Jia Liu, male
Professor of Biomedical Engineering
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
Address: No.1068 Xueyuan Avenue, Xili shenzhen university town, Nanshan district, Shenzhen
Zip code: 518055
Mathematical Modeling of Physiological System
Research and Development of Physiological Signal Measurement System
2002~2006: Ph.D. in Biomedical Engineering, University of Southampton, United Kingdom
Thesis: “A Study of the Variability of Cerebral Autoregulation Using Modeling Techniques”
1998~2002: B.Sc. in Computer Science and Technology, East China University of Science and Technology, China
Deputy Director of Laboratory of Engineering and Scientific Computing
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences (SIAT)
2009~2015: Associate Professor
Assistant to Director of the Institute
2006~2009: Assistant Professor
2013~Current: Adjunct Professor (Honorary)
Department of Medicine and Therapeutics, the Chinese University of Hong Kong
 Guo ZN, Guo WT, J. Liu, Chang J, Ma H, Zhang P, Zhang FL, Han K, Hu HH, Jin H, Sun X. “Changes in cerebral autoregulation and blood biomarkers after remote ischemic preconditioning”. Neurology. 2019 29:10-212.
 Feng X, Chan KL, Lan L, Abrigo J, J. Liu, Fang H, Xu Y, Soo Y, Leng X, Leung TW. “Stroke Mechanisms in Symptomatic Intracranial Atherosclerotic Disease: Classification and Clinical Implications.” Stroke. 2019;50(10):2692-9.
 R. Zi, J. Liu*, L. Gu and X. Ge, “Enabling Security and High Energy Efficiency in the Internet of Things With Massive MIMO Hybrid Precoding”, IEEE Internet of Things Journal, 6:5, 8615-8625, 2019.
 K. L. Chan, X. Leng, W. Zhang, W. Dong, Q. Qiu, J. Yang, J. Liu*, “Early Identification of High-Risk TIA or Minor Stroke Using Artificial Neural Network”, Frontiers in Neurology, 2019,10:171.
 S. Lv, Z. N. Guo, H. Jin, X. Sun, M. Jia, H. Ma, Y. Lv, Q. Qiu, J. Liu*, Y. Yang*, “Compromised dynamic cerebral autoregulation in patients with epilepsy”, BioMed research international, 2018.
 Z. N. Guo, X. Sun, J. Liu, H. Sun, Y. Zhao, H. Ma, B. Xu, Z. Wang, C. Li, X. Yan, H. Zhou, “The impact of variational primary collaterals on cerebral autoregulation. Frontiers in physiology”, 2018, 9:759.
 Leng X, Lan L, Ip HL, Fan F, Ma SH, Ma K, Liu H, Yan Z, J. Liu, Abrigo J, Soo YO. Translesional pressure gradient and leptomeningeal collateral status in symptomatic middle cerebral artery stenosis. European journal of neurology. 2018 Feb;25(2):404-10.
 Z. N. Guo, H. Jin, H. Sun, Y. Zhao, J. Liu, H. Ma, X. Sun, Y. Yang, “Antioxidant Melatonin: potential functions in improving cerebral autoregulation after subarachnoid hemorrhage”, Frontiers in physiology, 2018, 9.
 L. Liu, J. Ding, X. Leng, Y. Pu, L. A. Huang, A. Xu, K. S. Wong, X. Wang, Y. Wang, …, J. Liu, “Guidelines for evaluation and management of cerebral collateral circulation in ischaemic stroke 2017”, Stroke and vascular neurology, 2018, 3: 117-130.
 H. Y. Ma, Z. N. Guo, H. Jin, X. L. Yan, J. Liu, S. Lv, P. Zhang, X. Sun, Y. Yang, “Preliminary study of dynamic cerebral autoregulation in acute ischemic stroke: association with clinical factors”, Frontiers in neurology, 2018, 9.
 Guo ZN, Lv S, J. Liu, Wang Z, Jin H, Qiu Q, Sun X, Yang Y. Compromised dynamic cerebral autoregulation in patients with generalized anxiety disorder: a study using transfer function analysis. BMC psychiatry. 2018 Dec;18(1):164.
 W. T. Guo, H. Y. Ma, J. Liu, Z. N. Guo, Y. Yang, “Dynamic Cerebral Autoregulation Remains Stable During the Daytime (8 am to 8 pm) in Healthy Adults”, Frontiers in physiology, 2018, 9: 1642.
 L. Xiong, G. Tian, W. Lin, W. Wang, L. Wang, T. Leung, V. Mok, J. Liu*, X. Chen*, K.S. Wong, “Is Dynamic Cerebral Autoregulation Bilaterally Impaired after Unilateral Acute Ischemic Stroke?” Journal of Stroke and Cerebrovascular Diseases, 2017 , 26 (5) :1081.
 L. Xiong, X. Liu, T. Shang, P. Smielewski, J. Donnelly, Z.N Guo, Y. Yang, T. Leung, M. Czosnyka, R. Zhang, J. Liu*, K. S. Wong*, “Impaired cerebral autoregulation: measurement and application to stroke”, Journal of Neurology Neurosurgery & Psychiatry, 2017 , 88 (6) :520.
 J. Liu, Z. Yan, Y. Pu, W.S. Shiu, J. Wu, R. Chen, X. Leng, H. Qin, X. Liu, B. Jia, L. Song, Y. Wang, Z. Miao, Y. Wang, L. Liu*, X.C. Cai, “Functional assessment of cerebral artery stenosis: A pilot study based on computational fluid dynamics”, Journal of Cerebral Blood Flow & Metabolism, 2017,10:1-10.
 H. Y. Ma#, Z. N. Guo#, J. Liu#, Y. Q. Xing, R. Zhao, Y. Yang*, “Temporal Course of Dynamic Cerebra Autoregulation in Patients With Intracerebral Hemorrhage”, Stroke, 2016.
 X. Liu*, G. Wang, and J. Liu, "An Adaptive Real-time Beat Detection Method for Continuous Pressure Signals." Journal of Clinical Monitoring and Computing, 2016.
 Z.-N. Guo, A. Shao A, L.S. Tong, W. Sun, L. Liu, Y. Yang, "The Role of Nitric Oxide and Sympathetic Control in Cerebral Autoregulation in the Setting of Subarachnoid Hemorrhage and Traumatic Brain Injury. " Molecular Neurobiology, 2015.
 S. Wang#, Z.N. Guo#, Y. Q. Xing, H. Y. Ma, H. Jin, J. Liu*,Y. Yang*, “Dynamic Cerebral Autoregulation in Asymptomatic Patients With Unilateral Middle Cerebral Artery Stenosis”, Medicine, 2015.
 Z.N. Guo#, Y.Q. Xing#, S. Wang, H.Y. Ma, J. Liu*, Y. Yang*, “Characteristics of Dynamic Cerebral Autoregulation in Cerebral Small Vessel Disease: Diffuse and Sustained”, Scientific Reports, 2015.
 J. Liu*, D. M. Simpson, H. Kouchakpour, R. B. Panerai, J. Chen, S. Gao, P. Zhang, and X. Wu, “Rapid pressure-to-flow dynamics of cerebral autoregulation induced by instantaneous changes of arterial CO2,” Medical Engineering & Physics, 2014.
 Z.-N. Guo, Y. Xing, J. Liu, S. Yan, H. Jin, and Y. Yang*, “Compromised cerebral autoregulation in right to left shunt: a mechanism of migraine and stroke,” PLoS ONE, 2014.
 Z.-N. Guo, J. Liu, Y. Xing, S. Yan, C. Lv, H. Jin, and Y. Yang*, “Dynamic cerebral autoregulation is heterogeneous in different subtypes of acute ischemic stroke,” PLoS ONE, 2014.
 N. Angarita-Jaimes*, H. Kouchakpour, J. Liu, R. B. Panerai, and D. M. Simpson, “Optimising the assessment of cerebral autoregulation from black box models,” Medical Engineering & Physics. 2014
 J. Chen, J. Liu*, W.-H. Xu, R. Xu, B. Hou, L.-Y. Cui, and S. Gao*, “Impaired Dynamic Cerebral Autoregulation and Cerebrovascular Reactivity in Middle Cerebral Artery Stenosis,” PLoS ONE, 2014.
 X. Gong, J. Liu*, P. Dong, P. Zhang, N. Li, X. Zhao, and Y. Wang*, “Assessment of Dynamic Cerebral Autoregulation in Patients with Basilar Artery Stenosis,” PLoS ONE, 2013.
 J. Chen, J. Liu*, L. Duan, R. Xu, Y.-Q. Han, W.-H. Xu, L.-Y. Cu, and S. Gao*, "Impaired dynamic cerebral autoregulation in Moyamoya disease," CNS Neuroscience & Therapeutics, 2013.
 X. Liu, G. Wang*, and J. Liu, "Wideband model of on-chip CMOS interconnects using space-mapping technique," International Journal of RF and Microwave Computer-Aided Engineering, 2011.
 J. Liu*, D. M. Simpson, and R. Allen, "Tracking time-varying cerebral autoregulation in response to changes in respiratory PaCO2," Physiological Measurement, 2010.
 J. Yan, Y. Lu, J. Liu*, X. Wu, and Y. Xu, "Self-adaptive model-based ECG denoising using features extracted by mean shift algorithm," Biomedical Signal Processing and Control, 2010.
 J. Yan, Y. Lu, J. Liu*, X. Wu, and Y. Xu, "Intelligent diagnosis of cardiovascular diseases utilizing ECG signals," International Journal of Information Acquisition, 2010.
 J. Liu*, D. M. Simpson, and R. Allen, "High spontaneous fluctuation in arterial blood pressure improves the assessment of cerebral autoregulation," Physiological Measurement, 2005.
 An External counterstroke control system and an External counterstroke control method, 2009. Patent for invention. Author NO.3. Patent number: China. Application number: 200910238808.2. Public number: 102106778A
 A Physiological Signal Quality Assessment System and Method, 2010. Patent for invention. Author NO.1. Patent number: : ZL201010192921.4
 A Physiological Signal Quality Sssessment System and Method, 2010. Patent for invention. Author NO.1. Patent number: United Kingdom. Application number: PCT/cn2010/074925
 An External Counterpulsation Actuator, 2010. Patent for utility models. Author NO.1. Patent number: China. Application number: 201020117395.0. Public number: 201609478U
 An Extracorporeal Counterpulsation Actuator, 2009. Patent for invention. Author NO.1. Patent number: China. Application number: 200910105958.6. Public number: 101543456.
 An External Counterpulsation Device and an External Counterpulsation Signal Control Method, 2010. Patent for invention. Author NO.1. Patent number: China. Application number: 201010113125.7
 An antithrombotic device, 2015. Patent for utility models. Author NO.1. Patent number: zl201520175964.x
 A Pneumatic Connection Device, 2015. Patent for invention. Author NO.1. Patent number: 201410837664.3
 A Blood Pressure Measurement System and its operation method, 2016. Patent for invention. Author NO.1. Patent number: 201610389536.6
 A Blood Pressure Measuring Instrument, 2016. Patent for invention. Author NO.1. Patent number: ZL201710610887.7
 A Blood Pressure Measuring Instrument, 2016, Patent for invention. Author NO.1. Patent number: 201620534583.0
 A Blood Pressure Measurement System, 2016. Patent for invention. Author NO.1. Patent number: 201620534605.3
 A Radial Artery Blood Pressure Detection Device, 2016. Patent for invention. Author NO.1. Patent number: 201621449515.0
 A Radial Artery Blood Pressure Detection Device, 2016. Patent for invention. Author NO.1. Patent number: 201621442550.x
 A Central Arterial Pressure Measurement method and system, 2016. Patent for invention. Author NO.1. Patent number: 201611219441.6
 Reconstruction of Brachial Arterial Blood Pressure based on Double Peripheral Blood Pressure, 2016. Patent for invention. Author NO.1. Patent number: 201611219443.1
 A Cerebral Blood Flow Detection Probe Stent, 2015. Patent for invention. Author NO.1. Patent number: ZL201310399921.5
 A Central Arterial Blood Pressure Measurement method and equipment, 2017. Patent for invention. Author NO.1. Patent number: 201710369140.x
 A Radial Artery Blood Pressure Detection Device, 2017. Patent for invention. Author NO.1. Patent number: 201720715018.9
Medical Signal and Image Analysis
Mathematical modeling of Physiological Systems
Research and Development of Physiological Signal Measurement System
 The ninth international meeting on Cerebral
Haemodynamic Regulation (CARNet meeting), Towards assessments of
cerebrovascular reserve for clinical application, 2019-09-12
 BRAIN & BRAIN PET 2019, PACIFICO YOKOHAMA, Towards assessments of cerebrovascular reserve for clinical application, 2019-07-04
The 5th CAS-KIST Joint Workshop, (Korea Institute of Science and
Technology – KIST, Seoul, Korea, Nov. 2009), Household intelligent
external counterpulsation system, 2009-11-01
World Congress 2009-Meidcal physics and biomedical engineering,
Tracking the dynamics of the cerebral autoregulation response to sudden
changes of PaCO2, 2009-09-07
Congress 2009-Meidcal physics and biomedical engineering 2009, Tracking
the dynamics of the cerebral autoregulation response to sudden changes
of PaCO2, 2009-09-07
Challenge 2009, (Massachusetts Institute of Technology - MIT, Cambridge,
MA 02139 USA, Sept. 2009), Forecast acute hypotension using statistical
features and SVM classifier, 2009-09-01
Proceedings of the Medicon Conference on Medical and Biological
Engineering 2004, Assessment of cerebral autoregulation using a linear
filter model: analysis of dispersion, 2008-08-23
The 7th Asian-Pacific Conference on Medical and Biological Engineering
2008, Adaptive Liver Segmentation from Multi-slice CT Scans, 2008-08-22
The 8th International Conference on Xenon CT and Related Cerebral Blood
Flow Techniques 2006, Tracing the dynamics of cerebral autoregulation
in response to step-wise changes in PaCO2 , 2006-07-01
Proceedings of the 3rd IEEE EMBSS UKRI Postgraduate Conference 2004, A
suggestion for selecting parameters in the assessment of cerebral
The First Hospital of Jilin University
蔡优飞 硕士研究生 081203-计算机应用技术
张攀登 博士研究生 081104-模式识别与智能系统
张卫 硕士研究生 085211-计算机技术
宋佳宁 硕士研究生 085211-计算机技术
吴梦露 硕士研究生 085211-计算机技术
刘宇翔 硕士研究生 085211-计算机技术
曾雨鸿 硕士研究生 085211-计算机技术
吴栋 硕士研究生 085211-计算机技术
高翔 硕士研究生 085211-计算机技术
刘锦涛 硕士研究生 085400-电子信息
赵运业 硕士研究生 085211-计算机技术
Honors & Distinctions
 Innovative Talents (flexible talents) of Jilin Province, provincial level, 2017
 Member of Youth Innovation Promotion Association, Chinese academy of sciences, 2015
 High-level Talents of Shenzhen, local leading talents, 2014
 Overseas High-level Talents of Shenzhen, class B talent of peacock program, 2014
 Best Paper Finalist, the Second prize, 2011