocellulose fractionation followed by enzymatic hydrolysis at decreased cellulase loadings. Industrial & Engineering Chemistry Research 48:6441-6447

1.       Moxley G, Zhu ZG, Zhang Y-HP. 2008. Efficient sugar release by the cellulose solvent-based lignocellulose fractionation technology and enzymatic cellulose hydrolysis. Journal of Agriculture and Food Chemistry 56: 7885–7890


发表著作
(1) Chapter 4. Chemical Biotechnology of in vitro Biosystems for Biomanufacturing, RSC Publishing, 2014-05, 第 1 作者

科研活动

·         国家自然科学基金面上项目 体外无细胞多酶催化途径中电子传递模块的人工设计与组装 21878324 负责人 2019/01-2022/12

·         国家自然科学基金青年项目 基于多酶催化的生物质燃料电池的构筑研究 21706273 负责人 2018/01-2020/12

·         中国科学院重点部署项目 二氧化碳的人工生物转化 ZDRW-ZS-2016-3S 子课题负责人2017/07-2018/12

·         中国科学院****C类启动经费2017/01-2018/12