基本信息
邹国安  男  博导  中国科学院新疆理化技术研究所
电子邮件: gazou@ms.xjb.ac.cn
通信地址: 新疆 乌鲁木齐市 北京南路40-1号
邮政编码: 830011

研究领域

植物资源化学,包括民族特色药用植物活性成分及质量分析研究

招生信息

   
招生专业
070303-有机化学
100701-药物化学
招生方向
天然有机化学
天然药物化学

教育背景

2006-09--2009-07   北京协和医学院 清华大学   博士学位
2003-09--2006-06   湖北中医学院   硕士学位
1999-09--2003-06   湖北中医学院   学士学位
学历
研究生
学位
博士

工作经历

   
工作简历
2018-11~现在, 中国科学院新疆理化技术研究所, 研究员
2015-12~2016-12,美国德克萨斯大学休斯顿健康科学中心, 访问学者
2009-10~2018-10,中国科学院新疆理化技术研究所, 副研究员
2009-08~2009-09,中国科学院新疆理化技术研究所, 助理研究员

专利与奖励

   
奖励信息
(1) 新疆自治区科学技术进步奖, 一等奖, 省级, 2015
专利成果
( 1 ) 一种骆驼刺花瓣乙酸乙酯部位的用途, 发明专利, 2016, 第 3 作者, 专利号: 201610339435.8

出版信息

   
发表论文
[1] He, Cheng‐Hui, Lv, Jia‐Min, Khan, Ghulam Jilany, Duan, Hong, Wang, Wei, Zhai, Ke‐Feng, Zou, Guo-An, Aisa, Haji Akber. Total flavonoid extract from Dracocephalum moldavica L. improves pulmonary fibrosis by reducing inflammation and inhibiting the hedgehog signaling pathway. Phytotherapy Research[J]. 2023, 24(5): 4780- 4780, https://doi.org/10.1002/ptr.7771.
[2] Jumai, Aikebaier, Zou, GuoAn, Liu, Geyu, Aisa, Haji Akber. Pyrrolizidine alkaloids from Jacobaea vulgaris Gaertn and theoretical studies on intramolecular interactions. NATURAL PRODUCT RESEARCH[J]. 2023, https://doi.org/10.1080/14786419.2023.2174533.
[3] Liu, Changhai, Nueraihemaiti, Mayire, Zang, Deng, Edirs, Salamet, Zou, Guoan, Aisa, Haji Akber. Quercetin 3-O-(6″-O-E-caffeoyl)-β-D-glucopyranoside, a Flavonoid Compound, Promotes Melanogenesis through the Upregulation of MAPKs and Akt/GSK3β/β-Catenin Signaling Pathways. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2023, 24(5): https://doi.org/10.3390/ijms24054780.
[4] Zhao, Yanrong, Zou, Guoan, Aisa, Haji Akber. Guaianolides and unusual 3-oxa-guaianolides from Artemisia macrocephala. PHYTOCHEMISTRY[J]. 2022, 197(5): http://doi.org/10.1016/j.phytochem.2024.113108.
[5] Jun-Fang Wu, Ablajan Turak, Deng Zang, Guo-An Zou, Haji Akber Aisa. Sesquiterpenoids from Seriphidium transiliense and Their Melanogenic Activity. JOURNAL OF NATURAL PRODUCTS[J]. 2022, 85(11): 2570-2582, https://doi.org/10.1021/acs.jnatprod.2c00527.
[6] Wu, J F, Turak, A, Rouzimaimaiti, R, Zou, G A, Aisa, H A. Monoterpenoids from Seriphidium transiliense and their Biological Activity. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2022, 58(1): 32-36, https://doi.org/10.1007/s10600-022-03635-8.
[7] Ablajan, Nurfida, Zhao, Bo, Wenjuan, Xue, Zhao, Jiangyu, Sagdullaev, Sh Sh, Guoan, Zou, Aisa, Haji Akber. Chemical components of Aconitum barbatum var. puberulum and their cytotoxic and antibacterial activities. NATURAL PRODUCT RESEARCH[J]. 2021, https://doi.org/10.1080/14786419.2021.2005050.
[8] Jumai, Aikebaier, Rouzimaimaiti, Ruxianguli, Zou, GuoAn, Aisa, Haji Akber. Pyrrolizidine alkaloids and unusual millingtojanine A-B from Jacobaea vulgaris (syn. Senecio jacobaea L.). PHYTOCHEMISTRY[J]. 2021, 190(10): http://doi.org/10.1016/j.phytochem.2021.112862.
[9] Qiao, MengFei, Wang, Ying, Li, Lei, Hu, GuangZhi, Zou, GuoAn, Mamat, Xamxikamar, Dong, YeMin, Hu, Xun. Self-templated nitrogen-doped mesoporous carbon decorated with double transition-metal active sites for enhanced oxygen electrode catalysis. RARE METALS[J]. 2020, 39(7): 824-833, http://doi.org/10.1007/s12598-019-01345-9.
[10] Qiao, Mengfei, Wang, Ying, Wagberg, Thomas, Mamat, Xamxikamar, Hu, Xun, Zou, Guoan, Hu, Guangzhi. Ni?Co bimetallic coordination effect for long lifetime rechargeable Zn?air battery. JOURNAL OF ENERGY CHEMISTRY[J]. 2020, 47(8): 146-154, https://doi.org/10.1016/j.jechem.2019.12.005.
[11] Qiao, Mengfei, Wang, Ying, Mamat, Xamxikamar, Chen, Anran, Zou, Guoan, Li, Lei, Hu, Guangzhi, Zhang, Shusheng, Hu, Xun, Voiry, Damien. Rational Design of Hierarchical, Porous, Co-Supported, N-Doped Carbon Architectures as Electrocatalyst for Oxygen Reduction. CHEMSUSCHEM[J]. 2020, 13(4): 741-748, http://doi.org/10.1002/cssc.201903053.
[12] Cui, J, Nuermaimaiti, M, Zou, G, Xin, X. Chemical Composition of Artemisia sieversiana. CHEMISTRYOFNATURALCOMPOUNDS[J]. 2020, 56(6): 1120-1121, https://doi.org/10.1007/s10600-020-03241-6.
[13] Muratova, M S, Zou, G A, Jenis, J, Aisa, H A. Chemical Constituents of Alhagi sparsifolia. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2019, 55(5): 932-933, https://doi.org/10.1007/s10600-019-02850-0.
[14] Jia, F Y, Turak, A, Zou, G A. New Phthalide from Helichrysum arenarium. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2019, 55(6): 999-1001, https://doi.org/10.1007/s10600-019-02878-2.
[15] Turghun, Ch, Bakri, M, Zou, G A, Bobakulov, Kh M, Aisa, H A. PHENOLIC COMPOUNDS FROM LEAVES OF Nitraria sibirica. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2018, 54(5): 987-989, https://doi.org/10.1007/s10600-018-2530-9.
[16] Chen, QiBin, Gao, Jie, Zou, GuoAn, Xin, XueLei, Aisa, Haji Akber. Piperidine Alkaloids with Diverse Skeletons from Anacyclus pyrethrum. JOURNAL OF NATURAL PRODUCTS[J]. 2018, 81(6): 1474-1482, https://doi.org/10.1021/acs.jnatprod.8b00239.
[17] Guo, D, Xue, W J, Zou, G A, Aisa, H A. Chemical Composition of Alhagi sparsifolia Flowers. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2016, 52(6): 1095-1097, https://doi.org/10.1007/s10600-016-1871-5.
[18] Zou, G A, Guo, D, Zhao, H Q, Aisa, H A. Bioactive Constituents of Ziziphora clinopodioides. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2015, 51(5): 961-963, http://doi.org/10.1007/s10600-015-1462-x.
[19] 赛那瓦尔·芒思尔, 张戈, 邹国安, 阿吉艾克拜尔·艾萨. 骆驼刺中异鼠李素-3-O-β-D芸香糖苷对照品的制备研究. 新疆医科大学学报[J]. 2014, 37(1): 44-46, http://lib.cqvip.com/Qikan/Article/Detail?id=48434270.
[20] Zou, G A, Wang, Y, Zou, Z M, Chen, S. Lignans from stems of Croton caudatus var. tomentosus. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2013, 49(1): 93-94, https://doi.org/10.1007/s10600-013-0515-2.
[21] 赛那瓦尔芒思尔, 阿里木江阿布力孜, 邹国安. 骆驼刺高效液相指纹图谱研究. 干旱区研究[J]. 2013, 30(5): 873-876, https://doi.org/10.13866/j.azr.2013.05.005.
[22] Ye, Yuhua, Bahang, Liu, Yongqiang, Zou, Guoan, Aisa, Haji Akber. Chemical constituents of Ziziphora clinopodioides (a). CHEMISTRY OF NATURAL COMPOUNDS[J]. 2012, 48(4): 681-682, http://doi.org/10.1007/s10600-012-0348-4.
[23] Zou, G A, Aisa, H A, Zhang, H W, Yang, J S, Zou, Z M. CHEMICAL COMPOSITION OF Croton laevigatus. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2012, 47(6): 993-994, http://doi.org/10.1007/s10600-012-0126-3.
[24] Xu, F, Zou, G A, Liu, Y Q, Aisa, H A. Chemical constituents from seeds of Lactuca sativa. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2012, 48(4): 574-576, https://doi.org/10.1007/s10600-012-0314-1.
[25] Zou, G A, Mansur, S, Hu, S C, Aisa, H A, Shakhidoyatov, Kh M. Pyrrole alkaloids from Alhagi sparsifolia. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2012, 48(4): 635-637, https://doi.org/10.1007/s10600-012-0330-1.
[26] Zou, G A, Aisa, H A, Zhang, H W, Yang, J S, Zou, Z M, Shakhidoyatov, Kh M. Flavonoids from Croton laevigatus. CHEMISTRY OF NATURAL COMPOUNDS[J]. 2012, 48(4): 687-688, https://doi.org/10.1007/s10600-012-0351-9.
[27] Zou, GuoAn, Zhang, HongWu, Aisa, Haji Akber, Yang, JunShan, Peng, ChaoZhong, Zou, ZhongMei. Laevigatbenzoate from Croton laevigatus Vahl.. JOURNAL OF NATURAL MEDICINES[J]. 2011, 65(2): 391-394, https://doi.org/10.1007/s11418-010-0503-9.
[28] Su, ZhiHeng, Li, ShuQi, Zou, GuoAn, Yu, ChangYuan, Sun, YanGuo, Zhang, HongWu, Gu, Ying, Zou, ZhongMei. Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2011, 55(3): 533-539, http://doi.org/10.1016/j.jpba.2011.02.013.
[29] Su, ZhiHeng, Zou, GuoAn, Preiss, Alfred, Zhang, HongWu, Zou, ZhongMei. Online identification of the antioxidant constituents of traditional Chinese medicine formula Chaihu-Shu-Gan-San by LC-LTQ-Orbitrap mass spectrometry and microplate spectrophotometer. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2010, 53(3): 454-461, http://doi.org/10.1016/j.jpba.2010.05.014.
[30] Zou, GuoAn, Su, ZhiHeng, Zhang, HongWu, Wang, Yuan, Yang, JunShan, Zou, ZhongMei. Flavonoids from the stems of Croton caudatus Geisel. var. tomentosus Hook. (Euphorbiaceae). Molecules[J]. 2010, http://doi.org/10.3390/molecules15031097.
[31] Zou, GuoAn, Ding, Gang, Su, ZhiHeng, Yang, JunShan, Zhang, HoneWu, Peng, ChaoZhong, Aisa, Haiji Akber, Zou, ZhongMei. Lactonecembranoids from Croton laevigatus. JOURNAL OF NATURAL PRODUCTS[J]. 2010, 73(4): 792-795, http://doi.org/10.1021/np100044t.
[32] Yang, Q R, Wu, H Z, Wang, X M, Zou, G A, Liu, Y W. Three new diterpenoids from Coleus forskohlii Briq. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH[J]. 2006, 8(4): 355-360, http://doi.org/10.1080/10286020500172236.

科研活动

   
科研项目
( 1 ) 维药芳香新塔花降压活性成分研究, 负责人, 国家任务, 2012-01--2014-12
( 2 ) 骆驼刺化学成分及质量分析研究, 负责人, 中国科学院计划, 2009-09--2013-08
( 3 ) 沙棘质量标准提高及综合利用研究, 参与, 国家任务, 2011-01--2014-12
( 4 ) 8种维药药材化学对照品的制备, 参与, 地方任务, 2010-04--2012-12
( 5 ) 棉花花等五个品种质量标准提高, 参与, 地方任务, 2010-03--2011-03
( 6 ) 民族药质量标准研究技术平台, 参与, 国家任务, 2011-01--2011-12
( 7 ) 民族药药效物质基础分离分析技术平台, 参与, 国家任务, 2012-01--2012-12
( 8 ) 维吾尔药标准品的制备及质量标准研究, 负责人, 地方任务, 2010-05--2014-04
( 9 ) 治疗白癜风创新维药研制, 参与, 研究所自选, 2012-10--2017-12
( 10 ) 两种新疆道地药材降糖活性研究, 参与, 地方任务, 2013-01--2015-12
( 11 ) 民族药生物活性筛选与代谢技术平台, 参与, 国家任务, 2015-01--2016-12
( 12 ) 中国科学院中亚药物研发中心, 参与, 中国科学院计划, 2019-01--2019-12
( 13 ) 中亚地区药用资源发掘与持续利用, 参与, 研究所自选, 2016-01--2020-12
( 14 ) 中亚特色阿魏抗白癜风活性成分及其成药性研究, 负责人, 中国科学院计划, 2021-01--2023-12
( 15 ) 撒马尔罕阿魏倍半萜香豆素成分及其生物活性研究, 负责人, 地方任务, 2021-01--2023-12
( 16 ) 自治区天山英才, 负责人, 地方任务, 2021-01--2023-12
参与会议
(1)Chemical constituents of Ferula samarcandica and pharmacological effect of feshurin on vitiligo in vitro.   Nueraihemaiti M, Kamoldinov K, Zang D, Zou GA, Aisa HA   2022-11-19
(2)Haplophyllum griffithianum – a source of quinolone alkaloids.    Kodirova DR, Rasulova KA, Sagdullaev SS, Zou GA, Aisa HA.    2022-11-19
(3) Phytochemicals from Ferula samarkandica Korovin.   Zhang MM, Kamoldinov K, Kodirova DR, Aisa HA, Zou GA.    2022-11-19
(4)Quinoline alkaloids from Haplophyllum acutifolium.   Jumai A, Kodirova DR, Kamoldinov K, Li J, Zou GA, Aisa HA.    2022-11-19
(5)Sesquiterpenoids from Seriphidium transiliense.    Wu JF, Turak A, Zou GA, Zhao JY, Aisa HA.    2022-11-19
(6)Cytotoxic activities of phytochemicals from Ferula species.    G. Turdu, Kh. Sh. Kamoldinov, J. Li, D. Tang, J. F. Wu, D. R. Kodirova, Kh. M. Bobakulov, L. Jiang, G. A. Zou*.    2021-10-07
(7)Diterpenoid alkaloids from Aconitum barbatum var. Puberulum.    N. Ablajan, Bo Zhao, Jiangyu Zhao, Sh. Sh. Sagdullaev, Guoan Zou, H. A. Aisa*.   2021-10-07
(8) Effect of Ferula samarkandica on melanin synthesis and protein expression in B16 melanoma cells.    Kh. Sh. Kamoldinov, D. Zang, J. F. Wu, A. Kawuli, D. Tuerhong, N. Rustamova, N. R. Mukhamedov, G. A. Zou, J. Dou*.   2021-10-07
(9)Sesquiterpene coumarins from the roots of Ferula samarkandica.   Kh. Sh. Kamoldinov, J. Li, A. Jumai, P. Ainiwaer, H. L. Li, Y. R. Zhao, R. Abdulla, G. A. Zou*.   2021-10-07
(10)Sesquiterpenes from Artemisia macrocephala Jacq. ex Bess.   Y. R. Zhao, A. Turak, H. A. Aisa, G. A. Zou*.   2021-10-07
(11) Chemical composition of n-BuOH part from Alhagi Sparsifolia flowers.   第六届可食和药用植物资源及功能成分国际学术研讨会   Merey Muratova, H. A. Aisa, G.A. Zou   2018-10-14
(12)Lignins from the leaves of Nitraria sibirica.   第六届可食和药用植物资源及功能成分国际学术研讨会   2018-10-14
(13)Terpenoids from the aerial parts of Ferula feruloides.    第六届可食和药用植物资源及功能成分国际学术研讨会   2018-10-14
(14)塔城翠雀花中二萜生物碱的研究   中国化学会第31届学术年会   2018-05-05
(15)Diterpenoid alkaloids from Delphinium pseudoaemulans C. Y. Yang.    2017-09-07
(16)Diterpenoid alkaloids from Delphinium pseudoaemulans C.Y.Yang   第五届可食植物资源及活性成分国际学术研讨会   W. J. Xue, B. Zhao   2016-11-04
(17)Antihypertensive activity of Ziziphora clinopodioides Lam.   第11届天然化合物化学国际研讨会   Guo Dan, Maidinuer Aini, Duolikun, Lin Jianbo, Zou Guoan.   2015-10-01
(18)Antioxidants from Ziziphora clinopodioides Lam. by combination of chromatographic techniques   第11届天然化合物化学国际研讨会   Guo Dan, Rahima Abdulla, Luo Yuqin, Zou Guoan.   2015-10-01
(19)Quality Standard of Alhagi sparsifolia by HPLC Fingerprint   第三届可食植物资源及活性成分国际学术研讨会   Sanawar Mansur, Alimujiang Abulizi, Gou-An Zou, Haji Akber Aisa.    2012-07-28
(20)Studies on chemical constituents of ziziphora clinopodioides   第九届天然化合物化学国际研讨会   Yu-Hua Ye, Hang Ba, Guo-An Zou   2011-10-16
(21) Isomeric Reference Substances Preparation of Isorhamnetin-3-O--D-glucosyl-(61)-α-L-rhamnoside and Isorhamnetin-3-O--D-galactosyl-(61)-α-L-rhamnoside from Alhagi sparsifolia   第九届天然化合物化学国际研讨会   Sanawar Mansur, Ke-Fei Han, Amatjan Ayupbek, Guo-An Zou   2011-10-16
(22)Chemical constituents from leaves of Croton laevigatus   第九届天然化合物化学国际研讨会   Guo-An Zou, Haji Akber Aisa, Jun-Shan Yang, Zhong-Mei Zou.   2011-10-16
(23)Cembrane Diterpenes from Croton laevigatus   第二届可食植物资源及活性成分国际学术研讨会   Zou Guo-An, Ding Gang, Su Zhi-Heng, Yang Jun-Shan, Zhang Hong-Wu, Peng Chao-Zhong, Haji Akber Aisa, Zou Zhong-Mei.   2010-07-28

指导学生

已指导学生

郭丹  硕士研究生  078001-药物化学  

乔孟飞  硕士研究生  080501-材料物理与化学  

贾芳怡  硕士研究生  078001-药物化学  

吴俊芳  硕士研究生  070303-有机化学  

赵艳荣  硕士研究生  070303-有机化学  

现指导学生

帕孜莱提·艾尼瓦尔  博士研究生  070303-有机化学  

何承辉  博士研究生  070303-有机化学  

闫德峰  博士研究生  070303-有机化学  

迪娜·波拉提  博士研究生  070303-有机化学  

阮景辉  博士研究生  070303-有机化学  

阿丽屯古丽·库尔班  博士研究生  070303-有机化学  

宋雨晴  硕士研究生  070303-有机化学  

张苗苗  博士研究生  070303-有机化学